different rules in forming the plural form of singular nouns

... structural domains, while proCPY would be composed of a single fragile domain. The propeptide of the proenzyme would be located at the interface of the two domains thus combining them into one body, ... that the cleft of the active site will be located in the interface between the two structural domains of CPY and would be filled by the propeptide, thus uniting the two domains in a body, as if the ... peak (Fig. 1A), indicating that the thermal unfolding process of the precursor form follows a two-state transition. The ratio of the unfolding enthalpy (DH cal )tothe van’t Hoff enthalpy (DH v )...

Ngày tải lên: 07/03/2014, 21:20

... 3325 Isothermal unfolding studies on the apo and holo forms of Plasmodium falciparum acyl carrier protein Role of the 4Â-phosphopantetheine group in the stability of the holo form of Plasmodium ... 4Â-phosphopantetheine that rmly maintain the structure of the holo form. We show here for the rst time that the interactions between 4Â-phosphopantetheine and the polypeptide backbone of acyl carrier protein ... with the LEM of protein unfolding [29]. It is apparent from the solution denaturation studies that the holo form of the protein has greater stability than the apo form. The differences in the...

Ngày tải lên: 16/03/2014, 10:20

Ngày tải lên: 21/07/2014, 21:20

... exist in the SL only; there is no equivalent in the TL. Similarly, a term in the SL and the one in the TL often accorded to it are not identical in terms of conceptual meaning. For example, in the ... precise, limiting the chances of the provision being misinterpreted. The participants, therefore, are clearly aware of the circumstances of their rights and obligations. The noun phrase in 6.(2/1): ... (Trosborg, 1997: 145-146 in Garzone). Every version of the documents in any of the official languages of the issuing international agency is supposed to have the same meaning as other versions, and...

Ngày tải lên: 07/11/2012, 14:36

Ngày tải lên: 26/12/2013, 01:18

... in a snake. 14. My brother managed to kill the snake just at the time when I were almost exhausted. Supply the correct form of the verbs 1. Cats could fly if they (have) wings. 2. If Peter (study) ... live in a snake. 14. My brother managed to kill the snake just at the time when I (be) had been almost exhausted. If he (be) had been a little late, I (kill) would have been killed by the snake. 15. ... got wet if she had worn a raincoat. 5. If today were a holiday, I would stay in bed for all day long. 6. If she made him change his mind, she would save him a lot of trouble. 7. I wish he would...

Ngày tải lên: 23/01/2014, 07:20

... and grow the facility division of our business, as well as moving things in ‘‘brown boxes.’’ The integrity of a company is based on the integration of the firm’s values into its driving systems. ... still looking for a modern-day mentor to bounce ideas off of and, like other women at the top of their profession, sees the loneliness of the position as one of the few downsides to the job. Although ... success. They did business plans but they were also gifted improvisers, more focused on improving the future than correcting the past. They placed values at the center of their businesses and they...

Ngày tải lên: 14/02/2014, 04:20

... percent of the county’s 3,000 miles of sewer lines are combined with storm sewers; most of these predate the 1950s, particularly those in the county’s oldest neigh- borhoods. In Cincinnati, ... with swimming in sewage-contaminated marine waters. 59 The amount of human illness after exposure to marine water appears to be increasing, and there is evidence that the rate of infection ... 860,454. The city is situated in the upper part of the White River watershed—a system of rivers draining more than 11,000 square miles of central and southern Indiana. Major tributaries flowing into...

Ngày tải lên: 17/02/2014, 10:20

... biological function of the pro -form of bone morphogenetic protein-2 (BMP-2), a member of the transforming growth factor b (TGFb) ⁄ BLP superfamily. The role of the 263 amino acids of the pro-peptide ... with the noggin-binding area [32,42]. Thus, the proBMP-2 binding to noggin detected here indirectly confirms the interaction of proBMP-2 with BMPR-IA. Conversely, as noggin cov- ers part of the ... to the ECD of BMPR-IA. Furthermore, the results indicate that both proteins interact with the same epitope on the ECD because proBMP-2 binding can be inhibited by BMP-2. To assess binding of...

Ngày tải lên: 18/02/2014, 06:20

... determined by a number of fac- tors, including the rate of unfolding, the amino acid sequence of the protein, the experimental conditions and the nature of the intermediate state(s) that form [1,2]. ... state). In con- trast, arginine has been shown to suppress aggregation of some proteins by acting on the unfolded state of the protein and increasing the reversibility of unfolding [37]. Arginine ... increase the activity of aB-crystallin against DTT-induced precipi- tation of insulin at intermediate and high concentra- tions, and it also increased the activity of aB-crystallin in preventing the...

Ngày tải lên: 18/02/2014, 16:20

... suggesting both these elements are of equal importance for the formation of amyloid from the C110)131 peptide. Role of the NH 2 -terminal sequence The role of the NH 2 -terminal sequence of the ... studies with the peptides lacking the residues 110–113 (excluding the two valine amino acids), showed a decrease in the formation of amyloid fibrils, suggesting the importance of the hydropho- bic ... NH 2 -end of the peptides. In the same way, removing the CONH 2 -terminus of the peptides resulted in increased amyloid fibril formation. This increase may be due to a direct inhibitory effect of this...

Ngày tải lên: 21/02/2014, 01:21

... from the internal b-sheet of the b-sand- wich domain. The last four amino acids of the native sequence at the C-terminus and the His-tag protrude from the b-sandwich domain and interact with the ... blades in the axis area are of polar character. The water channel in the apo form of the enzyme runs along the axis of the b-propeller through the whole domain and is only blocked by Cys236 in the ... the b-sheet domain is postulated as an inulin-binding site. Unlike in other GH32 fam- ily enzyme structures known to date, the cleft formed between the b-propeller and the b-sheet domain in the...

Ngày tải lên: 06/03/2014, 00:21

Ngày tải lên: 07/03/2014, 02:20

... occupancy of the first binding site [68]. TTR is also involved in the transportation of retinol by forming a complex with the smaller retinol- binding protein (RBP) [69,70]. The TTR–RBP–retinol complex ... strands and the intervening loop forming a large loop, expos- ing some hydrophobic residues in this region that are normally buried on the inside of the protein [98]. Dis- location of the C and ... Thyroxine-induced con- formational changes in prealbumin. Biochemistry 17, 5729–5733. 69 Kanai M, Raz A & Goodman DS (1968) Retinol-bind- ing protein: the transport protein for vitamin A in human...

Ngày tải lên: 07/03/2014, 10:20

... carrying out the labelling procedure without primary antibody. The efficiency of blocking was controlled by performing the labelling procedure in the absence of the second primary antibody. The ... treatment, (b) correlation of the interaction with phosphorylation of Ser5 of the C-terminal domain hepta- peptide repeat, and (c) the ability of C-terminal domain kinase inhibitors to abolish it. ... iod- ide-stained cells [65] in parallel cell cultures. Where indi- cated, cells were cultured in the presence of the indicated concentrations of one of the following inhibitors: 20 lgặmL )1 a-amanitin,...

Ngày tải lên: 07/03/2014, 11:20

... isoforms of the endogenous protein kinase inhibitor of cAMP-dependent protein kinase in mouse. J. Biol. Chem. 268, 10927–10931. 10. Olsen, S.R. & Uhler, M.D. (1991) Inhibition of protein kinase-a ... regulation of the PKI and PKI isoforms of the inhibitor protein of the cAMP-dependent protein kinase. J. Biol. Chem. 272, 20011–20020. 20. Byler, D.M. & Susi, H. (1986) Examination of the secondary structure ... studies of the catalytic subunit of the cAMP-dependent protein kinase. Its ability to readily alter the PKI coding sequence could permit further studying of human PKIb and understanding of the function...

Ngày tải lên: 07/03/2014, 15:20

Ngày tải lên: 23/03/2014, 15:21

Ngày tải lên: 23/03/2014, 15:21