expression assay and functional properties of rilp
Báo cáo y học: "Expression and functional properties of antibodies to tissue inhibitors of metalloproteinases (TIMPs) in rheumatoid arthritis" docx
... activation Several functional properties of TIMPs are of potential importance in the pathogenesis of arthritis Overexpression of TIMP-1 and TIMP-2 is associated with inhibition of apoptosis and invasive ... laboratory, and statistical evaluation of material from RA patients; and preparation of the manuscript LD performed the collection and clinical analysis of patients with degenerative joint diseases and ... revision of the manuscript AT contributed to the conception of the study and study design, statistical evaluation of the results, and preparation of the manuscript All authors read and approved...
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Tài liệu Báo cáo khoa học: Interleukin-1-inducible MCPIP protein has structural and functional properties of RNase and participates in degradation of IL-1b mRNA doc
... LPS, TNFa and phorbol 12-myristate-13-acetate (PMA) Moreover, we found that MCPIP has RNase properties and regulates the half-life of IL-1b mRNA and its own transcript Overexpression of MCPIP ... mRNA and also of its own transcript For this reason, the level of mRNA for the wildtype form of MCPIP and the level of mRNA for IL-1b (Fig 5A, lane 3) were lower in comparison to the level of mRNA ... heart and placenta, and the lowest levels in spleen, kidney, liver and lung The transcript was not detectable in brain, thymus, muscles, small intestine and colon (Fig 3A) The high expression of...
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Báo cáo khoa học: Quaternary structure and functional properties of Penaeus monodon hemocyanin docx
... oxygen-binding properties The ultimate aim is a precise definition of the allosteric unit responsible for cooperativity and of the possible role of heterogeneity at subunit level in the modulation of the functional ... allosteric properties of the protein and to trace the evolutionary pathway of the allosteric behaviour Results Characterization of the oligomeric state of P monodon Hc In gel-filtration experiments of ... structural stability of arthropod Hc oligomers, the reversibility of the dissociation processes and the occurrence of different subunits, in order to correlate the structural properties of the various...
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Báo cáo y học: "Genotypic and functional properties of early infant HIV-1 envelop" doc
... between maternal and infant clones The V3 loop charge and glycosylation are predictive of co-receptor tropism [19,20] Examination of charge and glycosylation of the V3 loops of our env clones ... 88% of env clones proved functional, with no significant differences in functionality between mothers and infants detected within or across transmission pairs (data not shown) A total of 162 functional ... Sensitivity of envelope clones to neutralization by monoclonal antibodies and pooled seropositive plasma Using a standardized assay [22,23], we tested the neutralization sensitivity profile of our...
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Báo cáo y học: "Analysis of proteomic profiles and functional properties of human peripheral blood myeloid dendritic cells, monocyte-derived dendritic cells and the dendritic cell-like KG-1 cells reveals distinct characteristic" doc
... presence of × 104 irradiated (3,000 rad 137Cs) immature mDCs and interactions Figure Cytokine expression profiles of cells Cytokine expression profiles of cells Cytokine production by mDCs and the ... functions The functional relevance of differentially expressed proteins was confirmed by analysis of surface marker expression, cytokine profile, endocytic and T cell activation abilities of the cells, ... mDCs and moDCs [12] and moDCs and KG-1 cells [13], but no studies have compared the proteomes of all three cell types In this study we compare the proteomes of mDCs, moDCs and KG-1 cells, and...
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Expression analysis and functional significance of chondroitin sulphate proteoglycans and heparan sulphate proteoglycans in prostrate cancer
... addition of GlcA and GlcNAc N-deacetylation and N-sulphation of GlcNAc units N-deacetylation and N-sulphation of GlcNAc units N-deacetylation and N-sulphation of GlcNAc units N-deacetylation and N-sulphation ... processes? 3.8.5 Aberrant expression of GAGs and PGs genes in prostate 100 cancer 3.8.6 Conclusions 106 Page | vi Table of contents Chapter Expression and Functional Analysis of Chondroitin 107 ... Table of contents Chapter Expression and Functional Analysis of Heparan Sulphate 189 in Prostate Cancer 5.1 5.1.1 Expression analysis of heparan sulphate in prostate cancer 189 Localization of...
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Novel biochemical and functional properties of the HPV 16 oncoprotein e6
... (PART 1): BIOPHYSICAL PROPERTIES OF E6 AND E7 33 3.1 Biophysical properties of the E6 and E7 proteins: Previous data and concept of this study 33 3.2 Biophysical properties of the E7 protein: ... including E2F-mediated aberrant expression of the cyclins E and A (Hickman, Picksley, and Vousden, 1994) and cdc25A (Katich, Zerfass-Thome, and Hoffmann, 2001), inactivation of the p53-responsive CKI ... properties of E6 and E7 3.1 Biophysical properties of the E6 and E7 proteins: Previous data and concept of this study To determine the biophysical properties of proteins and, ultimately, determine their...
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EXPRESSION ANALYSIS AND FUNCTIONAL STUDY OF HS3ST3B1 IN HUMAN PROSTATE CANCER
... to offer his support and advice I would also like to thank Professor Bay Boon Huat and Associate Professor Tay Sam Wah, Samuel for their timely encouragement and advice Professor Bay and Professor ... Table of contents iii Summary ix List of Tables xi List of Figures xiii List of Abbreviations xv Chapter Introduction 1.1 Prostate gland and prostate cancer 1.1.1 The anatomy of the prostate gland ... Histopathology of the Prostate Gland 1.1.4.1 Normal histology of the prostate Columnar secretory cells line the ducts and acini of the prostate gland These ducts and acini are regularly spaced and are...
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Báo cáo khoa học: Molecular cloning, expression analysis and functional confirmation of ecdysone receptor and ultraspiracle from the Colorado potato beetle Leptinotarsa decemlineata pdf
... of primary amino acid structures of EcR and USP from L decemlineata (b) the analysis of mRNA expression profile of L decemlineata, EcR and USP, and (c) the measurement of the binding affinity of ... 6.29 and L migratoria USP showed higher homology to RXR of human and mouse than USP isoforms of dipteran and lepidopteran insects Thus, the functions of USP of L decemlineata, T molitor and L ... staining of rRNA is shown as a control for equal loading (B) The expression of LdEcR-A and LdEcR-B1 mRNA in integument of last instar larvae Temporal expression profiles were studied using isoform-specific...
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Báo cáo khoa học: Sulfation of hydroxychlorobiphenyls Molecular cloning, expression, and functional characterization of zebrafish SULT1 sulfotransferases docx
... Detection of zebrafish SULT1 ST1 and ST2 mRNAs and (B) Western blot analysis of zebrafish SULT1 ST1 protein (A) Detection of zebrafish SULT1 ST1 and ST2 mRNAs in cultured zebrafish cells (lanes and 3) and ... dose-dependence of the regulation of the activity of the zebrafish ST by these divalent metal cations and their modes of action Fig Effects of divalent metal cations on the sulfating activity of the zebrafish ... (H-chain; Mr ¼ 200 000) Fig pH-dependency of the 2-naphthol-sulfating activity of purified zebrafish SULT1 STs1 and The enzymatic assays were carried out under standard assay conditions as described using...
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Báo cáo khoa học: Comparison of functional properties of two fungal antifreeze proteins from Antarctomyces psychrotrophicus and Typhula ishikariensis ppt
... producing AFPs In this study we performed assays of antifreeze activity against culture media of a total of 23 species of ascomycetes, and identified and purified AFP from an ascomycete collected ... both AFPs had relatively low contents of Arg (1.3% and 0.9%), Met (0.8% and 0.9%) and Tyr (1.9% and 2.4%) Another significant feature of AnpAFP is the presence of 2% Cys; however, Cys was not detected ... indicative of the binding of these hyperactive AFPs to both pyramidal and basal planes of a seed hexagonal ice crystal Comparison of TH activity between AnpAFP and TisAFP8 Figure 5A shows the results of...
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Báo cáo khoa học: Expression and functional characterization of P2Y1 and P2Y12 nucleotide receptors in long-term serum-deprived glioma C6 cells ppt
... proliferative and differentiation state, basal level of ERK1 ⁄ and Akt kinase phosphorylation, and P2Y1 and P2Y12 receptor protein expression and functional activity Examination of the effects of specific ... characterized by increased expression of the P2Y12 receptor and low expression of the P2Y1 receptor In cells grown in medium containing 10% (v ⁄ v) fetal bovine serum, the expression ratio of the two receptors ... ⁄ G1, 25% in G2 ⁄ M, and 15% in S phase After 24 and 48 h of serum starvation, 80% and 90% of cells were growth arrested, respectively However, there were still a number of unsynchronized cells,...
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Báo cáo y học: "Chemokine receptor expression and functional effects of chemokines on B cells: implication in the pathogenesis of rheumatoid arthritis" ppt
... cellular proliferation and expression of cytokines and activation markers by peripheral blood T cells [36,37], and that CCL2, CCL5 and CXCL12 upregulated the expression of cytokines and chemokines by ... peripheral B cells of both normals and subjects with RA, and CXCL12 enhanced the expression of ICOSL on both normal and RA B cells In contrast, the effect of CCL20, CCL19 and CCL21 was not significant ... CD19, CD27, and CCR5, CCR6, CCR7, CXCR3, CXCR4 or CXCR5, and the expression of the various markers was analyzed by flow cytometry CD19+ B cells were gated, and the frequency of expression of each...
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báo cáo khoa học: "Gene family structure, expression and functional analysis of HD-Zip III genes in angiosperm and gymnosperm forest trees" pps
... bundles, and altered leaf, stem and carpel organ abaxial, adaxial pattern polarity Overexpression of the Z elegans ZeHB-12, a homologue of REV, led to an increased number of xylem precursor cells and ... This small family of regulators are known for their overlapping expression profiles and their functional redundancy The aim of this study was to develop insights into the role of HD-Zip III genes ... Cross-sections of mature petiole (40×, LP 21), observed under UV-illumination to reveal autofluorescence of lignified cell walls of fibre and vessel elements (C) Distribution of fibre lengths...
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Báo cáo y học: "Natural selection of protein structural and functional properties: a single nucleotide polymorphism perspect" potx
... [24] and investigated the correlation between selective constraints and four gene expression parameters examined previously: peak expression level, mean expression level, expression breadth, and ... alignments and protein alignment conservation We then obtained a variety of structural and functional properties from either database annotations or computational prediction methods and analyzed ... practice given the current volume of SNP data, and there have not been any large-scale studies of selective constraints on protein structural and functional properties using SNP data In the present...
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Báo cáo y học: "Consensus clustering and functional interpretation of gene-expression data" docx
... Output:Set of Robust Clusters RC Application of robust clustering Robust clustering was applied to both the ASC and B-cell lymphoma datasets and the partitioning of the gene -expression profiles observed ... of the first pair in List Then the pairs in List are iterated through and checked to see if one of the members of the current pair is within any of the existing clusters, RCi If one element of ... list of clusters (3) Create a cluster and insert the two ele ments (x, y) of the first pair in List into it (4) For i = to size of List-1 (5) For j = to number of Clusters in RC (6) If x or y of...
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Functional and structural properties of molecular soy protein fractions
... properties of food proteins: effects of reduction of disulfide bonds on film properties and foam stability of glycinin Journal of Food Science 1987, 56, 242-258 27) Kinsella, J E Functional properties ... Table 1.2 Functional properties of soy protein (Kinsella, 1979) Table 2.1 Hardness of soy gel heated for 60, 80 and 100 minutes Table 2.2 Comparision of L*, hardness and pH of various ratio of 7S:11S ... during the extraction of 11S caused the 11S to have higher level of isoflavone, better foaming properties and formed harder gels I The functional and structural properties of 2S soy protein in...
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Electronic and Optoelectronic Properties of Semiconductor Structures
... principles and actual devices Electronic and Optoelectronic Properties of Semiconductor Structures provides engineering and physics students and practitioners with complete and coherent coverage of key ... manual and set of viewgraphs for use in lectures is available for instructors received his Ph.D from the University of Chicago and is Professor of Electrical Engineering and Computer ... University of Michigan, Ann Arbor He has held visiting positions at the University of California, Santa Barbara and the University of Tokyo He is the author of over 250 technical papers and of seven...
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Tài liệu Báo cáo " The effect of cobalt substitution on structure and magnetic properties of nickel ferrite " pptx
... the compensation of ion Fe3+ in the tetrahedral and octahedral location That led to increasing of total magnetization of a molecule Ni1-xCoxFe2O4 and hence there is increasing of MS (table 3) ... several hundreds of gauss Thus, the increasing of Co-concentration led to the increasing of anisotropy property of ferrites Ni1-xCoxFe2O4, hence it was the increasing of HC The increasing of HC proved ... (511) and (440) These planes are indications of the presence of a spinel cubic structure The diffraction lines corresponding to a cubic, spinel-type and crystalline phase provides clear evidence of...
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Tài liệu Physical health and functional ability of an elderly, population in Sri, Lanka doc
... tests of physical performance for assessing the functioning of upper and lower extremities were carried out, using standard procedures These included: semi tandem stand, full tandem stand, rising ... 84% in Indonesia and 62% in Thailand (10) It was D N Fernando and R de A Seneviratna 14 Table Self-assessed "health status" by some psychosocial factors and indicators of use of health services ... American Journal of Public Health 1981; 71(11): 1211-1216 D N Fernando and R de A Seneviratna Fries J F Aging, natural death and the compression of morbidity Tlie New England Journal of Medicine 1980;...
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Tìm thêm: khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct mở máy động cơ lồng sóc các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25