fmr 1 as an offspring genetic and a maternal environmental factor in neurodevelopmental disease
Báo cáo khoa học: Functional analysis of cell-free-produced human endothelin B receptor reveals transmembrane segment 1 as an essential area for ET-1 binding and homodimer formation pptx
Ngày tải lên :
16/03/2014, 10:20
... microdialyzers (Spectrum Laboratories, Rancho Dominguez, 3266 Ligand-binding analysis The Cy3 dye was attached at Lys9 of cET -1 Biotin was covalently attached to Cys1 of ET -1 and Lys-9, resulting in ... binding of antagonists, Wada et al proposed a 60 amino acid area spanning I138-I197, and thus covering TMS2 and TMS3, as the ET -1- binding site [44] In addition, other regions, such as TMS5, have been ... functional and structural characterization of ETB and similar GPCRs Further analysis of the identified ETB1 31 and ETB93 fragments will help to identify residues involved in ligand binding and dimerization,...
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Báo cáo khoa học: "Mesenteric rheumatoid nodules masquerading as an intra-abdominal malignancy: a case report and review of the literature" ppsx
Ngày tải lên :
09/08/2014, 04:21
... octreotide scan was negative A percutaneous CT guided needle biopsy was obtained and pathology revealed a spindle cell lesion with an inflammatory background and focal palisading necrosis; a spindle cell ... ML, Matrisian LM: Matrix metalloproteinases: biologic activity and clinical implications J Clin Oncol 2000, 18 :11 35 -11 49 Patatanian E, Thompson DF: A review of methotrexate-induced accelerated ... therapy a repeat FDG-PET/CT imaging study was obtained and demonstrated a decrease in the size of the abdominal rheumatoid nodules and no associated FDG-PET activity in the abdomen (FDG-PET negative)...
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1.Giáo án lớp 12 ban a .Học kỳ 2(Mới)
Ngày tải lên :
06/07/2013, 01:27
... quay quanh trục qua tâm vòng tròn Hình 42 .1 Sơ đồ máy phát điện xoay chiều pha có phần ứng quay, phần cảm cố đònh Máy phát điện xoay chiều ba pha a) Dòng điện xoay chiều ba pha Dòng điện xoay ... trường quay Sự quay đồng Khi quay nam châm quanh trục, từ trường nam châm gây có đường sức từ quay không gian Đó từ trường quay Nếu đặt hai cực nam châm hình chữ U kim nam châm quay nam châm chữ ... chồng lên nhau, - gọi vùng giao thoa, chúng giao thoa với tạo nên hình ảnh quan sát thấy Đặt sau M2, vùng giao thoa, quan sát E song song với M E xuất vân giao thoa, vạch song song với S1, S2 Như...
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Tài liệu Báo cáo khoa học: How disorder influences order and vice versa – mutual effects in fusion proteins containing an intrinsically disordered and a globular protein docx
Ngày tải lên :
18/02/2014, 04:20
... spectra obtained under the same conditions, as in our case [35] At 20 C, NTAIL, PNT and SIC1 share a high content of unordered stretches (5059%) and a low content in a- helices and b-strands (23% and ... Dunker AK (2009) Unfoldomics of human diseases: linking protein intrinsic disorder with diseases BMC Genomics 10 (Suppl 1) , S7 18 Durand F, Dagkessamanskaia A, Martin-Yken H, Graille M, Van TilbeurghH, ... The authors wish to thank Antonino Natalello and Silvia Maria Doglia for their assistance with the uorescence spectroscopy, as well as for critically reading the manuscript We are indebted to Maria...
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Báo cáo khoa học: Identification of sodium salicylate as an hsp inducer using a simple screening system for stress response modulators in mammalian cells pptx
Ngày tải lên :
17/03/2014, 10:20
... disorders including Alzheimer’s, polyglutamine and Parkinson’s disease are though to be caused by an accumulation of protein aggregates in the brain [24], and Hsps such as Hsp70 and Hsp40 are shown ... Biophys Acta 14 44, 13 8 14 2 16 Yasuda, K., Nakai, A. , Hatayama, T & Nagata, K (19 95) Cloning and expression of murine high molecular mass heat shock proteins, HSP105 J Biol Chem 270, 29 718 –22923 17 Arai, ... formaldehyde containing 1% CaCl2 for The dye incorporated into viable cells was extracted with 50% ethanol containing 1% acetic acid, and absorbance at 540 nm was measured Ó FEBS 2003 Sodium salicylate...
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ĐỀ THI THỬ CHUYÊN đại học VINH 2014 lần 1 đáp án môn TOÁN KHỐI a, d
Ngày tải lên :
10/04/2014, 13:52
... − 1; y2 ) Tam giác AMN vuông A ⇔ AM AN = Hay ( x1 − 1) ( x2 − 1) + y1 y2 = ⇔ ( x1 − 1) ( x2 − 1) + ( x1 + m )( x2 + m ) = ⇔ 10 x1 x2 + ( m − 9)( x1 + x2 ) + m + = (2) Áp dụng định lý Viet, ta ... Vì SH ⊥ ( ABCD ) nên SCH = ( SC , ( ABCD ) ) = 300 S H' D H Trong tam giác vuông SAD ta có SA2 = AH AD ⇔ 12 a = AD ⇒ AD = 4a; HA = 3a; HD = a C ⇒ SH = HA.HD = a ⇒ HC = SH cot 30 = 3a ⇒ CD = HC ... (3 + 3a; − 2a ) HA = ( − 3a + 1; 2a + 4) ⇒ HC = (3 + 3a; − 2a ) M N E 0,5 a = Vì AHC = 90 nên HA.HC = ⇒ a = − 19 13 *) Với a = ⇒ A( −2; 3), C (6; − 1) th a mãn B H *) Với a =...
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Báo cáo hóa học: " MMP-1 is a (pre-)invasive factor in Barrettassociated esophageal adenocarcinomas and is associated with positive lymph node status" doc
Ngày tải lên :
18/06/2014, 16:20
... Sci 20 01, 11 4(Pt 21) :3865-3872 Tanioka Y, Yoshida T, Yagawa T, Saiki Y, Takeo S, Harada T, Okazawa T, Yanai H, Okita K: Matrix metalloproteinase-7 and matrix metalloproteinase-9 are associated ... and -13 in EAC (with and without associated BE) as well as non-dysplastic BE (without evidence of intraepithelial neoplasia and carcinoma) and ESCC We aimed to indicate their potential role as ... found in a major population of proliferating MMP -1+ Barrett and EAC cells Expression of MMP -1 in proliferating (Ki-67+) cells of intestinal metaplasia and in Barrett-associated adenocarcinomas may...
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Báo cáo khoa học: "Consequences of an excess Al and a deficiency in Ca and Mg for stomatal functioning and net carbon assimilation of beech leaves" ppt
Ngày tải lên :
08/08/2014, 14:22
... between +Al (– 31% ) and –CaMg (–43%) treatments An interaction between excess Al and a deficiency in Ca and Mg was calculated for +Al–CaMg plants (–70%) The decrease in A was accompanied by a constancy ... vitality via a disturbance in stomatal regulation and leaf carbon assimilation In beech seedlings exposed to aluminium, Al accumulated in the parenchyma, and palisade cells always showed higher Al concentration ... changed mineral uptake [2, 6, 11 , 41, 42, 43] An Al-induced reduction in Ca, Mg and P concentrations was reported in roots and shoots of European beech [5, 6, 39] In contrast, K amounts in leaf...
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Báo cáo khoa hoc:" Posterior dislocation of the elbow as an unusual presentation after a total hip replacement: a case report" pdf
Ngày tải lên :
11/08/2014, 10:23
... LCLC and the importance of each component and the surrounding soft tissues and the mechanism of poster lateral rotatory instability (PLRI) continue to be investigated and debated Additional stability ... Ronald Little: Elbow dislocation during overhead skeletal traction, A case report; Clinical Orthopaedics And Related Research Number 15 4, January–Feburary 19 81 Publish with Bio Med Central and ... components and the annular ligament The lateral ulnar collateral ligament (LUCL) is described as a discrete part of the LCLC that serves to prevent postero lateral rotatory instability and varus stress...
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Báo cáo y học: "Synchronous colonic carcinomas presenting as an inguinoscrotal hernial mass: a case report" ppt
Ngày tải lên :
11/08/2014, 10:23
... general and epidural anaesthesia, the patient was placed in the supine position A midline laparotomy was performed and revealed grossly distended small and large bowel After an attempt at reducing ... generally similar to single lesions in clinical characteristics and pathological findings [3] However, one study has shown that the male:female ratio was higher and distant metastasis was more ... recovery and was discharged on day 37 The case was discussed in a multidisciplinary meeting In view of the vascular invasion, a post-discharge oncology outpatient appointment was arranged to...
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Báo cáo y học: " A woman with cystic fibrosis, severe hypoxaemia, an atrial thrombus and a patent foramen ovale: a case report" pdf
Ngày tải lên :
11/08/2014, 14:20
... investigations revealed a right-to-left intracardiac shunt as a result of a patent foramen ovale (PFO) and a right atrial thrombus Case presentation A 21- year-old Caucasian woman with CF, rheumatoid arthritis ... The patient was anticoagulated (international normalized ratio (INR) 2-3) Table Laboratory results FBC U&Es, LFTs PT, APTT, Fib Rheumatoid factor ANA Lupus anticoagulants Cardiolipin IgG/IgM Antithrombin ... were all normal The neurology resolved within 24 hours and a transient ischaemic attack (TIA) was diagnosed A transthoracic echocardiogram revealed a right atrial mass (there was no evidence of intracardiac...
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Báo cáo y học: " Low Spigelian hernia in a 6-year-old boy presenting as an incarcerated inguinal hernia: a case report" pps
Ngày tải lên :
11/08/2014, 19:21
... Spigelian hernia orifice is usually located in a well-defined area The defect develops as a ring-like opening through the fibers of the transversalis fascia and the fascia of the transversalis abdominus ... within Hesselbach's triangle, caudally and medially to the inferior epigastric vessels, are called low or lower Spigelian hernias [4] Direct inguinal hernias can also occur in this area, although ... cases Surg Today 19 94, 24 :10 81- 1084 Al-Salem AH: Congenital spigelian hernia and cryptorchidism: cause or coincidence? Pediatr Surg Int 2000, 16 :433-436 White JJ: Concomitant spigelian and inguinal...
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Báo cáo y học: "Background: Percutaneous tracheostomy (PT) has gained an increasing acceptance as an alternative to the conventional surgical tracheostomy (ST). In experienced hands, and with proper patient selection, it is safe, easy and quick." docx
Ngày tải lên :
12/08/2014, 18:20
... Marelli et al [8] n subcutaneous emphysema Pneumothorax Tracheal lesions Death 1. 6 0 1. 6 Ciaglia and Graniero [9] 17 0 1. 2 0 Friedman and Mayer [10 ] 10 0 4.0 2.0 ? 1. 0 77 2.6 0 0 Fernandez et al ... two patients, and more than 50% in one patient In 41 patients examined at least months after decannulation, Law et al [44] found a tracheal stenosis of 10 % in four asymptomatic patients by means ... No late complication was observed by Fantoni and Ripamonti [7] in nine autopsies and 20 adults after decannulation However, the duration of cannulation was not mentioned An adequate comparative...
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Need as an auxiliary verb and an ordinary verb
Ngày tải lên :
12/07/2015, 20:15
... When referring to Past time, need is followed by the perfect infinitive: He need not have lost his temper They need not have come all this way We need not have waited for his approval Be first ... We need not have waited for his approval Be first to know when grammar rules change! Sign up to our newsletter here: englishgrammar.org (It's free) Powered by TCPDF (www.tcpdf.org) ...
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Need as an auxiliary verb and an ordinary verb
Ngày tải lên :
29/08/2016, 22:44
... When referring to Past time, need is followed by the perfect infinitive: He need not have lost his temper They need not have come all this way We need not have waited for his approval Stay on top ... need not have waited for his approval Stay on top of your writing! Download our grammar guide from www.englishgrammar.org to stay up-to-date Powered by TCPDF (www.tcpdf.org) ...
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Báo cáo khoa học: Insulin induces heme oxygenase-1 through the phosphatidylinositol 3-kinase/Akt pathway and the Nrf2 transcription factor in renal cells pptx
Ngày tải lên :
07/03/2014, 12:20
... treated and lysed Adequacy of effect was ascertained with western blot analysis with anti-Nrf2 Statistical analysis Data are presented as means and standard error of the mean (SEM) Statistical ... [18 ], and subsequently in rodent cardiac [19 ,20] and renal transplantation models [ 21] Two important mechanisms of CO protection involving p38 mitogen-activated protein kinase (MAPK) and guanylyl ... risk factors and implications for renal allograft survival Transplantation 63, 968–974 Shoskes DA & Halloran PF (19 96) Delayed graft function in renal transplantation: etiology, management and...
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Báo cáo khoa học: The )148 to )124 region of c-jun interacts with a positive regulatory factor in rat liver and enhances transcription Dipali Sharma*, Sujata Ohri and Aparna Dixit ppt
Ngày tải lên :
23/03/2014, 20:22
... maintain its DNA-binding domain in an active conformation RLjunRP is an 40 kDa protein that forms an 80-kDa protein–DNA adduct To assess approximate molecular mass of the factors interacting ... Phosphatase-treated nuclear extracts were assayed for their DNA-binding capacity in standard EMSA UV crosslinking of DNA–protein adduct The EMSA reaction was carried out using ng labelled Jun)25 and ... containing maximum RNA polymerase II activity and essential transcription factors was used in in vitro transcription assay and electrophoretic mobility shift assay (EMSA) In vitro run-off transcription...
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báo cáo hóa học:" Anonymous HIV workplace surveys as an advocacy tool for affordable private health insurance in Namibia" pot
Ngày tải lên :
20/06/2014, 08:20
... unable to pay for health insurance Second, raising HIV awareness and knowledge remains important considering the large amount of stigma that remains a major issue in many sub-Saharan African ... was reviewed Data were obtained from several databases that record data on insurance policies of the main providers in Namibia PharmAccess has access to these databases as part of its external ... disability, the demands on health care infrastructure and capacity are expected to further increase [5] The current HIV -1 prevention and treatment strategies in sub-Saharan Africa are largely being implemented...
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Báo cáo hóa học: " Novel Strategy to Fabricate PLA/Au Nanocomposites as an Efficient Drug Carrier for Human Leukemia Cells in Vitro" pdf
Ngày tải lên :
21/06/2014, 08:20
... IIIa Multimode AFM (Digital Instruments, Santa Barbara, CA, USA) operating in air at room temperature MTT Assay Experimental Section Reagents Daunorubicin was purchased from Nanjing Pharmacy Factory ... the reaction color did not change Ultrapure water was added in which the final volume was 10 0 mL and the diameter of Au nanoparticle was about 15 nm The other reagents were analytical grade For ... Figures and 2, the AFM images of PLA nanofibers, Au nanoparticles and the blending of the PLA/Au nanocomposites with daunorubicin demonstrate that upon blending of daunorubicin with the PLA/Au nanocomposites,...
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