evidence from experimental models and humans and new prospectives for treatment

... industry-standard equipment for loading and discharging containers to and from vessels Quay cranes are very expensive (around 10 million Singapore dollars for individual machine) and quay cranes ... existing models for the problems of quayside CHAPTER INTRODUCTION operations and provide the revised model and new algorithms for solution (see the work in Chapter 4); • Extend the existing models ... noted that apart from the aforementioned analytical models for BAP, simulation techniques have also been applied to handle the problem, such as the works by Legato and Mazza (2001) and Henesey et...

Ngày tải lên: 10/09/2015, 15:48

... invertebrates and vertebrates Drosophila has only one gene for Serrate and one for Delta, whereas in mammals five genes encode the Notch ligands: Serrate homologues called Jagged1 and 2, and Delta ... previously described for hMSCs For a better understanding of the origin of dedifferentiating chondrocytes, these authors [76] isolated and cultured human articular chondrocytes and hMSCs and compared ... the Notch receptor is needed for cell differentiation and proliferation before birth in order to form the cartilage elements During the late stages of development and after birth the expression...

Ngày tải lên: 12/08/2014, 15:22

... Social and Economic Burden, edited by K B Weiss, A S Buist, and S D Sullivan 139 New and Exploratory Therapeutic Agents for Asthma, edited by M Yeadon and Z Diamant 140 Multimodality Treatment ... Sleep and Breathing in Rodents References Neurochemical Evidence for the Cholinergic Modulation of Sleep and Breathing Ralph Lydic and Helen A Baghdoyan I II III IV V VI VII VIII Experimental Models ... driving and work performance (4,5); hypertension (6); increased risk for stroke, angina, and myocardial infarction (7); and suppressed ventilatory and arousal responses to altered blood gases and...

Ngày tải lên: 14/02/2014, 17:20

... RPs in human pathologies and animal models Ribosome deficiencies due to mutations in the genes coding for RPs or for rRNA have been known for many years in Drosophila and Xenopus [59–61] In both ... smaller organs and smaller stature In addition, fibroblasts from RPL29-null embryos show decreased rates of proliferation and protein synthesis Therefore, RPL29 is dispensable for embryonic development, ... growth factors, hormones, and nutrients, can induce a change in the percentage of TOP mRNA associated with polysomes from 30–40% to 65–75%, and vice versa [33] Several lines of evidence converge in...

Ngày tải lên: 07/03/2014, 01:20

... of sequence information is currently not an option Therefore, given the scarce knowledge on relevant ligands and substrates and the experimental drawbacks of overexpression in cell models, insight ... subsequently moves into the nucleus and enhances secretory granule gene expression by binding and protecting STAT5 phosphotyrosines For the R4 (RPTPa and RPTPe) and R5 (RPTPc and RPTPf) receptor-type PTPs ... community and public health Acknowledgements We thank Frank Bohmer, Rob Hooft van Huijsduij¨ ¨ nen and Arne Ostman for critical reading of the manuscript, and Noriko Uetani and Michel Tremblay for...

Ngày tải lên: 30/03/2014, 04:20

... airline, banking, advertising, and gasoline and grocery retailers and cement (Weiss 1989, Schmalensee 1989, and Werden 1991, and Koller and Weiss 1989) and notwithstanding that there has been an ... which came from Canada The rest of the imports came from Brazil, Chile, Finland, New Zealand, Portugal, Spain and Sweden 10 The American Forest and Paper Association (AFPA) estimates that the costs ... basis, new supply increased from 557.6 pounds in 1982 to 687.6 in 2002 (a 23.3% rise) after peaking in 1999 at 754.2 pounds per capita And new supplies of paper and paperboard output accounted for...

Ngày tải lên: 01/04/2014, 00:20

... workforce performance and retention are also discussed Methods Our study employs data from the Assessment of Human Resources for Health, a multi-country survey implemented with technical and ... from the regression analyses for nursing and midwifery personnel are reported in Table and paint a complex picture Across the six countries, after controlling for wages, years of experience and ... aspect of the health workforce requires better measures of men and women in the health workforce, to help identify and prioritize evidence- based gender-sensitive HRH planning and management interventions...

Ngày tải lên: 18/06/2014, 17:20

... nonhuman primate and rodent models of prenatal stress and early adverse caregiving13,14,16 have helped us understand the consequences of similar experiences in humans. 17,18 Maternal and fetal stress ... factor for later psychopathology: evidence from rodent and primate models Dev Psychopathol 2001;13:419–49 14 Sanchez MM The impact of early adverse care on HPA axis development: nonhuman primate models ... primate and rodent models of early adverse caregiving13,14,16 have helped us understand the consequences of similar experiences in humans. 17,18 Disturbed regulation of stress systems (eg, HPA axis and...

Ngày tải lên: 08/08/2014, 21:20

... particularly for small samples However, analysis of the currently available data does yield some evidence and may help to raise awareness and efforts to improve the data and methods for addressing ... detailed comparison of surveillance data from China, Kuwait, and the U.S We conclude with a plea for more research and attention on this critical issue for health and globalization Background: The challenge ... course, methods for aggregation and comparing patterns of resistance across countries and over time should be improved, and applied more fruitfully with better data from increased local and global...

Ngày tải lên: 11/08/2014, 18:20

Ngày tải lên: 18/05/2015, 03:42

... risk and social preferences from an empirical and experimental perspective We use biological data, in addition to observable choice data and field data, to investigate the determinants of risk and ... – for assistance in DNA extraction and genotyping, Roy Chen, Song Changcheng, and Zhong Songfa for insightful comments and suggestions in the data analysis This study was supported by grants from ... ………………………………………………………………… 53 2.3.1 Empirical Strategy ………………………………………………… 53 2.3.2 Evidence from Incentivized Experimental Games ……………… 54 2.3.3 Evidence from China Family Panel Studies Data ……………… 69 2.3.4 Discussion...

Ngày tải lên: 09/09/2015, 08:13

... firm-level data and are able to provide only indirect evidence For example, Anderson and Garcia-Feijoo (2006) and Xing (2006) document an association between the capital investment rate, a proxy for the ... included For example, I include Genentech, which was partially owned by Roche For each firm, I collect financial data from Compustat and daily stock return data from the Center for Research and Security ... Green and Naik, 2004) Unlike in other industries, growth options of pharmaceutical and biotech firms are clearly demarked as they come in the form of new patents and drugs created after costly and...

Ngày tải lên: 30/09/2015, 16:34

... people (1291) and related ventilation and, to a lesser amount, the load from internal equipment and lights For example, the hospital average lighting and plug loads were 12.68 W/m2 and 23.18 W/m2, ... along with the “Machinery and Engines” and “Air conditioning, Refrigeration, and Warm Air Heating Equipment” for the appropriate industry and sector categories Results and discussion The following ... Initiative Models [19], and Economic Input-Output Life Cycle Assessment Model (EIO-LCA) [20] Information and data regarding building specifications and operational energy consumption were obtained from...

Ngày tải lên: 05/09/2013, 15:28

... contributions LM and AV conceived the study, and participated in its design and coordination and helped to draft the manuscript All authors read and approved the final manuscript 15 16 17 Authors information ... [anogenital cancer and warty lesions], have accompanied humans throughout evolution Therefore, differently from the quasi-species of many RNA viruses, HPV types have evolved very slowly, and have diverged ... over time from the immune response and therefore, indicates that the HPV L1 capsid-specific antibody is not a suitable diagnostic test for HPV infection Other HPV antigens [E1, E2, E6, and L2]...

Ngày tải lên: 18/06/2014, 16:20

... stakeholders A new approach for modern supply chain could be proposed to apply for cabbage and water melon to meet market requirement and consumer demand for higher food quality and safety: - ... total sample for cabbage, and total fruits per total sample for water melon III Result and discussion 3.1.Supply chain mapping for cabbage and water melon After harvesting, cabbage and water melon ... on spoilage reduction Postharvest treatments (lime or alum for cabbage and chlorine for water melon) reduced spoilage significantly A post harvest handbook and TOT/FFS training courses need to...

Ngày tải lên: 21/06/2014, 04:20

... non-spore forming, motile, catalase-positive, and cytochrome oxidase-positive Gelatin and starch were not utilized In addition to these morphological and physiological properties, the carbohydrate and ... P-19486 alliinase for (±)-alliin was 2.3 mM, and was apparently lower than that for (+)-alliin (5.7 mM), suggesting that the Km value for (-)-alliin might be around mM or less We therefore examined ... glycoproteins consisting of two identical subunits (Schwimmer and Mazelis 1963; Mazelis and Crews 1968; Tobkin and Mazelis 1979; Nock and Mazelis a 1986; Landshuter et al 1994; Lohmüller et al 1994; Rabinkov...

Ngày tải lên: 21/06/2014, 05:20

... tools for PKM (Personal Knowledge management) are discussed Educational uses of wikis and blogs are outlined Blogs and wikis represent new repositories of information and knowledge for personal and ... networking processes and a community model to foster knowledge sharing and collaboration Blogs and wikis represent new repositories of information and knowledge for personal and organisational ... as a standalone version and can be seen as personal information managers An example of a Methodologies, Tools and New Developments for E-Learning personal wiki is Pimki (http://pimki.rubyforge.org),...

Ngày tải lên: 27/06/2014, 05:20

... long-span and high-rise building forms, materials transitioned from their pre-modern role of being subordinate to architectural needs into a means to expand functional performance and open up new formal ... decision-making responsibility from the architect, and as such, it is less about informed choice and optimization and more about specification and standardization The result is information, not knowledge ... and remove liability for performance failures For many uses, codes and standards often explicitly or implicitly identify acceptable materials, leaving the architect only to select between brands...

Ngày tải lên: 27/06/2014, 17:20

Ngày tải lên: 05/08/2014, 09:46

... mangrove forest Therefore, the project of planting mangroves and trees against sand [2] is the best way to prevent climate change in many respects, and two of the many benefits that energy and new ... The technological transformation of biomass into fuels and new materials for Vietnam's scientists can help this program to lower cost and more flexible than the import of foreign technology We ... mangroves and coastal areas against sand is needed, but also to prepare the technology together so that people can live and income on these areas so that they stick with mangroves and sand The...

Ngày tải lên: 27/04/2015, 09:10