... components [18-21] Land plant expansins consist of two domains and a secretion signal The N-terminal expansin domain and the C-terminal expansin domain are homologous to the catalytic domain of ... bridges in fungal GH45 enzymes and maintaining their folded structure [16] were conserved inthe expansin domain of some of the plant expansin groups [22] and also inthe MdEXPs (Figure 5) In M ... of amino acids at conserved positions at either side of the HFDL motif inthe GH45 active site (a- and b-insertions) [16,43] According to the phylogeny, the MdEXPs contained an a-insertion characteristic...
... that able to interfere with AIV replication by inhibiting viral polymerases inthe nucleus and by binding viral components inthe cytoplasm The role of the Mx gene in resistance against influenza ... feed additives onthe humoral immune response induced by inactivated AIV vaccination in poultry has been studied Oral administration of ginseng stem-and-leaf saponins in drinking water or Hypericum ... response to vaccination against avian influenza in zoo-birds using an inactivated H5N9 vaccine Vaccine 2007, 25, 4345–4349 43 Robinson, J.H.; Easterday, B.C Avian influenza virus infection of the...
... three domains: an N -domain and two ATP-binding domains referred to as the D1 and D2 domains Interestingly, deletion of the N -domain from ClpA not only abolishes binding of the adaptor protein, ClpS, ... that the N -domain controls binding of ClpA to ClpP [14] Interestingly, there is also considerable debate regarding the role of the ClpB N -domain (which shares a common fold withthe N -domain of ... elements in ClpA, one inthe N -domain and the other inthe pore of the ClpA hexamer Inthe case of short unstructured peptides or unfolded proteins such as casein, binding to the tyrosine residues in...
... N-terminal NBD of P-glycoprotein contains only a single cysteine inthe Walker-A motif [43] Thus, MBP-NBD-Nter is a 75-kDa fusion protein containing a single cysteine residue located inthe ATP-binding ... on p[NH]ppA binding, in agreement withthe results obtained here The nonidentical interaction of GTP may be related to another variation in sequence inthe vicinity of the ATP-binding pocket, ... labelling was determined The data for the effects of nonadenine-containing nucleotides is shown in Table Of the compounds examined, the only nucleotide able to confer full protection against the...
... of the GAF domain are the potential ligands of the Fe-S cluster Consequently, the binding of the ATP analog and the subsequent rearrangement of the interdomain interaction affects the electronic ... cysteine residues, namely at position 107, at position 134 inthe GAF domain and at position 267 inthe possible AAA+ domain Accordingly, to determine which Cys are associated withthe binding ... changes inthe fragmentation depending onthe Fe-S cluster can be accounted for by a conformational change caused by the cluster formation in VnfA The variation inthe digestion patterns corresponding...
... compared withthe Cd4a species is due to expansion of the metal binding domain to accommodate the fifth Cd2+ This suggests that the additional Cd2+ ion is inserted into the core of the domain, becoming ... Cd4 binding site Finally, the NMR data verify the coordination of the fifth Cd2+ ion by thiolate ligands within the cluster, and, more specifically, within the crevice site of the protein The biological ... sequestering the ‘free’ ion upon cellular exposure Extraction of the Cd2+ ion from the affected protein results in liberation of the essential Zn2+ ion from the metallothionein pool; thus the metallothionein...
... similar structure to the corresponding region inthe VHL protein [15], which is also responsible for binding to elonginB ⁄ C Reports differ as to whether the interaction between elonginB ⁄ C and SOCS ... SH2 domain as in SOCS3 Other members of the SOCS family contain putative PEST sequences, but these are all located inthe N-terminal region, upstream of the SH2 domainThe conservation of the PEST ... linker inthe 22–185 construct As shown in Fig 4, the construct lacking the PEST region binds to the gp130 peptide ITC analyses showed that the titration curve could be fitted using a single binding...
... hippocampus is involved in Abinduced cognitive dysfunction [10] These findings together point to the need to increase our understanding of the role of MMPs in AD and their relation to other AD-related ... biomarkers Instead, they were used to employ correlations with other markers within each group and to define ‘individuals within the control group with increased risk for future AD’ The group ... be involved in both Abinduced neuronal dysfunction as well as in excitotoxic cell death inthe hippocampus The progressive neurodegeneration in AD precedes the decline in cognitive function and...
... Roaming between the IMS and the CS CN domain refers to inter -domain roaming between IMS and CS When a user is not registered or reachable in one domain a session can be routed to the other domain ... both online and offline charging capabilities Online charging is a charging process in which the charging information can affect in real time the service rendered and therefore directly interacts ... applications They are always -on- alwaysconnected application devices This redefines applications Applications are no longer isolated entities exchanging information only withthe user interface The...
... processing withthe intermediate symbols of alternative representation of images inthe compressed form instead of working with their original representations inthe spatial domain For example, in ... encoding of intermediate symbols considering their statistical distributions inthedomain of application As the techniques developed for these tasks are guided by information theory [52], they ... compressed domain If this algorithm takes longer time than its equivalent operation inthe spatial domain, the saving in computation of reconstruction and derivation of alternative representation (or inverse...
... myristylation sites inthe conserved MEME block and their conservation inthe years studied, in addition to its overlap with a single receptor binding site infers block importance in selective ... phosphorylation domain [10] 16 of the potential phosphorylation sites are Protein kinase C (PKC) phosphorylation site encompassing different regions of the protein The clustering of the PKC phosphorylation ... the location of each block within the HA sequence Notably, all of the blocks occur at least once within the HA1 domain (17–344) withthe exception of blocks and 14, which only occurs in HA2 Genetic...
... To determine the contribution of the individual cysteine residues inthe extracellular domain (ECD) to its functions, a panel of mutations in which each cysteine residue inthe ECD of the HRSV ... assess the effect of the cysteine mutations on protein expression, 293T cells were transfected with plasmids encoding either the wild-type F protein or those containing the individual cysteine mutations ... mutations had no gross effect on glycosylation These findings are intriguing given that these three cysteine residues are absolutely conserved not only inthe F proteins of other Pneumovirinae,...
... get a contradiction that the constant factor inthe reverse of 3.1 is not the best possible Thus the theorem is proved By the same way of Theorem 3.3, we still have the following theorem Theorem ... the constant factor in 3.1 is not the best possible Thus the theorem is proved Journal of Inequalities and Applications In view of Note and Theorem 3.1, we still have the following theorem Theorem ... which contradicts the fact that k λ < K Hence the constant factor k λ inthe reverse of 3.1 is the best possible If the constant factor in reverse of 3.2 is not the best possible, then by the reverse...
... section RESOLVING THE PERMUTATION AMBIGUITY Several ideas have been introduced to resolve the permutation ambiguity, as detailed inthe introduction The first one consists in constraining the separating ... tation correction in frequency -domain in blind separation of speech mixtures,” in Proceedings of the 5th International Conference on Independent Component Analysis and Blind Signal Separation ... spectral continuity of the mixing (and therefore of the EURASIP Journal on Applied Signal Processing unmixing) filters is used inthe initialization of the joint diagonalization algorithm The exploitation...
... simplify the notation, inthe following, we will drop the superscript (k) referring to the kth iteration of the deconvolution algorithm Blind Image Nonlinear Deblurring inthe Edge Domain 2465 Nonlinearity ... − 1, the global maximum and the global minimum, respectively, inthe Radon domain Therefore, for each point belonging to the direction βm and having index n, the nonlinearity (13) weights the ... nonlinear processing is designed inthe Radon transformed domainThe nonlinear processing is spatially variant, depending onthe detection of strong edges versus uniform or textured regions The...
... follows Thewatermarking system model is presented in Section Inthe next section, the signal model is presented and the distribution of DFT magnitude coefficients is shown Then, in Section 4, the construction ... (k) denote the real and the imaginary part of S(k), respectively As mentioned inthe introduction, the watermark embedding is performed inthe Fourier domain and more specifically in its magnitude ... DISTRIBUTION OF DFT MAGNITUDE COEFFICIENTS A basic step for the optimal detector construction is the computation of thetransform coefficient distribution Thus, in this section, the distribution of the...
... sustainability 2.7 Representation and Rights inthe Provisions of the Thai Constitution and the Environment Act The ratification of declarations invoking the rights of the public participation, ... environmental protection, and was first defined as a principle of international environmental policy in 1987 withthe Second North Sea Treaty: Since then, the precautionary principle has become intrinsic ... ecosystems on a national and global level.21 The developing nations inthe region continue to struggle with fossil-fuel induced pollution, one of the consequences of an accelerated urban economy Energy...
... a basis for the determination of conditions the fulfilment of which leads to the optimization based onthe determination of the minimum heterogeneous substance emissions related to the performance ... inthe selection of appropriate and environment-friendly technologies including the choice of suitable machinery, and in using acceptable methods for the employment of machines withthe rational ... operations); By extending the working assembly (e.g extension of the cutting mechanism length – cutter bars); – By extending the cross sections within roads where the material is transported; – By increasing...
... is monochromatic and the other edges are rainbow In each coloring, it is clear that there is no rainbow k-matching However, if there are more colors than in these colorings, is there a rainbow ... without rainbow k-matchings Inthe coloring (a) of Figure 1, a complete subgraph K2k−3 of G is rainbow and the other edges are colored with exactly one color, namely, monochromatic Inthe coloring ... this conjecture holds for ≤ k ≤ in our preprint (we can send the proof upon request), but for k ≥ this is still open The concept of rainbow matchings is linked withthe relationship between the...
... Now, continuing with +2 would miss Onthe other hand, continuing with −2 would give us an imperfect realization of {22 , 32 } the electronic journal of combinatorics 17 (2010), #R44 Another possibility ... another This means that we are forced to start with +3 and continue until we obtain the whole 0-class After which we may either continue with −2, −3, or with +2, −3, Inthe first case we continue ... {1, 2} The first string of +3’s must exhaust the 0-congruence class and therefore we reach up to the vertex 3k + The second string of −3’s will describe another congruence class in decreasing order...