endpoint analysis of both models

Báo cáo y học: "Free radical theory of autoimmunity" potx

Báo cáo y học: "Free radical theory of autoimmunity" potx

Ngày tải lên : 13/08/2014, 23:20
... the host because of one or more of the following factors: reduced absorption of the specific drug; delayed/expedited rate of metabolism by the specific organ involved; loss of drug accumulation ... cells); elimination of target (e.g induction of alternative pathway) or alteration of target's affinity for the drug; overproduction of target (e.g gene amplification); accumulation of metabolite antagonistic ... and/or lack of delivery of a given drug to the tumor site (owing to size or location of the tumor, or low absorption rate of a high molecular weight drug); and non- specific interactions of drugs...
  • 16
  • 318
  • 0
Báo cáo Y học: Role of conserved residues within helices IV and VIII of the oxaloacetate decarboxylase b subunit in the energy coupling mechanism of the Na+ pump ppt

Báo cáo Y học: Role of conserved residues within helices IV and VIII of the oxaloacetate decarboxylase b subunit in the energy coupling mechanism of the Na+ pump ppt

Ngày tải lên : 08/03/2014, 23:20
... grow in presence of 360 mM NaCl because both Na+/H+ antiporters are lacking [13] After transformation of E coli EP432 with either of the mutant plasmids, growth in the presence of 360 mM NaCl was ... shown in Fig Kinetic analysis of the wild-type enzyme We have reported recently that the initial velocity of oxaloacetate decarboxylation has sigmoidal dependence on Labeling of oxaloacetate decarboxylase ... a negative control, E coli EP432 harbouring pSK was used The synthesis of an active Fig SDS/PAGE analysis of a selection of mutant oxaloacetate decarboxylases synthesized in E coli and purified...
  • 8
  • 508
  • 0
Báo cáo khoa học: The role of Tyr71 in Streptomyces trypsin on the recognition mechanism of structural protein substrates ppt

Báo cáo khoa học: The role of Tyr71 in Streptomyces trypsin on the recognition mechanism of structural protein substrates ppt

Ngày tải lên : 16/03/2014, 00:20
... activity of chimera F towards both types of collagen was the highest among the chimeras and higher than that of parental SOT and SGT These specific activities were used to calculate the ratio of the ... the binding of the acidic surface of collagens to the basic surface charged region of the enzyme Studies are underway using surface plasmon resonance analysis to determine the role of residue ... recombination sites of chimeras A–H are shown in (B) The primary structures of SOT (upper) and SGT (lower) are shown The recombination sites of the chimeras are boxed The names of the chimeras are...
  • 13
  • 469
  • 0
Báo cáo khoa học: Role of peroxidase inhibition by insulin in the bovine thyroid cell proliferation mechanism pdf

Báo cáo khoa học: Role of peroxidase inhibition by insulin in the bovine thyroid cell proliferation mechanism pdf

Ngày tải lên : 30/03/2014, 14:20
... the HPLC analysis of the semipurified fraction F4 demonstrating the absence of inhibitory effect on TPO in the protein fractions (data not shown) The absence of lipids in the structure of the peroxidase ... means of a cytosolic inhibitor as mediator of its action To rule out the possibility that the cytosolic inhibition of peroxidase, instead of being specific for the enzyme activity, could be part of ... (1999) Presence of a soluble inhibitor of thyroid iodination in primary cultures of thyroid cells Eur J Endocrinol 141, 55–60 Larner, J (1983) Mediators of postreceptor action of insulin Am J...
  • 8
  • 440
  • 0
Báo cáo y học: " The role of the N-terminal segment of CCR5 in HIV-1 Env-mediated membrane fusion and the mechanism of virus adaptation to CCR5 lacking this segment" ppt

Báo cáo y học: " The role of the N-terminal segment of CCR5 in HIV-1 Env-mediated membrane fusion and the mechanism of virus adaptation to CCR5 lacking this segment" ppt

Ngày tải lên : 13/08/2014, 05:22
... apparent "on-rate" of CCR5 binding The kinetics of formation of ternary complexes at 18°C was evaluated by measuring the rate of acquisition of resistance to a high concentration of Sch-C added after ... presence of varied concentrations of S22 led to efficient dye redistribution (Fig 7A) The extent of JRFL Env-induced fusion with CCR5(∆18) cells in the presence of 200 µM of S22 reached 50–60% of fusion ... capable of triggering the Env(NYP) gp41 refolding but not refolding of Env(wt) Figure Inhibition of cell-cell fusion by the C34 peptide Inhibition of cell-cell fusion by the C34 peptide The extent of...
  • 14
  • 305
  • 0
The Role of Power

The Role of Power

Ngày tải lên : 22/08/2012, 22:07
...  Role of Power  Rules for Using Power Role of Power  Power defined:  • Ability or official capacity to exercise control;  authority • Ability to influence or control others  Sources of Power ... Find the Soft Spot  Encourage others to open up • Gain disclosure of something private or  personal about your counterpart • Expression of trust  Identify true motivations and sources  of objections ... Relationship between power &  dependence • Power A, B = Dependence B, A • Power of person A over B is equal to the  dependence of person B on A Rule #6: Power of Who You Know It’s not what you know but who you know...
  • 20
  • 590
  • 0
 Circuit theory of finance and the role of incentives in financial sector reform

Circuit theory of finance and the role of incentives in financial sector reform

Ngày tải lên : 24/10/2012, 09:33
... efficiently, the reputational capital of an agent must equal the present value of the stream of future profits, or franchise value, of her business The concept of reputational capital is meaningful ... dimensions of finance and by involving agents’interactions, CTF overcomes the analytical shortcomings of “representative agent” models of intertemporal resource allocation, as well as those of the ... institutions on the basis of the implicit guarantee of (perceived) unlimited solvency of the public sector Also, the large share of public spending on aggregate output stabilizes the flow of funds that firms...
  • 55
  • 665
  • 0
Facts of Vietnam Freight forwarding industry and the role of Vietnam Freight Forwarders Association (VIFFAS) to the industry in international economic integration processhelpful to Oristar.doc

Facts of Vietnam Freight forwarding industry and the role of Vietnam Freight Forwarders Association (VIFFAS) to the industry in international economic integration processhelpful to Oristar.doc

Ngày tải lên : 27/10/2012, 16:42
... of Foreign Trade 2.3 Faculty of Business English Functions & Main Activities of VIFFAS VIFFAS has the function of socio-professional associated organization of the enterprises, irrespective of ... lack of regulations and an incomplete legal framework on activities of freight forwarders, the quality of services has not met the requirements of the industry's development yet A lack of decrees ... developing and increasing the quality of trade services of the Ministry of Trade and the Ministry of Transport Being the intermediary between enterprises and Government’s offices, VIFFAS has always made...
  • 31
  • 1.2K
  • 21
Báo cáo y học: " Role of Dietary Soy Protein in Obesity"

Báo cáo y học: " Role of Dietary Soy Protein in Obesity"

Ngày tải lên : 31/10/2012, 14:59
... concentrations of isoflavones The amount of isoflavones in soybeans varies depending upon the type of soybean, geographic area of cultivation, and harvest years of soybeans [33-36] In addition, isoflavone ... prevention and treatment of obesity Nutrient composition of soy protein Soybeans provide one of the most abundant plant sources of dietary protein The protein content of soybeans varies from 36% ... with values of < 0.3 mg isoflavones/g soy protein Effect of dietary soy protein in animals and humans with obesity A number of studies in animals and humans suggest that consumption of soy protein...
  • 11
  • 670
  • 2
Báo cáo y học: "Functional genomics analysis of low concentration of ethanol in human hepatocellular carcinoma (HepG2) cells. Role of genes involved in transcriptional and translational processes"

Báo cáo y học: "Functional genomics analysis of low concentration of ethanol in human hepatocellular carcinoma (HepG2) cells. Role of genes involved in transcriptional and translational processes"

Ngày tải lên : 31/10/2012, 15:28
... with a SLR of 3.30, 2.61, 1.68 and 1.52, respectively ANK3 was the only significantly down-regulated gene with a SLR of -5.02 Figure Hierarchical clustering analysis of gene expression profile in ... concentrations of ethanol (100 mM) induced the expression of genes involved in the metabolism of ethanol [16] In addition, the metabolism of ethanol 33 results in an increased production of toxic metabolites ... common expression profiles of genes in various categories demonstrated by cDNA microarray analysis Hepatology 2001;33:676-91 Okabe H, Satoh S, Kato T, et al Genome-wide analysis of gene expression...
  • 8
  • 702
  • 0
Báo cáo y học: " Low concentration of ethanol induce apoptosis in HepG2 cells: role of various signal transduction pathways"

Báo cáo y học: " Low concentration of ethanol induce apoptosis in HepG2 cells: role of various signal transduction pathways"

Ngày tải lên : 31/10/2012, 15:37
... numbers of cells with apoptosis-associated alterations of the nuclei and without membrane barrier dysfunction were determined within a field of view at a magnification of X400 A total of 10 randomly ... inhibition of the GPCR signaling pathway as shown by phosphorylation of GRK2 and PKCα; with values of 109% and 104%, respectively, combined with dephosphorylation of ROKα, PKCδ and PKCμ; with values of ... 8.02 (Systat Software, Erkrath, Germany) was used for statistical analysis 162 Results Short exposure to mM ethanol induces phosphorylation of protein kinases Table shows the effect of mM ethanol...
  • 8
  • 510
  • 0
Báo cáo y học: "Human toxoplasmosis and the role of veterinary clinicians"

Báo cáo y học: "Human toxoplasmosis and the role of veterinary clinicians"

Ngày tải lên : 03/11/2012, 11:06
... consequences of infection can be very severe, while the risk of living with one’s beloved cat is practically nill References Angulo FJ, Glaser CA, Juranek DD et al Caring for pets of immunocompromised ... Dis.1994;18:14-24 Han K, Shin DW, Lee TY, et al Seroprevalence of Toxoplasma gondii infection and risk factors associated with seropositivity of pregnant women in Korea J Parasitol 2008; 94: 963-965 ... 963-965 Grant S and Olsen CW Preventing zoonotic diseases in immunocompromised persons: the role of physicians and veterinarians Emerg Infect Dis 1999; 5: 159-163 http://www.medsci.org ...
  • 2
  • 499
  • 0
The role of language in adult education and poverty reduction in Botswan

The role of language in adult education and poverty reduction in Botswan

Ngày tải lên : 05/11/2012, 16:27
... majority of learners get little benefit from schooling, either in terms of acquiring the necessary language proficiency or in terms of content This is because local language which are usually of low ... the preserve of the few (elites) The choice of which language or dialect to use to teach (medium of instruction) reflects the interests of those elite In countries in which one of the languages ... Fishman 1968) on the use of vernacular languages states that a mother tongue is a person’s natural means of self expression and one of his needs is to develop his power of self expression to the...
  • 5
  • 837
  • 1
153 The role of marketing activities to bankcard and actual state of Ngân hàng nông nghiệp và phát triển nông thôn (AgriBank) cards

153 The role of marketing activities to bankcard and actual state of Ngân hàng nông nghiệp và phát triển nông thôn (AgriBank) cards

Ngày tải lên : 03/04/2013, 12:13
... billion, balance of call deposit account was VND 1,425 million Collected service fee of the last quarter of the year was zero because of free issuing card in this period However, accumulate of 12 months ... 1.- Quantity of ATM, EDC Source Report on result of 2009 card products and services The graph shows the quantity of ATM, EDC changing over period of four years In 2007, the quantity of EDC is lesser ... centre of the transaction process, maintaining the flow of funds and information between issuing and acquiring members The exchange of financial information is called clearing The exchange of the...
  • 33
  • 662
  • 0
The role of advertising in society

The role of advertising in society

Ngày tải lên : 16/04/2013, 11:05
... limitation of means of communication and citizens’ perception The most popular type of advertising is on TV Following is the advertising price chart of some typical types of advertising 65 Number of ... Part I : General knowledge of advertising Some typical concepts of advertising Classifications of advertising Part II : The role of advertising in society Economic effects of advertising a On governments ... has over 70 percent of the soft drink market, and the company's advertising objective is to encourage consumers to drink more Primary demand advertising is often used as part of a promotional strategy...
  • 27
  • 1.1K
  • 1
Evaluation of employees’ job satisfaction and role of gender difference   an empirical study at airline industry in iran

Evaluation of employees’ job satisfaction and role of gender difference an empirical study at airline industry in iran

Ngày tải lên : 11/09/2013, 11:44
... -3.67 as medium level of satisfaction and the means over 3.67 as high satisfaction Table shows the result of descriptive analysis for level of job satisfaction Examples of job satisfaction items ... consists of several facets, including satisfaction with the supervisor, relationship with coworkers, present pay, nature of work, and opportunities for promotion 4.1 Nature of work The nature of the ... personal traits and characteristics of the job (Wexley and Yukl, 1984) To get deep understanding of employees, characteristics of jobs and their relation to the issue of job satisfaction various theories...
  • 11
  • 591
  • 0
The role of leadership theory in raising the profile of women in management

The role of leadership theory in raising the profile of women in management

Ngày tải lên : 08/10/2013, 15:56
... because of the low profile of women in management at this time, and it can be assumed that the profile of women in management would not have been advanced in any significant way from this body of ... towards raising the profile of women in management, as the theory was constructed as a male model at a time when women were not visible in paid employment One of the off shoots of the great man theory ... 330) which is more typical of male behaviours Of interest is the inclusion of ‘‘control’’ as a significant feature of the transactional style, common in definition of leadership in the 1990s...
  • 16
  • 962
  • 1
Globalization: the Role of Institution Building in the Financial Sector _ The Case Study of China

Globalization: the Role of Institution Building in the Financial Sector _ The Case Study of China

Ngày tải lên : 18/10/2013, 07:15
... percent of the total by the end of 1999 14 Table Structure of Financial Assets Year Mo Deposits with FIs Loans of FIs Borrowin Bonds g by the Ministry of Finance Capitalizat Insurance Total ion of ... under the framework of financial globalization II Review of Institution Building in the Financial Sector A Main driving forces of institution building A review of the developments of China’s financial ... Sources of Enterprises C Monetarization of the economy sharply increased The monetarization of an economy is measured by the M2/GDP ratio, of which, M2 is broad money that equals to the sum of currency...
  • 26
  • 975
  • 1