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... the area dorsal to the substantia nigra in the midbrain reticular formation By immunostaining using monoclonal antibody against the N-terminus of the human relaxin -3 A- chain [2], relaxin -3- immunoreactive ... [6 ,18 ] Although it can also bind and activate RXFP1 and RXFP4, relaxin -3 binds RXPF3 with higher affinity (0 . 31 nm) than RXFP1 (2.0 nm) or RXFP4 (1. 1 nm) [6 ,19 ] RXFP3 mRNA is abundant in the olfactory ... brain and facilitates water intake Peptides 31 , 11 24 1 13 0 Shiba K, Kageyama H, Takenoya F & Shioda S (2 010 ) Galanin-like peptide and the regulation of feeding behavior and energy metabolism FEBS...

Ngày tải lên: 29/03/2014, 21:20

... cell invasion using confocal laser scan microscopy Nat Med 19 97, 3( 10 ) :11 67- 71 Mamori S, Asakura T, Ohkawa K, Tajiri H: Survivin expression in early hepatocellular carcinoma and post-treatment ... CA, USA) was also used to synthesize cDNA for the individual TaqMan MicroRNA Assays (RNU48 Assay ID 0 010 06, RNU49 Assay ID 0 010 05, hsa-miRNA-44 9a Assay ID 0 01 030 , hsa-miRNA-449b Assay ID 0 016 08, ... hypoxia, at least in certain areas, which affects miRNA-449 and SERPINE1 expression Indeed, an inverse expression of miRNA-44 9a/ b and SERPINE1 mRNA expression could be demonstrated in almost all patient...

Ngày tải lên: 18/06/2014, 16:20

... microRNA-44 9a/ b impairs control over targeted SERPINE1 (PAI -1) mRNA - a mechanism involved in SERPINE1 (PAI -1) overexpression J Transl Med 2 010 , 8 :33 doi :10 .11 86 /14 79-5876-9-24 Cite this article as: ... et al.: Hypoxia-induced down-regulation of microRNA-44 9a/ b impairs control over targeted SERPINE1 (PAI -1) mRNA - a mechanism involved in SERPINE1 (PAI -1) overexpression Journal of Translational ... experiments are shown for cell line F -18 , but were likewise demonstrable in M15D expression by incorporating a dotted line The line was intended to highlight the additional increase of SERPINE1 (PAI -1) ...

Ngày tải lên: 18/06/2014, 19:20

... microRNA-44 9a/ b impairs control over targeted SERPINE1 (PAI -1) mRNA - a mechanism involved in SERPINE1 (PAI -1) overexpression J Transl Med 2 010 , 8 :33 doi :10 .11 86 /14 79-5876-9-24 Cite this article as: ... et al.: Hypoxia-induced down-regulation of microRNA-44 9a/ b impairs control over targeted SERPINE1 (PAI -1) mRNA - a mechanism involved in SERPINE1 (PAI -1) overexpression Journal of Translational ... experiments are shown for cell line F -18 , but were likewise demonstrable in M15D expression by incorporating a dotted line The line was intended to highlight the additional increase of SERPINE1 (PAI -1) ...

Ngày tải lên: 20/06/2014, 03:20

... Cambridge, 2004 [3] R C Bose and T Shimamoto Classification and analysis of partially balanced incomplete block designs with two associate classes J Amer Statist Assoc., 47 :15 1– 18 4, 19 52 [4] A ... A M Cohen, and A Neumaier Distance-regular graphs, volume 18 of Ergebnisse der Mathematik und ihrer Grenzgebiete (3) [Results in Mathematics and Related Areas (3) ] Springer-Verlag, Berlin, 19 89 ... On maximal partial spreads of H(2n +1, q 2) Discrete Math., 30 8 :37 5 37 9, 2008 [10 ] J A Thas Old and new results on spreads and ovoids of finite classical polar spaces “Combinatorics ’90”, Ann Discrete...

Ngày tải lên: 07/08/2014, 21:21

... drug-binding site(s) and TM12 In fact, mutations in TM12 were demonstrated to affect transport or ATPase activity [32 ,33 ], in particular, the stimulation of ATP hydrolysis by vinblastine and nicardipine ... Mutant Lext (%) t1 ⁄ (min) Lext (%) t1 ⁄ (min) Lext (%) t1 ⁄ (min) L976C A9 80C V982C G984C M986C V988C G989C S992C F994C 38 53 98 73 89 53 64 55 51 29 34 15 29 25 37 15 22 11 66 54 16 4 84 51 2 21 ... preparations ABCB1 isoform L976C A9 80C V982C G984C M986C V988C G989C S992C F994C Catalytic intermediate CM BM FM Basal AMP-PNP Vi trapped Basal AMP-PNP Vi trapped Basal AMP-PNP Vi trapped Basal AMP-PNP...

Ngày tải lên: 06/03/2014, 22:21

... Substrate numbering is the same as in Table Substrate kcat (s )1) 10 6 · Km (M) 10 )5 · kcat/Km (M )1 s )1) Ratio to reference PhAc-NH2 PhAc-6APAa NIPAB iso-NIPABb PhAc-MCA PhAc-NH 2a PhAc-pNAc NIPPA PhAc-pAB ... The data for the PA catalysed hydrolysis of PhAc-Asp and PhAc-Glu [ 13 ] and our data for PhAc-pAB, PhAc-mAB and PhAcoAB (Table 2) imply that the COOH group has to be positioned as in NIPAB for ... NIPPA PhAc-pAB PhAc-bNA PhAc-mAB PhAc-oAB 50 20 10 0 3. 2 50 20 7.8 3. 0 1. 9 2.5 2 .3 10 15 80 12 200 400 510 30 0 200 400 630 50 13 . 3 12 .5 2.7 2.5 0.5 0 .15 0 .1 0. 095 0.06 0.04 20 5 .3 5.2 1. 1 1. 0 0.2...

Ngày tải lên: 16/03/2014, 16:20

... (19 98) Polyamine-stimulated binding of diamine oxidase to DNA Acta Chem Scand 52, 9 21 929 36 D’Agostino L, D’Argenio G, Ciacci C, Daniele B, Macchia V & Mazzacca G (19 84) Diamine oxidase in rat ... endonuclease activation and apoptosis in thymocytes Exp Cell Res 19 5, 32 3 32 9 10 Saminathan M, Thomas T, Shirahata A, Pillai KS & Thomas TJ (2002) Polyamine structural effects on the induction and stabilization ... that interconvert and catabolize polyamines [33 ,34 ] A key enzyme for polyamine catabolism is diamine oxidase, which is able to bind the DNA and oxidize DNAbound polyamines [35 ] The fact that...

Ngày tải lên: 23/03/2014, 15:20

... damage and skin cancer in albinos in northern Tanzania: findings in 16 4 patients enrolled in an outreach skin care program J Am Acad Dermatol 19 95, 32 :6 53- 658 Yakubu A, Mabogunje OA: Skin cancer ... Med Assoc 19 81, 73: 10 47 -10 54 16 Luande J, Henschke CI, Mohammed N: The Tanzanian human albino skin Natural history Cancer 19 85, 55 :18 23- 18 28 17 Asuquo ME, Ebughe G: Cutaneous cancers in Calabar, ... cancer in African albinos Acta Oncol 19 93, 32 :6 21- 622 10 Kromberg JG, Castle D, Zwane EM, Jenkins T: Albinism and skin cancer in Southern Africa Clin Genet 19 89, 36 : 43- 52 11 Higgenson J, Oettle AG:...

Ngày tải lên: 09/08/2014, 03:22

... manifestations Hepatotoxicity Lactic acidosis Abnormal fat accumulation 48 41 11 10 2 38 .7 33 .1 8.9 8 .1 5.6 1. 6 1. 6 13 . 1 4.6 4.4 5.7 9.8 - 5.9– 23. 6 3. 6– 13 . 0 4.0 16 .6 3. 1 12 .1 4 .3 12 .6 - Gynecomastia ... purposes) AIDS Research and Therapy 2006, 3: 10 http://www.aidsrestherapy.com/content /3/ 1/ 10 HAART Pre-HAART HAART Pre-HAART 18 0 18 5 15 5 13 1 13 2 77 11 2 38 91 20 72 Figure curve according to adjusted Cox ... 77 11 2 38 91 20 72 37 11 Figure Arba Minch Hospital, 2006survival with and without HAART, Kaplan-Meier estimates of Kaplan-Meier estimates of survival with and without HAART, Arba Minch Hospital,...

Ngày tải lên: 10/08/2014, 05:20

... with avian influenza A H5N1 virus Lancet 19 98, 35 1: 467- 71 Page 12 of 13 (page number not for citation purposes) Respiratory Research 2005, 6: 13 5 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 ... (-◆-)c 30 46/04 (H5N1/04) (-×-)c 0.9 0.8 19 .2*b 15 .4*b 1. 6 1 .3 1. 7 1 .3 Not detectable 24 .1* b 16 .9*b 1 .3 0.9 26 .3* b 18 .7*b 46.8*b 29.7*b 54 /98 (H1N1) (-▲-)c -1 .3 8.8 *a 1 .3 1 .3 6.9 *a 1. 2 13 . 3*b 8 .1 *a ... (-■-)c 1. 1 7.4 *a -1. 2 1 17.4*b -1. 2 -1. 2 1. 55 1. 2 -0.8 -3. 5 18 .7*b -1 .3 22 .1* b 37 .9*b 0 .3 0.9 15 .1* b 9.9 *a 0.9 1. 1 0.8 1. 5 Not detectable 2.2* 9.5 *a 0.8 0.6 8.5 *a 4.7 *a 7.9 *a 6 .3 *a 11 94/04 (H5N1/04)...

Ngày tải lên: 12/08/2014, 18:20

... chỉ:http://www.microsoft.com /windows9 5/ Chọn mục: Downloads Cài đặt phiên cập nhật Critical Updates Recommended Updates Windows 98  Sử dụng chương trình cập nhật Windows: Microsoft Windows Update Menu Start Microsoft ... vào đ a sau để theo dõi thêm thông tin: http://www.cert.org/tech_tips/email_spoofing.html Wingate? Wingate package phổ biến cho phép máy tính mạng nội sử dụng chung đ a Internet Cấu hình Wingate ... Wingate chủ để che giấu vị trí thật họ Bạn vào đ a sau để xem thêm thông tin: http://www.cert.org/vul_notes/VN -98. 03. WinGate.html 10 Có thể tìm thông tin an toàn bảo mật máy tính đâu?    AusCERT...

Ngày tải lên: 31/07/2014, 18:20

... human 6622 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 a- amino-b-carboxymuconate-e-semialdehyde decarboxylase (ACMSD) J Biol Chem 277, 35 16 2 35 16 7 Tanabe A, Egashira Y, Fukuoka SI, Shibata K ... human ACMSD 10 11 12 13 14 15 16 17 18 19 20 S Garavaglia et al compounds in K562 cells but not in normal human lymphocytes Biosci Biotechnol Biochem 64, 11 42 11 46 Fernandez-Pol JA, Klos DJ & Hamilton ... on 32 6 Ca pairs hACMSD folds into 12 a- helices, 11 b-strands and connecting loops Residues 14 -48 form the small insertion domain that comprises a short a- helix and a three-stranded anti-parallel...

Ngày tải lên: 18/02/2014, 06:20

... classified diagrammatically into four separate metaphor categories This will be done in accordance to a classification that amalgamates Lakoff and Johnson (19 80), Lakoff (19 92), Gibbs (19 99) and Kovecses’ ... metaphor theorists (section 3. 3 .3) 83 An adaptation of Grady, Taub & Morgan’s (19 96) pictorial representation of metaphorical primitives and compounds in a diagrammatic arrangement (section 3. 3.2) ... metaphorical mappings from a source to a target are only partial as each source can only structure certain aspects of a target for analogy formation, metaphorical referencing and conceptual blending...

Ngày tải lên: 10/09/2015, 09:22

... (m2) B1 11 2,5 41, 4 B2 22 11 7,5 41 B3 11 6,5 63 B4 10 4 36 ,5 4,5 B5 16 11 8 38 7,5 B6 10 2,5 39 ,5 B7 10 2 70 7,5 B8 – 71 28,5 B8 – 2 71 28,5 10 B9 – 73 30,5 11 B9 – 73 30,5 12 B10 10 6 91 13 B 11 110 ,5 ... 0 ,33 2 15 ,38 0 ,16 7 10 5,4 70/60 Office 21 70 0,5 53 11 ,76 0 ,16 7 12 10 ,8 70/60 Café 21 70 0 ,33 2 0 ,16 7 10 5,4 80/80 Nhà hàng 21 70 0 ,33 2 0 ,16 7 12 5,4 94/66 Sảnh – T.Tân 21 70 0,202 15 ,38 0 ,16 7 12 ... 220,7 12 8,7 K 11 K.N.Hàng 1 220,7 12 8,7 K12 K.N.Hàng 2 91 106,2 K 13 Coffee 1 2 73 14 0 K14 P.M.Tính 60 0 K15 Sảnh 1- T.Tân 33 8,5 35 2,8 K16 Sảnh 14 1,2 90 K17 Coffee 288,6 1 63, 3 Diện tích cần điều h a 21...

Ngày tải lên: 26/04/2013, 16:38

... wishes she could come home May 10 , 2009 5.I can talk to you .10 a. m to 12 a. m 6.We should have dinner 11 a. m and 11 .30 a. m 1 .in/ in ; 2 .in ; 3. on ; on ; from ; between 1 In + tháng, năm, buổi ngày ... Exercise: Fill in; on;at;between; from in the gaps 1. I was bornJanuary 19 79.He was born 19 89 .the afternoon, we play badminton at school 3. If only he could visit me Suday/weekends 4.Lan wishes she ... is a shrine on the mountain near Ba,s village T 6.Everyone had a picnic on the mountain F 7.Everyone left the village late in the evening T 8.Liz had a videotape to show her trip to her parents...

Ngày tải lên: 01/07/2013, 01:25

... and 'a raise' in America raping or rapping? rape + ing = raping rap + ing = rapping See ADDING ENDINGS (i), (ii) rapt or wrapped? RAPT = enraptured (RAPT in thought) WRAPPED = enclosed in paper ... line of poetry 17 7 SCARCELY It can mean 'to look at all parts carefully in order to detect irregularities' (as in radar SCANNING and body SCANNING) It can mean to read intently and quickly in ... Highlands search seasonable or seasonal? SEASONABLE = normal for the time of year (SEASONABLE weather) SEASONAL = happening at a particular season (SEASONAL employment) secretary (singular) secretaries...

Ngày tải lên: 28/10/2013, 07:15

... Step 10 Verify that the serial connection is functioning a ping the serial interface of the other router BHM#ping 19 2 .16 8 .15 .1 GAD#ping 19 2 .16 8 .15 .2 b From GAD, ping the BHM router serial interface ... CCNA 2: Routers and Routing Basics v 3. 0 - Lab 3. 1. 5 Copyright  20 03, Cisco Systems, Inc Router Interface Summary Router Ethernet Ethernet Serial Serial Interface Model Interface #1 Interface ... contain one An example of this might be an ISDN BRI interface The string in parenthesis is the legal abbreviation that can be used in IOS command to represent the interface 5-5 CCNA 2: Routers and...

Ngày tải lên: 05/11/2013, 12:15

... computers in an organization and to decentralize administrative tasks Administrators perform the following administrative tasks: ! Senior administrators can delegate administrative tasks to other administrators ... administrator, which share a common directory database A domain has a unique name and provides access to the centralized user accounts and group accounts maintained by the domain administrator Security ... provide adequate availability and fault tolerance, whereas a large organization with many geographical locations needs one or more domain controllers in each location to provide adequate availability...

Ngày tải lên: 10/12/2013, 16:15