emerging therapeutic options for breast cancer chemotherapy during pregnancy

... individual risks for breast cancer 60-85% and may be identified in 5-10% of all breast cancer cases. 28 Personal history of noninvasive breast cancer or previous abnormal breast biopsy containing ... participants for women age 40-49 years that reported relative risk (RR) reduction in breast cancer mortality. We conducted similar updates for other age groups for context. We used breast cancer ... risk for breast cancer mortality of 0.83 (95% confidence interval [CI], 0.66-1.04) for women randomly assigned to screening, and a number needed to invite for screening to prevent one breast cancer...

Ngày tải lên: 14/02/2014, 21:20

... background for our information in this leaflet below. SCREENING FOR BREAST CANCER WITH MAMMOGRAPHY What are the benefits and harms of attending a screening programme for breast cancer? ... treatment for breast cancer in Norway: comparative analysis of cancer registry data. BMJ 2011;343:d4692. 20. NHS cancer screening programmes. BASO Breast Audit 1999/2000. www.cancerscreening.nhs.uk/breastscreen/publications.html ... disease and cancer. It therefore no longer seems reasonable to attend for breast cancer screening. In fact, by avoiding going to screening, a woman will lower her risk of getting a breast cancer...

Ngày tải lên: 15/02/2014, 05:20

... nanocapsule form. This observation was consistent with a previous report [48] related to a nanoparticulate form of another anticancer drug (doxorubicin) tested on a different breast cancer cell ... characterized for particle size, zeta potential, EE%, drug release kinetics, morphology, crystallinity, and cytotoxicity on the SUM 225 breast cancer cell line by dynamic light scattering, high performance ... acceptance. Fully formatted PDF and full text (HTML) versions will be made available soon. Encapsulation of docetaxel in oily core polyester nanocapsule intended for breast cancer therapy Nanoscale...

Ngày tải lên: 18/06/2014, 22:20

... in human breast cancer cells and therefore have considerable potential for treatment of breast cancer. Keywords Nanoparticles Á MDR Á Pluronic F68 Á Poly (e-caprolactone) Á Docetaxel Á Breast cancer Introduction Cancer ... multidrug resistance in human breast cancer cells and therefore have considerable potential for treatment of breast cancer. Acknowledgments The authors are grateful for financial support from the ... 54.37% for Taxotere Ò to 49.16% (i.e. a 11.42% increase in cytotoxicity, p [ 0.05) for PCL NP formulation and 36.63% (i.e. a 38.88% increase in cyto- toxicity, p \0.05) for PCL/Pluronic F68 NP formulation. Similarly,...

Ngày tải lên: 22/06/2014, 00:20

... treatment is therefore not as effective as it should be. Mortality due to breast cancer is decreasing in most western countries, because of mass screening, frequent use of post-operative chemotherapy ... Eric Miska [2] use molecular methods to classify breast cancers more precisely. BBrreeaasstt ccaanncceerr hheetteerrooggeenneeiittyy Because breast cancer heterogeneity arises from many different ... enough for therapeutic selection but knowledge of both genotype and phenotype is required. Furthermore, Chin et al. [1] provide lists of copy number alterations and potential cancer genes in breast cancers...

Ngày tải lên: 06/08/2014, 18:21

... CS, Nelson BK: Seroma formation following breast cancer surgery. Breast J 2003, 5:385-8. 10. Woodworth PA, McBoyle MF, Helmer SD, Beamer RL: Seroma formation after breast cancer surgery: incidence ... of seromas following breast cancer surgeries: seromas following breast cancer surgeries. Breast J 2007, 13:588-92. 21. Burak WE Jr, Goodman PS, Young DC, Farrar WB: Seroma formation following ... Southwestern Medical Center undergoing ALND for confirmed breast cancer metastasis from January 1, 2005 to December 1, 2009 were eligible. Nearly 250 ALND’s were performed during this time period. In 2007,...

Ngày tải lên: 09/08/2014, 02:20

... localized estrogen receptors in human breast cancer. Cancer Res 1990, 5012:3545-3550. 9. British Breast Group: Assessment of response to treatment in advanced breast cancer. Lancet 1974, 2:38-39. 10. ... receptor positive, operable primary breast cancer in elderly (age > 70 years), locally advanced or metastatic breast cancer; (2) disease deemed suitable for treatment by hormonal manipulation; ... therapy. Methods Case-notes of the breast cancer patients treated in the Nottingham breast unit since 1998 fulfilling the follow- ing criteria were studied retrospectively: ã ER positive invasive breast carcinoma...

Ngày tải lên: 09/08/2014, 02:21

... tamoxifen for prevention of breast cancer. Br J Cancer 1989, 60(1):126-31. 4. Fisher B, Costantino JP, Redmond CK, Fisher ER, Wickerham DL, Cronin WM: Endometrial cancer in tamoxifen-treated breast cancer ... Agency for Research on Cancer, Lyon, France 1996, 66:253-365. 11. Swerdlow AJ, Jones ME: Tamoxifen treatment for breast cancer and risk of endometrial cancer: a case-control study. J Natl Cancer ... Early Breast Cancer Trialists’ Collaborative Group: Tamoxifen for early breast cancer: an overview of the randomized trials. Lancet 1998, 351:1451-1467. 9. Cuzick J, Powles T, Veronesi U, Forbes...

Ngày tải lên: 09/08/2014, 03:22

... imaging for most patients, or mammography size for patients with micro- calcification dominant lesions. Ultrasound-guided biop- sies were used for sonographically visible lesions, and were performed ... BioMed Central Page 1 of 5 (page number not for citation purposes) World Journal of Surgical Oncology Open Access Research Predictive factors for breast cancer in patients diagnosed atypical ductal ... at the time of biopsy is an independent predictive factor for breast cancer at surgical excision in patients with diagnosed ADH at CNB. For patients diagnosed with ADH at CNB, only complete surgical...

Ngày tải lên: 09/08/2014, 04:21

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Ngày tải lên: 11/08/2014, 16:20

... surgical management of early stage invasive breast cancer. Curr Probl Surg 2004, 41:877-936. 2. National Comprehensive Cancer Network (NCCN) Clinical Guidelines in Oncology for Breast Cancer (V.1.2009) [http:/ /www.nccn.org/professionals/physician_gls/PDF /breast. pdf] 3. ... analysis for SLNs in ILC versus IDC cases, that intraoperative frozen section analysis of SLNs during breast cancer surgery for ILC should remain an important standard of care. This allows for accurate ... positive predictive value (100% vs. 100%) for frozen section analysis for confirming the presence of metastatic disease within SLNs during breast cancer surgery for ILC and IDC. Conclusion: Since there...

Ngày tải lên: 09/08/2014, 04:21