effects of substratum topography on cell behavior

... cells, Cell viability, Cell migration, Cell cycle Background Breast cancer is one of the most common types of cancer and the second leading cause of cancer death in women Surgical resection of ... 18:666 Page of 12 Fig Effect of local anesthetics of plasma and 10x plasma concentrations on migration of breast cancer cells Wound healing assay showing inhibition of cell migration after 24 ... Conclusion The effects of local anesthetics on viability and migration of breast cancer cells depends on the concentration of individual anesthetic, the duration of exposure and the cell line Levobupivacaine

Ngày tải lên: 24/07/2020, 01:38

... 300 200 100 0 Control * Control PDGF EGF TGFβ Control PGE2 400 p-ERK , % of control * p-ERK , % of control p-AKT, % of control p-ERK, % of control 1500 lin ko rs Fo * 300 200 100 Control Fluprostenol ... synthesis in the rat stellate cells, albeit at high concentrations of the inhibitor, which may lead to nonspecific effects Thus, at high concentrations of NS-398, inhibition of DNA synthesis has been ... regulators of pancreatic stellate cell activation [6] Activation promotes PSC proliferation, migration, and extracellular matrix (ECM) deposition Overexpression of COX-2 has been reported in a number of

Ngày tải lên: 14/10/2020, 17:09

... Likelihood of Provider Accompanying Consumer to Locations and Saying Consumer Needs Help Getting to Locations by Each Additional Hour of Provider’s Daily Time in Travel of Specific Locations……………………………………………………………………… ... from the one submitted as a master’s thesis. ii Abstract The Effects of Land Use on the Mobility of Elderly and Disabled and Their Homecare Workers, and the Effects of Care on Client ... Housing and Population Density by Likelihood of Consumers Being Unable to Reach Destinations in Previous Month Because of Transportation Problems……………………………………………………… 84 11 Zone by Difficulties

Ngày tải lên: 14/03/2014, 17:20

... capabilities; 2) facilitate communication and sharing of best practice information among and within organizations of all types based on a common understanding of key performance requirements; and, ... Customer Satisfaction and Relationship 40 Enhancement 4.0 Information Analysis 80 4.1 Selection and Use of Information and Data 25 4.2 Selection and Use of Comparative Information 15 and Data 4.3 ... relationship between the financial performance of a health care organization and its patient loyalty A secondary consideration was analysis of the demographic and psychographic characteristics of

Ngày tải lên: 16/03/2014, 03:20

... age. Section 4 is devoted to the calibration of the model on Spanish car market data. Section 5 quantifies the main eects of the Prever scheme both on car sales and on the average age of the stock, ... The microeconomic replacement problem Time is continuous. There is a continuum of heterogeneous consumers with preferences h w f (w)+v (w  d (w)) defined on nondurable consump- tion f and durable ... dierent in their marginal utility of nondurables consumption. 3 Note that we are also assuming that marginal utility of nondurables consumption and quality of new cars are growing at the same

Ngày tải lên: 16/03/2014, 12:20

... glucose concentrations (5–20 mm). The concentration control coefficient of glucokinase on Glc6P (1.4–1.7) was relatively inde- pendent of glucose concentration, whereas the flux control coefficients of Glc6P ... control coefficient (> 1) on Glc6P, which is relatively independent of glucose concentration (1.4–1.7); second, the rate of glycogen synthesis is a sigmoidal function of Glc6P concentration ... depletion of phos-a relieves the inhibition of G L , and (c) Glc6P stimulates the conversion of GSB to GSA by a substrate- directed mechanism. L. Ha ¨ rndahl et al. Control strength of Glc6P on glycogenesis FEBS

Ngày tải lên: 16/03/2014, 14:20

... management of air quality and the implementation of public-health actions on local, national and European levels. In specific, APHEIS aims to provide decision makers, environmental-health professionals ... short-term effects of air pollution on health in Europe. .. representative of all the admissions of the population studied? Hospital admissions data should be representative of ... replaced by the weighted average of the values of the rest of the monitoring stations,... aetiology of the effects of pollution on health 21 APHEIS - Scientific

Ngày tải lên: 23/03/2014, 00:20

... Reduce Ozone Exposure 6 Carbon Monoxide 6 Who is Most Sensitive to the Health Effects of Carbon Monoxide? 6 Air Quality Standards for Carbon Monoxide 7 Sources of Carbon Monoxide 7 Health Effects ... Effects of Carbon Monoxide 7 Prenatal Effects of Carbon Monoxide 8 Airborne Particles 8 The Challenge of Measuring Particle Pollution 8 Sources of Particle Pollution 9 Historic Air Pollution ... significant source of carbon monoxide. Tobacco smoke can contain very high concentrations of carbon monoxide (1,000 ppm to 50,000 ppm). Carbon monoxide levels in the homes of children whose

Ngày tải lên: 23/03/2014, 02:20

... relation of production People in a class share similar working conditions and economic fate These working and economic conditions constitute the objective face of the class formation Second, the ... effect of personal characteristics on job performance The primary contribution of this study is its inclusion of personality variables in the earnings function in order to determine economic ... exact contribution of education remains ambiguous In addition to considering other determinants, such as gender, experience, union membership, etc., the rate of return studies often concentrate on

Ngày tải lên: 23/03/2014, 05:22

... the effects of 20E both on cell proliferation and morphological changes of IAL-PID2 cells. Isolation and characterization of P. interpunctella EcR-B1 mRNA Cloning of a PIEcR cDNA frament. We wondered whether ... t o the inhibition of cell proliferation and long-term morphological changes of I AL-PID2 cells [23,24,41]. To examine the effects of J H II on this genetic cascade, IAL-PID2 cells were cultured ... 20E-induced differentiation of imaginal wing cells. We first tested the sensitivity of IAL-PID2 cells to JH II examining the effects of this hormone on 20E-induced late responses such as pro lifera- tive

Ngày tải lên: 23/03/2014, 13:20

... behavioural effects 162 Conclusions 182 Annex 1: List of contributors 184 ABSTRACT Concerns about the adverse effects of air pollution on children’s health and development are important determinants of ... this publication not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, ... research into the effects of air pollution common in contemporary European cities on infant health, the development of lung function, childhood infections, the development and severity of allergic

Ngày tải lên: 28/03/2014, 09:20

... region, demonstrated a Ca2+-induced bongkrekate-sensitive permeability transition pore, allowing the suggestion that this region of ANT may contain the binding site for bongkrekate Introduction ... mammalian consensus, addition of ADP in the absence of oligomycin to the suspension caused Artemia mitochondria to show ‘shrinkage’ upon addition of CaCl2 (Fig 2B), which is known to occur because of ... indicated (C) Reconstructed time courses of extramitochondrial [ATP] appearing in the medium upon addition of ADP (where indicated) in rat liver mitochondria, and effect of mitochondrial inhibitors

Ngày tải lên: 29/03/2014, 00:20

... doctoral dissertation of Ayse E Sile entitled The Effects of Macroeconomic Uncertainty on Irreversible Investment submitted to the faculty of Economics in partial fulfillment of the requirements ... uncertainty on a panel of Ghanaian manufacturing firms She uses a survey of Ghanaian manufacturing firms, which includes a question on firms’ perceptions of uncertainty in the context of a volatile ... uncertainty on the investment trigger By doing so, I show that the sign of the uncertainty-investment relationship not only depends on the magnitude of price elasticity of demand but also on the type of

Ngày tải lên: 30/03/2014, 01:20

... citation purposes) Journal of Translational Medicine 2009, 7:34 Figure with TNF-α Suppressive effects of ginsenosides on U937 cells stimulated Suppressive effects of ginsenosides on U937 cells ... part of the programme endorsed by the Consortium for the Globalization of Chinese Medicine The authors are most grateful to Prof YC Cheng of Yale University and Prof Paul Tam of University of Hong ... Hong Kong for their valuable advice and insightful comments We also thank Genome Research Centre of The University of Hong Kong for the technology support Conclusion In conclusion, the results of...

Ngày tải lên: 18/06/2014, 15:20

... up-regulation of ICAM-1 and VCAM-1 expression by murine kidney tubular epithelial cells: hyaluronan triggers cell adhesion molecule expression through a mechanism involving activation of nuclear ... synovial cells in this study were raised in either an environment devoid of HA (control groups and 2) or in a stable environment containing HA (groups and 4) This permitted a controlled evaluation of ... linkage and – Pearson correlation as the measure of dissimilarity Shading is indicative of relative expression: white, median expression; deepening shades of red, increasing expression of the probe...

Ngày tải lên: 09/08/2014, 08:23

... CHARACTERIZATION OF BIOPOLYMER AND THE EFFECTS OF MECHANICAL PROPERTIES OF EXTRACELLULAR MATRIX ON CELL BEHAVIORS WONG LONG HUI (B.Eng.(Hons.), NTU) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY ... cells and the physical microenvironment, through cell- cell and cell- ECM interactions, determines the progression of the invasion process, as shown in Figure 1.4 [39] The interactions of the cells ... Stress Contribution by the Series Elastic Component 𝜀 𝑆𝐸𝐶 Strain Contribution by the Series Elastic Component 𝜎 𝑆𝑉𝐶 Stress Contribution by the Series Viscous Component 𝜀 𝑆𝑉𝐶 Strain Contribution by...

Ngày tải lên: 09/09/2015, 11:28

... The Effects of Childhood Stress on Health Across the Lifespan is a publication of the National Center for Injury Prevention and Control of the Centers for Disease Control and Prevention Centers ... longer, and were conducted by professionals (as opposed to trained paraprofessionals).23 The Effects of Childhood Stress on Health Across the Lifespan Community, Organizational, and Social Level ... dramatic rise in hormone levels Types of Stress Following are descriptions of the three types of stress that The National Scientific Council on the Developing Child has identified based on available...

Ngày tải lên: 12/02/2014, 19:20

... sponsored by the United States Army iii iv The Effects of Equipment Age on Spare Part Costs: A Study of M1 Tanks For more information on RAND Arroyo Center, contact the Director of Operations ... Tanks, Santa Monica, CA: RAND Corporation, MR-1789-A, 2004, p 27 (age-failure relationship) and p 48 (high-cost parts) Congressional Budget Office, The Effects of Aging on the Costs of Operating ... weapon systems 8 The Effects of Equipment Age on Spare Part Costs: A Study of M1 Tanks budget constraints all probably contribute to a dampening effect on the agecost relationship Various Unit Behaviors...

Ngày tải lên: 17/02/2014, 22:20

... Comparison of Battalion Failure Distributions and Poisson Distribution in 2nd Infantry Division B.6 Comparison of Battalion Failure Distributions and Poisson Distribution in 3rd Infantry Division ... (Location 1, 180 days) B.1 Illustration of Failure Data Overdispersion B.2 Comparison of Battalion Failure Distributions and Poisson Distribution in 1st Cavalry Division B.3 Comparison of Battalion ... Battalion Failure Distributions and Poisson Distribution in 4th Infantry Division B.4 Comparison of Battalion Failure Distributions and Poisson Distribution in 1st Infantry and 1st Armor Divisions:...

Ngày tải lên: 18/02/2014, 17:20