early warning systems for the identification of organizational risks

... However, the points raised are likely to be valid for other types of tumors For all these, the addition of appropriate cancer-free control materials to the screening panels might help in the identification ... regions adjacent to the actual tumor as the sole control is probably insufficient for the identification and selection of methylation markers for early cancer detection, although these control samples ... example of such an early alteration is hypermethylation of the gene SFN in breast cancer While this gene is hypermethylated in breast tumors and adjacent normal tissues, the breast epithelium...

Ngày tải lên: 14/08/2014, 21:20

... one of the N-best POS tagging result of the sentence is: T = NN VBD RB CD NNS NN NN For this POS sequence, the 2nd pass will try to determine the baseNPs as shown in Figure The details of the ... all the baseNP rules “+1” and “+4” denote the number of beat POS sequences retained in the first step And “UID+R” means the POS tagging result of the given sentence is totally correct for the ... benefit from baseNP information Whether or not the baseNP information can improve the precision of POS tagging in our approach is determined by the identifier assignment of the baseNP rules when...

Ngày tải lên: 08/03/2014, 05:20

... required for recovery of a given volume of gas than for recovery of the same volume of gas from conventional reservoirs Of the order of 50 shale gas wells might be needed to recover the same volume of ... fracturing of some tight gas and conventional reservoirs in the southern part of the North Sea and in Ref: AEA/ED57281/Issue Number 17 Support to the identification of potential risks for the environment ... the target formation might be close to the surface, the likelihood of any near surface formation retaining sufficient gas to be exploitable is much lower This is because of the need for the formation...

Ngày tải lên: 23/03/2014, 00:20

... rater versus the mean value of the other raters and the mean of the raters versus the speech recognition system The correlation is negative for the latter because the scales for the evaluations ... in the control group (P < 001) Inter-rater correlations were computed for each of the raters using the respective other raters as reference, that is, the mean of the four other raters for the ... treatment for oral cancer As a precondition for the evaluation of the patient groups, the extent of disorder is widespread, as seen by the results of the perceptual assessment and the ASR results The...

Ngày tải lên: 21/06/2014, 20:20

... supported by the Centre for Medical Systems Biology (CMSB) in the framework of the Netherlands Genomics Initiative (NGI) Furthermore, this project was sponsored by the VIDI grant of the Netherlands ... choosing cut-off values for the predicted risks The cutoff corresponding to a frequency of the high-risk group equal to the disease frequency optimizes both the sensitivity and the PPV, but is ... instead of 10-year risks, the frequency of the high-risk group for which the sensitivity and PPV are equal will be larger, because lifetime risks by definition are higher than 10-year risks Then for...

Ngày tải lên: 11/08/2014, 12:21

... characteristics of the substance and the potential risks, the better able they are to make informed choices about their drug use Involving people with addiction in the reporting and disseminating of overdose ... development of Canadian drug information systems Griffith and colleagues [31] provide a comprehensive overview of the difficulties associated with current drug information systems and early detection of ... only use information to seek out the offending substance and cause themselves further harm, the scant evidence available suggests that only a minority of users will look for drugs they perceive...

Ngày tải lên: 11/08/2014, 18:20

... be the most abundant and immunogenic of all VZV gps eliciting both, the formation of neutralizing antibodies and the mediation of cellular cytotoxicity [10,11] The relative importance of the ... with the cutoff band provided on the strip Additional material Additional file 1: Systematic pipeline for the identification of novel serological markers of VZV infection A) Nested PCR for the ... assay format and validated with a number of pre-characterized serum samples These validation data confirmed the seroreactivity of the identified marker antigens and revealed the suitability of the...

Ngày tải lên: 12/08/2014, 04:20

... accessions of wild relatives (1 accession of C myriocarpus, of C metuliferus, of C africanus, of C zeyheri, of C dipsaceus, of C prophetarum, of C meeusei, of C anguria, of C ficifolius and of Cucumis ... EcoTILLING allows the approximate location of the polymorphism within the locus studied and, therefore, restricts the necessity of sequencing the complete locus but only regions around the polymorphism ... with the DNA of the reference genotype (cultivar Védrantais) A black arrow on the top left of each image indicates the position of homoduplex DNA Arrows on the right of each panel indicate the...

Ngày tải lên: 12/08/2014, 05:20

... the marker-QTL genotype frequencies are identical for the two groups, the effects of the QTL may be different because of the impact of environPage of (page number not for citation purposes) Theoretical ... (4) The null hypothesis states that there is no QTL affecting the clonal expansion of the cells (the reduced model), whereas the alternative states that such a QTL does exist (the full model) The ... http://www.tbiomed.com/content/5/1/7 The LR is asymptotically χ 2-distributed with one degree of freedom A similar test for the existence of a QTL can be performed on the basis of the hypotheses about genotypic-specific...

Ngày tải lên: 13/08/2014, 16:21

... Thorgeirsson et al., 2006) There are two chief factors contributing to the high mortality of HCC One is the late presentation of HCC, where the dearth of symptoms at the early stage of the disease results ... 2003) that highlight the presence of cancer in the body They can be compounds secreted by the tumour itself or a result of a specific response of the body to the presence of cancer Generally, ... subjected to the types of proteolysis observed for other polypeptides The persistence and stability of the autoantibodies give them an advantage over other biomarkers, including the TAAs, which...

Ngày tải lên: 26/09/2015, 09:47

... Illustrated key for the identification of the Pleocyemata (Crustacea: Decapoda) zoeal stages, from the coastal region of south-western Europe Journal of the Marine Biological Association of the United ... also for Paradorippe granulata Different zoeal stages of brachyuran crabs (age distinctions) are easily determined using the number of natatory setae on the exopods of maxillipeds, the number of ... and zoea II of these species are nearly identical The larvae are distinguishable only from zoea III Zoea III –V of Hemigrapsus species differ in the number of dorsomedial setae on the abdominal...

Ngày tải lên: 25/08/2016, 22:35

... assessment of the trajectory of interconversion rates as a function of time of cold exposure, (b) comparison of the magnitudes of the various interconversion rates, and (c) lineup of the accessions ... photosynthesis, gas exchange of plants was measured by infrared gas analysis Measurements were performed during the first h 508 of the light phase, representing the time period of photosynthetic ... terms of the absolute values but also in the progression of the acclimation process This is an important outcome, as it allows estimation of the impact of different metabolic responses on the improvement...

Ngày tải lên: 14/02/2014, 22:20

... framework Even if the test is very limited by the number of topics, it confirms the potential of the framework, with the highest KING metric combination doubling the performance of the best ROUGE ... contrastive summary, the number of fragments of the reference summary which are also in the contrastive summary, in relation to the size of the contrastive summary DocSim: The number of documents used ... to this formula, the quality of a metric set X is the probability that the quality of a model is higher than the quality of a peer according to this metric set This formula satisfies all formal...

Ngày tải lên: 17/03/2014, 05:20

... interface has to be designed The research area therefore consists of two major parts, namely the design of the underlying system, and the design of the user interface. For future reference, the underlying system will be called 'system concept', the user interface will be  ... This concludes the user analysis. It's been investigated who the future users of the system will be, and what their needs  and requirements regarding ADAS are. The list of requirements can assist with the further definition of the system The following paragraph discusses the possibilities of the system concept, investigating which requirements can be  ... In practice, the driver won't directly interact with these functions. However, the results of these functions are very  important for the driver. The results of the functions are for example the ability to track a preceding vehicle, or to ...

Ngày tải lên: 23/03/2014, 10:20

... Latham Loop, the addition of a slack-forming loop to the film path to restrain the inertia of the take-up reel, and prevent the tearing of sprocket holes It also allowed for the use of films longer ... refined version of the Zoetrope with mirrors at the center of the drum instead of slots; public demonstrations of the Praxinoscope were made by the early 1890s with screenings of 15 minute 'movies' ... both the camera (kinetograph) and the method of viewing films (kinetoscope) were on the decline with the advent of more modern screen projectors for larger audiences.] The Lumiere Brothers: The...

Ngày tải lên: 23/03/2014, 11:20