... However, the points raised are likely to be valid for other types of tumors For all these, the addition of appropriate cancer-free control materials to the screening panels might help in theidentification ... regions adjacent to the actual tumor as the sole control is probably insufficient fortheidentification and selection of methylation markers forearly cancer detection, although these control samples ... example of such an early alteration is hypermethylation ofthe gene SFN in breast cancer While this gene is hypermethylated in breast tumors and adjacent normal tissues, the breast epithelium...
... one ofthe N-best POS tagging result ofthe sentence is: T = NN VBD RB CD NNS NN NN For this POS sequence, the 2nd pass will try to determine the baseNPs as shown in Figure The details ofthe ... all the baseNP rules “+1” and “+4” denote the number of beat POS sequences retained in the first step And “UID+R” means the POS tagging result ofthe given sentence is totally correct forthe ... benefit from baseNP information Whether or not the baseNP information can improve the precision of POS tagging in our approach is determined by the identifier assignment ofthe baseNP rules when...
... required for recovery of a given volume of gas than for recovery ofthe same volume of gas from conventional reservoirs Ofthe order of 50 shale gas wells might be needed to recover the same volume of ... fracturing of some tight gas and conventional reservoirs in the southern part ofthe North Sea and in Ref: AEA/ED57281/Issue Number 17 Support to theidentificationof potential risksforthe environment ... the target formation might be close to the surface, the likelihood of any near surface formation retaining sufficient gas to be exploitable is much lower This is because ofthe need forthe formation...
... rater versus the mean value ofthe other raters and the mean ofthe raters versus the speech recognition system The correlation is negative forthe latter because the scales forthe evaluations ... in the control group (P < 001) Inter-rater correlations were computed for each ofthe raters using the respective other raters as reference, that is, the mean ofthe four other raters forthe ... treatment for oral cancer As a precondition forthe evaluation ofthe patient groups, the extent of disorder is widespread, as seen by the results ofthe perceptual assessment and the ASR results The...
... supported by the Centre for Medical Systems Biology (CMSB) in the framework ofthe Netherlands Genomics Initiative (NGI) Furthermore, this project was sponsored by the VIDI grant ofthe Netherlands ... choosing cut-off values forthe predicted risksThe cutoff corresponding to a frequency ofthe high-risk group equal to the disease frequency optimizes both the sensitivity and the PPV, but is ... instead of 10-year risks, the frequency ofthe high-risk group for which the sensitivity and PPV are equal will be larger, because lifetime risks by definition are higher than 10-year risks Then for...
... characteristics ofthe substance and the potential risks, the better able they are to make informed choices about their drug use Involving people with addiction in the reporting and disseminating of overdose ... development of Canadian drug information systems Griffith and colleagues [31] provide a comprehensive overview ofthe difficulties associated with current drug information systems and early detection of ... only use information to seek out the offending substance and cause themselves further harm, the scant evidence available suggests that only a minority of users will look for drugs they perceive...
... be the most abundant and immunogenic of all VZV gps eliciting both, the formation of neutralizing antibodies and the mediation of cellular cytotoxicity [10,11] The relative importance ofthe ... with the cutoff band provided on the strip Additional material Additional file 1: Systematic pipeline fortheidentificationof novel serological markers of VZV infection A) Nested PCR forthe ... assay format and validated with a number of pre-characterized serum samples These validation data confirmed the seroreactivity ofthe identified marker antigens and revealed the suitability of the...
... accessions of wild relatives (1 accession of C myriocarpus, of C metuliferus, of C africanus, of C zeyheri, of C dipsaceus, of C prophetarum, of C meeusei, of C anguria, of C ficifolius and of Cucumis ... EcoTILLING allows the approximate location ofthe polymorphism within the locus studied and, therefore, restricts the necessity of sequencing the complete locus but only regions around the polymorphism ... with the DNA ofthe reference genotype (cultivar Védrantais) A black arrow on the top left of each image indicates the position of homoduplex DNA Arrows on the right of each panel indicate the...
... the marker-QTL genotype frequencies are identical forthe two groups, the effects ofthe QTL may be different because ofthe impact of environPage of (page number not for citation purposes) Theoretical ... (4) The null hypothesis states that there is no QTL affecting the clonal expansion ofthe cells (the reduced model), whereas the alternative states that such a QTL does exist (the full model) The ... http://www.tbiomed.com/content/5/1/7 The LR is asymptotically χ 2-distributed with one degree of freedom A similar test forthe existence of a QTL can be performed on the basis ofthe hypotheses about genotypic-specific...
... Thorgeirsson et al., 2006) There are two chief factors contributing to the high mortality of HCC One is the late presentation of HCC, where the dearth of symptoms at theearly stage ofthe disease results ... 2003) that highlight the presence of cancer in the body They can be compounds secreted by the tumour itself or a result of a specific response ofthe body to the presence of cancer Generally, ... subjected to the types of proteolysis observed for other polypeptides The persistence and stability ofthe autoantibodies give them an advantage over other biomarkers, including the TAAs, which...
... Illustrated key forthe identification ofthe Pleocyemata (Crustacea: Decapoda) zoeal stages, from the coastal region of south-western Europe Journal ofthe Marine Biological Association ofthe United ... also for Paradorippe granulata Different zoeal stages of brachyuran crabs (age distinctions) are easily determined using the number of natatory setae on the exopods of maxillipeds, the number of ... and zoea II of these species are nearly identical The larvae are distinguishable only from zoea III Zoea III –V of Hemigrapsus species differ in the number of dorsomedial setae on the abdominal...
... assessment ofthe trajectory of interconversion rates as a function of time of cold exposure, (b) comparison ofthe magnitudes ofthe various interconversion rates, and (c) lineup ofthe accessions ... photosynthesis, gas exchange of plants was measured by infrared gas analysis Measurements were performed during the first h 508 ofthe light phase, representing the time period of photosynthetic ... terms ofthe absolute values but also in the progression ofthe acclimation process This is an important outcome, as it allows estimation ofthe impact of different metabolic responses on the improvement...
... framework Even if the test is very limited by the number of topics, it confirms the potential ofthe framework, with the highest KING metric combination doubling the performance ofthe best ROUGE ... contrastive summary, the number of fragments ofthe reference summary which are also in the contrastive summary, in relation to the size ofthe contrastive summary DocSim: The number of documents used ... to this formula, the quality of a metric set X is the probability that the quality of a model is higher than the quality of a peer according to this metric set This formula satisfies all formal...
... interface has to be designed The research area therefore consists of two major parts, namely the design ofthe underlying system, and the design ofthe user interface. For future reference, the underlying system will be called 'system concept', the user interface will be ... This concludes the user analysis. It's been investigated who the future users ofthe system will be, and what their needs and requirements regarding ADAS are. The list of requirements can assist with the further definition ofthe system The following paragraph discusses the possibilities ofthe system concept, investigating which requirements can be ... In practice, the driver won't directly interact with these functions. However, the results of these functions are very important forthe driver. The results ofthe functions are for example the ability to track a preceding vehicle, or to ...
... Latham Loop, the addition of a slack-forming loop to the film path to restrain the inertia ofthe take-up reel, and prevent the tearing of sprocket holes It also allowed forthe use of films longer ... refined version ofthe Zoetrope with mirrors at the center ofthe drum instead of slots; public demonstrations ofthe Praxinoscope were made by theearly 1890s with screenings of 15 minute 'movies' ... both the camera (kinetograph) and the method of viewing films (kinetoscope) were on the decline with the advent of more modern screen projectors for larger audiences.] The Lumiere Brothers: The...