... potential for fire, explosion, and reactivity Known acute and chronic health effects and related health information This information is to include signs and symptoms of exposure and any medical ... standard in 1984 Chemical manufacturers, importers, and distributors were required to comply with the standard by November 25, 1985, and affected employers by May 25, 1986 Originally, the standard ... recommendations are not mandatory and are in several instances out of date The standard is a performance standard which allows a great deal of flexibility on the part of the employer and employee As noted...
Ngày tải lên: 11/08/2014, 04:20
... interactions with substrates and ⁄ or inhibitors Results and Discussion Characterization of cDNAs and trypsin-like deduced protein sequences The three partial cDNA fragments and the 5¢ and 3¢ ends obtained ... families I, II and III, respectively, in the shrimp Litopenaeus vannamei However, 44 nucleotide substitutions were observed between PaTry3 and both PaTry1 and PaTry2, leading to 23 and 26 amino ... crustacean trypsins [2,11] In addition, we hypothesize that Cys71 and Cys252 in Patry1a, PaTry1b, PaTry2 and PaTry3 sequences, and Cys71 and Cys267 in PaTry4 are free Cys As in crayfish [8], there is...
Ngày tải lên: 23/03/2014, 03:20
Báo cáo khoa học: Polysaccharide binding sites in hyaluronate lyase – crystal structures of native phage–encoded hyaluronate lyase and its complexes with ascorbic acid and lactose docx
... regions and associated structural changes upon ligand binding have not been characterized so far To understand the structure and function relationship of unusually structured triple-stranded hyaluronate ... bridge between lactose atom and protein atoms have been observed between the protein and the ligand (Table 3) The second lactose molecule is held near b-strands b7, b8 and b9 (Table 3) At this position, ... AsnA186, PheB197, SerB198, ThrB204, GlnC214 and ThrA228, and water molecules, W73, W101 and W103 The third lactose molecule is located near the b-strands b11, b12 and b13 (Table 3) It interacts with...
Ngày tải lên: 23/03/2014, 04:21
Báo cáo sinh học: " Rotavirus nonstructural protein 1 antagonizes innate immune response by interacting with retinoic acid inducible gene I" pdf
... dsRNA to prevent their detection by RIG-I and MDA-5 [30] Some other viruses, such as rhinovirus, echovirus, and encephalomyocarditis virus, encode proteases that cleave RIG-I and attenuate RIG-I ... Rotaviruses were detected by RIG-I and/ or MDA-5 when they enter host cells Then RIG-I and/ or MDA5 associate with MAVS/IPS-1, and antiviral signals are propagated to IRF3 and NF-κB Rotavirus NSP1 mediates ... contributions LQ, LR, ZZ, XL, LC, QX and ZS carried out the experiments LQ, LR, ZZ, JW and TH designed the research, wrote the manuscript and reviewed the drafts All authors read and approved the final manuscript...
Ngày tải lên: 18/06/2014, 18:20
báo cáo hóa học:" Arthroscopic debridement of the osteoarthritic knee combined with hyaluronic acid (Orthovisc®) treatment: A case series and review of the literature" docx
... concomitant HA delivery and arthroscopic debridement for OA of the knee utilizing health related questionnaires (WOMAC and SF-36) Methods and materials This investigation was approved by and performed ... investigating the safety and efficacy of HA injections show that the standard dosing is safe and effective [25,31,32] Our pilot study results showed at least equivalent efficacy and safety at the six-month ... meta-analysis found that WOMAC pain scores peaked between and 13 weeks and tended to deteriorate towards baseline over 52 weeks Brandt et al [32] in a randomized control trial of 226 patients found that...
Ngày tải lên: 20/06/2014, 01:20
báo cáo hóa học:" Stabilization of mid-sized silicon nanoparticles by functionalization with acrylic acid" pptx
... carried out the FTIR and DLS measurements, drafted the manuscript, and participated in the design of experiments HK and HN carried out the XPS measurements and interpretation and contributed to ... provided by DLS and Zeta-potential measurements FTIR and XPS measurements were used to assess the functionalization quality and elucidated the binding mechanism between acrylic acid and silicon nanoparticles ... Acknowledgments We thank Anna Elsukova and Zi-An Li for providing the TEM pictures and Alice Sandmann (all University of Duisburg-Essen) for her support with the DLS and Zeta-potential measurements...
Ngày tải lên: 21/06/2014, 17:20
Titration with Oxalic Acid ppsx
... into the face Place the buret and buret stand on the floor if necessary Acids are corrosive and bases are caustic Wipe up spills and drips immediately with wet towels, and the dry Wash affected skin ... and notify your teacher Burets are cumbersome and break easily – handle them with care Procedure Part A Preparation Put your goggles on While one lab partner prepares the oxalic acid (Steps and ... buret to the support stand Obtain 50-60mL of sodium hydroxide (NaOH) solution, unknown, in a 100 mL beaker Position the buret so that the top is below your eye level and place and empty beaker under...
Ngày tải lên: 07/07/2014, 00:20
Báo cáo y học: "Safety and Effectiveness of two treatment regimes with tranexamic acid to minimize inflammatory response in elective cardiopulmonary bypass patients: a randomized double-blind, dosedependent, phase IV clinical trial." pdf
... interpretation, and drafting the manuscript MB, LL, RP and MLM, were responsible for data collection and processing blood simples during the study and provided useful suggestions PM and JMR, was ... coagulation-fibrinolysis parameters and interpretation JMB and BM, was responsible for determination of IL-6 and interpretation RM was the surgical team and was responsible for preoperative clinical and analytical ... Qualitative variables are expressed as frequencies and percentages and quantitative variables as mean and 95% confidence interval (CI), or median and interquartile range P values of < 0.05 were...
Ngày tải lên: 10/08/2014, 09:22
Báo cáo khoa học: " Replication of avian, human and swine influenza viruses in porcine respiratory explants and association with sialic acid distribution" pot
... of viral attachment (PVA) of human and AIVs in pig tissues, we focused on the expression in epithelial cells and glands of NE, TE and BE and in bronchioles and alveoli of LE An overview of the ... between the examined duck and chicken viruses Overall, the differences between the virus yields of swine and AIVs were statistical significant in NE, TE and BE at 24 and 48 hpi and in LE at 24 hpi ... agglutinin (SNA) and Maackia amurensis agglutinin I and II (MAL-I and MAL-II) in the porcine respiratory explants SNA NE Epithelium MAL-I MAL-II ++ - +/- Glands TE +/- + + Epithelium ++ - +/- Glands BE...
Ngày tải lên: 12/08/2014, 04:21
Báo cáo y học: "Conventional or physicochemical approach in intensive care unit patients with metabolic acidos" ppsx
... nonvolatile weak acid (primarily serum proteins and phosphate), and the carbon dioxide tension (pCO2) [4,5] Although the Stewart approach may give a better understanding of the mechanisms that underlie ... hyperlactatemia and the presence of other unmeasured strong anions Methods The study was conducted in a single, mixed medical and surgical ICU of the Jeroen Bosch Hospital, ‘s-Hertogenbosch, The Netherlands ... phosphate and albumin in a single arterial blood sample Bicarbonate was calculated using the Henderson–Hasselbach equation (pH = 6.1 + log ([HCO3–]/0.0301 PaCO2) and the SBE using the Siggaard–Andersen...
Ngày tải lên: 12/08/2014, 19:22
Báo cáo khoa học: "Circulating anions usually associated with the Krebs cycle in patients with metabolic acidosis" potx
... levels of isocitrate and α-ketoglutarate were measured using enzyme assays developed by ourselves using isocitrate dehydrogenase and α-ketoglutarate dehydrogenase, respectively, and their associated ... Chemicals, Poole, UK) All the enzymatic assays relied upon the interconversion of NAD+ and NADH or NADP+ and NADPH and used the change in absorbance due to the reduced co-enzyme at 340 nm Oxaloacetate ... (approximately 69 s) in aqueous systems at near physiological pH [6] All data are presented as mean ± standard deviation Unless stated otherwise, the data are normally distributed and statistical analysis...
Ngày tải lên: 12/08/2014, 22:22
Báo cáo y học: "Oxygen consumption is depressed in patients with lactic acidosis due to biguanide intoxication" docx
... participated in its design and coordination, performed the statistical analysis and drafted the manuscript RR, PT, and SV participated in study design and data collection MS, AR, and GF participated ... 0.05) and SOFA (12 ± vs ± 2; P < 0.05) scores on admission Main results are reported in Table and Figures and Systemic O2 consumption, monitored in 11 patients, was abnormally low on day and normalized ... decrease gluconeogenesis (and lactate clearance) and may potentially increase glucose consumption (and lactate production) [10,12,13] Although the effect on organs and tissues other than the...
Ngày tải lên: 13/08/2014, 20:21
Iron(III) and copper(II) complexes bearing 8 quinolinol with amino acids mixed ligands synthesis, characterization and antibacterial investigation
... a primary ligand can exhibit biological activity (Noorulla and Sreenivasulu, 2011; Singh et al., 2010; Freeman, 1973; Che and Siu, 2010; Podunavac-Kuzmanovic and Cvetkovic, 2007) and an amino ... in mm and average zone inhibitions were determined Triplicate data were taken for the calculation of mean inhibition Results and discussion 15.3 lS cmÀ1 and 4b is 8.20 lS cmÀ1 while 4c and 4d ... sharp and strong vibrational frequency These bathochromic effects (ca 20 cmÀ1) in the groups were attributed to coordination See Fig The UV/visible spectra band assignment of the ligands and their...
Ngày tải lên: 02/09/2015, 13:46
Enhanced transdermal delivery with fatty acids and electroporation
... for CsA and for diseases such as psoriasis and atopic dermatitis, topical CsA has displayed superior efficacy and reduced side effects (Hewitt and Black, 1996) However, like most peptides and proteins, ... stretching vibrations give rise to bands in the spectral region 3100-2800 cm-1 and the strongest bands in the spectra of lipids correspond with the CH2 asymmetric (νa(CH2)) and symmetric (νs(CH2)) stretching ... be a useful tool in understanding the conformation of the SC lipids and proteins by looking at the shift in wavenumber frequencies and the intensity of absorption bands 2.7 Transdermal Delivery...
Ngày tải lên: 12/09/2015, 10:37
AN0559 optimizing serial bus operations with proper write cycle times
... for its worldwide headquarters, design and wafer fabrication facilities in Chandler and Tempe, Arizona in July 1999 The Company’s quality system processes and procedures are QS-9000 compliant for ... used in systems for two purposes: storing data and reading back data Read operations are at full clock speed, so the only methods for optimization are to run the clock at maximum frequency and to ... KEELOQ® code hopping devices, Serial EEPROMs and microperipheral products In addition, Microchip’s quality system for the design and manufacture of development systems is ISO 9001 certified 2002 Microchip...
Ngày tải lên: 11/01/2016, 11:51
The Transformation of Escherichia coli with Deoxyribonucleic Acid isolated from Bacteriophage Adgt
... active molecules carry dg, c, and mi Assuming that the entire dg region, as mapped by Arber (1958), is present, and that the segments between dg and c, and between c and mi are also present, this ... this phage suspension and freshly distilled phenol saturated with water at °C were mixed and agitated by hand for m in The two phaaes were separated by centrifugation and the aqueous phase recovered ... CsCI-3) and of Mg DNA at pH The phage were suspended in 0·01 M-MgSO and 0·01 M-potassiurn phosphate buffer and no correction was made for scattered light The DNA was dissolved in 0·15 M-NaCI and...
Ngày tải lên: 28/05/2016, 11:25
Tài liệu Báo cáo khoa học: Helicobacter pylori acidic stress response factor HP1286 is a YceI homolog with new binding specificity pdf
... HP1286 b-Strands, a-helices and turns are in yellow, red and green, respectively Strands are labeled from A to H Strands B and F, owing to some irregularities, are divided into two parts and labeled ... composed of two parts This happens for strands bB and bF, and, in fact, they have been labeled bB1 and bB2, and bF1 and bF2, respectively Two hundred and two hydrogen bonds among protein atoms stabilize ... strands Some of the strands present some kinks that break the continuity of the hydrogen bond patterns, and so they are formally considered to be composed of two parts This happens for strands...
Ngày tải lên: 16/02/2014, 14:20
Tài liệu Báo cáo khoa học: Suppressed catalytic efficiency of plasmin in the presence of long-chain fatty acids Identification of kinetic parameters from continuous enzymatic assay with Monte Carlo simulation ppt
... substrates Materials and methods Materials Sodium salt and free acid forms of oleic, stearic and arachidonic acids were purchased from Sigma-Aldrich Kft (Budapest, Hungary) and stock solutions ... mean (symbols) and standard deviation (cross-lines) of four measurements Lines represent best global fit of the data set to the equation of Model I described in the Materials and methods The ... limit below the estimated Km value and upper limit at least 5-fold higher than the Km estimate) The final best estimates of the catalytic constant (kp) and the Km, and their confidence intervals, are...
Ngày tải lên: 18/02/2014, 17:20
Tài liệu Báo cáo khoa học: Crystal structure of Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase complexed with an analogue of 1,3-bisphospho-D-glyceric acid Selective inhibition by structure-based design docx
... chain and all atoms of the 359 residues from ˚ ˚ each monomer are, respectively, 43.5 A2 and 43.8 A2 in ˚ ˚ ˚ monomer A, 46.8 A2 and 47.1 A2 in monomer B, 51.6 A2 ˚ in monomer C, and 43.2 A2 and ... for surface loops comprising residues 65–74, 99–103 and 117–121 in monomer C and 99–102 in monomer B and several residues at the N-terminus and C-terminus, which are poorly resolved The stereochemistry ... (GAP and 1,3-BPGA) and were completely nonselective as they inhibited the trypanosome and mammalian (rabbit muscle GAPDH) enzymes equally well [30] Secondly, the 2-oxo-diphosphonopentanes 5, 6, and...
Ngày tải lên: 20/02/2014, 02:21