experimental animal models for investigating renal cell carcinoma pathogenesis and preclinical therapeutic approac

báo cáo hóa học:" A brief symptom index for advanced renal cell carcinoma" pot

Ngày tải lên : 20/06/2014, 16:20

... distribution- and anchor-based analyses The standard deviations of baseline, week, and week index scores were divided by and to determine 1/3 and 1/2 standard deviation (SD) estimates for an MID ... study, performed the statistical analysis and interpretation of data, and drafted the manuscript DC participated in the design and conception of the study and helped revise the manuscript for important ... advanced renal cell carcinoma J Clin Oncol 1999, 17:2530-2540 Cohen J: Statistical Power Analysis for the Behavioral Sciences 2nd edition Hillsdale, NJ, Erlbaum; 1988 Center for Drug Evaluation and...

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The molecular epidemiology of renal cell carcinoma subtypes and prognosis

Ngày tải lên : 11/09/2015, 09:56

... values for the models and the trial criteria for the clea cell RCC e a ar dataset (A the UISS and the Leibov A) a vich models and (B) the co a orresponding trial criteria a adapted from ea model Models ... clinical models for outcome predictions in RCC, and the second being the evaluation of molecular models in RCC, and corresponding molecular insights For the first area, we focused on the clinical models ... plots for the Singapore data set 45 Figure 6: Predictive values for the models and the trial criteria for the clear cell RCC dataset 46 Figure 7: Comparison of the Kattan and Karakiewicz...

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Báo cáo sinh học: "Comparisons of three polyethyleneimine-derived nanoparticles as a gene therapy delivery system for renal cell carcinoma" doc

Ngày tải lên : 18/06/2014, 19:20

... at 95°C for min, and then 30 cycles at 94°C for 45 s, 54°C for min, 72°C for and a final extension cycle of 72°C for The house-keeping gene b-actin was taken as a loading control HEK293T cells ... performed the experiments and wrote the paper draft; LS conceived, instructed the experiments and revised the paper; SG and XX performed experiments and analyzed data; ZX and ZP collected and ... SEM (standard error of mean), and the statistics were performed with Student’s t test than their corresponding PEI precursor on OS-RC-2 tumor cells and on other cell types, including Ana-1 and HUVEC...

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báo cáo hóa học:" Comparisons of three polyethyleneimine-derived nanoparticles as a gene therapy delivery system for renal cell carcinoma" pot

Ngày tải lên : 20/06/2014, 03:20

... at 95°C for min, and then 30 cycles at 94°C for 45 s, 54°C for min, 72°C for and a final extension cycle of 72°C for The house-keeping gene b-actin was taken as a loading control HEK293T cells ... performed the experiments and wrote the paper draft; LS conceived, instructed the experiments and revised the paper; SG and XX performed experiments and analyzed data; ZX and ZP collected and ... SEM (standard error of mean), and the statistics were performed with Student’s t test than their corresponding PEI precursor on OS-RC-2 tumor cells and on other cell types, including Ana-1 and HUVEC...

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$Báo cáo khoa học: " Stereotactic body radiation therapy for melanoma and renal cell carcinoma: impact of single fraction equivalent dose on local control" ppt$

Báo cáo khoa học: " Stereotactic body radiation therapy for melanoma and renal cell carcinoma: impact of single fraction equivalent dose on local control" ppt

Ngày tải lên : 09/08/2014, 09:20

... single high dose SRS to brain and spinal metastases for both melanoma and RCC [8-10,26] In these studies the LC for melanoma is typically lower than for RCC [10,26], for which brain SRS can achieve ... metastatic renal cell carcinoma Int J Radiat Oncol Biol Phys 1985, 11:2007-2009 Halperin EC, Harisiadis L: The role of radiation therapy in the management of metastatic renal cell carcinoma Cancer ... radiation therapy for melanoma and renal cell carcinoma: impact of single fraction equivalent dose on local control Radiation Oncology 2011 6:34 Submit your next manuscript to BioMed Central and take...

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Báo cáo khoa hoc:" Retroperitoneoscopic radical nephrectomy with a small incision for renal cell carcinoma: Comparison with the conventional method" docx

Ngày tải lên : 11/08/2014, 07:21

... flank pad and to access the retroperitoneal space under one’s direct vision nephrectomy for renal cell carcinoma is T1N0M0 renal cell carcinoma That’s because we thought that laparoscopic approach ... partial nephrectomy for renal cell carcinoma soon after introducing it into their institution with the outcomes of an open laparoscopic partial nephrectomy for renal cell carcinoma, and reported that ... nephrectomy for renal cell carcinoma exhibits higher efficiency [6], and thus open partial nephrectomy or laparoscopic partial nephrectomy is more frequently performed in the treatment of T1a renal cell...

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Báo cáo khoa học: Expression of cholinesterases in human kidney and its variation in renal cell carcinoma types pdf

Ngày tải lên : 06/03/2014, 22:21

... Cholinesterases in renal carcinomas E Munoz-Delgado et al ˜ Introduction Renal cell carcinomas (RCCs), which account for 2% of adult malignancies, affect about 150 ... ducts of Bellini (1%), and Xp11 translocation RCC and unclassiﬁed RCC (together 1%) Benign or less severe tumours are papillary renal cell adenoma, metanephric adenoma, and renal oncocytoma (RO) ... Table Acetylcholinesterase and butyrylcholinesterase activities in noncancerous kidney (Control) and renal cell carcinoma (Tumour) Activities are given as mean ± standard deviation; mU of cholinesterase...

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Báo cáo khoa học: Transient potential receptor channel 4 controls thrombospondin-1 secretion and angiogenesis in renal cell carcinoma ppt

Ngày tải lên : 07/03/2014, 05:20

... CM and cell lysates (CM and L, respectively) were collected and TSP1 was detected by western blotting Note the low TSP1 secretion and higher intracellular levels in RCC cells (F) HNK and P769 cells ... loss in renal cancer A B Fig Role of TSP1 in angiogenesis, and localization in renal cells and tissue (A) Sections of RCC tumors and adjacent normal tissue (HNK) were stained for TSP1 and counterstained ... Fig Calcium uptake and mediators in HNK and RCC cells (A) Ca2+ uptake in response to VEGF by HNK and RCC cells HNK and RCC cells were preloaded with ﬂuo-4 acetoxymethyl ester and treated with 10...

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Kidney Cancer (Adult) - Renal Cell Carcinoma doc

Ngày tải lên : 15/03/2014, 00:20

... Clear cell renal cell carcinoma This is the most common form of renal cell carcinoma About out of 10 people with renal cell carcinoma have this kind of cancer When seen under a microscope, the cells ... cell carcinoma Renal cell carcinoma (RCC), also known as renal cell cancer or renal cell adenocarcinoma, is by far the most common type of kidney cancer About out of 10 kidney cancers are renal cell ... scans and magnetic resonance imaging (MRI) scans can find small renal cell carcinomas But these tests are expensive and cannot always tell benign tumors from small renal cell carcinomas For these...

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báo cáo hóa học:" Phase II trial of Modified Vaccinia Ankara (MVA) virus expressing 5T4 and high dose Interleukin-2 (IL-2) in patients with metastatic renal cell carcinoma" pot

Ngày tải lên : 18/06/2014, 15:20

... Characterization of T cell responses Characterization of T cell responses (A) CD8+CD107a+ effector cells, (B) CD8+perforin+ effector cells, (C) PD-1+ T cells, (D) CD4+CD25+FoxP3+ Tregs before and after treatment ... Figlin RA: Nephrectomy and interleukin-2 for metastatic renal- cell carcinoma N Engl J Med 2001, 345:1711-1712 Diner EK, Linehan M, Walther M: Response of papillary renal cell carcinoma in a solitary ... Heterogeneous Expression of the Tumor-associated Antigens RAGE-1, PRAME, and Glycoprotein 75 in Human Renal Cell Carcinoma: Candidates for T -Cell- based Immunotherapies? Cancer Res 1998, 58:4090-4095 Griffiths...

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báo cáo hóa học:" Epigenetic control of the ubiquitin carboxyl terminal hydrolase 1 in renal cell carcinoma" doc

Ngày tải lên : 18/06/2014, 15:20

... during the differentiation of renal tubules representing the origin of clear cell renal cell carcinoma (RCC) and in the regulation of the cell cycle of parietal epithelial cells of the Bowman's capsule ... discovered by cDNA microarrays and chemical genomic screening of head and neck squamous cell carcinoma [49] as well as pancreatic carcinoma lesions and pancreatic carcinoma cells either left untreated ... epithelium and RCC cell lines A) Representative COBRA analysis of three RCC tumor lesions and one RCC cell line Genomic DNA extracted from tumor lesions (2874TU, 2876TU and 2878) and the cell line...

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Báo cáo hóa học: " A pilot clinical trial testing mutant von HippelLindau peptide as a novel immune therapy in metastatic Renal Cell Carcinoma" doc

Ngày tải lên : 18/06/2014, 16:20

... interferon alfa in metastatic renal- cell carcinoma N Engl J Med 2007, 356:115-124 Hiles JJ, Kolesar JM: Role of sunitinib and sorafenib in the treatment of metastatic renal cell carcinoma Am J Health ... metastatic renal- cell carcinoma: a randomised trial Lancet 2001, 358:966-970 Marshall FF: Nephrectomy followed by Interferon alpha-2b compared with Interferon alpha-2b alone for metastatic renal- cell ... tumor-infiltrating lymphocytes for adoptive therapy of renal cell carcinoma (RCC) and metastatic melanoma: sequential proliferation of cytotoxic natural killer and noncytotoxic T cells in RCC J Immunother...

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Báo cáo hóa học: " Trichloroethylene exposure and somatic mutations of the VHL gene in patients with Renal Cell Carcinoma" potx

Ngày tải lên : 20/06/2014, 00:20

... diuretic use and coffee consumption as risk factors for renal cell carcinoma J Natl Cancer Inst 1986, 77:351-356 Bruning T, Weirich G, Hornauer MA, Hofler H, Brauch H: Renal cell carcinomas in ... non-null and NAT1 Slow/Rapid genotypes with VHL transversions in sporadic Renal Cell Carcinoma Pharmacogenetics 2001, 11:521-535 La Vecchia C, Negri E, D'Avanzo B, Franceschi S: Smoking and renal cell ... interests Authors' contributions BC and CB studied published data and conceived the study SG, DC, SF and SR performed the pathology and DNA analysis JF performed the exposure assessment AB was...

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RENAL CELL CARCINOMA pot

Ngày tải lên : 27/06/2014, 17:20

... renal cell carcinoma and oncocytoma shows no significant differences MR study of enhancement patterns of the clear cell, papillary, and chromophobe forms of renal cell carcinoma has been performed, ... mucinous tubular and spindle cell carcinoma (6-8) and tubulocystic carcinoma (5) While mucinous tubular and spindle cell carcinoma is now recognized as a distinct subtype of renal cell carcinoma (RCC) ... 32: 1369-1375 [130] Israel GM and Bosniak MA Renal Imaging for diagnosis and staging of renal cell carcinoma In Taneja SS ed Contemporary management of renal cell carcinoma Philadelphia: W B Saunders...

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Guidelines on - Renal Cell Carcinoma potx

Ngày tải lên : 06/08/2014, 17:21

... CXR CXR and US and US CT CXR and US CT CT years years years year CXR and US CXR and US CXR and US CT CXR and US CT CXR and US CT CT CXR and US CT CT After years Discharge Yearly CXR and US CXR/CT ... 5.6 Renal medullary carcinoma 5.7 Translocation carcinoma 5.8 Mucinous tubular and spindle cell carcinoma 5.9 Carcinoma associated with end-stage renal disease 5.10 Metanephric tumours 5.11 Renal ... Spindle and cuboidal renal cell carcinoma, a tumour having frequent association with nephrolithiasis: report of 11 cases including a case with hybrid conventional renal cell carcinoma/ spindle and...

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Báo cáo khoa học: "Haemostatics in surgery and our experience in the enucleoresection of renal cell carcinoma" ppt

Ngày tải lên : 09/08/2014, 03:21

... Association of Urology Guideline Group for renal cell carcinoma Renal cell carcinoma guideline Eur Urol 2007, 51:1502-10 12 Kulkarni R: Alternative and topical approaches to treating the massively ... wounds, and complications The best evidence for efficacy and safety exists for haemostasis, especially for nephrectomy and trauma Newer data highlight urinary tract reconstruction, fistula and percutaneous ... products and revision for bleeding were not required Median length of the postoperative hospital discharge was 2.5 days for FloSeal group and 3.5 for the Group (p < 0.05) Patients' discharge and removal...

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Báo cáo khoa học: "Abscess formation mimicking disease progression, in a patient with metastatic renal cell carcinoma during sunitinib treatment" docx

Ngày tải lên : 09/08/2014, 03:21

... Sunitinib for Metastatic Renal Cell Carcinoma Journal of Urology 2006, 672:19-20 (s) Dembry LM: Renal and perirenal abscesses Curr Treat Options Infect Dis 2002, 4:21-30 Geeting GK, Shaikh N: Renal ... and PDGFRbeta; VEGFR1, VEGFR2 and VEGFR3; KIT, FLT3, CSF-1R and RET) that was approved by the FDA in 2006 for treatment of metastatic renal cell carcinoma In a randomized phase III trial, sunitinib ... on T cells and antigen-presenting cells, such as dendritic cells, which play major roles in immune tumor surveillance Targeted tyrosine kinase inhibitor therapy may thus control cancer cell growth...

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Báo cáo khoa học: "Solitary colonic metastasis from renal cell carcinoma presenting as a surgical emergency nine years post-nephrectomy" pot

Ngày tải lên : 09/08/2014, 03:21

... References Rini BI, Campbell SC, Escudier B: Renal cell carcinoma Lancet 2009, 373(9669):1119-32 McNichols DW, Segura JW: Renal cell carcinoma- long term survival and late recurrence J Urol 1981, 126:17-23 ... pancreatic surgery for metastatic renal cell carcinoma Br J Surg 2009, 96(6):579-92 doi: 10.1186/1477-7819-8-54 Cite this article as: Jadav et al., Solitary colonic metastasis from renal cell carcinoma ... Bennington JL: Renal cell carcinoma recurrence 31 years after nephrectomy Arch Surg 1965, 90:192-5 Nakano E, Fujioka H, Matsuda M, Osafune M, Takaha M, Sonoda T: Late recurrence of renal cell carcinoma...

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Báo cáo sinh học: " Prediction of breeding values with additive animal models for crosses from 2 populations" ppt

Ngày tải lên : 09/08/2014, 18:22

... extension for traits: X and Y To obtain BLUP for X and Y the additive covariance matrices for traits X and Y, and between traits X and Y are needed The covariance matrix for traits X and Y can ... groups for breed I and for L The model of evaluation includes fixed effects of age (as a covariate), sex and genetic groups (Al, A2 and B), and random BV for animals through In order for [X:ZQ] ... and a are the additive covariances for traits X and Y L ) XY ( A I > x < Y A in populations L and I, respectively, and a is the additive segregation LI ) XY ( A covariance for populations L and...

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Báo cáo sinh học: "Inequality of maximum a posteriori estimators with equivalent sire and animal models for threshold traits" pps

Ngày tải lên : 09/08/2014, 18:22

... !i)/!! and or the 0’ error standard deviation (sire model) environmental standard deviation (animal model) For the heritability value of 0.20 the estimators from the sire model and the animal ... use of equivalent sire and animal models for the underlying variable and the use of the same estimation method lead to different estimators may be counterintuitive Under the animal model the maximum ... variable and to estimate the breeding values of the sires For that purpose let v’ l [!1!2 !3 !4], where v and v represent the additive genetic values on the underlying scale of the progenies and 2, and...

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