evolution of the cell s mechanical design

... known about the effects of environmental stiffness on vascular ECs, as well as on immune cells The substrate stiffness of ECs is relevant, because changes in the stiffness of the basement membrane ... leading to a cellular response 1146 ECs respond to shear stress A single sheet of ECs lines the walls of the arteries and is responsible for transmitting shear stress due to blood flow to the underlying ... the development of disease It is evident that the process involves a transmission of physical forces as the leukocytes pass through the endothelium The propagation of these forces through ECs...

Ngày tải lên: 22/03/2014, 21:20

... ft °F) There are several issues here requiring us to exercise caution First, the set of units presented is not consistent Next, the thickness of copper in via holes is given in terms of its weight ... these nondimensional numbers The set of interest to us is as follows: Nusselt Number The Nusselt number shows the relationship between a fluid 's capacity to convect heat versus its capacity to ... these equations The significance of these equations may be numerated as follows They produce exact solutions of any thermal/flow problems These equations could be reduced to the simpler forms...

Ngày tải lên: 03/06/2014, 01:25

... iodide stained cells DNA profiles are show from top to bottom as follows: asynchronous cells, S- phase cells (T = h; synchrony >97%), G2/M phase cells (T = h; synchrony >93%), and G1/GO phase cells ... proliferative signal in HEK293T cells Validation of predicted binding sites by luciferase assays In order to dissect the mechanisms of the miR-17-5p proliferative response, it was necessary to determine the ... follows the same profile as the pri-mRNA, with its highest expression in G2/M (Figure 1c) While it is clear that the miR17-92 locus is not essential for cell cycle progression (as many cell lines...

Ngày tải lên: 14/08/2014, 20:22

... discussion The Law has been translated into English by several translators An assessment of the English version of this law is thus desirable 2 Significance of the study The results of this study ... role of addresser: representative of the Socialist Republic of Vietnam specifying the rights and obligations of investors/addressees, as well as obligations and commitments of the State The role ... translation text is of the Transport Publishing House, a copy of which is available in Appendix B The same system of symbols is used to refer to sentences in the translation 2.2.1 Analysis of Source...

Ngày tải lên: 07/11/2012, 14:36

... billion years ago – 2.5 billion years ago: ♦ Some of the one-celled organisms in the oceans developed the ability to conduct “photosynthesis”: Process “Equation” Photosynthesis 6H2O + 6CO2 + sunlight ... (CH4) into the atmosphere ♦ Most of the H2O vapor condensed to form the oceans ♦ As a result of three key processes (outlined on the next slide), the air ended up consisting primarily of N2, CO2 ... Multi-celled organisms appeared, and some of these evolved into soft-bodied worm-like animals with a variety of organs, and still later into the first hard-shelled creatures capable of leaving fossils...

Ngày tải lên: 04/04/2013, 10:51

... kết thúc Ví dụ: "fax" kết thúc chữ "x" âm /s/ "like" kết thúc chữ "e" âm /k/Ngoại lệ: s từ kết thúc -ed dùng làm tính từ phát âm /Id/: * aged * blessed * crooked * dogged * learned * naked *...

Ngày tải lên: 18/09/2013, 06:10

... classical sinusoidal synchronous motor the average value of the torque is reduced With a faster time response, steady state torque is almost constant but the implementation of such system present ... 33 PROPOSAL OF AN EXTENSION OF THE PARK 'S TRANSFORMATION Classical Park 's transformation is in fact the succession of two transfomations The torque is then given by: T, = p.(@~,.io+@'did+@'q.iq) ... CONCLUSION The proposed extension of the Park 's transfonnation permits us to have a best knowledge of the non sinusoidal permanent magnet synchronous motor We are so able as well to analyse the classical...

Ngày tải lên: 03/01/2014, 19:50

... hour of birth Establishing good breastfeeding practices in the first days is critical to the health of the infant and to breastfeeding success Initiating breastfeeding is easiest and most successful ... children under They also discussed the benefits of exclusive breastfeeding in the first months of life and the risks of giving water instead of breast milk.119 Program-specific results are not available, ... ••First, Save the Children is increasing awareness of the global malnutrition crisis and its disastrous effects on mothers, children, families and communities As part of our campaign, this report...

Ngày tải lên: 12/02/2014, 11:20

... progress as a result of these decisions The state of Texas has sued CMS to prevent the loss of federal funds and a group of Planned Parenthood clinics has sued the state to prevent implementation of ... rise several-fold Paradoxically, as the number of WHP patients who can continue to be served climbs, the state s budget losses grow larger These are estimates based on some basic assumptions; the ... affiliate has a billing address in Dallas County, but some of its sites are in other adjacent counties and some of the patients served may be residents of other counties The list does not indicate...

Ngày tải lên: 13/02/2014, 06:20

... this report, the psychosocial effects are also enormous Girls are likely to find themselves in a position of powerlessness within the household of their husband s family, with no clear access ... account of adolescents, therefore, doubles the worldwide problem of children out of school Of these out -of- school adolescents, 54 per cent are girls The region most affected in this respect is sub-Saharan ... Needs Assessment (PDNA) process Childfriendly focus group discussions were held throughout nine of the country s departments Adolescents and youth who took part raised issues of gender, disability,...

Ngày tải lên: 15/02/2014, 00:20

... notional estimates Estimates subsidy rates will be determined at the time of execution, and will reflect the terms of the contracts and other characteristics The subsidy cost for TARP support of FHA ... value cost for each dollar of credit assistance It is comprised of four components—defaults, net of recoveries; interest; fees; and all other Loan characteristics describe the terms of the loan ... facilities Table DIRECT LOANS: ASSUMPTIONS UNDERLYING THE 2012 SUBSIDY ESTIMATES (In percentages, unless noted otherwise) Composition of Subsidy Agency, Bureau, Program and Risk Category Subsidy...

Ngày tải lên: 16/02/2014, 03:20

... mechanism of the Internet affect its robustness? How is the Internet s robustness changing while it is growing? Will performance and robustness of the Internet improve in the future? To answer these ... failures can be measured from a snapshot of the Internet We call this kind of analysis Static Analysis However, the Internet is a growing network and its topology changes continuously Does the growth ... other hand, S mainly considers the networks’ connectivity, showing how many nodes are connected to the largest cluster Since the S metric only considers the relative size of the largest connected...

Ngày tải lên: 18/02/2014, 01:20

... first customers, it s what you to help your first customers reach the rest Tight messages are required Look at how Apple focuses the message Mac was The Computer for the Rest of Us.” iPod was ... innate desire to share their passion for products and help create “lift” the irresistible force of millions of customers selling your product for you Just as Apple has harnessed this power more ... it frees their brain from having to “use” a computer Designers, authors, artists and your customers are all fans of good design and respond to those extra, thoughtful touches START WITH THE PACKAGING...

Ngày tải lên: 18/02/2014, 02:20

... Accordingly, agencies should be required to take steps to assess the cost of their sensitive unclassified information systems and ensure that safeguards not undermine the security of classified information ... the processing of the FOIA requests varied enormously The range of response times for the Card Memorandum request was 9-702 business days, and two requests are still pending over 750 business ... manner There are best practices in agencies that should be shared, as well as lessons to be learned about the costs and benefits of secrecy and disclosure Unnecessary secrecy has been on the rise since...

Ngày tải lên: 18/02/2014, 05:20

... This formerly was the most useless part of the house I there pass away both most of the days of my life and most of the hours of those days In the night I am never there There is by the side of ... or possession, or use, or enjoyment of the thing desired, as if one should say that the possession of money is the miser 's end, or the enjoyment of something pleasant the end of the sensualist ... weakness The conquest had no direct relation to the original purpose of the Crusades, which was the recovery of Jerusalem from the hands of the infidels.] The Best of the World 's Classics, Restricted...

Ngày tải lên: 18/02/2014, 06:20

... since the sequence of Ab was first determined, high-resolution structural analysis of Ab monomer and its assemblies has been hampered because of the lack of an affordable source of Ab peptides ... at least as pure as the synthetic peptides purified by reverse-phase HPLC, a finding corroborated by LC-MS analysis (Figs and S2 ) The fibril-forming properties of Ab peptides were assessed using ... as with the studies by Lee et al [21] and Subramanian and Shree [42], there was no rigorous assessment of the purity of the product or the correctness of the sequence In contrast, the purification...

Ngày tải lên: 18/02/2014, 13:20

... HIV and AIDS to maternal deaths is difficult to assess since, despite the expansion of programmes to prevent mother-tochild transmission of HIV, the HIV status of many pregnant women is still unknown ... survival, these are the results of sustained investment in all three areas The key to Sri Lanka s outstanding improvements in maternal health was the expansion of a synergistic package of health and social ... levels of all three of these identified risk factors It comes as little surprise that most of these nations are among the least developed and lowest-income countries Even within these countries,...

Ngày tải lên: 18/02/2014, 15:20

... conditions As the prevalence of physical and social settings of extreme deprivation increases, so does the risk of reversing the overall success of disease prevention and control efforts The urban ... areas They may resort to these substances as a means of coping with stress or as an outlet for idleness and frustration in the absence of employment or opportunities for recreation such as sports ... settings – even more so when disaster pushes large numbers of people into these areas The results of such a surge in users can include the contamination of drinking water Sanitary toilet systems consisting...

Ngày tải lên: 18/02/2014, 15:20

... Africa, Pakistan, Nepal and Southeast Asia These investments are smart business When this understanding grows and creates the necessary political will, the lives of women and children in the developing ... partners And Professor Peter Singer refutes the common myth that saving children is somehow at odds with protecting the environment Some of the solutions that could save the most lives may surprise ... But the reality is that foreign aid spending is less than six-tenths of percent of the U .S budget We should spend more, not less, to save children s lives Hard economic decisions are necessary,...

Ngày tải lên: 18/02/2014, 15:20