ejaculation what causes them and how are they treated

... mutations are known, and only a handful are nonsense mutations or involve the replacement of a residue in the active site of GCase The vast majority of the disease-causing mutations occur randomly ... protein crystallography: liganded proteins tend to crystallize more readily than their unliganded counterparts because their structures are more stable Therefore, the obvious candidates for specific ... all of the pharmacological chaperones now under development are Ringe and Petsko: Journal of Biology 2009, 8:80 80.3 active-site ligands However, tight specific binding anywhere on the surface of...

Ngày tải lên: 06/08/2014, 19:21

... business today You may have read about service-oriented architectures and are wondering how they can affect your business as well as how they can be of use to you By looking at it from both a real-world ... development and delivery for WestLake Training and Development He has been designing and developing leading software solutions for over 15 years and has also developed client training focused on use and ... Service-Oriented Architecture :What Is It and How Can It Help Your Business? Charlie Fink, VP of Product Development and Delivery, Westlake Introduction Service-oriented...

Ngày tải lên: 16/10/2013, 12:15

... find a harmony between what they expect and what they are able to realize from life But suppose the pains of separation are amplified by a combination of parental demands and individual needs to ... proliferated and stimulated consumers’ desires The example of Polaroid and Land suggests how leaders think about goals They are active instead of reactive, shaping ideas instead of responding to them ... managers and leaders make in their careers Managers see themselves as conservators and regulators of an existing order of affairs with which they personally identify and from which they gain...

Ngày tải lên: 24/10/2013, 07:15

... also a discoverable purpose, and a show of relevancy, and remain in the neighborhood of the subject in hand, and be interesting to the reader, and help out the tale, and stop when the people cannot ... finish the work we are in, to bind up the nation's wounds; to care for him who shall have borne the battle, and for his widow and orphan—to all which may achieve and cherish a just and lasting peace ... letters and prospectuses And who among us doesn't write resumes, cover letters, memos, faxes, and business letters? We all need to develop good writing style Chapter : What Is Style, and How Do...

Ngày tải lên: 01/11/2013, 16:20

... you and your family and limit the effects of pandemic flu Use these three steps to prepare: Make a plan for you and your family at home Plan for how a pandemic might affect your work Prepare ... contact with those who are ill • Avoid shaking hands if you are ill and with others who are ill • Stay away from others when you are sick Stay home from work, school or running errands if you can • ... treat and prevent seasonal flu will help To help prevent spreading the flu, be sure to: • Wash your hands often with soap and water Use alcohol-based hand sanitizer when soap and water are not...

Ngày tải lên: 20/12/2013, 23:15

... business today You may have read about service-oriented architectures and are wondering how they can affect your business as well as how they can be of use to you By looking at it from both a real-world ... development and delivery for WestLake Training and Development He has been designing and developing leading software solutions for over 15 years and has also developed client training focused on use and ... Service-Oriented Architecture :What Is It and How Can It Help Your Business? Charlie Fink, VP of Product Development and Delivery, Westlake Introduction Service-oriented...

Ngày tải lên: 21/12/2013, 06:18

... land) affected, the scientific basis and understanding of public risks, the source(s) of the Congressional Research Service Federal Pollution Control Laws: How Are They Enforced? pollutants, and ... Laws: How Are They Enforced? The regulated community, public interest groups, federal and state officials, and Congress are often divided on whether to pursue legislation that would further expand ... results, including actions initiated and concluded, and penalties and other sanctions assessed The reliability and consistency of EPA and state databases, and how effectively the reported information...

Ngày tải lên: 29/03/2014, 14:20

... paralegals—will know how to prepare and file the forms correctly Unfortunately, standardized forms are still the rare exception to the rule Few courts offer them, and in most places they are available ... PLACE TO HANDLE ROUTINE PAPERWORK Courts are designed primarily to handle adversarial proceedings, where lawyers argue for each side and a great deal of time and money are spent concocting and debating ... lemon laws are seriously flawed Even though arbitration hearings are often free and designed to take place without a lawyer, car manufacturers are at a distinct advantage— obviously, they are more...

Ngày tải lên: 18/04/2014, 14:05

... results, co-ordinated and prepared the initial manuscript KSR and JA administered the survey GAM and EBJ reviewed the literature and edited the manuscript All authors read and approved the final ... and needs of doctors who have already migrated to the UK are likely to disrupt the career paths of many non-European doctors, many of whom have spent a considerable duration of time working and ... applicants are available This may result non European doctors being unable to compete for NHS jobs The number of doctors affected by this is estimated to be between ten thousand [4] and sixteen thousand...

Ngày tải lên: 18/06/2014, 17:20

... model; triage and admission decisions are variable depending on the attending staff, and nonmedical reasons are rarely discussed openly Moreover, criteria for admission are not made public and any ... critical care services, what guidance admission and discharge policies then truly provide? The literature to date sheds little light on how admission, discharge and triage criteria are used [4] ... created, such policies are rarely looked at, front-line staff are unaware of their content [4,5] and (some would argue) they are rarely followed by the ICU team [6-10] Currently, little information...

Ngày tải lên: 13/08/2014, 03:20

... and make sure that they are in positions where they can grow and develop, and then help them so In his follow-up book, The One Thing You Need to Know About Great Managing, Great Leading, and ... the firm’s own people as they were, even though they had known them for years and they were dealing with them every day Some people are much better than others at assessing candidates While there ... elusive Chapters 4, 5, and address the whens, whats, and wheres: when to look, what to look for, and where you’re likely to find what you’re looking for Throughout these chapters (and elsewhere in the...

Ngày tải lên: 28/06/2014, 21:20

... and make sure that they are in positions where they can grow and develop, and then help them so In his follow-up book, The One Thing You Need to Know About Great Managing, Great Leading, and ... the firm’s own people as they were, even though they had known them for years and they were dealing with them every day Some people are much better than others at assessing candidates While there ... elusive Chapters 4, 5, and address the whens, whats, and wheres: when to look, what to look for, and where you’re likely to find what you’re looking for Throughout these chapters (and elsewhere in the...

Ngày tải lên: 10/08/2014, 07:21

... hire them and train them, and based on this model—we have created an organization that succeeds solely due to its ability to assess people So these are learnable skills I learned them, and you ... DECISIONS And great people decisions need active management They are less like a physical infrastructure, and more like money: They achieve their true potential only if you figure out how to deploy them ... I While great people decisions are essential for personal and organizational success, there are compelling reasons why mastering them is extremely hard and they are the subject of our next chapter...

Ngày tải lên: 10/08/2014, 07:21

... Page 123 What to Look For 123 What about “Personality”? IQ and experience are “hard” factors, in the sense that they can be more easily verified, and it is somewhat easier to agree on terms and interpretations ... subjects in later chapters But acts of God are the rare exception In business, as in most of life, acts of people are what we have to worry about So, what are the ccc_people_085-116_ch04.qxd 4/3/07 ... 115 Jim Collins was asked how “good to great” companies decide who should get off the bus, and how they implement those difficult decisions, this was his answer: They are rigorous, not ruthless...

Ngày tải lên: 10/08/2014, 07:21

... 1:11 PM Page 125 What to Look For 125 ment from Harvard, and then embarked upon an outstanding journalistic career, which included two nominations for the Pulitzer Prize and a Career Achievement ... competency is what we call “collaboration and influencing.” Those demonstrating this competency are effective in working with peers, partners, and others who are not in the direct line of their command ... selfcontrol, transparency, adaptability, achievement orientation, initiative, and optimism); (3) social awareness (empathy, organizational awareness, and service orientation); and (4) relationship...

Ngày tải lên: 10/08/2014, 07:21

... some outstanding successes and some formidable failures So you should be particularly careful, when things are going well, to look at the future, and make sure that the person you are promoting ... positions, for which specialized know -how and expertise are key Those “hard” competencies are typically easier to evaluate than “soft” managerial and leadership abilities and, as a result, this circumstance ... an alternative you are unaware of, and you can’t choose an alternative better than the best of those who are put before you In a perfect world, an organization would choose a candidate from a large...

Ngày tải lên: 10/08/2014, 07:21

... for professionals and managers include interviews, resumes, and references.1 While many other techniques are called upon, they are either inherently suspect (e.g., astrology and graphology), not ... your questions should be focused on behaviors, and should be followed up with significant probing to understand what was the candidate’s exact role, and what were the consequences of his or her actions ... all over the world, and our CEO, Dan Meiland By that time, we had conducted significant external and internal research, and were analyzing in detail what made for the outstanding performance of...

Ngày tải lên: 10/08/2014, 07:21

... “Give them lots of money, and a picture Paint a picture for ccc_people_229-254_ch08.qxd 4/3/07 1:14 PM Page 235 How to Attract and Motivate the Best People 235 them If they are successful, they are ... money and other types of compensation are far more important So you have to understand the candidate’s interests and motivations, while making your best effort to try to genuinely understand his ... convinces like conviction If you have done your homework, understand the candidate’s motivation, and are convinced that what you are offering is the best for her, (almost) nothing will stop you...

Ngày tải lên: 10/08/2014, 07:21

... it: How many of the presidents or prime ministers in office today, even in the most developed countries, are the best possible people to hold those posts? How many of them are outstanding, and how ... discipline and objectivity in assessing candidates—even when father assessed son Both showed courage and compassion In my estimation, that’s how they beat the odds cited in the McKinsey study And the ... we are prepared to smile the instant the other person smiles An emerging notion in the philosophy of mind, moreover, argues that we understand others not by observing them and thinking about them, ...

Ngày tải lên: 10/08/2014, 07:21

... Objectives • Describe wireless wide area networks (WWANs) and how they are used • Describe the applications that can be used on a digital cellular telephone • Explain how cellular telephony functions ... devices that are simply reflectors 26 Satellite Broadband Wireless (continued) 27 Satellite Transmissions • Satellites generally send and receive on one of four frequency bands • Frequency band affects ... (MTSO) – Link between the cellular network and the wired telephone world – Controls all transmitters and base stations How Cellular Telephony Works (continued) How Cellular Telephony Works (continued)...

Ngày tải lên: 13/09/2012, 10:52