founder of double entry bookkeeping

... increased greatly with the elucidation of the crystal structures of the prefusion form of the PIV5 F protein [89] and of the postulated postfusion forms of the NDV and hPIV3 F proteins [90–92]. ... University of Kentucky, Lexington, KY, USA Introduction The paramyxovirus family is composed of enveloped, negative-stranded RNA viruses, many of which are major human pathogens [1]. Members of this ... promote the processes of viral attachment and virus-cell membrane fusion required for entry. Although common mechanisms of fusion protein proteolytic activation and the mech- anism of membrane fusion...

Ngày tải lên: 23/03/2014, 04:20

... a positive regulator of Ca 2+ entry. The upregulation of TRPM4b might then be involved in the further progression of the tumor. Such a possible role of A B Fig. 3. Ca 2+ release and Ca 2+ entry induced ... to act as a negative regulator of Ca 2+ entry and to be involved in the generation of oscillations of Ca 2+ influx in Jurkat T-lymphocytes. Transient overexpression of TRPM4b as an enhanced green ... influence of fused EGFP on channel function (compare Fig. 1D with Fig. 2A,B). Generation of HEK-293 clones with stable expression of TRPM4b To investigate the effect of TRPM4b expression on Ca 2+ entry...

Ngày tải lên: 23/03/2014, 09:21

... final til midnight of the last day of the month of any such announcement. The official release date of all Project Gutenberg Etexts is at Midnight, Central Time, of the last day of the stated month. ... seventeenth century, but the founder of Quebec; and it is a rich part of our heritage that he founded New France in the spirit of unselfishness, of loyalty, and of faith. BIBLIOGRAPHICAL NOTE Original ... excitement of sailing among the uncharted islands of Penobscot Bay, of watching the sun descend below the waves of Lake Huron, of attacking the Iroquois in their palisaded stronghold, of seeing...

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... remit of the local ethics committee. Prior to introduction of CPOE, local standards of prescribing existed specifying the tenets of good practice, including the avoid- ance of the use of abbreviations. An ... administered as Table 1 Types of medication errors before and after implementing CPOE Error type HWP (no. of errors and % of total errors) a CPOE (no. of errors and % of total errors) a Drug prescribed ... The types of error appeared to change with the intro- duction of CPOE. • The introduction of CPOE without decision support eliminated many minor types of error but introduced new types of error...

Ngày tải lên: 25/10/2012, 10:39

... 1 Scatter plot of number of medication prescribing errors (MPEs) at screening day according to number of drug orders per patient (24 hour screening day)Scatter plot of number of medication prescribing ... example of intercepted MPE involved the wrong prescription of a tenfold overdose of a beta-blocker, where rapid intervention of the clinical pharma- cist intercepted the administration of this ... one unit of our ICU, we implemented an ICIS with incorpo- rated CPOE and a moderate level of CDSS. The objective of this study was to evaluate and compare the incidence and severity of medication...

Ngày tải lên: 25/10/2012, 10:39

... Sarma KV, Dey D, Raychaudhuri SP. A double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin ® for treatment of osteoarthritis of the knee. Arthritis Res. Ther. ... Equal number of HCH cells was plated in each well of 96-well cell culture plate. Cells were treated with 5 ng/ml of TNFα in presence or absence of different concentrations of 5-Loxin ® or ... medical management of osteoarthritis. Part II. Osteoarthritis of the knee. American College of Rheumatology. Arthritis Rheum. 1995; 38: 1541-1546. 5. American College of Rheumatology Subcommittee...

Ngày tải lên: 25/10/2012, 11:40

... pre- valence of low back pain of 162% with an annual in- crease of 11.6%. The widely held belief that most of the episodes of low back pain will be short-lived, with 80% to 90% of these attacks ... Classification of Chronic Pain; Descriptions of Chronic Pain Syndromes and Definition of Pain Terms, 2 nd ed; Task Force on Taxonomy of the International Association for the Study of Pain. Seattle: ... pain of facet joint origin. Summary of Background Data: Lumbar facet joints have been shown as the source of chronic pain in 21% to 41% of low back patients with an average prevalence of 31%...

Ngày tải lên: 26/10/2012, 09:07

... 5 2.1.1 Entry strategy 5 2.1.2. Elements of Entry Strategies 6 2.1.3. Mode of Entry 7 2.1.4. Advantages and Disadvantages of each entry mode 11 2.2 DISCUSSION: PROBLEMS AND SOME EXTENSIONS OF THE ... a trade-off between the two types of risk. The acquisition of control is often at the expense of increased exposure to environmental risk. 2.1.4. Advantages and Disadvantages of each entry mode ... analysis of the impact of country -of- origin effects on the market entry decision would constitute a useful addition to the literature. 2.3. Environmental Technology Industry 2.3.1. An era of environmental...

Ngày tải lên: 22/04/2013, 14:21

Ngày tải lên: 05/09/2013, 14:19

... hydro- lysis of Leu-pNA. The enthalpy of ionization, DH ion ¼ 30 kJÆmol )1 , was calculated from the slope of the line. A B Fig. 4. Inhibition of SGAP by fluoride. (A) A representative plot of the Lineweaver–Burk ... This value is in the range of the expected ioniza- tion of a zinc-bound water ⁄ hydroxide in solution, DH ion of 20–30 kJÆmol )1 [52]. The enthalpy of ioniza- tion of a carboxylic group is much ... the presence of D 2 O in solution reduced the catalytic A B Fig. 5. Inhibition of SGAP by phosphate ion. (A) A representative plot of a Lineweaver–Burk plot for determination of the mode of inhibition...

Ngày tải lên: 19/02/2014, 02:20

... yeast mutants containing double deletions of supernumerary subunits. Deletion of any one of the genes encoding cyto- chrome b, subunit 7 or subunit 8 caused the loss of the other two subunits. ... unaffected. Therefore, the absence of subunit 6 appeared to alter the rates of processing of two of the redox subunits and caused minor changes in amounts of the small supernumerary subunits, ... D6/D7 double deletion strain (VZ4) exhibited the strongest defect in the assembly of the catalytic subunits of cytochrome bc 1 complex. This strain showed only 18% and 6% of the wild-type levels of...

Ngày tải lên: 19/02/2014, 12:20