... for building energy standards The practice of building energy standard for energy saving and sustainable energy efficient design in building is a complex system, involving many different interest ... sustainable issues and provide economic incentives for sustainable development in building Recommended sustainable energy efficient building initiatives Sustainable energy efficient building initiatives, ... achieving sustainable energy efficiency in building through the implementation of building energy standards ; is to start with the implementing the following sustainable energy efficient building initiatives:...
... resources indicates the human effort involved in designing and maintaining the automated machines The ranking assigned for human resources may be higher during manufacturing, installation and maintenance ... are low due to direct chemical looping being in its infancy in the energy conversion industry [42] This process is widely used in steel manufacturing but not in the hydrogen production sector ... Storage 70 Drying 60 Crushing/Grinding 50 In system transporting 40 Mixing of fuels, carrier gas Fuel handling processes 30 20 10 TECHNO‐CENTRIC SOCIO‐CENTRIC Figure Sustainability indices (%)...
... department coordinator and vicecoordinator of post-graduation program in hydraulic engineer and sanitation Dr Reis has large experience in civil engineering with emphasis in Hydraulics, acting mainly at ... micro turbines integrated installed within the conveyance system to power the system for pumping or turbine the flow between reservoirs, and to sell surplus energy [6] An example of a hybrid energy ... the electricity supply infrastructure [1] The concern with the consumption of energyin water supply systems is increasingly inducing the managers of these systems in seeking optimal solutions...
... (2008) Mapping alpha-helical induced folding within the intrinsically disordered C-terminal domain of the measles virus nucleoprotein by site-directed spin-labeling EPR spectroscopy Proteins 73, ... (2005) The intrinsically disordered C-terminal domain of the measles virus nucleoprotein interacts with the C-terminal domain of the phosphoprotein via two distinct sites and remains predominantly ... for predicting protein binding regions in disordered proteins Bioinformatics 25, 27452746 41 Uversky VN (2002) Natively unfolded proteins: a point where biology waits for physics Protein Sci 11,...
... persistent increase in intracellular ROS generation after oridonin exposure NAC pretreatment resulted in the complete inhibition of oridonin-induced apoptosis, indicating that oridonin-induced apoptosis ... up-regulated p38 activation in oridonin-induced L929 cells Interestingly, we found that inhibition of p38 decreased oridonin-induced NF-jB activation, indicating that oridonin-induced p38 activation ... LC3-II both increased with time after oridonin administration These results indicate that oridonin induced autophagy in L929 cells Inhibition of autophagy up-regulates apoptosis in oridonin-induced...
... Parkin, PINK1, DJ-1 and HtrA2 activity remains to be determined Parkin can be phosphorylated by a number of kinases including casein kinase 1, protein kinase A, protein kinase C [86] and cyclin-dependant ... Interestingly, susceptibility to rotenone toxicity is increased in neurons from Parkin-null mice [39] PINK1 suppression using small interfering RNA decreased cell viability and significantly increased ... that PINK1 maintains neuronal survival by protecting neurons against oxidative stress [79] In mammalian cell culture, PINK1 protects against oxidative stress-induced cell death by suppressing cytochrome...
... phospholipase A2 participates in ER stress-induced INS-1 insulinoma cell apoptosis by promoting ceramide generation via hydrolysis of sphingomyelins by neutral sphingomyelinase Biochemistry 46, 10170– ... post-lysosomal destinations Cells from NPC subjects show a decrease in acid sphingomyelinase activity, leading to the accumulation of sphingomyelin [27] Because one of the pathways for ceramide recycling is ... are caused by mutations in the NPC1 gene, referred to as type C1 This gene encodes a putative integral membrane protein containing motifs consistent with a role in the intracellular transport...
... measure threonine and cystathionine ux Threonine ux was measured using puried threonine deaminase and commercial lactate dehydrogenase Threonine deaminase transforms threonine into oxobutyrate ... branches in independent reactions containing either threonine deaminase or cystathionine b-lyase mixed with homoserine kinase, CGS, TS and lactate dehydrogenase Experiments were carried out in a ... synthesis of lysine, methionine and threonine Threonine is a precursor for isoleucine synthesis and methionine is a direct precursor of S-adenosylmethionine (AdoMet) In plants, the branching between...
... management training into the existing corporate training matrix to ensure that energy training is regularly covered Generic team training, e.g in conflict management, problem solving, should also ... GUIDE TO ENERGY EFFICIENCY OPPORTUNITIES IN THE CANADIAN BREWING INDUSTRY ENERGY AUDITING ENERGY AUDITING 3.0 ENERGY AUDITING 26 Why have energy audits?1 An energy conservation project, yielding a ... for increased uptake inenergy efficiency practices within the Canadian brewing industry and this updated Guide should help a practicing brewer or any industry that is interested in conserving energy...
... analyzed with a motif searching program to identify binding sites of transcription factors Consensus binding sites are underlined, the Nrl-binding site is printed in bold, and the transcription ... sharp increase in Fig Nrl directly binds to the Ppp2r5c promoter consensus element in vitro EMSA showing the binding of Nrl to NRE sites in the rhodopsin and Ppp2r5c promoters Lanes are as indicated ... patterns of binding of Nrl to the rhodopsin promoter (Fig 4C,D) The mRNA transcript levels of Ppp2r5c and rhodopsin in mouse retina corresponded to the observed increase in Nrl binding affinity...
... a single quinol-binding site However, the technique used to determine binding sites of quinols, inhibition by HOQNO (a structural analogue of menaquinone), did not allow them to see the binding ... suggesting the existence of two menadiol binding sites in the enzyme, one with higher affinity than the other, as well as inhibition data indicating the possibility of more than one menaquinol binding ... the binding site of the menaquinols, but for technical reasons it cannot reveal the site for the ubiquinols, because HOQNO does not inhibit binding of the ubiquinols Fig Variation of reducing...
... Oncomodulin a 1ivpA Adenovirus fibre STNV coat protein Pseudoazurin Transthyretin Picornavirus Cellular retinoicacid-binding protein (HIV-2) protease b 1lbbA 2sas Calcium-binding protein Parvalbumin ... Fasciculin Plasminogen small small small 1reiA Phosphatidylinositol 3-kinase a-Spectrin, SH3 domain Signal transduction protein Seed storage protein s vicillin Immunoglobulin Diphtheria toxin NADH ... transduction protein Ferredoxin II, Peptostreptococcus Ferredoxin II, Desulfovibrio gigas Ribonuclease A c-src Tyrosine kinase Prion protein domain MHC class II p41 invariantchain fragment Methylamine dehydrogenase...
... calmodulin and PtdIns3K In guinea pig neutrophils, it has been demonstrated that inhibition of calmodulin results in inhibition of Rac and p21 activated kinases [50] Involvement of Rac in ROS ... switch of a5b1 integrin in CHO cells, suggesting also a role for Ca2+/calmodulin-dependent molecules in regulating the affinity state of integrins on neutrophils [48] Although PtdIns3K has been ... measured by analyzing annexin V-fluorescein isothiocyanate-binding (Bender Medsystems; Vienna, Austria) In short, neutrophils were resuspended in Hepes buffered RPMI containing 8% serum (Hyclone)...
... domains of cognate proteins [31,44] Indeed, PRD of Caskin1 contains several consensus SH3 binding sites, and we postulate that it is involved in multiple interactions with other PSD proteinsIn ... of these proteinsIn this article, we focus on three classes of complex-forming proteins of related function, also including anchor and docking proteins The prototype for anchor proteins is the ... becomes tyrosine phosphorylated on multiple sites that can interact with signalling proteins containing SH2 domains Insulin receptor substrate 1, for example, contains an N-terminal Pleckstrin homology...
... membrane proteins involved in secretion of haemolysins or adhesins in various Gramnegative pathogens, proteins of the endosymbiotic organelles belong to the increasing list of such proteins [53] ... C-terminus of the investigated sequences (A) The positioning of the starting amino acid of motif in relation to the C-terminus and (B) the positioning of the starting amino acid of motif in relation ... polypeptidetransporting proteins and that it is involved in pore formation The possible function is discussed Results Motifs in b-barrel-shaped polypeptide-transporting proteins b-barrel type proteins are...
... f, (inset in i), m, (inset in n), o, (inset in o), p, (inset in r)) 20 µm; (e, g, h, i, q, r) 50 µm Local injury to the hippocampus via saline injection produces a strong induction of activin-βA ... downstream adaptor proteins like the insulin receptor substrate proteins (IRS-1-4) [5] Through phosphor‐ ylation, IRS proteins bind to SRC-homology-2 (SH-2) domain-containing proteins like SRC, SRC ... compared to the uninjured brain 15 16 Trends in Cell Signaling Pathwaysin Neuronal Fate Decision A major component of the brain post-injury in comparison to the uninjured brain is the inflammatory...
... to produce and maintain an inducing quantity of acetaldehyde in the presence of ethylacetate Induction of the alc system in an alcA-independent manner could be explained presuming that acetaldehyde ... Lenouvel, F & Felenbok, B (1999) A single amino acid, outside the AlcR zinc binuclear cluster, is involved in DNA binding and in transcriptional regulation of the alc genes in Aspergillus nidulans Mol ... The amino acids L-proline and L-arginine not induce the alc system Northern blot analysis was done in gpdA::alcR, a strain constitutively overexpressing the alcR gene (alcR*) The prnD (L-proline...
... operating cost savings Finally, each mill area is discussed in detail in the PAPTAC short course, “Improving Energy Efficiency in the Pulp and Paper Industry.” Energy Purchasing Strategies Energy ... savings by optimizing energy usage in newsprint mills Possible savings in fossil fuels for an individual mill can be estimated in the same way as for kraft mills Possible savings in electricity ... with higher-quality mechanical printing paper grades requiring higher energy Though there are new processes for reducing refining energy somewhat [8], consistent industrial performance has not...