epidemics autoimmunity and type 1 diabetes
Prevalence of Celiac disease in Turkish children with type 1 Diabetes Mellitus and their non-diabetic first-degree relatives pptx
... Offspring ( 913 ) Control ( 71) 10 .1 3.5 (32) 1. 3 (11 ) Jaeger et al 20 01 Germany (7) IgA-tTG, IgA &IgG-AGA Diabetic children (19 7) Parent, sibling and offspring (882) Control (15 0) 16 .8 7.3 4.6 ... al 20 01 Italy (14 ) Not et al 20 01 Italy (8) AEA; Biopsy Williams et al 20 01 UK (10 ) IgA-AEA; IgA-tTG 34 14 5.7 (28) 1. 9 (16 ) 0.25 (10 ) Diabetic children (433) Parent (8 71) and sibling (5 71) Control ... (69) Control (10 3) 0.05 (25) (10 ) (5) (3) Diabetic children and adult (4 91) Parent, sibling and offspring (824) Control (4000) p 5.7 (28) 1. 9 (16 ) 0.25 (10 )
Ngày tải lên: 05/03/2014, 12:20
báo cáo hóa học:" The cross-sectional associations between sense of coherence and diabetic microvascular complications, glycaemic control, and patients’ conceptions of type 1 diabetes" pot
... years NA 1. 10 (1. 07 - 1. 13) NA 1. 04 (1. 01 - 1. 06) NA 1. 12 (1. 09 - 1. 15) NA 1. 11 (1. 08 - 1. 13) 0.86 (0.64 - 1. 15) 0.99 (0.98 - 1. 01) 1. 00 (0.98 - 1. 01) Model Age at onset, years 1. 00 (0.94 - 1. 03) ... Gender, = male Model Diabetes duration, years 1. 07 (1. 05 - 1. 09) 1. 04 (1. 02 - 1. 06) 1. 11 (1. 09 - 1. 13) 1. 10 (1. 08 - 1. 12) 0.99 (0.98 - 1. 00) Age at onset, years 0.99 (0.97 - 1. 01) 0.95 (0.92 - 0.98) ... 0.99) 1. 00 (0.97 - 1. 03) 0.95 (0.92 - 0.98) Low SES, = yes 1. 50 (0.76 - 2.97) 1. 96 (0.95 - 4.05) 1. 14 (0.59 - 2. 21) 1. 39 (0.70 - 2.75) 0. 81 (0.54 - 1. 23) HbA1c 1. 37 (1. 12 - 1. 69) 1. 32 (1. 08 - 1. 61) ...
Ngày tải lên: 20/06/2014, 15:20
báo cáo hóa học:" Health related quality of life of Iranian children with type 1 diabetes: reliability and validity of the Persian version of the PedsQL Generic Core Scales and Diabetes Module" pot
... (10 0) 3/3 (10 0) 3/3 (10 0) 0.0 01- 0.42 0.26-0.74 0 .16 -0.62 0.22-0. 61 0.25-0.50 28/44 (64) 14 /16 (88) 21/ 28 (75) 12 /12 (10 0) 12 /12 (10 0) 11 3 0.43-0.65 0.58-0.83 0.54-0. 71 0.75-0.84 0.69-0.86 11 /11 ... 5/5 (10 0) 5/5 (10 0) 5/5 (10 0) 0.006-0.46 0.004-0.37 0.07-0.47 0.005-0.47 19 /24 (79) 15 /15 (10 0) 14 /15 (93) 13 /15 (87) 11 3 0.37-0.66 0.63-0.75 0.58-0.82 0.70-0.85 0.76-0.87 10 /11 (90. 91) 4/4 (10 0) ... 0.75-0.84 0.69-0.86 11 /11 (10 0) 4/4 (10 0) 7/7 (10 0) 3/3 (10 0) 3/3 (10 0) 0.002-0.42 0 .19 -0.57 0. 01- 0.54 0.20-0.50 0 .13 -0.49 39/44 (89) 14 /16 (88) 23/28 (82) 12 /12 (10 0) 12 /12 (10 0) a Number of correlation...
Ngày tải lên: 20/06/2014, 15:20
báo cáo hóa học:" Determinants of quality of life in adults with type 1 and type 2 diabetes" pdf
... Health and Quality of Life Outcomes 2 011 , 9 :11 5 http://www.hqlo.com/content/9 /1/ 115 Page of Table Characteristics of type and type diabetes samples Type diabetes (N = 490) Mean (SD) N (%) Type diabetes ... 1. 1 (1. 2) 1. 6 (1. 2) < 0.00 01 199 (40.6) 220 (19 .2) 13 8 (28.2) 329 (28.7) 85 (17 .3) 377 (32.9) 44 (9.0) 14 7 (12 .8) 20 (4 .1) 62 (5.4) (0.8) BMI (kg/m2) Lifestyle factors 12 (1. 0) 26.2 (4.6) 29 .1 ... (score 1- 5) 3.3 (0.6) 3.2 (0.6) 0 .11 21. 6 (12 .8) 11 .2 (12 .8) < 0.00 01 Medical factors Diabetes duration (years) Insulin use Yes Number of comorbidities (range 0-5) < 0.00 01 490 (10 0.0) 254 (22 .1) 1. 1...
Ngày tải lên: 20/06/2014, 15:20
TYPE 1 DIABETES – COMPLICATIONS, PATHOGENESIS, AND ALTERNATIVE TREATMENTS docx
... 3. 41 12.6 3.7 n 26 18 24 22 11 10 15 T1DM -DC 14 .4 (12 .4, 17 .9)ab 6(5.5, 8 .1) b 8.3 1. 4 ab 2.64 0.38 ab 64.4 10 .1 ab 43.3(42.6, 60.4) 10 6 (10 5, 16 1) 5.9 4 .14 b 17 .1 3 .1 n 20 20 20 20 20 17 19 ... 20 20 20 17 19 10 19 T1DM +DC 16 .4 (15 .1, 17 .6)a 10 .0(7.9, 12 .9) 10 .4 1. 4a 3.06 0.48a 71. 8 11 .6 78.2(49.5, 11 4.6) 12 7 (10 9, 15 2)a 10 .49 4.55a 17 .4 3.3a N 26 26 26 26 24 20 17 16 26 significant ... Pathogenesis, and Alternative Treatments 12 00 VCAM -1 (ng/ml) 11 00 10 00 900 800 700 600 10 11 12 HbA1cA (%) Fig The linear correlation between VCAM -1 and HbA1cA DD HbA1cA HbA1cP FAM (yrs.) Age (yrs.) 0.205...
Ngày tải lên: 27/06/2014, 17:20
TYPE 1 DIABETES – PATHOGENESIS, GENETICS AND IMMUNOTHERAPY ppt
... NCT00607230 NCT 011 156 21 NCT00279 318 NCT00333554 NCT 010 55080 NCT00607230 NCT0 014 1986 NCT0 013 1755 NCT00024 518 NCT00 711 503 NCT00645840 NCT00947427 NCT 013 193 31 NCT00279305 NCT00 214 214 NCT00 515 099 NCT00505375 ... and GAD2 (Bu et al., 19 92; Erlander et al., 19 91; Karlsen et al., 19 91) , Autoimmunity and Immunotherapy of Type Diabetes located on chromosome 2q 31. 1 and chromosome 10 p 11. 23, respectively (Bennett ... in Type Diabetes 16 1 Werner Gurr 83 VI Contents Chapter Part Chapter 10 Part Chapter 11 Part Type I Diabetes and the Role of Inflammatory-Related Cellular Signaling 18 3 Lloyd Jesse, Kelleher Andrew,...
Ngày tải lên: 27/06/2014, 17:20
Báo cáo khoa hoc:" The CTGF -945GC polymorphism is not associated with plasma CTGF and does not predict nephropathy or outcome in type 1 diabetes" pptx
... (10 0) Yes ( 31) (46) (23) 13 (10 0) No 89 (22) (14 ) 41 (10 0) 11 1 (29) 18 1 (48) 86 (23) 21 (38) 25 (45) (16 ) 55 (10 0) 10 5 (29) 17 6 (48) 83 (23) (0) (10 0) (0) (10 0) 12 6 (30) 200 (48) 92 (22) 0.9 91 ... (43) 25 (22) 11 5 (10 0) No Mortality Cardiovascular (CV) death 17 0 ( 51) 77 (23) 46 (47) 23 (23) 98 (10 0) 97 (28) 17 4 (50) 79 (22) 350 (10 0) Yes 14 (40) 15 (43) (17 ) 35 (10 0) 11 2 (29) 18 6 (48) 86 ... UAE (mg/24 h) 593 .1 (250.0 -15 19.5) 7.0 (4.0 -12 .0) p < 0.0 01 Plasma creatinine (μmol/l) 10 2 (82.0 -13 6.3) 79 (53- 81) p < 0.0 01 GFR (ml/min /1. 73 m2) 66 .1 ± 27.7 87.4 ± 14 .9 p < 0.0 01 ESRD (%male) 24...
Ngày tải lên: 11/08/2014, 07:21
báo cáo khoa học:" Determinants of quality of life in adults with type 1 and type 2 diabetes" ppsx
... 254 (22 .1) Number of comorbidities 1. 1 (1. 2) 1. 6 (1. 2) < 0.00 01 (range 0-5) 19 9 (40.6) 220 (19 .2) 13 8 (28.2) 329 (28.7) 85 (17 .3) 377 (32.9) 44 (9.0) 14 7 (12 .8) 20 (4 .1) 62 (5.4) (0.8) 12 (1. 0) ... -0.20 -0 .11 0 .13 Sig 0.00 01 0. 01 0.02
Ngày tải lên: 11/08/2014, 23:22
Báo cáo y học: "Cost-effectiveness of continuous glucose monitoring and intensive insulin therapy for type 1 diabetes" ppsx
... blindness 0 .10 1 0.057 0 .15 6 Hoerger et al [16 ,17 ] Diabetes with no complications to CHD 0.0 31 0. 018 0.048 Hoerger et al [16 ,17 ] Reference Subsequent LEA 0 .11 0 0.062 0 .16 9 Hoerger et al [16 ,17 ] Diabetes ... ADA [1] ESRD 36,370 26,377 47,708 ADA [1] LEA 50 ,15 0 36,5 41 65,798 ADA [1] Nephropathy 20 ,16 1 14 , 614 26,643 ADA [1] Neuropathy 25,075 18 ,226 33,004 ADA [1] Retinopathy 4,956 3,578 6,489 ADA [1] ... (397,782 - 550,598) 10 .289 (9. 615 - 10 .957) CGM and SMBG 494 ,13 5 (420,3 81 - 5 71, 6 31) 10 . 812 (9.894 - 11 .887) US $45,033/QALY *95% credible ranges based on the results from the 10 ,000 Monte Carlo...
Ngày tải lên: 13/08/2014, 11:22
IMPAIRED CARDIOVASCULAR RESPONSES TO GLUCAGON-LIKE PEPTIDE 1 IN METABOLIC SYNDROME AND TYPE 2 DIABETES MELLITUS
... Peptide and Systemic Glucose Regulation Glucagon-like Peptide and the Heart Glucagon-like Peptide 1: Mechanisms of Cardiac Action 10 GLP -1 as an Inotrope 12 GLP -1 and Myocardial ... either iv and/ or intracoronary GLP -1 (7-36), GLP -1 (9-36), and GLP-1R agonists all reduce infarct size and increase left ventricular function following an ischemic event ( 91- 93, 98 -10 3) The DPP-4 ... GLP-1R, the direct cardiac actions of GLP -1 are mediated by GLP -1 (9-36), but that the effects of intact GLP -1 (7-36) are GLP-1R dependent Such similar effects of GLP-1R agonists, GLP -1 (7-36) and...
Ngày tải lên: 24/08/2014, 12:16
Transplantation and improvement of mouse embryo progenitor derived insulin producing cells for type 1 diabetes therapy
... microcapsule……………… 11 0 4 .1. 3.3 The immune reaction after microcapsule transplantation …… 11 1 4 .1. 3.4 Behaviors of microencapsulated MEPI -1 cells.…………….… 11 2 4 .1. 4 Immaturity of encapsulated MEPI -1 cells…….………………… 11 3 ... cells…….………………… 11 3 4 .1. 5 Summary of transplantation of microencapsulated MEPI -1 cells…… .11 6 4.2 Restoration of MafA in MEPI -1 cells………………….……….……… 11 6 4.2 .1 Less-physical characteristics of MEPI -1 cells…………….……… 11 7 ... Insulin1, Insulin2, Pdx -1, NeuroD1, and Glut-2 (11 3) In addition, the expression of important -cell genes, e.g Nkx6 .1 and pyruvate carboxylase (PC), was regulated positively by MafA (11 1) MafA...
Ngày tải lên: 11/09/2015, 09:58
Tài liệu Báo cáo khoa học: Metabolic control of mitochondrial properties by adenine nucleotide translocator determines palmitoyl-CoA effects Implications for a mechanism linking obesity and type 2 diabetes pdf
... 0.030. 01 0.200.05 0.780 .12 ) 0.040. 01 0.260.02 ) 0.390.02 ) 0. 810 .19 0 .18 0 .10 0.790. 31 ) 0 .11 0.05 0.790 .13 * ) 0.780 .11 * ) 0.880.20 0.250.05 0.850.03 ) 0.050. 01 0 .11 0. 01 0.240.05 ) 1. 410 .04 0 .14 0.04* ... 0.080. 01 0.330 .11 ) 0. 010 .03 ) 0. 010 .00 0.090.27 3.7 91. 44 0.090. 01 4.2 81. 68 0.250.07 0.020.08 ) 0. 010 .00 0.050 .18 ) 1. 100 .18 0 .16 0. 01 ) 0.620 .11 0.620 .17 0.250.44 0 .17 0.08 0.020.38 ) 5.000.89 ) 0 .12 0. 01 ... 0.020.00 0 .11 0. 01 0.000. 01 ) 0.220.08 1. 270 .10 0 .14 0. 01 1.280.03 ) 0.030. 01 0 .13 0.03 0. 010 . 01 ) 0 .10 0.04 ) 0.750.08 0.260.04 ) 0.490.04 ) 0 .14 0.04 0 .15 0.03 ) 0.070 .10 ) 0.830.29 ) 3.320.43 ) 0 .18 0.03...
Ngày tải lên: 19/02/2014, 05:20
Long-term Exposure to Traffic-related Air Pollution and Type 2 Diabetes Prevalence in a Cross-sectional Screening-study in the Netherlands pdf
... 1, 795 (22%) 11 0 (18 %) 38 (18 %) 1, 685 (23%) 60-65 1, 446 (18 %) 12 2 (20%) 45 ( 21% ) 1, 324 (18 %) ≥ 65 2,024 (25%) 2 91 (47%) 10 2 (48%) 1, 733 (24%) BMI (kg·m-2) < 18 .5 51 (1% ) (1% ) (1% ) 48 (1% ) 18 .5-25.0 ... 14 0-220 1. 10 (0.87 -1. 39) 1. 12 (0.88 -1. 42) Q3: 74 -14 0 1. 22 (0.97 -1. 53) 1. 17 (0.93 -1. 48) Q4: 2-74 0.94 (0.74 -1. 19) 0.88 (0.70 -1. 13) Traffic flow at nearest main road (veh·24 hrs -1) Q1: 50 01- 58 71 reference ... 63- 516 reference reference Q2: 516 -680 1. 28 (1. 01- 1. 61) 1. 25 (0.99 -1. 59) Q3: 680-882 1. 15 (0. 91- 1.46) 1. 13 (0.89 -1. 44) Q4: 882-2007 1. 13 (0.89 -1. 44) 1. 09 (0.85 -1. 38) a Crude model: not adjusted...
Ngày tải lên: 06/03/2014, 19:20
Type 1 Diabetes Clinical Management of the Athlete potx
... adrenalectomised humans J Physiol 19 99; 519 (Pt 3): 911 – 21 112 Calles J, Cunningham JJ, Nelson L, et al Glucose turnover during recovery from intensive exercise Diabetes 19 83;32:734–8 11 3 Marliss EB, Simantirakis ... supply and demand Am J Physiol 19 94;267:E 411 – 21 130 Niijima A Glucose-sensitive afferent nerve fibres in the hepatic branch of the vagus nerve in the guinea-pig J Physiol 19 82;332: 315 –23 13 1 Smith ... Management of Type Diabetes for Sport and Exercise Alistair N Lumb Hypoglycemia and Hypoglycemia Unawareness During and Following Exercise Lisa M Younk and Stephen N Davis 73 10 1 11 5 Fueling...
Ngày tải lên: 14/03/2014, 09:20
báo cáo hóa học:" Is there a relationship between factor V Leiden and type 2 diabetes?" doc
... References 10 11 12 13 Fumelli P, Romagnoli F, Carlino G, Fumelli C, Boemi M: Diabetes mellitus and chronic heart failure Arch Gerontol Geriatr 19 96, 23:277-2 81 Kannel WB, McGee DL: Diabetes and cardiovascular ... baseline and two hours after OGTT between subjects with VTE and FVL compared to control group [93.55 ± 13 .57 mg\dl vs 91. 44 ± 13 .19 mg\dl (p: 0.68, not significant) and 10 4.90 ± 30.04 mg\dl vs 10 1.38 ... thrombosis and atherothrombosis http://www.translational-medicine.com/content/7 /1/ 52 14 15 16 Demirer AN, Alikasifoglu M, Tuncbilek E, Karakus S, Erbas T: Factor V Leiden mutation and type diabetes...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" Misinterpretation with norm-based scoring of health status in adults with type 1 diabetes" ppt
... 215 216 37 .13 (14 .28) 12 7 (58.8) 216 69 ( 31. 9) 13 1 (60.6) 13 (6.0) (1. 4) 216 16 (7.4) 42 (19 .4) 43 (19 .9) 41 (19 .0) 27 (12 .5) 40 (8.5) (3.2) 216 12 6 (58.3) 11 (5 .1) 18 (8.3) 30 (13 .9) 16 (7.4) 15 ... 20. 91 (12 .43) 12 .0 210 214 89 (42.2) 10 1 (47.9) 21 (10 .0) 19 5 (92.9) 4.0 (1. 0–5.0) 215 213 215 214 88 (40.7) 73 (33.8) 55 (22.5) 40 (18 .5) 216 216 216 216 216 82 (38.0) 56 (25.9) 44 (20.4) 34 (15 .7) ... 216 216 216 82 (38.0) 56 (25.9) 44 (20.4) 34 (15 .7) 11 8 (54.6) 53 (24.5) 25 (11 .6) 20 (9.3) 1. 0 35 ( 21. 2) 28 (16 .8) 19 (11 .4) 16 6 16 7 16 7 16 6 *n (%) unless otherwise specified † Medical conditions...
Ngày tải lên: 20/06/2014, 15:20
TYPE 1 DIABETES COMPLICATIONS ppt
... 7p12 .1 9p24.2 10 p15 .1 10p15 .1 10q22.3 10 q23. 31 11p15.5 12 p13. 31 12q13.3 12 q13.2 12 q24 .12 13 .32.3 14 q24 .1 14q32.2 14 q32.2 15 q14 15 q25 .1 16p13 .13 16 p 11. 2 16 q23 .1 17q12 17 q 21. 2 BACH2 CENPW TNFAIP3 ... RGS1 IL20-IL10-IL19 Several IFIH1 STAT4 CTLA4 CCR5 AC 111 003 .1 IL2-IL 21 2.05 0.89 0.84 -0.86 1. 10 0.82 0.85 1. 09 1. 13 6p 21 HLA 0.02-49.2 6q15 6q22.32 6q23.3 6q25.3 7p15.2 7p12 .1 9p24.2 10 p15 .1 10p15 .1 ... rs 313 8808 rs2070744 rs13293564 rs8330 61 No studies 14 10 10 2 Case/ Control 2 215 /2685 13 80 /13 08 13 80 /13 08 636/537 857/935 889/803 12 44/ 715 859/940 417 /240 1. 13 1. 12 0.79 1. 58 1. 54 1. 48 0.67 1. 53...
Ngày tải lên: 27/06/2014, 17:20
Báo cáo khoa học: "Oxcarbazepine as monotherapy of acute mania in insufficiently controlled type-1 diabetes mellitus: a case-report" pdf
... published All authors read and approved the final manuscript http://www.annals-general-psychiatry.com/content/6 /1/ 25 12 13 14 15 16 17 18 19 20 21 and improving the standard of care J Clin Psychopharmacol ... McCaque K: A double blind, randomized placebo-controlled trial of oxcarbazepine in the treatment of bipolar disorder in children and adolescents Am J Psychiatry 2006, 16 3 :11 79 -11 86 Suppes T, Kelly DI, ... References 10 11 McIntyre RS, Konarski JZ, Misener VL, Kennedy SH: Bipolar disorder and diabetes mellitus: epidemiology, etiology, and treatment implications Ann Clin Psychiatry 2005, 17 :83-93...
Ngày tải lên: 08/08/2014, 23:20
báo cáo khoa học: "A non-healing corneal ulcer as the presenting feature of type 1 diabetes mellitus: a case report" pps
... Arch Ophthalmol 19 89, 10 7 :15 20 -15 23 Sakamoto A, Sasaki H, Kitagawa K: Successful treatment of diabetic keratopathy with punctal occlusion Acta Ophthalmol Scand 2004, 82 :11 5 -11 7 Klocek MS, Sassani ... medical team and a diagnosis of type diabetes was made She was started on treatment with insulin Her corneal ulcer persisted and punctal plugs were inserted to increase the tear film and facilitate ... changed to topical g chloramphenicol 1% four times each day and g prednisolone 0.5% four times each day once her microbiology and virology results were negative A bandage contact lens was inserted...
Ngày tải lên: 10/08/2014, 22:20