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... in compliance with the Finnish laws relating to the conduct of animal experimentation Autio et al EJNMMI Research 2011, 1:10 http: / /www. ejnmmires .com/ content/1/1/10 Male Sprague-Dawley rats ... lasting for 60 started at the time of injection The data acquired in list mode were iteratively reconstructed with a 3-D ordered subsets expectation maximisation algorithm with iterations, 16 subsets ... reaction kinetics The elimination rate constant (kel) was calculated as the negative slope of the linear part of the plot The plasma elimination half-life (t1/2) was calculated as t 1/2 = ln(2)/kel...
... 1:12 http: / /www. ejnmmires .com/ content/1/1/12 Page of Figure Schematic representation of different methods to determine the rate constants obtained from one-tissue compartment model (A) Rate constants ... is dominated by efflux transporters, while at later time points passive diffusion is more important The K1/k2 ratio of WT obtained with the 2-min scan data were statistically different compared ... described by some mathematical kinetic compartments [11] This model should be able to estimate the amount of radioactivity in each compartment, and the rate of exchange between these compartments In...
... femoral vein, for comparison to the femoral-femoral situation (the distance from the carotid catheter site to the probe was approximately 15 cm, comparable to the femoral situation) Statistics The ... function; SD, standard deviation Warnock et al EJNMMI Research 2011, 1:13 http: / /www. ejnmmires .com/ content/1/1/13 Page of 11 6000 6000 6000 cm catheter 15 cm catheter 45 cm catheter 5000 5000 5000 ... on Monte Carlo simulations and voxelized anatomical atlases to evaluate and correct uncertainties on radiotracer accumulation quantitation in beta microprobe studies in the rat brain Phys Med Biol...
... Dallas, TX, USA) The conjugation reaction was performed at Chan et al EJNMMI Research 2011, 1:15 http: / /www. ejnmmires .com/ content/1/1/15 Page of 11 4°C for 18 h DOTA-conjugated Fab were purified ... reconstructed using an orderedsubset expectation maximization (OSEM) algorithm (nine Chan et al EJNMMI Research 2011, 1:15 http: / /www. ejnmmires .com/ content/1/1/15 iterations) Prior to microSPECT imaging, ... (CB-DO2A) or sarcophagine (SarAr) chelators have been synthesized [30,31] A comparison of 64Cu complexed to Chan et al EJNMMI Research 2011, 1:15 http: / /www. ejnmmires .com/ content/1/1/15 a b Page of...
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