engineering of integrin specific biomimetic surfaces to control cell adhesion and function
Tài liệu Global action plan to control the spread and impact of antimicrobial resistance in Neisseria gonorrho pdf
Ngày tải lên :
18/02/2014, 15:20
... modelling should be used to: • study the costing of aspects of AMR and control of the impact of AMR, in order to transfer the knowledge and capacities from one setting to another and better plan for ... to play in understanding and controlling the threat of untreatable gonorrhoea Additional initiatives are needed in the areas of laboratory, operational and therapeutic responses to existing and ... identification of factors that contribute to the emergence and spread of AMR in N. gonorrhoeae • • • • newer molecular methods for monitoring and detecting AMR • correlation of genetic phenotypes to MIC and...
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Báo cáo Y học: Matrilysin (matrix metalloprotease-7) cleaves membrane-bound annexin II and enhances binding of tissue-type plasminogen activator to cancer cell surfaces docx
Ngày tải lên :
17/03/2014, 17:20
... is found on cell surfaces of many types of cultured cells [19–21] Indeed, flow cytometric analysis revealed the existence of annexin II on cell surfaces of WiDr cells (data not shown) To examine ... annexin II with the cell surface receptors Binding of tPA to surfaces of matrilysin-treated cells It has been shown that tPA binds to annexin II on the surfaces of human endothelial cells [18,25] In ... endothelial cells [14] Many studies have shown that extracellular annexin II is involved in the regulation of a variety of cellular processes, including pericellular proteolysis, cell cell or cell ECM adhesion, ...
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Series in Electrical and Computer Engineering - Vol 2 - A Mathematical Introduction to Control Theory - S. Engelberg
Ngày tải lên :
01/07/2015, 10:13
... transform and the poles of the fraction, we find that the rate of growth of the inverse Laplace transform is a function of the real part of the pole 6/(2a) and the frequency of the oscillations is controlled ... pillars of support Without my father's love and appreciation of mathematics and science and my mother's love of good writing I would neither have desired to nor been suited to write a book of this ... Laplace transform of f(t) It is customary to use lower-case letters for functions of time, t, and to use the same letter—but in its upper-case form—for the Laplace transform of the function; throughout...
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Báo cáo sinh học: "Bisphosphonate-associated osteonecrosis of the jaw is linked to suppressed TGFb1-signaling and increased Galectin-3 expression: A histological study on biopsies" pot
Ngày tải lên :
18/06/2014, 19:20
... percentage of expressing cells (ratio of positively stained cells to the total number of cells per visual field, multiplied by 100) Cells of fibroblast lineage, including perisoteal progenitor cells, ... regulation of epithelial and bone differentiation and Page of 11 plays a pivotal role in inflammatory responses and fibrotic tissue remodeling; it has been shown to inhibit the activation of cytokines ... stimulation of progenitor cells and enhance the ongoing suppression of connective progenitor cell proliferation {Riddle, 2009 #4005} The clinical observation of painless, exposed jaw bone and non-reactive...
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o cáo hóa học:" Bisphosphonate-associated osteonecrosis of the jaw is linked to suppressed TGFb1-signaling and increased " potx
Ngày tải lên :
20/06/2014, 04:20
... percentage of expressing cells (ratio of positively stained cells to the total number of cells per visual field, multiplied by 100) Cells of fibroblast lineage, including perisoteal progenitor cells, ... regulation of epithelial and bone differentiation and Page of 11 plays a pivotal role in inflammatory responses and fibrotic tissue remodeling; it has been shown to inhibit the activation of cytokines ... stimulation of progenitor cells and enhance the ongoing suppression of connective progenitor cell proliferation {Riddle, 2009 #4005} The clinical observation of painless, exposed jaw bone and non-reactive...
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Báo cáo y học: " Relatives Education And Coping Toolkit - REACT. Study protocol of a randomised controlled trial to assess the feasibility and effectiveness of a supported self management package for relatives of people with recent onset psychosis" pdf
Ngày tải lên :
11/08/2014, 15:22
... contributed to design of the intervention, recruits and assesses participants, and manages the process of randomisation; VP contributed to the design of the intervention and management of the project; ... Education And Coping Toolkit - REACT Study protocol of a randomised controlled trial to assess the feasibility and effectiveness of a supported self management package for relatives of people ... of the intervention for relatives, exactly how they use the intervention, Page of and their preferences for how this should be delivered, including format of the toolkit and type and amount of...
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Báo cáo y học: " Effect of oat bran on time to exhaustion, glycogen content and serum cytokine profile following exhaustive exercise" pdf
Ngày tải lên :
11/08/2014, 23:21
... Therefore, the aim of this study was to evaluate the effect of oat bran supplementation on time to exhaustion, glycogen stores and cytokines profile in rats submitted to training Materials and methods ... polysaccharide binding to the lectin site of neutrophil or natural killer cell complement receptor type (CD11b/CD18) generates a primed state of the receptor capable of mediating cytotoxicity of iC3b-opsonized ... 3) Discussion The aim of this study was to evaluate the effect of oat bran supplementation on time to exhaustion, glycogen stores and cytokines profile in rats submitted to training The animals...
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Cellular and molecular control of skeleton formation in fish insights from osteoblast ablation and functional characterization of lrp5 and SOst
Ngày tải lên :
10/09/2015, 08:43
... osteocyte specific activation of a gain of function variant of Lrp5 leads to high bone mass phenotype in a cell autonomous fashion, thus reverting the attention of Lrp5 function back on bone cells ... into the pDrive cloning vector (Qiagen) by adding 100 ng of DNA to 5μl of Ligation Master Mix and 1μl of vector (50 ng) and adjusting the total volume by addition of H20 to 10μl After incubation ... 3.D; and Renn and Winkler, 2009) Taken together, these findings support that loss of CFP fluorescence is a consequence of apoptosis due to cytotoxic properties of Ntr catalyzed reduction of Mtz...
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hemotherapy induces intra tumoral expression of chemokines in cutaneous melanoma, favoring t cell infiltration and tumor control
Ngày tải lên :
10/09/2015, 15:49
... inhibitory and activating signals (Lanier, 2005) 1.2.1.3 NK cells inhibitory and activating receptors NK cells make use of a large repertoire of germline-encoded inhibitory and activating receptors ... mechanisms of NK cell cytotoxicity have been described Firstly, activated NK cells can release cytotoxic granules containing perforin and granzymes, leading to target cells apoptosis In addition to the ... leading to strengthened adhesion to immobilized integrin ligands The binding of β2 -integrin, αLβ2 (or leukocytefunction associated antigen-1, LFA1) to their endothelial ligands, ICAM1 and ICAM2...
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Tissue engineering of an osteochondral transplant by using a cell scaffold construct
Ngày tải lên :
14/09/2015, 14:07
... degree of Doctorate of Philosophy in the Graduate Program of Bioengineering (NUS Graduate School for Integrative Sciences and Engineering) at the National University of Singapore No part of this ... researchers and even the general public Tissue engineering can be defined as the endeavor to promote the regeneration of a specific tissue or organ through the use of biomaterials, cells and growth factors, ... omission of exogeneous cells could lead to unfavorable outcomes [31] In an osteochondral construct, the candidate cells can be differentiated cells (osteoblast and chondrocytes) or progenitor cells...
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Báo cáo hóa học: " Effects of pegylated G-CSF on immune cell number and function in patients with gynecological malignancies" doc
Ngày tải lên :
18/06/2014, 16:20
... nodes of NOD mice, with the likely aim to restrain the proliferation and function of diabetogenic T cells [31] It remains to be determined whether Treg recirculation and/ or recruitment to sites of ... system’s ability to control disease progression IL-12, a prototype member of a family of IL-12-related cytokines that includes IL-23 and IL-27, is an instigator of Th1 immune responses and possesses ... growth factor (TGF)-b1, and to suppress T -cell proliferation in a cytokine-dependent manner [6] Furthermore, G-CSF induces the release of hepatocyte growth factor (HGF) [7], a pleiotropic cytokine...
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Báo cáo y học: "Discrepancy between the in vitro and in vivo effects of murine mesenchymal stem cells on T-cell proliferation and collagen-induced arthritis" doc
Ngày tải lên :
12/08/2014, 11:23
... with IL-17 to upregulate expression of PD-L1, iNOS, and COX-2 in MSCs, making these molecules candidate mediators of T -cell inhibition The involvement of iNOS and COX-2 in inhibition of T -cell proliferation ... CIA induction and evaluation and to analysis of T -cell proliferation PM contributed to the design of the study and to manuscript preparation All authors contributed to interpretation of the data ... PBS-treated control animals To verify whether the failure of MSCs to affect clinical scores of arthritis was also reflected in cellular and humoral autoimmune responses, DTH and total anti-CII...
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Báo cáo y học: "Survivors of war in the Northern Kosovo (II): baseline clinical and functional assessment and lasting effects on the health of a vulnerable population" ppsx
Ngày tải lên :
13/08/2014, 14:20
... effects of other variables and confounding factors The ShapiroWilk test and skewness and kurtosis tests were used to determine the normal distribution and homogeneity of variance of height, weight and ... either hand; two had no strength in the right hand, and one had none in the left hand Only out of 62 male and 10 out of 63 female victims had handgrip strength for the dominant hand equal to or ... Good and bad effects of being in organisations One of the important aims of our study was to identify factors that help or hinder the reintegration of victims of massive violence and the return to...
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Báo cáo sinh học: "Genome-wide mapping of Quantitative Trait Loci for fatness, fat cell characteristics and fat metabolism in three porcine F2 crosses" pptx
Ngày tải lên :
14/08/2014, 13:21
... Relative number of fat cells in the class of about 73 μm diameter % FN92 Relative number of fat cells in the class of about 92 μm diameter % FN114 Relative number of fat cells in the class of about ... Relative number of fat cells in the class of about 146 μm diameter Relative number of fat cells in the class of about 183 μm diameter % % FNCM Relative number of fat cells with medium cell sizes (FN73 ... volume of fat cells in the class of about 73 μm diameter % FV92 Relative volume of fat cells in the class of about 92 μm diameter % FV114 FV146 Relative volume of fat cells in the class of about...
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Study of human nasal epithelial stem or progenitor cell growth and differentiation in an in vitro system
Ngày tải lên :
09/09/2015, 11:29
... types of cell: basal cells, goblet cells and ciliated or non-ciliated columnar cells Basal cells may involve into the epithelial repair after injury and other types of cells are more related to ... survived and more than 90% of cells proved to have properties of epithelial stem or progenitor cells in a chemical-defined medium Meanwhile, these cells successfully differentiated into functional cells ... expressed on the cytoskeleton of cilia) On the other hand, non-ciliated columnar cells are usually classified as secretory cells and rarely studied in upper airway due to the absence of specific markers...
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Modeling and simulation of cell adhesion and detachment
Ngày tải lên :
10/09/2015, 15:48
... Interaction between Receptors and Ligands Cell adhesion is mediated by specific interactions between receptors and ligands The kinetics and mechanics of cell adhesion are coupled, because specific interaction ... Variation of receptor density caused by diffusion of the receptors on the cell surface Receptors can diffuse from D to B due to the attraction of the nonspecific tractions and from E to D due to the ... migration, and cell- cell and cell- ECM adhesions In the case of adhesion, the lateral mobility of receptors determines the speed at which receptors move towards their corresponding ligands, the...
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Use of an extension of the park's transformation to determine control laws applied to a non sinusoidal permanent magnet synchronous motor
Ngày tải lên :
03/01/2014, 19:50
... vector control ia i ia ref Figure 6a: Scheme for "dq" vector control 'Tested "dq" vector control includes compensations of backelectromotive forces but not take into account the coupling of d and ... vector control: torque and currents versus time for a controller wth slow response time (1 ms) Torque I T ref t t ib ia / ia ref ic t ib I ib ref Figure 5c: "abc" frame vector control: torque and ... vector control to 36 We have tried to impose theses computed phases currents (figure sa) and have note the results with two different controllers To get best performance when response time has to...
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Tài liệu Báo cáo khoa học: Enhanced thermostability of methyl parathion hydrolase from Ochrobactrum sp. M231 by rational engineering of a glycine to proline mutation pdf
Ngày tải lên :
15/02/2014, 01:20
... mutant (G194P ⁄ G198P) was similar to that of the WT enzyme and between those of G194P and G198P Thermostability of WT and mutant enzymes The thermostability of the WT and mutant enzymes was determined ... whereas the T50 of G198P was lower than that of the WT enzyme The T50 of the double point mutant (G194P ⁄ G198P) was similar to that of the WT enzyme and between those of G194P and G198P To further ... C & Mulchandani A (2010) Cotranslocation of methyl parathion hydrolase to the periplasm and of organophosphorus hydrolase to the cell surface of Escherichia coli by the Tat pathway and ice nucleation...
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![Tài liệu Báo cáo khoa học: Specific targeting of a DNA-alkylating reagent to mitochondria Synthesis and characterization of [4-((11aS)-7-methoxy-1,2,3,11a-tetrahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-on-8-oxy)butyl]-triphenylphosphonium iodide doc](https://media.store123doc.com/images/document/14/br/vp/medium_vpv1392870032.jpg)
Tài liệu Báo cáo khoa học: Specific targeting of a DNA-alkylating reagent to mitochondria Synthesis and characterization of [4-((11aS)-7-methoxy-1,2,3,11a-tetrahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-on-8-oxy)butyl]-triphenylphosphonium iodide doc
Ngày tải lên :
20/02/2014, 11:20
... within the mitochondria due to the mitochondrial membrane potential [11] From the known plasma and mitochondrial membrane potentials and the cell and mitochondrial volumes of 143B cells [48] we ... alkylation of mtDNA The uptake of mitoDC-81 into cells driven by the plasma membrane potential (Dwp) followed by the further accumulation of mitoDC-81 into mitochondria driven by the mitochondrial ... every 61.5 mV of membrane potential This leads to a millimolar concentration of mitoDC-81 within mitochondria on incubation of cells with high nanomolar to micromolar concentrations of mitoDC-81 This...
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