ethical challenges in the management of twin twin transfusion syndrome

... cultures of the offspring are of interest for following reason In contrast to the situation in the testes of bulls born as cotwins to freemartins in which any XX cells are at a disavantage in having ... against cells with a normal karyotype (M et al., 1980) ORAES Because of the chimeric nature of the twins and the rarity of the insertion in the population, it was concluded that, in terms of ... resolved in the bulls because of the conflicting reports regarding the ability of XX germ cells to survive in the testis In some matings from these bulls, claims have been made that they can...

Ngày tải lên: 09/08/2014, 22:22

... in the development of the oxidative stress (68) If our findings are proven by further studies involving a larger number of patients, ultra-low microcurrent therapy might change the concept of management ... and the metabolic syndrome (30) In these conditions there is an elevation of both glucose and free fatty acid levels in the blood and an increase in oxidative stress (30,31) The high degree of ... pathogenesis of insulin resistance in humans using magnetic resonance spectroscopy Obesity (Silver Spring) 2006;14 (Suppl 1): 34S–40S 31 Boden G Role of fatty acids in the pathogenesis of insulin resistance...

Ngày tải lên: 26/10/2012, 09:39

... within seconds of coming into contact with them Almost all of the remaining phenol binds to the nerve tissue during the following few minutes; by 15 minutes from the start of the phenol administration, ... 0.1% of the administered dose remains in the CSF (Ichiyanagi et al., 1975) The magnitude of the clinical effect of the intrathecal block depends on the concentration of phenol and also on the ... second injection, the treatment effect is often enhanced by the additional in ltration of the proximal third of the muscle The superficial placement of the injection may result in the denervation of...

Ngày tải lên: 01/11/2013, 10:20

... DSTI/ICCP(2007)20/FINAL MAIN POINTS One of the major challenges for all stakeholders in thinking about the future of the Internet is its ability to scale to connect billions of people and devices The objective ... for the future of the Internet economy is the deployment of IPv6 DSTI/ICCP(2007)20/FINAL In terms of public policy, IPv6 plays an important role in innovation and scalability of the Internet In ... IPv6 In other words, once the cost of deploying IPv4 infrastructure – determined by the cost of obtaining the addresses themselves and the cost of designing and operating networks that use fewer...

Ngày tải lên: 06/03/2014, 21:20

... Katrina and evacuation to the RAC The trauma resulting from the disaster, the process of evacuation, the disruption of regular care, and the stress of residing in the shelter complex further increased ... descriptive summary of the 72 individuals examined The data analysis occurred in two phases The first phase consisted of matching the database entries with the original hard copy versions of the SWiFT ... to offsite housing facilities In some cases, they took their money, and upon discovery of the extent of the elders’ needs, returned them to the shelter One of the problems that occurred at the...

Ngày tải lên: 28/03/2014, 16:20

... Caffeine ngừng thở trẻ thiếu tháng (Caffeine for Apnea of Prematurity - CAP) ý đến tác dụng kéo dài điều trị caffeine cho trẻ sơ sinh Trong thử nghiệm lâm sàng chu sinh lớn nhất, 2,006 trẻ sinh ... Hiệu indomethacin ibuprofen tương tự ibuprofen liên quan với tỷ lệ tác dụng bất lợi thận thấp Hiện có đủ chứng lợi ích trước mắt cải thiện kết lâu dài điều trị PDA với indomethacin ibuprofen ... đóng ống động mạch thuốc Dịch từ “European Consensus Guidelines on the Management of Neonatal Respiratory Distress Syndrome in Preterm Infants – 2010 Update” Neonatology 2010;97:402–417 Người dịch:...

Ngày tải lên: 08/06/2014, 06:58

... fixed to the rings of the Ilizarov device Intraporative photograph showing the way the wires are Intraporative photograph showing the way the wires are applied and fixed to the rings of the Ilizarov ... in drafting of the manuscript and in the interpretation of data TGB performed part of the literature review and contributed in the manuscript editing SP, EP, AK and GT contributing in analyzing ... removal of the device and was re-operated because of unawareness of the mechanism of injury and underestimating the ligamentous instability of the ankle joint (Figure 6) In patients of group...

Ngày tải lên: 20/06/2014, 04:20

... urticaria, just as the histology of the two groups is strikingly similar.27,45 All of these findings provide a basis for further investigation of the pathogenesis and treatment of this disease.46–48 ... prominent in the lesions of chronic urticaria than in the late-phase response Cytokine Production after Stimulation with PMA–Ionomycin: Phenotypic Characterization of the Cytokine-Producing Subpopulation ... against the eosinophil low-affinity IgE receptor (CD23), which activate eosinophils and induce histamine release by eosinophie cationic protein (ECP), major basic protein (MBP), or other eosinophil...

Ngày tải lên: 08/08/2014, 21:20

... subjects received their first dose of aripiprazole at the start of the switching treatment period, the starting dose of which was determined by the investigator After weeks of adverse event (AE)-free ... shown in Figure Both patient and caregiver POM ratings for aripiprazole increased during the 12-week switching phase At the end of the switching phase (LOCF), 54.7% of 123 subjects and 48.0% of ... be fully representative of all patient types encountered in real-world settings Furthermore, the findings reported here should also be interpreted within the context of the open-label study design...

Ngày tải lên: 09/08/2014, 01:21

... Since there are commonalities in the pathophysiology of PAH and RP, particularly in the context of connective tissue disease, inhibition of the renin–angiotensin system may prove effective in ... than nifedipine in reducing both the frequency and the severity of attacks [14] PDE type V inhibitors such as sildenafil inhibit the degradation of cGMP, which mediates the signalling of several ... combine vasodilator and antiproliferative activity include angiotensin-converting enzyme inhibitors, angiotensin receptor blockers and PDE type V inhibitors [5] The use of angiotensin-converting...

Ngày tải lên: 09/08/2014, 06:23

... none of the individual components of the VNPI reached statistical significance, suggesting that the whole Index is of greater value than its parts Adding age to the index reduced rather than increased ... mm) The anatomical constraints obviously limit further excision of close margins in the cross sectional plane and there is no advantage to be gained in re-excision if DCIS approaches the margin ... initial margins between 1–5 mm underwent further surgery resulting in a total re-excision rate of 33% (n = 72) There were non invasive and 11 invasive recurrences in the treated breast during the follow...

Ngày tải lên: 09/08/2014, 07:21

... losses in other domains [22] The role of leisure in maintaining or restoring psychological wellbeing in the presence of arthritis pain warrants further study Psychosocial approaches to managing ... psychosocial functioning and coping of mothers with chronic pain (including mothers with arthritis) to mothers without pain, with regard to their ratings of parenting efficacy There was a significant ... comparison of conventional pain coping skills training and pain coping skills training with a maintenance training component: A daily diary analysis of short- and long-term treatment effects J Pain 2006,...

Ngày tải lên: 09/08/2014, 08:23

... modifier of hemoglobin that works by decreasing the binding affinity of hemoglobin to oxygen thus permitting greater oxygenation of hypoxic tumor cells and enhancing the effect of radiation In addition ... difference in survival These results have not been strong enough to bring any of these agents into routine clinical care At this time there are several clinical trials underway involving other potential ... beginning radiotherapy Many potential therapies being investigated also carry a risk of neurocognitive decline and the current focus of brain metastases research is to find ways to optimize the...

Ngày tải lên: 09/08/2014, 09:22

... seemingly paradoxical result can be explained in the following way The chance of finding a seed-match and of producing a local alignment of significant similarity rises with the length of the ... (Figure S3 in Additional file 1) Therefore, requiring a minimum distance in bitscore between the best and second best hit is Page of 15 very effective in removing most of the remaining reads that ... location of the human and chimp hits for each read is verified by using liftover [50] to map the coordinates of the human hit to the chimpanzee genome and the coordinate of the chimpanzee hit to the...

Ngày tải lên: 09/08/2014, 20:22

... Indications for therapy The 1996 NCI Working Group established guidelines for initiating treatment for CLL, which were affirmed in 2008 by the International Workshop on CLL[1,2] Indications include ... preclinical results of an ongoing phase I study of CAL-101, an orally available inhibitor of the phosphatidylinositol-3-kinase (PI-3-K) delta isoform, will be presented at the ASCO meeting Other novel ... del(17p13) are the largest therapeutic challenge in the relapsed setting, particularly given the increasing frequency of del(17p13) in relapsed patients Alemtuzumab is active in these patients,...

Ngày tải lên: 10/08/2014, 22:20

... eight cases into one case series because the surgical management of the eyelid injuries was the same, although the systemic managements of these patients as different according to the injury area ... possible Early skin grafting increases the risks of infection and complications However, delayed skin grafting also increases the risk of eyelid hypertrophic scarring, asymmetry and other deformities ... fold on the graft, allowing extra skin for future graft contracture while still preserving the ability to close the eye adequately We widen the grafting area by separating and loosening the musculus...

Ngày tải lên: 10/08/2014, 23:22

... unknown, since the nodules were not sent for pathological analysis The clinical significance of these nodules is also unknown, since they could interfere with the surrounding branches of the greater ... reviewing and editing the manuscript EDS contributed to the review and editing of the manuscript All authors read and approved the final manuscript Competing interests The authors declare that they ... led the study investigators to conclude that patients with NF-1 are at greater risk for headaches than the general population Another interesting finding of the study was that 38 (47%) of the...

Ngày tải lên: 11/08/2014, 00:23

... Drafted the overall design of the manuscript, the otolaryngology management part and collect all the figures and photos JMA: Drafted the neurosurgical part of the management SJWD: Drafted the clinical ... copy of the written consent is available for review by the Editor -in- Chief of this journal Acknowledgements The authors would like to thank Dr Madhavan with his help in the interpretation of the ... episodes of epistaxis and deterioration of vision On examination there was a mass in the right nasal cavity extending across the postnasal space on either side Fundoscopy revealed signs of left...

Ngày tải lên: 11/08/2014, 10:23

... thrombosis, there not appear to be any real alternatives in the management of fractures involving the anterior column of the acetabulum The ilio-inguinal route provides the benefits of a low complication ... exposed to the blood flow [8-10] In the case of our patient, the combination of an initial endothelial lesion, intermittent haemostasis during surgery, and further arterial trauma as a result of fracture ... segments This force will act against the tethering effect of the medially coursing internal iliac and inferior epigastric vessels [7] The net forces may favour intimal lesions and plaque rupture,...

Ngày tải lên: 11/08/2014, 10:23

... discontinuation of the infusion and removal of the intravenous catheter [1] The diagnosis of PGS is based on the characteristic clinical findings and a high index of suspicion when it occurs after the administration ... or if the cannula is kinked, leading to stasis Another possible mechanism could be that the highly alkaline solution induces vasoconstriction of the vein resulting in disruption of the endothelial-intercellular ... from injection site infection Intra-arterial injection of a highly alkaline solution would 20 G intravenous Cannula inserted into the interscalene groove for continuous infusion of bupivacaine...

Ngày tải lên: 11/08/2014, 11:22