expression of amp alpha 2 3 linked sia
biochemical and functional characterization of spda a 2 3 cyclic nucleotide phosphodiesterase from sinorhizobium meliloti
... cyclic AMP via TolC J Bacteriol 20 11, 1 93( 5):1086–1089 37 Jackson EK, Ren J, Mi Z: Extracellular 2? ?? ,3? ??-cAMP is a source of adenosine J Biol Chem 20 09, 28 4(48) :33 097? ?33 106 Page 12 of 12 38 Vallenet ... Biol Chem 20 08, 28 3( 45) :30 9 42? ? ?30 949 32 Kimura Y, Okazaki N, Takegawa K: Enzymatic characteristics of two novel Myxococcus xanthus enzymes, PdeA and PdeB, displaying 3? ??,5′- and 2? ?? ,3? ??-cAMP phosphodiesterase, ... Biol Chem 20 09, 28 4(47): 32 8 46– 32 8 57 25 Marx CJ, Lidstrom ME: Broad-host-range cre-lox system for antibiotic marker recycling in gram-negative bacteria Biotechniques 20 02, 33 (5):10 62? ??1067 26 Trülzsch...
Ngày tải lên: 01/11/2022, 08:49
Unit 2: The date of birth(A1,2,3)
... today? It’s October 10th 20 08 February 20 08 july 20 08 october 10 20 08 november 20 20 08 Matching (Ex WB pages 23 ) a- 1st b- 2nd 1- sixth 2- ninth c- 3rd d- 4th 3- seventh 4- first e- ... numbers first 1st second 2nd third 3rd fourth 4th fifth 5th sixth 6th seventh 7th eighth 8th twentieth 20 th twenty-first 21 st twenty-second 22 nd thirtieth 30 th What’s the ... 5- tenth 6- fifth 7- eighth 8- second a-4 b-8 c-10 d-9 e-6 f-1 g -3 h-7 i -2 j-5 Homework Do exrcise ( 12) THE END Warm up: Months of the year January February March April May June July August September...
Ngày tải lên: 29/09/2013, 10:10
Tài liệu CAMBRIGDE INTERNATIONAL DICTIONARY OF IDIOMS_ CHƯƠNG 2.3 pdf
... newspapers grab a grab bag American & Australian a mixture of different types of things • (often + of) Airlines are offering a grab bag of discounts, air miles and car rentals to attract customers ... 1 52 gaff programme ensures that we're ahead of the game stay ahead of the game· Staying ahead of the game in these days of rapid technological advancements is ... the championship hard/hot on the heeis of sth X if something comes hard on the heels of something else, it happens very soon after it • A film contract came hard on the heels of the success of their...
Ngày tải lên: 17/01/2014, 06:20
Tài liệu Báo cáo khoa học: Hypoxia reduces the expression of heme oxygenase-2 in various types of human cell lines A possible strategy for the maintenance of intracellular heme level pdf
... expression of heme oxygenase -2 20 21 22 23 24 25 26 27 28 29 30 31 Y Zhang et al explants and immortalized trophoblast cells Am J Physiol Heart Circ Physiol 28 4, H8 53? ??H858 Poss KD, Thomas MJ, Ebralidze ... (20 03) Effects of hypoxia on heme oxygenase expression in human chorionic villi FEBS Journal 27 3 (20 06) 31 36? ?31 47 ª 20 06 The Authors Journal compilation ª 20 06 FEBS 31 45 Reduced expression of ... by about 20 % in YN-1 cells after FEBS Journal 27 3 (20 06) 31 36? ?31 47 ª 20 06 The Authors Journal compilation ª 20 06 FEBS 31 37 Reduced expression of heme oxygenase -2 Y Zhang et al 48 h of hypoxia...
Ngày tải lên: 19/02/2014, 06:20
Báo cáo khoa học: Functional expression of the quinoline 2-oxidoreductase genes (qorMSL) in Pseudomonas putida KT2440 pUF1 and in P. putida 86-1 Dqor pUF1 and analysis of the Qor proteins doc
... Germany. (Received 20 November 20 02, revised 3 February 20 03, accepted 19 February 20 03) Eur. J. Biochem. 27 0, 1567–1577 (20 03) Ó FEBS 20 03 doi:10.1046/j.14 32 - 1 033 .20 03. 03 526 .x The genes encoding Qor have ... Biol. Chem. 27 2, 33 55? ?33 62. 28 . Temple, C.A., Graf, T.N. & Rajagopalan, K.V. (20 00) Optimi- zation of expression of human sulfite oxidase and its molybdenum domain. Arch. Biochem. Biophys. 38 3, 28 1? ?28 7. 29 . ... Yield (%) Crude extract 3 12 30 45 0.10 1 100 Ammonium sulfate ppt 27 1 416 0.65 6.4 87 Phenyl Sepharose CL-4B 29 9 78 3. 83 37.5 96 BioScale DEAE10 20 6 9 .3 22 .1 21 6.7 66 15 72 U. Frerichs-Deeken et...
Ngày tải lên: 17/03/2014, 10:20
báo cáo khoa học: "ShRNA-mediated gene silencing of MTA1 influenced on protein expression of ER alpha, MMP-9, CyclinD1 and invasiveness, proliferation in breast cancer cell lines MDA-MB-231 and MCF-7 in vitro" pptx
... PG group and PGM2 group were 35 . 43 ± 1. 52% , 34 .88 ± 2. 12% , 32 . 95 ± 2. 29%, there were no statistically significant difference(P > 0.05) The results indicated that, more MDA-MB - 23 1 cells were blocked ... cancers[J] Cancer Sci 20 06, 97(5) :37 4-79 Ikeda K, Inoue S: Estrogen receptors and their downstream targets in cancer [J] Arch Histol Cytol 20 04, 67(5): 435 - 42 20 21 22 23 Lin CY, Ström A, Vega ... Biol Chem 20 00, 27 5 (31 ) : 23 4 62- 70 Yao YL, Yang WM: The metastasis-associated proteins and form distinct protein complexes with histone deacetylase activity [J] J Biol Chem 20 03, 27 8( 43) : 425 60-68...
Ngày tải lên: 10/08/2014, 10:21
![Pentafluorophenylammonium triflate (PFPAT) catalyzed facile construction of substituted chromeno[2,3-d]pyrimidinone derivatives and their antimicrobial activity](https://media.store123doc.com/images/document/2020_01/13/medium_wyg1578862473.jpg)
Pentafluorophenylammonium triflate (PFPAT) catalyzed facile construction of substituted chromeno[2,3-d]pyrimidinone derivatives and their antimicrobial activity
... 6 .25 (16–14) 6 .25 (30 ? ?34 ) 12. 5 (20 ? ?22 ) 6 .25 (20 ? ?22 ) 12. 5 (20 ? ?22 ) 12. 5(16–18) 6 .25 (16–18) 6 .25 ( 12? ??15) 25 (10– 12) 25 (10– 12) 6 .25 (18? ?22 ) 6 .25 (16–18) 6 .25 (27 ? ?30 ) 12. 5 (20 ? ?22 ) 6 .25 (18? ?20 ) 12. 5(18? ?20 ) 12. 5(18–18) ... 12. 5(10– 12) 6 .25 ( 12? ??16) 6 .25 (10–14) 25 (10– 12) 25 (10– 12) 6 .25 (15–16) 6 .25 (14–18) 6 .25 (22 ? ?26 ) 12. 5(18? ?22 ) 6 .25 (18? ?22 ) 12. 5(18? ?22 ) 12. 5( 12? ??16) 6 .25 ( 12? ??16) 6 .25 ( 12? ??14) 25 (8–11) 25 (9– 12) 6 .25 (18? ?22 ) ... cmÀ1): 34 13, 33 42, 32 1 4, 22 17, 16 62, 1 638 , 1484, 120 3, 785; 1H NMR (500 MHz, CDCl3) d: 1 .20 (t, J = 7 .2 Hz, 3H, CH3CH2), 2. 66 (s, 6H, N(CH3 )2) , 2. 28 (s, 3H, CH3), 4.11 (q, J = 7 .2 Hz, 2H, CH3CH2),...
Ngày tải lên: 13/01/2020, 03:54
Synthesis and antibacterial activity of new 1,2,3-triazolylmethyl- 2H-1,4- benzothia zin-3(4H)-one derivatives
... – 62. 5 25 0 31 .25 25 0 25 0 25 0 125 125 – – 25 0 – – 125 – 25 0 – – 25 0 – – 125 25 0 25 0 – – 25 0 – – 7a – – – 25 0 125 62. 5 – 62. 5 7b 125 – – 125 62. 5 62. 5 – 62. 5 8a 62. 5 62. 5 – 125 125 62. 5 – 125 8b ... 129 .51, 129 .09, 127 .90, 126 .66, 124 .27 , 1 23 .54, 117.97 (CHarom), 84 .33 , 73. 80, 72. 58, 70.58, 67.99 (5CH, C 1, C2, C3, C4, C5), 62. 28 (CH2–O), 41.51 (CH2–N), 20 .96, 20 . 82, 20 .68, 20 .26 ... (d, 2H, C H2–N); 13C-NMR (DMSO-d6, 62. 5 MHz); 160.79 (CO), 136 .01, 134 .48, 133 .51, 121 .18, 118. 42 (Cq), 134 .28 (CHvinyl), 128 .40 (CHtriazole), 134 .28 , 1 32 . 55, 129 . 12, 128 .40, 126 .95, 124 . 73, ...
Ngày tải lên: 29/05/2020, 13:26
Elevated expression of hyaluronan synthase 2 associates with decreased survival in diffusely infiltrating astrocytomas
... 20 (80.0%) (16.7%) 66 (55.5%) 87 (58.0%) Female (20 .0%) ( 83. 3%) 53 (44.5%) 63 ( 42. 0%) Gender Mean age at time of diagnosis (years) 40.6 46 .2 58 .3 54.8 Mean survival time (months) 36 .5 29 .5 13. 4 ... = 0.044, Fig 4e) 53% ( 52/ 98) of grade IV tumors, 33 % (2/ 6) of grade III tumors and 21 % (4/19) of grade II tumors had moderate staining intensity In other words, 72% (18 /25 ) of grade II-III tumors ... Sci 20 04;117(Pt 2) :35 9–67 29 Cook AC, Chambers AF, Turley EA, Tuck AB Osteopontin induction of hyaluronan synthase expression promotes breast cancer malignancy J Biol Chem 20 06 ;28 1 (34 ) :24 38 1–9 30 ...
Ngày tải lên: 24/07/2020, 01:36
Prognostic significance of the expression of GFRα1, GFRα3 and Syndecan-3, proteins binding ARTEMIN, in mammary carcinoma
... (37 .0) 26 (28 .3) 24 (26 .1) > 55 51 17 (33 .3) 15 (29 .4) 16 (31 .4) Tumor size (cm) ? ?2 13 2~ 5 115 38 (33 .0) 33 (28 .7) 30 (26 .1) >5 31 13 (41.9) 10 ( 32 . 3) (46 .2) 0. 135 16 (51.6) (30 .8) 0 .37 (38 .5) 0.555 ... ( 32 . 3) PR status^^ 0.517 28 (31 .1) 22 (31 .9) 0.917 22 (24 .4) 0 .21 8 23 (33 .3) HER -2 * - 121 40 (33 .1) + 38 20 ( 52. 6) 0. 03 31 (25 .6) 0.005 33 (27 .3) 0.607 19 (50.0) 12 (31 .6) ^ ER positive required ... 94 39 (41.5) + 65 21 ( 32 . 3) - 90 32 (35 .6) + 69 28 (40.6) Grade 0.657 (30 .8) 0.906 (30 .8) 0.788 Stage 31 (41.9) 22 (29 .7) ER status^ 0 .24 27 (28 .7) 0 .37 4 23 (35 .4) 24 (25 .5) 0 .35 1 21 ( 32 . 3) PR...
Ngày tải lên: 05/11/2020, 07:02
unit 13 unit 13 films and cinema lesson speaking task 1 matching look at the pictures find out what kinds of film 1 2 3 6 5 4 a b 7 8 c cartoon a thriller b detective film d action film e war film h
... (1)Unit 13: FILMS AND CINEMA (2) Task 1: Matching Look at the pictures (3) (4)1 2 3 6 5 4 A B 7 8 c cartoon a thriller b detective film ... love story film g horror film f science fiction film Match the pictures in column A with (5)1 2 3 6 5 4 A B 7 8 cartoon thriller detective film war film love story film horror film c cartoon ... kỳ (7)(8)A: What you think of? ??…… ?horror films B: Oh, I find them really………terrifying C: I don’t quite agree with you I find them very……… interestingadj adj Example: I find horror films...
Ngày tải lên: 27/04/2021, 05:04
NN AN ANALYSIS OF a SUGGESTED TRANSLATION OF CHAPTERS 1, 2 3 FROM THE BOOK “LIVING IN THE LIGHT a GUIDE TO PERSONAL TRANSFORMATION” BY SHATKI GAWAIN AND LAUREL KING, 1998
... 2. 2.1.5 Idiom 2. 2.1.6 Style and Clarity 2. 2 .2 Methods of Translation 2. 2 .2. 1 Word-for-word Translation 2. 2 .2. 2 Literal Translation 2. 2 .2. 3 ... Translation 2. 2 .2. 4 Semantic Translation 2. 2 .2. 5 Adaptation 10 2. 2 .2. 6 Idiomatic Translation 10 2. 2 .2. 7 Communicative Translation 10 2. 2 .2. 8 Free translation ... 2. 1.1 Definition of Translation 2. 1 .2 Types of Categories 2. 1 .2. 1 Full vs Partial Translation 2. 1 .2. 2 Total vs Restricted Translation 2. 1 .2. 3 Phonological...
Ngày tải lên: 29/03/2022, 12:50
Báo cáo khoa học:" The interaction between the measles virus nucleoprotein and the Interferon Regulator Factor 3 relies on a specific cellular environment" pdf
... +IRF3 NTAIL L496C NTAIL V517C 34 7 34 8 34 9 35 0 35 1 3 52 35 3 35 4 35 5 35 6 34 7 34 8 34 9 35 0 35 1 3 52 35 3 35 4 35 5 35 6 B (mT) B (mT) Analysis of Figure NTAIL structural transitions in the presence of IRF -3 ... Virology Journal 20 09, 6:59 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 Tompa P: Intrinsically unstructured proteins Trends Biochem Sci 20 02, 27 : 527 - 533 Uversky VN: Natively ... mechanism of http://www.virologyj.com/content/6/1/59 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 autoinhibition and virus-induced phosphoactivation Nat Struct Biol 20 03, 10:9 13- 921 ...
Ngày tải lên: 12/08/2014, 04:21
Tài liệu Báo cáo Y học: Study of substrate specificity of human aromatase by site directed mutagenesis pdf
... ± 24 73 ± 21 27 ± NC2 NC2 23 88 ± NC2 ND 24 43 ± NC3 4107 ± ± ± ± ± ± ± 30 51 28 12 16a 41 ± 10 104a 176 ± 63 25 1c 38 6 ± 1 52 1461 30 1b 6 23 30 2a 1465 7 82 106 159 133 49 81 69 ± ± ± ± ± ± 48 20 48 25 ... NC2 NC2 68 ± NC2 ND 29 0 ± NC3 635 ± 38 100 ± 23 824 100 ± 27 71 50 1 13 ± 43 76 ± 30 605a 657 56 ± 19 87 ± 21 51a 84 7a 47 20 a 28 7 109 34 91 89 67 30 41 ± NC1 NC1 NC1 NC1 NC2 1 727 ± 26 71 ± NC1 32 4 0 ... D476E 23 8 ± 25 6 ± 76 ± ND NC1 NC1 NC2 480 ± NC3 45 93 ± 1508 ± 1610 ± ND NC1 NC1 NC2 26 61 ± NC3 35 8 ± – 791 ± ND 30 1 ± 38 6 ± 33 8 ± 414 ± NC3 4 531 ± – 835 ± ND 46 62 ± 21 65 ± 34 94 ± 38 50 ± NC3 a 19 29 ...
Ngày tải lên: 21/02/2014, 15:20
Báo cáo khoa học: Characterization of HbpR binding by site-directed mutagenesis of its DNA-binding site and by deletion of the effector domain pot
... medium [5.5 gÆL)1 of Mops free acid, 5.1 gÆL)1 of Mops sodium salt, 0.5 gÆL)1 of NaCl, gÆL)1 of NH4Cl, 0.06 gÆL)1 of Na2HPO4Æ2H2O, 0.05 gÆL)1 of KH2PO4, mm MgSO4, 0.1 mm CaCl2, 0 .2% (w ⁄ v) glucose, ... site of the aromatic-responsive r54-dependent regulator DmpR J Biol Chem 27 4, 32 4 25– 32 4 32 16 Garmendia J & de Lorenzo V (20 00) Visualization of DNA–protein intermediates during activation of the ... Degradation of 2- hydroxybiphenyl and 2, 2¢-dihydroxybiphenyl by Pseudomonas sp strain HBP1 Appl Environ Microbiol 54, 26 83 26 88 Kohler H-PE, Schmid A & van der Maarel M (19 93) Metabolism of 2, 2¢-dihydroxybiphenyl...
Ngày tải lên: 07/03/2014, 17:20
Báo cáo khoa học: Probing the catalytic potential of the hamster arylamine N-acetyltransferase 2 catalytic triad by site-directed mutagenesis of the proximal conserved residue, Tyr190 pot
... 8.14 17 2. 23 60 106 30 15 13 1700 136 0 974 29 20 0 22 6 37 7 11 pKa = 5 .34 PNPA PABA H2 N COOH pKa = 4.67 PNPA pABglu O COOH H2N pKa = 2. 93 HN CH2CH2COOH AcCoA PNA H2N NO2 pKa = AcCoA ... 620 39 3 60 38 40 29 62 51 13 10 27 00 1786 746 34 5 400 21 4 146 46 Wild-typea Y190F Y190I Y190A 1.5 2. 8 11 5.6 0.1 0 .2 0.6 1.7 2. 5 2. 7 6 .2 0.1 0 .2 0 .2 0.6 120 86 77 16 3 ... & Wilkie TR 6940 29 30 31 32 33 34 35 36 37 38 39 40 41 Sr (1997) Rodent models of the human acetylation polymorphism: comparisons of recombinant acetyltransferases Mutat Res 37 6, 101106 Vatsis...
Ngày tải lên: 16/03/2014, 00:20
Báo cáo khoa học: Functional significance of five noncanonical Ca2+-binding sites of human transglutaminase 2 characterized by site-directed mutagenesis potx
... sites of TG2 ´ly R Kira et al 27 28 29 30 31 32 33 34 35 36 36 a 37 38 domains of the autoantigen tissue transglutaminase Clin Exp Immunol 125 , 21 6 22 1 Roth EB, Sjoberg K & Stenberg P (20 03) Biochemical ... –10 190 S5 W S2A 20 0 S4 21 0 22 0 23 0 Wavelength (nm) Fig CD spectra of recombinant TG2 proteins 24 0 25 0 As the transglutaminase activity of TG2 is Ca2+dependent, decreased activity of the mutants ... (DAbs·min·mg–1) Mutants WT S1 S2A S2B S3A S3B S4 S5 0 10 20 30 40 [Ca2+] (mM) 120 Filter paper method Microtiter plate method 100 120 D 80 60 40 20 GTP µM/Ca2+ mM GTP 100 µM/Ca2+ mM P = 0.0 135 100 Relative...
Ngày tải lên: 16/03/2014, 03:20
Báo cáo khoa học: Residues affecting the chloride regulation and substrate selectivity of the angiotensin-converting enzymes (ACE and ACE2) identified by site-directed mutagenesis pot
... R186QR489QR 522 Q 16.67 7.14 3. 79 7. 13 3. 62 2. 72 100.0 42. 8 22 .7 42. 8 21 .7 16 .3 Wild-type R169Q W271A K481Q R514Q R169QK481QR514Q 1.98 0.10 0.10 0. 42 1. 03 1.05 100.0 5 .2 5 .3 21 .0 52. 0 53 .2 ± ± ± ± ... ª 20 08 The Authors Journal compilation ª 20 08 FEBS CL1 site A tACE variants W279 /27 1 R489/K481 R 522 Q R489Q W279A R186Q WT Q281/R2 73 Mock A Chloride regulation of ACE and ACE2 R186QR489QR 522 Q ... Journal 27 5 (20 08) 6 033 –60 42 ª 20 08 The Authors Journal compilation ª 20 08 FEBS 6 037 Chloride regulation of ACE and ACE2 A Fig Activity of tACE and ACE2 variants in the absence and presence of NaCl...
Ngày tải lên: 16/03/2014, 04:20
Báo cáo khoa học: Probing the unfolding region of ribonuclease A by site-directed mutagenesis potx
... A20P S21P S21L A20P/S21P N34D L35A L35S F46Y K31A/R33S L35A/F46Y L35S/F46Y K31A/R33S/F46Y 3. 9 2. 4 3. 5 2. 5 2. 8 2. 9 3. 1 0.9 1.8 1 .2 0.8 0.8 1 .2 2.79 2. 89 2. 90 2. 78 2. 82 2.86 1. 93 1.84 1.88 1. 92 1.59 ... unfolded state of the protein Residue Relative accessibility (%) Met29 Met30 Lys31 Ser 32 Arg 33 Asn34 Leu35 Thr36 Lys37 Asp38 Arg39 Cys40 Lys41 18 76 66 23 48 12 60 68 69 11 21 Pro 42 Val 43 Asn44 Thr45 ... 1.59 1.51 1.64 0.7 0.4 0 .3 0 .2 0.4 0.1 0 .3 0 .2 0.1 0 .2 0.1 0 .2 0 .3 0. 03 0. 03 0. 02 0. 02 0. 02 0. 02 0. 02 0. 02 0. 02 0. 02 0.01 0. 02 0. 02 1.0 f N 0.5 0.0 mDG (kJặmol)1ặM)1)...
Ngày tải lên: 16/03/2014, 18:20
Báo cáo khoa học: Mapping of the active site of glutamate carboxypeptidase II by site-directed mutagenesis potx
... compilation ª 20 07 FEBS ˇ ´ P Mlcochova et al 25 26 27 28 29 30 31 32 33 34 an aminopeptidase domain: implications for drug design Protein Sci 8, 25 46 25 49 Barinka C, Mlcochova P, Sacha P, Hilgert ... consisted of side chains of Arg210, Asn257, His377, Asp387, Glu 424 , Glu 425 , Asp4 53, Asn519, Tyr5 52, His5 53, Lys699, Tyr700, two zinc(II) ions including the bridging H2O ⁄ OH– moiety and the molecule of ... c-carboxyl4 734 Km (lM) kcat (s)1) Wild-type a,c 1.15 ± 0.57 1.1 ± 0 .2 Residues in the S1¢ substrate binding site R210Aa,b 29 4 ± 15 0. 0 23 ± 0.001 R210Ka,b 801 ± 124 0. 130 ± 0. 020 N257Da,b 68.10 ± 19.7 0. 32 0 ...
Ngày tải lên: 23/03/2014, 07:20