fluid distribution in the human body

Ngày tải lên: 18/12/2013, 21:45

... Plasma Proteins Having entered the blood, drugs may bind to the protein molecules that are present in abundance, resulting in the formation of drug-protein complexes. Protein binding involves primarily ... from binding sites on plasma proteins. Binding to plasma pro- tein is equivalent to a depot in prolong- ing the duration of the effect by retard- ing elimination, whereas the intensity of the effect ... area in the sche- matic drawing, bottom left) and acts as a continuous barrier between the two spaces separated by the cell layer – in the case of the gut, the intestinal lumen (dark blue) and the...

Ngày tải lên: 22/01/2014, 00:20

... brain 65. liver 58. spinal cord 66. stomach 59. throat 67. intestines 60. windpipe 68. vein 61. esophagus 69. artery 62. muscle 70. kidney 63. lung 71. pancreas 64. heart 72. bladder The Human ... 39. beard The Eye - D 44. eyebrow 45. eyelid 46. eyelashes 47. iris 48. pupil The Foot - E 49. ankle 53. big toe 50. heel 54. toe 51. instep 55. little toe 52. ball 56. toenail The Internal Organs ... esophagus 69. artery 62. muscle 70. kidney 63. lung 71. pancreas 64. heart 72. bladder The Human Body February 28th, 2009 Goto comments Leave a comment ...

Ngày tải lên: 17/09/2013, 01:10

... like they expected a receipt. — K IN H UBBARD , humorist (1868–1930) Two Sides of the Same Coin In Mandarin the words buy and sell are the same in the spo- ken language, differing only in the ... actually the name of a muscle. Its claim to fame is that it’s the largest muscle in the human body. Can you guess where one can find it? Hint: you sit on it. An incredible machine, the human body ... in the face of overwhelming complexity.” The Sciences MISCELLANEOUS WORDS 99 In a perfect union the man and woman are like a strung bow. Who is to say whether the string bends the bow, or the...

Ngày tải lên: 25/10/2013, 16:20

Ngày tải lên: 12/12/2013, 00:03

... by growth in iron-rich media. We have also shown that the increase in the prooxidant state caused by iron loading has an impact in protein integrity, as indicated by an increase in protein-bound ... localizes in the cytoplasm of human epithelial cells of the gastrointestinal tract and liver, two central organs in the regulation of iron metabolism [20,21]. After their synthesis in the endo- plasmic ... phosphatidylserine in the plasma membrane with a third of these cells also expressing CD1d (Fig. 6A, left dot-plot). Interestingly, the increase in phosphatidylserine expression by HepG2 cells grown in iron-rich...

Ngày tải lên: 19/02/2014, 16:20

... antibody, appeared at 90 kDa. Loading control was performed using an antibody against b-actin, which produced a band at 42 kDa. The data indicate the intensity of the HLA-G band related to the ... an increase in binding capacity [25]. Identification of nitration site in the extracellular domain of ILT2 In the extracellular domain of ILT2, there are several Tyr residues that participate in ... directly in the interaction with HLA-G [3,19] and Tyr35 is located in the very vicinity of Tyr38. These modifications should affect the binding pocket directly. Furthermore, Tyr99 stabilizes the angle between...

Ngày tải lên: 07/03/2014, 02:20

... the initial GS activity was maintained (116.5 ± 7.3% of the initial activity). The protective effect was abolished when the recom- binant protein was heat-inactivated by autoclaving, suggesting ... FEBS protein bound to the agarose. This binding was con- firmed by the observation that only a trace of the pro- tein was left in the unbound fraction. Pre-incubation of the recombinant protein with ... but the binding was not affected by preincubation of the protein with FP. These results also indicate that Pf1-Cys-Prx can bind to FP at pH 7.4, which is the pH of the parasite cytosol. The fact...

Ngày tải lên: 07/03/2014, 17:20

... gins, or delays the analysis, i.e., determines structure only after further material of the string is received. The other feature is whether the model constructs just a single analysis of the ... garden-pathing at the point of disambiguation (the word "to"). In the present experiment, sentences in which the "that"-clause was disambiguated immedi- ately following the beginning ... GSP does so in a limited way. Their Final Ar- guments principle permits a delay in the determina- tion of the attachment of particular constituents into the overall structure of the sentence...

Ngày tải lên: 08/03/2014, 18:20

... provides the residues for binding the coenzyme. The C-terminal domain has a lar- gely a-helical structure, and serves mainly in substrate binding. The active site is located in the interdomain cleft, ... (40–800 mm), and so the choice of the constant level of Fru was not critical for determination of D K m (1.23 ± 0.15). The KIE data in Table 4 are instrumen- tal in delineating the kinetic mechanism ... Considering the uncertainty in the in vivo levels of NADH, Fru and Man-ol1P used, we per- formed a sensitivity analysis in which the effects of changes in intracellular reactant concentrations on the thermodynamic...

Ngày tải lên: 14/03/2014, 23:20

... protein of SUMO modification [32,33]. The hinge region lysine, residue 289 in the mouse and 224 in the human LRH-1, was the major SUMO conjugation site. Sumoylation of LRH-1 is associated with the ... Nuclear body localization of LRH-1 was suppressed by forskolin and cholera toxin. Forskolin treatment obviously in uences the expression of members involved in the SUMO pathway. The results obtained ... is attenuated by the cAMP signaling pathway. Our studies further indicate a novel regulatory mechanism of cAMP signaling for altering the sumoylation cycle, involving modulating the expression...

Ngày tải lên: 23/03/2014, 06:20

... repression. These results thus demon- strate a strong conservation in the binding of C-terminal binding protein- interacting domains despite great variability in their amino acid sequences. Finally, ... cleft in the CtBP N-terminal region. Point mutation of the only invariant residue in the CtBP-interacting domain is sufficient to abolish the HIC1–CtBP interaction Having established that the interaction ... CtBP (C-ter- minal binding protein) through a conserved GLDLSKK motif, a variant of the consensus C-terminal binding protein interaction domain PxDLSxK ⁄ R. Here, we show that HIC1 interacts with...

Ngày tải lên: 23/03/2014, 10:21

... not contained in any of the other dengue genomes considered). Fig. 4. Distribution of the percentage of human- blind 22-mers per genome that are unique (i.e. not contained in any of the other den- gue ... serotype of the virus (present in all strains of the serotype), and (d) unique to each individual viral strain’s genome (present in the strain and absent from all other strains). The results ... 22 Present in all dengue; absence in human not considered 201484200 Human- blindonechangeaway 81282200 Human- blind two changes away 0 0 20000 Human- blind three changes away 0 0 00000 Human- blindfourchangesaway...

Ngày tải lên: 23/03/2014, 11:20

... TRAIL on the liver carcinoma cells QGY-7703 To investigate the apoptotic function of TRAIL containing the extracellular domain (amino acids 114–281) of the human liver cancer cell line, QGY-7703 ... CA, USA). The cells were maintained in RPMI-1640 containing 10% heat-inactivated bovine serum, 1 m ML -glutamine, 100 UÆml )1 penicillin and 100 lgÆml )1 streptomycin (Life Technologies, Inc. Grand Island, ... less effective than the expected effects based on tests of the compounds individually. Simply put, the point representing the dose combination lying on, below, or above the straight line represents...

Ngày tải lên: 23/03/2014, 17:22

... between academic and industrial engi- neers and whether the ideas expressed influence research in the coming years. xii In Phase Equilibria and Fluid Properties in the Chemical Industry; Storvick, ... FOREWORD The ACS SYMPOSIUM SERIES was founded in 1974 to provide a medium for publishing symposia quickly in book form. The format of the SERIES parallels that of the continuing ADVANCES IN ... with real fluid behavior are moving quickly toward producing an effective equation of state for liquids. These efforts are in the hands of the theo- retician today, but further development...

Ngày tải lên: 02/04/2014, 16:19

... of the Head and Neck 1. The Veins of the Exterior of the Head and Face 2. The Veins of the Neck 3. The Diploic Veins 4. The Veins of the Brain 5. The Sinuses of the Dura Mater. Ophthalmic Veins ... Connections of the Spinal Nerves f. Pathways from the Brain to the Spinal Cord g. The Meninges of the Brain and Medulla Spinalis h. The Cerebrospinal Fluid 5. The Cranial Nerves a. The Olfactory ... piece of the body, during the sixth month; in the second and third pieces of the body, during the seventh month of fetal life; in its fourth piece, during the first year after birth; and in the xiphoid...

Ngày tải lên: 08/04/2014, 12:35