diverse roles of lipids in neonatal physiology and development

... Glucose and insulin tolerance tests 34 3.10 Body temperature measurement 35 3.11 Insulin and leptin measurements 35 3.12 Measurement of norepinephrine 36 3.13 Measurement of ... peripheral insulin resistance through AMPK pathway and insulin signaling pathway in vivo Diabetes Res Clin Pract 2011;93:205-14 83 Murase T, Misawa K, Haramizu S, Hase T Catechin-induced activation of ... 1.2 Role of dopaminergic system in energy balance and obesity 10 1.2.1 Dopamine, food reward and obesity 10 1.2.2 Dopamine and energy expenditure 16 1.3 Modulation of dopaminergic system

Ngày tải lên: 11/07/2021, 16:36

... biomass and starch have never been reported We are interested in identifying miRNAs and understanding miRNA functions in photosynthesis and starch accumulation in leaves and storage roots of cassava ... new-34 and W14 The corresponding primer sets are listed in Additional file Cloning and sequencing of the PCR amplicons of remnant mRNAs enabled determination of the nucleotide position when a slicing ... acted as a developmental regulator in the reprogramming of root cells during cyst nematode infection in Arabidopsis [33] These findings suggested that miR396 might regulate root development in cassava

Ngày tải lên: 27/05/2020, 00:45

... variability for minerals (iron and zinc content) among pearl millet germplasm, breeding lines and populations Therefore, an estimate of genetics and combining ability is important in selection of parents ... used in a breeding programme aimed at improving mineral contents, total carotenoids and grain yield The present investigation was undertaken to evaluate the nature of combining ability and standard ... density of mineral in grains through hybrid breeding Majority of crosses with high magnitude of significant and positive SCA effects involved the parents having one good and poor combiners for

Ngày tải lên: 13/01/2020, 23:14

... nucleus and the cytoplasm, and plays important roles in gene expression, including the following: (1) It assembles 20–24 bases upstream of each exon of pre-mRNA for its involvement in mRNA splicing ... regulator of stamen development [24] These findings indicate that the EJC participates in the regulation of pre-mRNA splicing in rice Despite the fact that the functions of homologs of MAGO and Y14 ... analysis of the interaction among rice MAGO, Y14, and eIF4AIII in onion epidermal cells N- and C-terminal fragments of YFP (YN and YC) were fused to the C-terminus of OsRH2, OsRH34, OsMAGO1, and OsY14b,

Ngày tải lên: 22/05/2020, 04:15

... ARTICLE Open Access Distinctive roles of syntaxin binding protein and its action target, TP63, in lung squamous cell carcinoma: a theranostic study for the precision medicine Erkhem-Ochir Bilguun1,2†, ... identification of LSCC-specific therapeutic biomarkers and/ or targets We previously found that Syntaxin Binding Protein (STXBP4) plays a crucial role in lesion growth and, therefore, clinical outcomes in ... (an isoform of tumor protein 63, TP63) ubiquitination and is an independent prognostic factor signifying a worse outcome in LSCC patients [10, 11] ΔNp63 is an isoform of TP63, a member of the TP53

Ngày tải lên: 05/11/2020, 08:23

... Training in CITI Preliminary training To facilitate the research assistants’ online training in CITI and IRB, the researcher will walk them through the English version of CITI and IRB online ... understanding of the material, where problems in understanding may occur Explanation and rechecking of understanding will be done in response to each problem that occurs Online training  The ... online training material before they register and start their online training in CITI In this preliminary training, the following steps will be taken:  The research assistants explain the material

Ngày tải lên: 04/05/2021, 23:09

... modulator of the light response in N crassa [15-17] It is a member of the LOV-domain subfamily of PER, ARNT and SIM (PAS)-domain proteins which mediate both ligand binding and protein-protein interactions ... cannot distinguish between direct and indirect influences of env1, since because of the lack of a known DNA-binding domain in ENVOY its effect is likely to be executed via protein-protein interaction ... deviation is indicated by bars into the H jecorina parent strain QM9414, resulting in strain 4env1qa+ Strains were grown in constant darkness and expression of env1 was induced by addition of quinic

Ngày tải lên: 02/11/2022, 11:35

... Bansal / Data in Brief (2016) 781–802 785 Fig Intra and Inter-helical salt bridges stabilizing 310-helices in membrane proteins a) The side-chain of 34Glu in the 310 helix (34E-36A) of TM2 in the Photosynthetic ... stabilization of the free backbone C¼ O atom by Cδ or Cγ atom of Proline and other intra-helical side chain to main chain (SM) hydrogen bonds Inter-helical interactions include SM hydrogen bonds from amino ... adopting curved and kinked geometries The data presented here supplements the article ‘Helix perturbations in Membrane Proteins Assist in Inter-helical Interactions and Optimal Helix Positioning in

Ngày tải lên: 24/11/2022, 17:46

... planning of new antitumor and antiviral drugs Natural products play an important role in the current scenario of research and advances in drug development In fact, since the beginning of humankind, ... c in the cytoplasm, in addition to inhibiting Akt phosphorylation in HepG2 cells, inducing intrinsic mitochondrial apoptosis and PI3K / Akt signaling pathways The polysaccharide induced an interruption ... 2018), with polysaccharides and glycoconjugates show incredible results in the development of antitumor drugs, in the development of vaccines and in the production of biomaterials such as hydrogels,

Ngày tải lên: 01/01/2023, 12:44

... enthusiasm, and support throughout the years of my studies The completion of this dissertation is mainly due to the willingness of Dr Csordas in generously bestowing me countless hours of advice and insight ... appreciation in allowing me to take part in honing my ability to understand our beloved theory of distribution of zeros of entire functions I appreciate everyone in the Mathematics department, but in particular, ... Macau, China, and the American Institute of Mathematics generously provided funding for travel and accommodation expenses in hosting the workshop “Stability, hyperbolicity, and zero location of functions”

Ngày tải lên: 10/03/2014, 16:15

... modification of the cofactorbinding site at the 8a-methyl group and at the linkage of the ribityl side chain Hence, as a first result, structural information regarding the distance and location of the ... proteins in which the two important histidines are individually replaced by alanine (His354Ala and His358Ala) were also examined at pH and 9.5 to identify the origin of the pH dependence of the ... changes in the binding pocket (and in the structural alignment of the two histidines) upon substrate binding cannot be ruled out As a second major result of the ENDOR study, the H(8a) ENDOR signal in

Ngày tải lên: 16/03/2014, 02:20

... are involved in recognition of the polyubiquitinated protein substrates, unfolding of the condemned protein [24], removing ubiquitin chains for recycling [25,26] and opening an axial gate into ... presence of proteasome, supporting the direct or indirect involvement of the flavin cofactor in protein complex formation [34] Mdm2 dependent polyubiquitination Fig Proposed mechanisms of ubiquitindependent ... speculation revolving around the physiological role of QRs The opinion that mammalian QRs are primarily involved in xenobiotic metabolism and in preventing the carcinogenicity and toxicity of highly

Ngày tải lên: 16/03/2014, 02:20

... profiles of auxin-induced genes in various tissues ⁄ organs and developmental stages of rice Fig S2 Expression profiles of auxin-repressed genes in various tissues ⁄ organs and developmental stages of ... representing hierarchical clustering of average log signal values of auxin-induced (A) and auxin-repressed (B) genes in various tissues ⁄ organs and developmental stages (mentioned at the top of each ... crosstalk between auxin and other plant hormones [21–24] Our study also shows that genes involved in cytokinin (e.g cytokinin-Oglucosyltransferase, cytokinin dehydrogenase, and response regulators),...

Ngày tải lên: 07/03/2014, 01:20

... residue in the L1 loop is involved in the functional DNA binding during strand exchange Tryptophan-scanning mutagenesis of the HsRad51-L1 loop To gain further information about DNA binding by ... Roles of the HsRad51 L1 and L2 loops D231W (L1 loop) Table Changes in the fluorescence of tryptophan probes inserted in the L1 and L2 loop upon binding of nucleotides and DNA The fluorescence of ... identified in these eukaryotic and archaeal proteins (Fig 1A) Like the case of bacterial RecA, the L1 and L2 loops of the eukaryotic Rad51 proteins face A Roles of the HsRad51 L1 and L2 loops inside of...

Ngày tải lên: 19/02/2014, 06:20

... resistance against IAV infection, independent of the glycoprotein makeup of circulating IAV strains The ectodomain of matrix protein (M2e) is a promising candidate for a broadly protective IAV vaccine ... Suzuki Y, Inoue R, Morishima T, Kondo N, Sata T, et al.: Roles of anti-hemagglutinin IgA and IgG antibodies in different sites of the respiratory tract of vaccinated mice in preventing lethal influenza ... those encoding H3 and N2 and is of low pathogenicity Immunization, infection and analysis of mice For i.n immunization, 50 μl of vaccine preparation (PBS containing μg M2e-MAP, μg ODN 1826 and 0.5...

Ngày tải lên: 18/06/2014, 18:20

... time of myocardial ischemia reperfusion The new information regarding the roles of NO and H2S in myocardial ischemia-reperfusion could deepen our understanding of mechanisms of reperfusion injury ... Identification of the molecular triggers, cell signaling pathways and underlying mechanisms involved in myocardial I/R injury will lead to a better understanding of the progress of ischemia heart disease and ... domain homologous to the cytochrome P450 reductases and an amino-terminal oxygenase domain containing a haem prosthetic group, which are linked roughly in the middle of the protein by a calmodulin-binding...

Ngày tải lên: 11/09/2015, 16:07

... Double staining with mRNA probe and immunohistochemical staining 2.3.8 DAPI staining 2.3.9 Mounting and photography 2.3.10 Confocal microscopy and imaging of living embryos after anesthetizing 54 ... expression of Tg(sst2:gfp) (line 1) during embryonic and early larva development GFP expression of Tg(sst2:gfp) in the intestinal cells during embryonic and early larva development GFP expression in ... specification in zebrafish Retinol binding protein (Rbp4) is the plasma transporter of retinol, the precursor of RA, and is mainly produced in the adult liver Except for delivering retinol from liver...

Ngày tải lên: 12/09/2015, 08:16