formation of alpha beta unsaturated aldehydes and ketones
Báo cáo khoa học: Lysophosphatidylcholine modulates fibril formation of amyloid beta peptide doc
Ngày tải lên :
06/03/2014, 01:20
... influences fibril formation of Ab(1-40) and Ab(1-42) LPC modulates Ab fibril formation Results Effects of LPC on Ab(1-42) fibril formation To investigate the effects of LPC on Ab(1-42) fibril formation, ... times, and then the fibril formation reaction was terminated by quickly freezing the samples Assessment of Ab fibril formation on the basis of ThT fluorescence The presence of b-sheet structures and ... the effects of the vesicular form of LPC on the Ab(1-42) fibril formation process For this purpose, an increasing concentration of LPC liposomes was added to 50 lm Ab(1-42), and fibril formation...
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A study on the formation of bed forms in rivers and coastal waters
Ngày tải lên :
11/09/2015, 09:11
... sand banks and sand ridges Tidal sand banks and ridges Off, 1963; Huthance, 1982; Dyer and Huntley, 1999) are very large and nearly flow-parallel bed forms, which have wavelengths of 2-10km and ... condition for the occurrence of different types of bed configurations, such as sand banks, sand waves, sand ridges and flat bed, depending on the different values of slip factor and eddy viscosity A ... dunes and could be valid for fully developed sand waves 13 1.5 Objectives The overall objective of the present study is to seek a better understanding of the mechanism of the formation of large...
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Cytoskeleton reorganization mediates alpha beta integrin-associated actions of laminin on proliferation and survival, but not on steroidogenesis of ovine granulosa cells pdf
Ngày tải lên :
05/03/2014, 17:20
... in legend of Figure (a): numbers of cells at 144 h of culture; (b): pyknotic rates of GC at 48 h of culture (c) and (d): estradiol and progesterone secretions between 96 h and 144 h of culture ... morphology of GC cultured on substrata containing different ratios of LN and RGD peptides Effect of5 Effect of anti-α6 IgG on morphology of GC cultured on substrata containing different ratios of LN and ... Addition of cytochalasin D to the culture medium of GC from small and large follicles reduced the formation of actin stress fibers and impeded cell spreading on LN, inducing the formation of spindle-shaped...
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Báo cáo khoa học: Glycation and glycoxidation of low-density lipoproteins by glucose and low-molecular mass aldehydes Formation of modified and oxidized particles pot
Ngày tải lên :
31/03/2014, 01:20
... glucose and two aldehydes (MG and GA) in inducing lipid and protein oxidation and antioxidant depletion of LDL particles as well as glycation of the apoB protein by measuring specific parameters of ... (glycation) of LDL has been shown to occur rapidly with the aldehydes, occur in the absence of added metal ions, and depend on both the structure of the compound and its concentration Of the two aldehydes ... accumulation of AGEs, a number of studies have examined the role of low molecular mass aldehydes such as glyoxal, MG, and GA These materials are formed both as a consequence of oxidative processes and...
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Báo cáo sinh học: " Synergistic inhibition of human cytomegalovirus replication by interferon-alpha/beta and interferon-gamma" pot
Ngày tải lên :
18/06/2014, 22:20
... plaque formation, HFFs were pre-treated with 100 IU/ml each of (1) IFN-α and IFN-β, (2) IFN-α and IFN-γ or (3) IFN-β and IFN-γ As expected, the level of inhibition achieved with both IFN-α and IFN-β ... Table 1: Effect of IFN-α, IFN-β and/ or IFN-γ on HCMV plaque formation Treatment Vehicle IFN-α IFN-α IFN-β IFN-β IFN-γ IFN-γ IFN-α and IFN-β IFN-α and IFN-γ IFN-β and IFN-γ IFN-α, IFN-β and IFN-γ IU/mla ... potential of type I and type II IFN treatment An interaction index of 0.05 ± 0.03 for IFN-α and IFN-γ combined and 0.04 ± 0.01 for IFN-β and IFN-γ combined indicated a high degree of synergy...
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báo cáo hóa học:" Synergistic inhibition of human cytomegalovirus replication by interferon-alpha/beta and interferon-gamma" docx
Ngày tải lên :
20/06/2014, 04:20
... plaque formation, HFFs were pre-treated with 100 IU/ml each of (1) IFN-α and IFN-β, (2) IFN-α and IFN-γ or (3) IFN-β and IFN-γ As expected, the level of inhibition achieved with both IFN-α and IFN-β ... Table 1: Effect of IFN-α, IFN-β and/ or IFN-γ on HCMV plaque formation Treatment Vehicle IFN-α IFN-α IFN-β IFN-β IFN-γ IFN-γ IFN-α and IFN-β IFN-α and IFN-γ IFN-β and IFN-γ IFN-α, IFN-β and IFN-γ IU/mla ... potential of type I and type II IFN treatment An interaction index of 0.05 ± 0.03 for IFN-α and IFN-γ combined and 0.04 ± 0.01 for IFN-β and IFN-γ combined indicated a high degree of synergy...
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Báo cáo khoa học: "Real time PCR analyses of expression of E-cadherin, alpha-, beta- and gamma-catenin in human breast cancer for predicting clinical outcome" pps
Ngày tải lên :
09/08/2014, 07:21
... Blamey RW, Ellis IO: An immunohistochemical examination of the expression of E-cadherin, alpha- and beta/ gamma-catenins, and alpha2 - and beta1 -integrins in invasive breast cancer J Pathol 1999, ... expression of E-cadherin, α-, β- and γcatenin may persist into the later stages of breast carcinoma Siitonen et al and Oka et al found a correlation between loss of E-cadherin and the presence of nodal ... Ecahderin, α-, β- and γ-catenin between tumour and normal breast tissue Furthermore, measurement of expression of these molecules is not of prognostic value in predicting long term outcome of women with...
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Báo cáo khoa học: Protein aggregation and amyloid fibril formation prediction software from primary sequence: towards controlling the formation of bacterial inclusion bodies pot
Ngày tải lên :
06/03/2014, 00:20
... predicts 80% of amyloidogenic peptides (115 of 144 peptides) and 72% of non-amyloidogenic ones (189 of 263 peptides), with a cut-off value of 0.062, from a database of 407 amyloidogenic and non-amyloidogenic ... amyloidogenic): the scale of the packing density, and two scales of the probability of formation of backbone–backbone hydrogen bonds (assigned to donor and to acceptor residues, termed donor and acceptor ... of sequences and structures J Mol Biol 247, 536–540 Kabsch W & Sander C (1983) Dictionary of protein secondary structure: pattern recognition of hydrogen- Software for controlling formation of...
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Báo cáo khoa học: Formation of highly toxic soluble amyloid beta oligomers by the molecular chaperone prefoldin pptx
Ngày tải lên :
07/03/2014, 04:20
... SDS–PAGE also supports formation of a complex between PFD and Ab oligomers Toxicity of Ab oligomers Soluble Ab oligomers are highly cytotoxic and are found in AD brains, and are therefore considered ... Fraeyman N, Vandekerckhove J & Ampe C (2001) Prefoldin recognition motifs in the nonhomologous proteins of the actin and tubulin families J Biol Chem 276, 41023–41028 Formation of amyloid beta oligomers ... range of molecular FEBS Journal 275 (2008) 5982–5993 ª 2008 The Authors Journal compilation ª 2008 FEBS 5983 Formation of amyloid beta oligomers by prefoldin M Sakono et al the presence of PFD...
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Báo cáo khoa học: Alpha-fetoprotein antagonizes X-linked inhibitor of apoptosis protein anticaspase activity and disrupts XIAP–caspase interaction ppt
Ngày tải lên :
07/03/2014, 12:20
... field and a combination of Simplex [65] and Powell algorithms [66] Coordinates of the NMR structures of the BIR2 [49] and BIR3 [50] domains were achieved from the Protein Data Bank files: 1C9Q and ... (500 lg of total protein in 100 lL of buffer C) and activated by addition of lm cytochrome c and mm dATP for 30 at 30 °C in the presence of AFP (6 lg) The reaction mixtures were cooled and incubated ... Semenkova LN & Tatoulov EB (2005) Recombinant alpha- fetoprotein, method and means for preparation thereof, compositions on the base of thereof and use thereof International PCT No PCT ⁄ RU 2005 ⁄ 000369...
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Báo cáo khoa học: Assessment of porcine and human 16-ene-synthase, a third activity of P450c17, in the formation of an androstenol precursor doc
Ngày tải lên :
08/03/2014, 08:20
... 17aOHpreg and DHEA – and analyzed androstadienol formation from each substrate As observed in Fig 3, the biosynthesis of androstadienol in humans (A) and pigs (B) does not require prior formation of ... the specific implication of P450c17 in the formation of this metabolite Formation of androstadienol by human and porcine P450c17, with and without cyt b5 Using porcine and human P450c17 expressed ... the formation of Ó FEBS 2003 Biosynthesis of 5,16-androstadien-3b-ol by human P450c17 (Eur J Biochem 270) 1353 Fig Role of cyt b5 in the formation of androstadienol from pregnenolone by human and...
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Báo cáo khoa học: What’s in a covalent bond? On the role and formation of covalently bound flavin cofactors doc
Ngày tải lên :
16/03/2014, 01:20
... et al On the role and formation of covalently bound flavin cofactors A B Fig (A) All known types of covalent flavin–protein linkages FMN is show in black, FAD in black and gray, and known linking ... of BBE, ChitO and GOOX with only one of the two covalent linkages can be produced suggests that formation of each covalent bond is independent of each other Whereas the mechanistic features of ... stability and, in some cases, can also affect Michaelis complex formation and protein oligomerization For a richer understanding of the role of covalent flavin binding to proteins, the scope of the...
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Báo cáo khoa học: Ternary complex formation of pVHL, elongin B and elongin C visualized in living cells by a fluorescence resonance energy transfer–fluorescence lifetime imaging microscopy technique docx
Ngày tải lên :
16/03/2014, 05:20
... pVHL-cerulean and citrine-elongin C by coexpression of elongin B suggest that a conformation change of elongin C induced by binding of elongin B may occur and that this conformational change of elongin ... clarified that conformation of pVHL and ⁄ or elongin C in the absence of elongin B was different from that in the VBC complex and that conformation of elongin C was changed upon binding of elongin B ... elongin B and elongin C For stable binding of pVHL30 to elongin C, we found that the coexistence of elongin B is necessary to induce a conformational change of elongin C Results Imaging of interaction...
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Formation of silicon oxide nanowires directly from au si and pd–au si substrates
Ngày tải lên :
16/03/2014, 15:16
... morphologies of SiOx nanowires grown on Au/Si and Pd–Au/Si substrates at 1050 1C As shown in the FE-SEM images, a large number of nanowires with lengths of tens of 159 micrometers and diameters ... higher than the of SiO2 On the other hand, the atomic ratio of Si/O in the SiOx nanowires formed on the Pd–Au/Si substrate is nearly consistent with the of SiO2, indicating the formation of SiO2 nanowires ... investigate the formation behavior of SiOx nanowires on Au/Si and Pd–Au/Si substrates at a temperature above the pure Au MP of 1063 1C, we carried out thermal heating of Au/Si and Pd–Au/Si substrates...
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Báo cáo khoa học: Kinetics of intra- and intermolecular zymogen activation with formation of an enzyme–zymogen complex ppt
Ngày tải lên :
16/03/2014, 18:20
... route of intramolecular activation of the zymogen into the active enzyme, E, and one or more peptides represented by W [route (a), Scheme 3] [12,22,25–27] and a route of autocatalytic activation of ... behaviour of the species can be assumed from t ¼ Thus, if the relationships 29 and 30 [Eqns (29) and (30)] are inserted into Eqns (26) and (27), we obtain: ð33Þ and from Eqns (16) and (33) we ... fragments are released and pepsinogen is converted to pepsin X1 and X2 are the unprotonated and protonated pepsinogen, respectively, while X3* and X4* are structural isomers of the active pepsin...
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The formation of the plural noun in English and Vietnamese equivalents
Ngày tải lên :
19/03/2014, 17:10
... nouns are often found preceded by a noun phrase that serves to make them countable A piece of furniture Many pieces of furniture 22 A bit of information Numerous bits of information A bottle of wine ... Several A large amount of A great number of A large number of Some (Some) other Any A lot of Lots of No Not any (Raims, 1990:52) 26 A great deal of less Eg: She took another day off She has less free ... noun in English and Vietnamese equivalents as the topic for my graduation paper to compare the similarities and the differences between the ways of the formation of plural nouns and I hope that...
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Báo cáo khoa học: Hatching enzyme of the ovoviviparous black rockfish Sebastes schlegelii – environmental adaptation of the hatching enzyme and evolutionary aspects of formation of the pseudogene docx
Ngày tải lên :
23/03/2014, 07:20
... cycles of PCR, sufficient expression of the SsHCE1 and SsHCE2 genes was detected, and the band intensity of SsHCE2 transcripts was about half that of SsHCE1 For the wSsLCE gene, the 33 cycles of RT-PCR ... thanks to Professor F S Howell, Department of Chemistry, Faculty of Science and Technology, Sophia University, Tokyo, for reading the manuscript, and to Dr K Yamagami, former Professor of Developmental ... Expression analysis of the SsHCE1, SsHCE2 and wSsLCE genes (A) Northern blot analysis of expression of the SsHCE gene during development Arrowheads indicate the positions of 28S and 18S rRNA (B)...
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Báo cáo khoa học: N-Terminal segment of potato virus X coat protein subunits is glycosylated and mediates formation of a bound water shell on the virion surface docx
Ngày tải lên :
23/03/2014, 13:20
... Glycosylation of nuclear and cytoplasmic proteins is ubiquitous and dynamic Biochem Soc Trans 20, 264–269 Gerken, T.A., Butenhof, K.J & Shogren, R (1989) Effects of glycosylation on the conformation and ... intact wild-type and ST mutant CPs can Fig Analysis of wild-type (UK3) PVX and ST mutant preparations by SDS/PAGE (8–20% gels) Lanes and 2, UK3 PVX; lanes and 4, ST mutant; lanes and 3, CPs from ... from chromatographic peaks and 2, prepared by mild trypsin treatment of UK3 PVX virions (Fig 3) Standard MS fragmentation methods should lead to formation of ions of the peptide C-terminal fragments,...
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Báo cáo khoa học: Cytochrome P460 of Nitrosomonas europaea Formation of the heme-lysine cross-link in a heterologous host and mutagenic conversion to a non-cross-linked cytochrome c ¢ pot
Ngày tải lên :
23/03/2014, 17:21
... expressed in and purified from PA and mutants K70R and K70A heterologously expressed in and purified from PA Data were obtained as described in Materials and methods and analyzed by the methods of Wilkins ... properties and reactivity with ligands and substrates were identical with those of cytochrome P460 purified from N europaea The yield of the cytochrome was low, however, ranging from 0.2 to 0.4 mg of ... Wavelength of peaks are labeled for ferric-, ferrous- and ferrous + CO-cytochrome P460 in D, C and B, respectively Tryptic fragments of cytochromes P460 were prepared and analyzed by MALDI-TOF mass...
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