evaluation of motility defective vaccine candidates

... potential vaccine candidates These two viruses were first evaluated for their level of temperature sensitivity of replication in vitro (Table 2) The level of temperature sensitivity of rHPIV1-CR84G/ ... (A) and LRT (B) of AGMs rHPIV1 wt and non-ts rHPIV1 mutants were assigned a shut-off temperature of 40°C for the purposes of this schematic The limit of detection for the mean sum of daily virus ... clinical grade virus preparations Evaluation of the two vaccine candidates revealed that they are reasonable candidates for further study in clinical trials Both candidates replicated well in Vero...

Ngày tải lên: 18/06/2014, 18:20

... potential vaccine candidates These two viruses were first evaluated for their level of temperature sensitivity of replication in vitro (Table 2) The level of temperature sensitivity of rHPIV1-CR84G/ ... (A) and LRT (B) of AGMs rHPIV1 wt and non-ts rHPIV1 mutants were assigned a shut-off temperature of 40°C for the purposes of this schematic The limit of detection for the mean sum of daily virus ... clinical grade virus preparations Evaluation of the two vaccine candidates revealed that they are reasonable candidates for further study in clinical trials Both candidates replicated well in Vero...

Ngày tải lên: 20/06/2014, 01:20

... Y and Dederding, J P Evaluation of small intestinal motility Schweiz Med Wochenschr Suppl 1993, 54, 26-31 30 Weisbrodt, N W Motility of the small intestine in Physiology of the gastrointestinal ... for small intestinal motility evaluation in dogs mazine administered group, respectively The number of peristaltic waves in the xylazine HCl treated group was lower than those of the control group(p

Ngày tải lên: 07/08/2014, 14:23

... objective of determining whether the recombinant E coli vaccine would elicit a different cytokine profile relative to control E coli However, because of the mixed Th1/Th2 cytokine profile of the ... indicate efficient plasmid delivery expressing Microfluorimetry of supernatant of HeLa cells after infection Microfluorimetry of supernatant of HeLa cells expressing murine IL12 indicate efficient ... limiting vaccine efficacy [75] The cytokine profile of the primary immune response to our recombinant E.coli vaccine vector revealed a mixed Th1/Th2 profile suggesting a high population of CD4+...

Ngày tải lên: 11/08/2014, 08:21

... therefore allowing a direct comparison of the expression level of a given protein from a standard amount of genetic material Surprisingly, the expression of gag and nef, in the linear range, appeared ... as with the addition of adenovirus that does not contain the coding region for any transgene of interest The mere presence of additional "empty" adenovirus particles devoid of transgene appears ... Development and use of a novel in vitro assay for testing of diphtheria toxoid in combination vaccines J Immunol Methods 2009, 350:142-9 Pecora A, et al.: Development and validation of an ELISA for...

Ngày tải lên: 12/08/2014, 04:21

... efficacy of DNA vaccines against anthrax include coadministration with a DNA vaccine expressing LF, and a DNA prime / protein boost regimen [20] or the use of cationic lipids [22] The aim of this ... shown to improve the performance of DNA vaccines [2326], was fused to either the N- or the C-terminus of PA63 We show that following gene gun administration of these vaccines, fusion with VP22 does ... a number of antigens not only in the context of gene therapy, but also when fused to antigens within a DNA vaccine This could be particularly useful because although DNA vaccines can offer protection...

Ngày tải lên: 14/08/2014, 19:22

... observation of cyclic edema demonstrated the success of the treatment and the need for its control, but we had no idea of the high prevalence of edema in the more advanced grades of cellulite The lack of ... were excluded An evaluation for idiopathic cyclic edema is routinely made in the diagnosis of cellulite, in obesity and in other evident causes of clinical edema The diagnosis of idiopathic cyclic ... and with the combination of drugs control of edema was attained Discussion This study illustrates the association of idiopathic cyclic edema with more advanced cases of cellulite There are no...

Ngày tải lên: 25/10/2012, 10:51

... the prevalence of low back pain of 162% with an annual increase of 11.6% The widely held belief that most of the episodes of low back pain will be short-lived, with 80% to 90% of these attacks ... lumbar radiofrequency neurotomy.29-31 The exact mechanism of the therapeutic effect of lumbar facet joint nerve blocks is not known, whereas radiofrequency neurotomy causes denaturing of the nerves ... Classification of Chronic Pain; Descriptions of Chronic Pain Syndromes and Definition of Pain Terms, 2nd ed; Task Force on Taxonomy of the International Association for the Study of Pain Seattle:...

Ngày tải lên: 26/10/2012, 09:07

... in 88.4% of cases and in 93.8% of controls The informed consent document was signed by 98.4% of case mothers Personal identifiers (i.e name and address) were deleted from the record of cases ... keep them The personal data of controls are not recorded in the HCCSCA The fourth step was the evaluation of maternal infusion in five different aspects 1) The source of information All infusion ... of infusion according to the month of gestation in the case and controls groups is shown in Table There were two peaks of infusion treatments The first peak was connected with the treatment of...

Ngày tải lên: 02/11/2012, 11:08

... activity of disease in sarcoidosis or HP In addition, finding of encapsulated exudates may suggest desquamation of early stage of Masson body which implies possible diagnosis in a limited number of ... Patients’ group showing the highest rate of lymphocytes Of the 2260 patients, 488 (21.6%) showed a lymphocyte rate of higher than 40% Clinical diagnoses of these patients included sarcoidosis (22.1%), ... infiltration of mast cells implies histological feature of organization of collagenous matrices or interstitial fibrosis 10 Basophilic leukocytes were never found in the normal control and most of the...

Ngày tải lên: 03/11/2012, 11:48

... in materials evaluation including definitions of materials evaluation, purposes for materials evaluation, types of materials evaluation, materials evaluators, models for materials evaluation, ... purposes of the course as well as the available facilities and constraints of a particular situation 1.2 Materials Evaluation 1.2.1 Definitions of Materials Evaluation There are many ways of defining ... research 1.2.3 Types of Materials Evaluation In materials evaluation literature different authors offer different ways of categorizing it Robinson (1991:59) classifies materials evaluation into three...

Ngày tải lên: 07/11/2012, 14:50

... evaluation, etc Teacher evaluation task evaluation, etc Learners evaluation evaluation of sequencing practice, ect evaluation of levels of participation etc Figure 3: Macro- and micro -evaluation in language ... purpose of the evaluation 1.2.2 Types of programme evaluation According to Stufflebeam (1971), there are four types of programme evaluation which are identified as: context evaluation, input evaluation, ... ESP (definition of ESP, classification of ESP and the development of ESP), evaluation (terminology definition, types of programme evaluation, purposes for evaluation, criteria for evaluation and...

Ngày tải lên: 07/11/2012, 14:54

... the discretization steps of Ds became different in the course of the test For the next steps of Dsn calculated as above, excess of the pore water pressure Evaluation of consolidation parameters ... used formulae and the Fig Comparison of different methods of cv estimation in the context of theoretical analysis of the CL consolidation process Evaluation of consolidation parameters in CL tests; ... the changes of Hi length of the drainage path This point Fig Comparison of cv characteristics estimated by various methods A — estimation of cv value by different formula; B — changes of cv v l...

Ngày tải lên: 22/03/2013, 15:01

... INSTITUTE OF EDUCATION AND RESEARCH UNIVERSITY OF PESHAWAR (2005) EVALUATION OF INSTRUCTIONAL METHODS USED IN TEACHING OF ENGLISH IN SECONDARY SCHOOLS OF HARIPUR DISTRICT Submitted ... sphere of this mortal life APPROVAL SHEET The thesis entitled Evaluation of instructional method used in teaching of English In secondary schools of Haripur District Accepted by the faculty of ... 1-3 I 1.1 Background of the Study 1.2 Statement of the Problem 1.3 Objectives of the Study 1.4 Significance of the Study 1.5 Hypothesis 1.6 Delimitation of the Study II REVIEW OF RELATED LITERATURE...

Ngày tải lên: 10/04/2013, 10:37

... works Evaluation is implemented in phases of investment process: Inception evaluation; Midterm evaluation; Completion evaluation; Impact evaluation or after project evaluation Monitoring and Evaluation ... implementation Evaluation - Internal evaluation - External evaluation - Implementation - Results - Impacts - Inception evaluation - Midterm evaluation - Completion evaluation - Impact evaluation ... Ministry of Culture, Sports and Tourism IS Information System IT Information Technology M&E Monitoring & Evaluation MPI Ministry of Planning and Investment MOF Ministry of Finance MBA Master of Business...

Ngày tải lên: 18/04/2013, 16:01

... 1.  FT-IR spectra of PA (a) and pullulan (b) 500 Stability and in vivo evaluation of pullulan acetate   555 (2008) also reported that the smaller size of NPs may be in favor of longer circulation ... integration value of acetyl protons at 1.8–2.2 ppm and B is that of OH protons and H-1 to H-6 protons of pullulan moiety observed at more than 3.5 ppm Preparation and characterization of PANs and PA/EPI ... informahealthcare.com by University of Technology Sydney on 03/01/11 For personal use only Stability and in vivo evaluation of pullulan acetate   553 aqueous media The hydrophobic core of these selfassembled...

Ngày tải lên: 23/04/2013, 21:38

... as the port of entry, the names of the importer and exporter, a detailed description of the goods, the quantity of the goods, the value of the goods, the currency, and the country of origin Specific ... why I chose Evaluation of the real situation of import activities of Vietnam energy development support joint stock company from 2009 to 2011 Problems and solutions” as the subject of this report ... the activities of the company in recent years that I researched during my internship period, I would like to make a report on: Evaluation of the real situation of import activities of Vietnam energy...

Ngày tải lên: 24/07/2013, 09:11