epigenetic epidemiology of type 1 diabetes

... Thi Minh Nguyet • Received: 14 February 2 011 / Accepted: 19 April 2 011 / Published online: 13 May 2 011 Ó Japan Human Cell Society and Springer 2 011 Abstract Type diabetes occurs when pancreatic ... Human Cell (2 011 ) 24:86–95 DOI 10 .10 07/s13577- 011 -0 018 -z RESEARCH ARTICLE Improving the efficacy of type diabetes therapy by transplantation of immunoisolated insulin-producing ... Overall, 90.23 ± 1. 25%, 85 ± 1. 95%, 92 ± 2 .15 % and 50 ± 3.29% (n = 3) of mMSCs and 72 ± 1. 34%, 75 ± 2 .18 %, 83 ± 2.52%, and 73 ± 4.32% of hMSCs were positive for CD13, CD44, CD90, and CD166, respectively

Ngày tải lên: 14/12/2017, 17:57

... S 016 8-8227 (17 )303 51- 0 http://dx.doi.org /10 .10 16/j.diabres.2 017 .02.033 DIAB 6893 To appear in: Diabetes Research and Clinical Practice Received Date: Revised Date: Accepted Date: 29 March 2 016 12 ... Costs of Type Diabetes Mellitus in Pediatric patients in Spain: CHRYSTAL Observational Study, Diabetes Research and Clinical Practice (2 017 ), doi: http://dx.doi.org /10 .10 16/j.diabres.2 017 .02.033 ... social-economic costs of Type Diabetes Mellitus (T1DM) in patients aged 0? ?17 years in Spain from a social perspective Methods We conducted a cross-sectional observational study in 2 014 of 275 T1DM pediatric

Ngày tải lên: 04/12/2022, 16:37

... quality of life (HRQoL) of children with type diabetes mellitus (T1DM): self and parental perceptions Pediatr Diabetes 2 011 , 12 (1) :34-40 Pishdad GR: Low incidence of type diabetes in Iran Diabetes ... 19 (10 ) :15 011 508 11 16 Jafari P, Ghanizadeh A, Akhondzadeh S, Mohammadi MR: Health-related quality of life of Iranian children with attention deficit/hyperactivity disorder Qual Life Res 2 011 , 20 (1) : 313 6 ... quality of life of Iranian children with type diabetes: reliability and validity of the Persian version of the PedsQL Generic Core Scales and Diabetes Module Health and Quality of Life Outcomes 2 011 ,

Ngày tải lên: 20/06/2014, 15:20

... provide the youth’s diabetes type (youth %, n = 15 ; parents 15 %, n = 16 1);  the youth did not have T1DM, i.e reported type diabetes or an “other type? ??, e.g Maturity Onset Diabetes of the Young (youth ... people aged 10 ? ?12 years (63 items) (ii)young people aged 13 ? ?19 years (16 9 items) (iii)parents of young people aged 10 ? ?19 years (17 6 items) Additional file provides a description of the scales ... Psychology (2 016 ) 4:42 DOI 10 .11 86/s40359- 016 - 014 9-9 STUDY PROTOCOL Open Access Diabetes MILES Youth–Australia: methods and sample characteristics of a national survey of the psychological aspects of living

Ngày tải lên: 10/01/2020, 13:32

... 0.34 (0 .11 ? ?1. 05) 0 .10 0. 41 (0 .14 ? ?1. 22) 0 .18 0.87 (0. 41? ? ?1. 82) 0.85 0.20 (0 .10 –0.39) < 0.00 01 0.23 (0 .12 –0.45) < 0.00 01 0.60 (0.33? ?1. 07) 0 .11 0 .17 (0.20–0.30) < 0.00 01 0.28 (0 .17 –0.47) < 0.00 01 bb ... 77 /14 1 (55) 11 3 /14 1 (80) 10 0 /14 1 ( 71) GG 14 /29 (48) 23/29 (79) 21/ 29 (72) TG 19 / 31 ( 61) 26/ 31 (84) 23/ 31 (74) TT 10 9 /19 2 (57) 15 9 /19 2 (83) 13 3 /19 2 (69) TaqI BsmI ApaI** *The positivity of autoantibodies ... 252a N = 214 OR (95% CI)** TT 19 2 (76.2) 16 2 (75.7) 1. 00 (Reference) GT 31 (12 .3) 37 (17 .3) 0. 71 (0.42? ?1. 19) 0.23 GG 29 (11 .5) 15 (7.0) 1. 63 ((0.85–3 .15 ) 0 .15 19 2 (76.2) 16 2 (75.7) 1. 00 (Reference)

Ngày tải lên: 01/02/2020, 04:24

... BMC Pediatrics (2 014 ) 14 : 313 DOI 10 .11 86/s12887- 014 -0 313 -4 RESEARCH ARTICLE Open Access “You can’t just jump on a bike and go”: a qualitative study exploring parents’ perceptions of physical activity ... Road, Nottingham NG7 2TU, UK Received: 16 June 2 014 Accepted: 11 December 2 014 References About Diabetes [http://www.idf.org/about -diabetes] 17 19 20 21 22 23 24 25 Kiess W, Kapellen T, Siebler ... Res 2005, 13 :19 39? ?19 51 33 Herrman JW: Children's and young adolescents' voices: perceptions of the costs and rewards of diabetes and its treatment J Pediatr Nurs 2006, 21: 211 –2 21 34 Biddle SJ,

Ngày tải lên: 27/02/2020, 13:49

... offices Mean 14 .9 Target range 8 -18 8 -12 (n = 19 ) /13 ? ?18 (n = 33) ABCDEFHI Mean 10 .5 (S.D 4.2)/Target range 0 -16 ABCDEFGHI Target range 13 -18 13 -14 (45%), 15 ? ?16 (35%), 17 ? ?18 (20%) Waller et al [59] ... ( 41. 2%) / 5? ?10 (13 .7%) 11 school nurses helped students with CSII therapy Experience of children with T1D: 10 0% Survey of local schools across counties Number of children with T1D: 1- 4 ABCEH >10 ... diagnosis in childhood diabetes BMC Pediatr 2 011 , 11 :7 doi :10 .11 86 /14 71- 24 31- 14-228 Cite this article as: Edwards et al.: An ongoing struggle: a mixedmethod systematic review of interventions, barriers

Ngày tải lên: 02/03/2020, 15:25

... Confidence 18 35 14 -.04 -.28 - .14 23 02 - .13 38** Negativity - .19 - .15 - .16 - .12 14 08 - .14 - .10 13 01 ** Avoidance of parent -.09 - .13 - .19 -.08 12 30 -. 01 -. 01 08 -.02 Compliance 18 26* 33** 21 - .10 ... setting 18 ** ** 15 31 20 - .12 -.22 17 03 -. 01 00 31* * 23 05 -.20 - .14 20 01 - .10 24* Quality of instruction 17 12 09 07 - .13 01 00 03 -.05 03 Hostility -.35** - .11 -.45** -.08 -.02 28* - .18 - .12 16 ... Enthusiasm 14 12 08 - .17 -. 01 02 04 18 27* -.06 02 -.05 -.00 12 19 07 18 Experience of the session ** 33 * 25 * 29 Nieuwesteeg et al BMC Pediatrics 2 014 , 14 :14 5 http://www.biomedcentral.com /14 71- 24 31/ 14 /14 5

Ngày tải lên: 02/03/2020, 15:54

... Pediatrics 2 011 , 11 :55 http://www.biomedcentral.com /14 71- 24 31/ 11/ 55 Page of 12 b Diabetes outcomes directly related to patient management (i) Insulin delivery/number of injections/insulin types, (ii) ... February 2 011 Accepted: 14 June 2 011 Published: 14 June 2 011 References Court JM, Cameron FJ, Berg-Kelly K, Swift PG: Diabetes in adolescence Pediatr Diabetes 2009, 10 (Suppl 12 ) :18 5 -19 4 Bryden ... 2 011 , 11 :55 http://www.biomedcentral.com /14 71- 24 31/ 11/ 55 Background Type diabetes in adolescents is a challenge for the teenagers, their parents and the diabetes health care providers (HCPs) [1]

Ngày tải lên: 26/03/2020, 00:46

... 8.2 ± 0.4 12 .9 ± 1. 1 14 .4 ± 0.6 15 .0 ± 1. 2 Non-hormonal agents 19 2 ± (+22 41) 93 ± (+6 21) 11 3 ± (+685) 14 0 ± (+833) GppNHp, 10 −6 M 16 .7 ± 0.8 ( +10 4) 17 .9 ± 0.6 (+39) 17 .4 ± 0.9 (+ 21) 18 .3 ± 0.4 ... (+22) Forskolin, 10 −5 M 23.9 ± 1. 6 ( +19 1) 23.3 ± 0.5 (+ 81) 20.8 ± 1. 2 (+44) 21. 7 ± 1. 0 (+45) NaF, 10 −2 M Hormones Insulin, 10 −8 M 15 .9 ± 0.6 (+94) 15 .8 ± 0.3 (+22) 17 .3 ± 1. 1 (+20) 16 .3 ± 0.7 (+9) ... GppNHp 31. 2 ± 1. 7 (+280) 20.3 ± 0.9 (+57) 20.5 ± 0.5 (+42) 19 .5 ± 1. 2 (+30) Relaxin, 10 −8 M 18 .5 ± 1. 1 ( +12 6) 18 .8 ± 0.4 (+46) 18 .1 ± 0.5 (+26) 17 .8 ± 0.7 ( +19 ) Relaxin + GppNHp 38.2 ± 1. 8 (+366)

Ngày tải lên: 02/11/2022, 10:44

... (2 016 ) 14 :332 Page of 11 Table? ?1? ?? Clinical characteristics of? ?the patients Treated (n =? ?12 ) Not treated (n =? ?10 ) Age (years) [median; min–max] 12 .2; 8? ?16 11 .5; 7? ?16 BMI [median; min–max] 17 .1; 12 .5–23.5 ... Med (2 016 ) 14 :332 DOI 10 .11 86/s12967- 016 -10 90-7 Journal of Translational Medicine Open Access RESEARCH Factors affecting long‑term efficacy of? ?T regulatory cell‑based therapy in? ?type diabetes ... (fluorochrome/class/clone): antiCD3 (PacificBlue/IgG1/UCHT1), anti-CD4 (PerCP/ IgG1/RPA-T4), anti-CD25 (PE/IgG1/M-A2 51) , antiCD127 (FITC/IgG1/hIL-7R-M 21) and, anti-CD45RA (PE-Cy7/IgG1/L48) All of the antibodies were purchased

Ngày tải lên: 04/12/2022, 10:31

... visit the journal (http://dx.doi.org/ 10 .11 36/bmjopen-2 014 004806) Received January 2 014 Revised 29 June 2 014 Accepted July 2 014 For numbered affiliations see end of article Correspondence to Pernille ... systematic review with meta-analyses and trial sequential analyses of randomised clinical trials BMJ Open 2 014 ;4:e004806 doi :10 .11 36/bmjopen-2 014 004806 ▸ Prepublication history and additional material ... type diabetes mellitus: a systematic review with meta-analyses and trial sequential analyses of randomised clinical trials Pernille Kähler ,1 Berit Grevstad ,1 Thomas Almdal,2 Christian Gluud ,1, 3

Ngày tải lên: 19/03/2023, 15:18

... Science 2009, 4: 41 doi :10 .11 86 /17 48-5908-4- 41 Received: February 2009 Accepted: 22 July 2009 This article is available from: http://www.implementationscience.com/content/4 /1/ 41 © 2009 Goderis ... care of type diabetes patients: experiences of general practitioners participating to a quality improvement program Geert Goderis *1, Liesbeth Borgermans1, Chantal Mathieu2, Carine Van Den Broeke1, ... management of patients with diabetes [11 ] Optimal use of guidelines in general practice demands specific implementation strategies aiming at the reduction of barriers to high-quality care [12 ] However,

Ngày tải lên: 11/08/2014, 05:21

... dysfunction 10 15 20 25 30 Years of Diabetes Adapted from: UKPDS 33: Lancet 19 98; 352, 837-853 DeFronzo RA Diabetes 37:667, 19 88 Saltiel J Diabetes 45 :16 61- 1669, 19 96 Robertson RP Diabetes 43 :10 85, 19 94 ... for Diabetes -10 -5 Beta cell dysfunction 10 15 20 25 30 Years of Diabetes Adapted from: UKPDS 33: Lancet 19 98; 352, 837-853 DeFronzo RA Diabetes 37:667, 19 88 Saltiel J Diabetes 45 :16 61- 1669, 19 96 ... 45 :16 61- 1669, 19 96 Robertson RP Diabetes 43 :10 85, 19 94 Tokuyama Y Diabetes 44 :14 47, 19 95 Polonsky KS N Engl J Med 19 96;334:777 International Diabetes Center Insulin Use in Type Diabetes • Insulin utilized

Ngày tải lên: 12/08/2014, 20:58

... Diabetes 19 96; 45 :16 61- 1669 Peripheral Tissues (Muscle and Adipose) Natural History of Type Diabetes Glucose mmol/L Post-prandial glucose 20 17 14 11 Fasting glucose At risk for diabetes Beta-cell ... with type diabetes and over 60% of patients with type diabetes have retinopathy Proportion of patients with cardiovascular disease increases with duration of type diabetes 48% 29% 21% 24% 15 % ... Nephropathy  Over 40% of new cases of endstage renal disease (ESRD) are attributed to diabetes  In 20 01, 41, 312 people with diabetes began treatment for endstage renal disease  In 20 01, it cost $22.8

Ngày tải lên: 12/08/2014, 20:58

... effects HbA1c, hypoglycaemia, fear of hypogl HbA1c, hypoglycaemia, fear of hypogl .1 HbA1c, hypoglycaemia, fear of hypogl HbA1c HbA1c1, hypoglycaemia, fear of hypogl HbA1c1, hypoglycaemia, fear of hypogl ... subsequent years -0. 018 0.693 -0 .10 8 -0 .10 8 n/a n/a -0.0523 513 0.720 -0 .11 4 -0 .16 4 n/a n/a Stroke, subsequent years -0.040 0.800 -0 .11 4 -0 .16 4 n/a n/a Peripheral vascular disease -0.0 21 - - - n/a n/a ... al [ 21] used meta-analyses [5] for reduction of moderate and severe hypoglycaemia (both -18 %) combined with an HbA1c reduction of 0 .11 % points In the model of Brändle et al [25] a reduction of

Ngày tải lên: 13/08/2014, 11:22

... in type 2 diabetes mellitus: a systematic review. J Int Med 2004;256 :1- 14. 10 1 Diabetologia Croatica 39-3, 2 010 A. Marić / METFORMIN – MORE THAN ‘GOLD STANDARD’ IN THE TREATMENT OF TYPE 2 DIABETES ... activity in skeletal muscle of subjects with type 2 diabetes. Diabetes 2002; 51: 2074-20 81. 13 . DeFronzo R, Goodman A. Efficacy of metformin in patients with non-insulin-dependent diabetes mellitus. The ... entity? Diabetes Care 19 98; 21: 1659 -16 63. 22. Matthaei S, Bierwirth R, Fritsche A, Gallwitz B, Haring HU, Joost HG. Medical antihyperglycaemic treatment of diabetes mellitus type 2. Update of the

Ngày tải lên: 12/07/2015, 15:49

... ? ?1. 31) 1. 03 (0.93? ?1. 14) 1. 39 (1. 06 ? ?1. 81) 1. 13 (1. 06 ? ?1. 21) ϫ 10 Ϫ4 0. 612 0. 015 ϫ 10 Ϫ4 ϫ 10 Ϫ5 0.24 0. 011 ϫ 10 Ϫ5 0. 61 0.64 0.83 1. 10 (0.99 ? ?1. 23) 1. 22 (1. 09 ? ?1. 36) 1. 19 (0.87? ?1. 63) 1. 16 (1. 08 ... –5.46) 1. 16 (1. 07? ?1. 27) 0 .18 3 2.5 ϫ 10 Ϫ4 0.022 4 .1 ϫ 10 Ϫ4 0.075 3.7 ϫ 10 Ϫ5 0.023 ϫ 10 Ϫ5 0.65 0.68 0.94 0.69 0. 71 0.98 1. 21 (1. 09 ? ?1. 34) 1. 19 (1. 06 ? ?1. 34) 2.48 (1. 22–5.04) 1. 20 (1. 11? ? ?1. 30) ϫ 10 Ϫ4 ... 0.95 1. 39 (1. 08? ?1. 79) 1. 28 (0.85? ?1. 93) 2.32 (0.87–6.22) 1. 38 (1. 12? ?1. 70) 0. 011 0.245 0.094 0.002 0.63 0.66 0.92 1. 22 (0.94? ?1. 58) 1. 39 (0. 91? ??2 .11 ) 2 .16 (0.98–4.74) 1. 31 (1. 06? ?1. 61) 0 .13 5 0 .12 4

Ngày tải lên: 14/09/2015, 08:48

... complication of diabetes mellitus This case illustrates the importance of checking blood sugar levels of patients with non-healing corneal ulcers to rule out the possibility of undiagnosed diabetes ... (pCO2) of 44.7mmHg, and a partial pressure of oxygen (pO2) of 89.5 mmHg She was transferred to the care of the medical team and a diagnosis of type diabetes was made She was started on treatment ... Decreased penetration of anchoring fibrils into the diabetic stroma A morphometric analysis Arch Ophthalmol 19 89, 10 7 :15 20 -15 23 Sakamoto A, Sasaki H, Kitagawa K: Successful treatment of diabetic keratopathy...

Ngày tải lên: 10/08/2014, 22:20

... N Davis 73 10 1 11 5 Fueling the Athlete with Type Diabetes Carin Hume 15 1 Diabetes and Doping Richard I.G Holt 16 7 Synthesis of Best Practice Ian Gallen 19 3 10 The Athlete’s ... 19 94;267:E 411 – 21 130 Niijima A Glucose-sensitive afferent nerve fibres in the hepatic branch of the vagus nerve in the guinea-pig J Physiol 19 82;332: 315 –23 13 1 Smith D, Pernet A, Reid H, et al The role of ... Physiol 19 94;77 :15 37– 41 162 Tabata I, Ogita F, Miyachi M, Shibayama H Effect of low blood glucose on plasma CRF, ACTH, and cortisol during prolonged physical exercise J Appl Physiol 19 91; 71: 18 07 12 ...

Ngày tải lên: 14/03/2014, 09:20