fk+506+binding+protein+fkbp+12

... singlestranded RNA -binding motif in hnRNP U, is reported to be the G-quadruplex RNA -binding motif in the fragile X mental retardation protein (FMRP) and the G-quadruplex DNA -binding motif in nucleolin ... is an RNAbinding protein involved in nerve cell differentiation, interacts with the G-quartet forming RNA [22–25] In addition, the RBD and the RGG domain of nucleolin, a DNA -binding protein contributing ... and binding activity of the hnRNP U protein: binding RNA through RGG box EMBO J 11, 2655– 2665 Darnell JC, Jensen KB, Jin P, Brown V, Warren ST & Darnell RB (2001) Fragile X mental retardation protein...

Ngày tải lên: 15/02/2014, 01:20

... reticuli alpha-chitin -binding protein CHB2 and its gene Microbiology 144 (Pt 5), 129 1129 7 Folders J, Tommassen J, van Loon LC & Bitter W (2000) Identication of a chitin -binding protein secreted by ... 2411 L lactis chitinase and chitin -binding protein G Vaaje-Kolstad et al lg of target protein) or activated factor X (Merck Chemicals Ltd.; U per 70 lg of target protein) to puried His-tagged LlChi18A ... binding of the protein to the reaction vessels (buffer + 400 lgặmL)1 LlCBP33A; the values derived from this control sample were considered to represent 0% binding) For further verication of binding, ...

Ngày tải lên: 18/02/2014, 08:20

... mRNA poly (A) -binding protein: localization, abundance and RNA -binding specificity Exp Cell Res 211, 400–407 Afonina E, Stauber R & Pavlakis GN (1998) The human poly (A) -binding protein shuttles ... highly specific peptidebinding domain found in poly(A) -binding protein and a HECT ubiquitin ligase EMBO J 23, 272–281 Craig A (1998) Interaction of polyadenylate -binding protein with the elF4G ... J 273, 5678–5690 12 Parker R & Song H (2004) The enzymes and control of mRNA turnover Nat Struct Mol Biol 11, 121 127 13 Bag J (2001) Feedback inhibition of poly (A) -binding protein mRNA translation:...

Ngày tải lên: 18/02/2014, 12:20

... 299-residue protein with unknown structure At3g16450.1 has been classified as a myrosinase -binding protein- like protein Myrosinase is a glucosinolatedegrading enzyme [4], and myrosinase -binding protein ... YDSDIITSITFSTFKGKTSPPYG -LG FEEFQLDYPSEYITAVEGTYDKIFG FETEVINMLRFKTNK-KTSPPFG -LG TEEFVVD-PEDYITSVKIYYEKLFG SPIEIVTALIFKTFKGKTSQPFG -LG TEEFEID-PEDYITYVKVYYEKLFG SPIEIVTALIFKTFKGKTSQPFG -LG ... dependent on the presence of myrosinase -binding proteins Plant Physiol 129 , 1592– 1599 Taipalensuu J, Eriksson S & Rask L (1997) The myrosinase -binding protein from Brassica napus seeds possesses...

Ngày tải lên: 18/02/2014, 14:20

... Genet 9, 121 9 122 6 Yoon T & Cowan JA (2003) Iron–sulfur cluster biosynthesis Characterization of frataxin as an iron donor for assembly of [2Fe)2S] clusters in ISU-type proteins J Am Chem Soc 125 , ... paramagnetic effects around the binding site: they induce a line ˚ broadening of 1–100 Hz in nuclei located within A of the binding site, depending on the molecular mass of the protein and the strength ... ion was therefore carried out at very low ion ⁄ protein ratios The first point was Metal -binding properties of CyaY recorded at a 0.05 : ion ⁄ protein ratio, and a small broadening effect was...

Ngày tải lên: 18/02/2014, 16:20

... the CD -binding protein would participate in the CD transport Crystal structures of several sugar -binding proteins, such as EcoMBP [15–19], Thermococcus litoralis trehalose ⁄ maltose -binding protein ... participates in binding to not only linear maltooligosaccharides but also to CDs, and thus was designated cyclo ⁄ maltodextrin -binding protein (TvuCMBP) The bacterial sugar -binding protein is a ... Pyrococcus furiosus maltodextrin -binding protein [21] and Alicyclobacillus acidocaldarius maltose ⁄ maltodextrinbinding protein [22], have been determined These proteins share a common structural...

Ngày tải lên: 19/02/2014, 00:20

... level The protein encoded by bc1534 is classified as a LmbE-related protein and hereafter will be referred to as BcZBP (B cereus zinc -binding protein) The N-terminal part of BcZBP (residues 7 124 ) ... (str A2 012) (i.e bant_01002171, bant_01004539 and bant_01004184) [4] All of them code for uncharacterized proteins that share sequence identities of 96%, 28% and 24%, respectively, with the protein ... the acetate moiety The protein coordinates zinc with the Nd atom of His12, one of the Od atoms of Asp15 and the Ne atom of His113 His113 protrudes from helix a4 whereas His12 and Asp15 both belong...

Ngày tải lên: 19/02/2014, 00:20

... phosphatidylethanolamine -binding protein from bovine brain: a novel structural class of phospholipid -binding proteins Structure 6, 125 5 126 5 Banfield MJ & Brady RL (2000) The structure of Antirrhinum centroradialis protein ... homology of rat and human HCNP precursor proteins, bovine phosphatidylethanolamine -binding protein and rat 23-kDa protein associated with the opioid -binding protein Brain Res Mol Brain Res 30, 381–384 ... GTPase-activating protein in Saccharomyces cerevisiae Eukaryot Cell 3, 459–470 ` 12 Schoentgen F & Jolles P (1995) From structure to function: possible biological roles of a new widespread protein family binding...

Ngày tải lên: 19/02/2014, 05:20

... Various extracellular proteinases regulate cellular functions by degrading or processing protein substrates including extracellular matrix proteins, growth factors and cell surface proteins For example, ... Insulin-like growth factors and their binding proteins: biological actions Endocrinol Rev 16, 3–34 Rechler MM (1993) Insulin-like growth factor binding proteins Vitam Horm Rev 47, 1–114 Kim HS, ... insulin-like growth factor binding proteins (IGFBPs): characterization of connective tissue growth factor as a member of the IGFBP superfamily Proc Natl Acad Sci USA 94, 129 81 129 86 Akaogi K, Okabe...

Ngày tải lên: 19/02/2014, 07:20

... Sepharose-CL-4B Binding studies were carried out as described earlier [3] with liposome associated binding protein using [125 I]laminin as the ligand Separation of integral membrane proteins, electrophoresis ... G -protein [32] [125 I]TID has been a useful tool for identifying transmembrane domains of proteins [17,33,34] [125 I]TID partitions efficiently into membrane lipid bilayers and photolabeling of proteins ... be an integral membrane protein External orientation of the laminin -binding moiety Fig Identification of LBP from radioiodinated Leishmania membrane proteins Membrane proteins, isolated from surface...

Ngày tải lên: 21/02/2014, 00:20

... 1068 128 1 1068 X 128 1 1068 128 1 1068 128 1 TRPS1 10 20 30 40 50 Fold repression Fig CtBP binding domains of Ikaros, Eos and TRPS1 act as potent repression domains Plasmids encoding Gal4 DNA -binding ... PXDLSlike motif for the three proteins in (A) are shown Amino-acid numbers are indicated Ikaros has also been shown to bind coregulatory proteins of the C-terminal -binding protein (CtBP) family (reviewed ... generally the PXDLS motif on the DNA -binding protein slots into a putative PXDLS-accepting pocket within CtBP In the cases where the PXDLS motif is not required for binding and other contacts are made,...

Ngày tải lên: 21/02/2014, 01:21

... The receptor is formed by two proteins: TFbinding protein A (TbpA) and TF -binding protein B (TbpB) TbpA is similar to a classical receptor; it is an integral membrane protein that depends on TonB ... transferrin binding proteins More than 20 years ago, a putative TF binding protein in L infantum promastigotes was reported [Voyiatzaki and Soteriadou, 1990] The binding of human iron-free 125 I-TF ... from animals to humans Int J Parasitol 2000 Nov;30 (12- 13) :121 7-58 Testa U Proteins of iron metabolism CRC Press; 2002 Transferrin Binding Proteins as a Means to Obtain Iron in Parasitic Protozoa...

Ngày tải lên: 21/02/2014, 23:20

... ª 2011 FEBS 2363 A domain of fibronectin -binding protein B A F M Burke et al RU 100 A N 80 Response 40 GBD 9 10 11 12 13 14 607 126 5 126 6–1908 V 15 10 11 12 C 1918–2477 B rFnBPB309–480 20 N29 rFnBPB163–480 ... reduced binding to Fn when compared with the wild-type rN2N3 protein, which reached a maximum binding level of 95 RU (Fig 7A) Although rFnBPB163–308 reached a maximum binding level of 12 RU, rFnBPB309–480 ... gelatin -binding fragment (GBD) and fragments 607 126 5, 126 6–1908 and 1913–2477 were used in this study and are labelled (B) Equal amounts (10 or nM) of whole Fn and Fn fragments N29, BCD, 607 126 5, 126 6–1908...

Ngày tải lên: 06/03/2014, 00:20

... cytoplasmic protein X, and the protein X–Gc fusion protein and integral membrane protein Y in its native form were coexpressed in a ste18D strain The interaction between protein X–Gc and protein ... homologous protein) b-Catenin–CBP (CREB -binding protein) JNK (c-Jun N-terminal kinase)–IKAP (IjB kinase complex-associated protein) ErbB (EGFR)–Grb2 c-Myc–Krim-1A or c-Myc–Krim-1B (Krab box proteins ... – protein protein interactions Yeast–mammal chimeric Ga system Medici et al [78] constructed an intelligent system for analysis of protein protein interactions by managing heterotrimeric G-protein...

Ngày tải lên: 06/03/2014, 11:20

... with 1F12F1 [24] The crystal structure of Fn -binding sites from FnBPA in complex with Fn domains has been reported [25] S aureus contains a second Fn -binding protein, termed Fn -binding protein ... S aureus Structured digital abstract: l MINT-7991189, MINT-79 9122 7, MINT-7991305, MINT-79 9129 2, MINT-79 9127 9, MINT79 9126 6, MINT-79 9125 3, MINT-7991622: fnbA (uniprotkb:P14738) binds (MI:0407) to ... disordered region with Fn -binding activity FnBPA also possesses fibrinogen -binding [22] and tropoelastin -binding abilities, mediated by the N-terminal A-domain region [23] The Fn -binding moiety is organized...

Ngày tải lên: 06/03/2014, 22:21

... peptides 70-113 +P 70-113 +2P 114 -127 +P 157-175 +P Glu C peptides 83-108 +2P 93-100 +P 93-103 +P 93-103 +2P 93-108 +P 100-111 +P 109 -121 +P 109 -122 +P 112- 121 +P 113 -121 +P 161-172 +P Tryptic peptides ... factor (IGF) binding protein- 1 decreases plasma free IGF-I and muscle protein synthesis Endocrinology 144, 3922–3933 Westwood M (1999) Role of insulin-like growth factor binding protein in human ... Cellular actions of the insulin growth factor binding proteins Endocr Rev 23, 824–854 Baxter RC (2000) Insulin-like growth factor (IGF-) binding proteins: interactions with IGFs and intrinsic...

Ngày tải lên: 07/03/2014, 00:20

... damage -binding factors in vivo Mol Cell Biol 21, 6782–6795 Brand M, Moggs JG, Oulad-Abdelghani M, Lejeune F, Dilworth FJ, Stevenin J, Almouzni G & Tora L (2001) UV-damaged DNA -binding protein ... of the published data relate to HMGNs as a family of proteins involved in transcription regulation [15] The HMGN family comprises structural proteins that specifically recognize the generic structure ... N2 –/–) Nh 43 (N1a –/–; N2 –/–) D108-1 (N2 –/–) 8bsr8 (N1a –/–) 140 Cell survival (%) 120 100 80 60 40 20 0 12 UV dose to cells (J·m–2) Fig Loss of HMGN variants leads to UV hypersensitivity in...

Ngày tải lên: 07/03/2014, 00:20

... polypyrimidine-tract binding protein (PTB) functions 12 13 14 15 16 17 specifically in the male germline EMBO J 22, 2924– 2933 Hamon S, Le Sommer C, Mereau A, Allo MR & Hardy S (2004) Polypyrimidine tract -binding ... tract -binding protein promotes insulin secretory granule biogenesis Nat Cell Biol 6, 207–214 Kosinski PA, Laughlin J, Singh K & Covey LR (2003) A complex containing polypyrimidine tract -binding protein ... polypyrimidine tract binding protein and upstream of N-ras Mol Cell Biol 21, 3364–3374 Polydorides AD, Okano HJ, Yang YY, Stefani G & Darnell RB (2000) A brain-enriched polypyrimidine tract -binding protein...

Ngày tải lên: 07/03/2014, 00:20

... mitochondrial-encoded proteins) In particular, the synthesis of ND1, ND6 and CoxIII ⁄ ATP6, was enhanced approximately two-fold by the combination of CREB and cAMP or cPKA A B 400 200 200 100 0 250 250 250 125 125 ... cPKA A B 400 200 200 100 0 250 250 250 125 125 125 0 200 100 Fig Effect of CREB, cAMP and cPKA on mitochondrial protein synthesis Mitochondrial protein synthesis was performed in a rat liver ... mitochondrial proteins For other details, see Experimental procedures CREB and mitochondrial protein synthesis Fig 5, in which a higher amount of [35S]methionine was used in the mitochondrial protein...

Ngày tải lên: 07/03/2014, 02:20

... and A novel human (GCC)n -binding protein p68 are DNA -binding proteins that interact specifically with composite cis-acting element of rpL32 Identification of rpL32 -binding protein p56 by MALDI-TOF ... human and mouse nuclear proteins To date, only one (GCC)n -binding protein, p20, has been characterized [16,18,22] The p20 protein was first detected in HeLa cells as a protein interacting with ... (i.e Sp1, Egr1, WT1) [17] Thus, low affinity binding of short (GCC)n repeats to (GCC)n -binding proteins may be compensated for by cooperative protein protein interactions with transcription factors...

Ngày tải lên: 07/03/2014, 05:20