... reports have indicated that MVP is tyrosine phosphorylated in vivo in CHO and PC12 cells and phosphorylated by PKC and casein kinase II in vitro using specific kinase agonist and inhibitors [31,32] ... binding of MVP with Src MVP is known as a phosphoprotein as it is tyrosine phosphorylated in vivo and phosphorylated by protein kinase C (PKC) and casein kinase II (CKII) in vitro [28,29] To investigate ... activity Domains within Src kinases target the enzyme to specific subcellular locations where they bind to regulatory and ⁄ or substrate proteins and are integrated into cell signalling pathways and cell...
Ngày tải lên: 07/03/2014, 12:20
Báo cáo khoa học: Functional interplay between viral and cellular SR proteins in control of post-transcriptional gene regulation pptx
... function in pre-mRNA splicing Indeed, an EV HPV E2 protein interacts with cellular splicing factors, including prototypical SR proteins and RS domain-containing small nuclear ribonucleoprotein (snRNP) ... carcinoma The HBV core protein plays several roles during the viral life cycle, including positive-strand and minus-strand DNA synthesis, pre-genomic RNA packaging, and virion formation and release ... kinases, including cyclin-dependent kinases, GSK, casein kinase II, mitogen-activated protein kinases, and SRPKs, may phosphorylate coronavirus N proteins [11,12] We have Several viral proteins...
Ngày tải lên: 23/03/2014, 06:20
INCENTIVES AND TEST-BASED ACCOUNTABILITY IN EDUCATION doc
... Incentives and Test -Based Accountability in Education INCENTIVES AND TEST -BASED ACCOUNTABILITY IN EDUCATION Committee on Incentives and Test -Based Accountability in Public Education ... Incentives and Test -Based Accountability in Education INCENTIVES AND TEST -BASED ACCOUNTABILITY IN EDUCATION research review points to five key choices that should be considered in designing incentive ... reserved Incentives and Test -Based Accountability in Education INCENTIVES AND TEST -BASED ACCOUNTABILITY IN EDUCATION these features are likely to be critical in determining which—if any—incentive...
Ngày tải lên: 23/03/2014, 12:20
Báo cáo khoa học: NrpRII mediates contacts between NrpRI and general transcription factors in the archaeon ¨ Methanosarcina mazei Go1 pot
... contains a sole NrpR consisting of one single NrpR domain with a N-terminal HTH domain [26], it is of specific interest to elucidate whether the single NrpR domain of M kandleri is also binding ... each time using 300 lL of protein-binding buffer (see above) Potentially DNA-bound proteins were subsequently eluted step-by-step using 200 lL of binding buffer containing increasing amounts ... domain (e.g M maripaludis NrpR); one with a single NrpR domain and an N-terminal HTH domain (e.g NrpRI of M mazei and M acetivorans); and one with a single NrpR domain (e.g NrpRII of M mazei and...
Ngày tải lên: 29/03/2014, 21:20
báo cáo sinh học:" Agreement between physicians and non-physician clinicians in starting antiretroviral therapy in rural Uganda" docx
... training of the clinical team Sites in Masaka district in southwest Uganda, for example, were the first to be trained, in June 2004, whereas other sites in northern Uganda received training in ... by the Ministry of Health to standardize nursing training and to reduce the wide variation in education and training between nurses working at government health units, particularly those in rural ... workers were trained in delivering chronic HIV care and treatment during the period from June 2004 – when IMAI training was first conducted in Uganda by WHO and the Ministry of Health – and June 2006...
Ngày tải lên: 18/06/2014, 17:20
báo cáo hóa học: " Can we derive an ''''exchange rate'''' between descriptive and preference-based outcome measures for stroke? Results from the transfer to utility (TTU) technique" doc
... difference between instruments arises due to out-right errors that might be reflected in the reliability of each instrument (or lack thereof) and/ or due to any between- instrument difference in ... using item weighting and additive scaling, to yield a 0–100 point scale These eight dimensions can be combined into two summary measures – physical function (PCS index) and mental health (MCS index), ... predict an individual's AQoL score We calculated MADs by taking the absolute difference between predicted and observed scores for each individual, summing over all individuals, and dividing through...
Ngày tải lên: 18/06/2014, 18:20
báo cáo hóa học:" Poor Efficacy and Tolerability of Stavudine, Didanosine, and Efavirenz-based Regimen in Treatment-Naive Patients in Senegal" potx
... bilirubin, and creatinine) were performed at baseline, weeks and 4, and every months thereafter for 18 months Blood triglycerides, total cholesterol, and glucose were measured at baseline and months ... sepsis In a comparison of patients treated in industrialized and poor countries, a large difference in mortality was noted during the 12 months following the initiation of HAART This was linked ... abandoning d4T later in treatment is still to be determined in cohorts 80 73 VL < 50 c/mL VL < 500 c/mL 70 56 60 50 % of Patients tating and intolerable discomfort requiring a switch from ddI and...
Ngày tải lên: 20/06/2014, 08:20
báo cáo hóa học:" Do diabetes and depressed mood affect associations between obesity and quality of life in postmenopause? Results of the KORA-F3 Augsburg population study" pdf
... risk in obese women aged 45 to 74 years Considering these findings and the pathophysiological cluster including visceral fat, depressive and metabolic disorders [15], the present study investigates ... computer-aided personal interview (CAPI), a self- Page of 10 administered questionnaire, physical examination by trained personal (including assessments of body weight and height) and blood sampling The sample ... US finding no associations between obesity and depression [28] Moderating effects of depressed mood and diabetes on the relation between obesity and HRQL depended on Heidelberg et al Health and...
Ngày tải lên: 20/06/2014, 15:20
Báo cáo hóa học: " Evaluating interaction forces between BSA and rabbit anti-BSA in sulphathiazole sodium, tylosin and levofloxacin solution by AFM" potx
... concentration increased, hence diminishing the strong repulsive protein-protein interactions In addition, increasing the solution IS may disrupt the hydration shell coating on protein surfaces and thus ... polymyxin B affected the molecular interaction between lipopolysaccharide (LPS) binding protein-LPS complex and the receptor protein using AFM and different structures of the drugs resulted in different ... and Technology, Ministry of Education, Chongqing University, 400044 Chongqing, China 2Institute of Biochemistry and Biophysics, College of Bioengineering, Chongqing University, 400044 Chongqing,...
Ngày tải lên: 20/06/2014, 22:20
Báo cáo hóa học: " Research Article Performance Optimization for Delay-Tolerant and Contention-Based Application in IEEE 802.16 Networks" pptx
... uplink data throughput and the pending competitive bandwidth requests in uplink channel by efficiently combining request and grant allocation strategies together In our analysis, we introduce a random ... synchronization and equalization The DL-MAP and UL-MAP contain the correlative information of the intervals’ usage in the following downlink and uplink subframes, respectively, and are broadcast ... request uplink bandwidth before transmitting data in a corresponding bandwidth grant This means that if an SS wants to uplink transmission, it first sends a request to BS during the polling interval...
Ngày tải lên: 21/06/2014, 23:20
Báo cáo y học: "The relationship between inflammation and new bone formation in patients with ankylosing spondylitis" docx
... syndesmophytes in the upper and lower edges of L1/L2 and L2/L3 (a) T1-pre-gadolinium (T1-pre-Gd) image Spinal inflammation syndesmophytes in the upper and lower edges of L1/L2 and L2/L3 in the same ... that spinal inflammation and new bone formation are both uncoupled and linked in AS since (a) the majority of syndesmophytes developed without MRI evidence of spinal inflammation at BL and (b) ... and the lumbar spine in the lateral view at BL and 2yFU were taken Because of the known technical problems in the assessment of the thoracic spine in standard x-rays [4], this part of the spine...
Ngày tải lên: 09/08/2014, 13:21
Báo cáo y học: " The contrasting roles of PPARδ and PPARg in regulating the metabolic switch between oxidation and storage of fats in white adipose tissue" ppt
... both pathways; the enzyme introduces the initial double bond into linoleate forming g-linolenate in the ω-6 pathway and introduces the double bond into linolenate forming stearidonic acid The ... an increase in the concentrations of citrate and succinate and decreases in fumarate and malate The 1-13C glucose labeling experiment and increased citrate concentration demonstrate that the increased ... relative doses and regimes, and so the effectiveness of short term lipid lowering in blood plasma may be variable The detected increase in certain TAGs containing C16 and C18 saturated and monounsaturated...
Ngày tải lên: 09/08/2014, 23:20
Báo cáo y học: "The association between microvascular and macrovascular endothelial function in patients with rheumatoid arthritis: a cross-sectional study" pdf
... eliminated when 0.5% sodium chloride is used [44], as in the present study Thus, differences in protocol make comparing the findings of both studies difficult In the present study, differences in ... UK) according to previously established guidelines [41] Following ten minutes of rest, endothelium-independent responses were examined by administration of a 500-μg sublingual glyceryl trinitrate ... function in healthy individuals have reported mixed findings, with some reporting an association between microvascular and macrovascular endothelial-dependent function [22,23] and others reporting...
Ngày tải lên: 12/08/2014, 17:21
Báo cáo y học: " The conserved dileucine- and tyrosine-based motifs in MLV and MPMV envelope glycoproteins are both important to regulate a common Env intracellular trafficking" doc
... fixation and staining A Co-staining of CD25 chimeras and Mannose 6-phosphate receptor of 46 kDa (MPR46), a protein that accumulates in the TGN at steady state B Co-staining of CD25 chimeras and internalized ... the CD25-MLV and the CD25-MPMV chimeras in the TGN required both the dileucine -based motif in position and the tyrosinebased motif in position 23 By contrast, the tyrosine -based motif in position ... possesses dileucine- and tyrosine -based motifs that drive its trafficking in a TGN-endosome cycling pathway (Blot et al, unpublished data) Finally, the tyrosine -based motifs in position 23 in the cytoplasmic...
Ngày tải lên: 13/08/2014, 09:20
Báo cáo y học: " Potential applications of curcumin and its novel synthetic analogs and nanotechnology-based formulations in cancer prevention and therapy" pps
... cancer cells and antitumoral effect on MDA-MB-231 cell xenografts in vivo by inhibiting p21WAP1, survivin and NF-B and its downstream effectors, including cyclin D1 and Bcl-2, and activating caspase ... cell lines and those detected in the patients in clinical settings Clinical trials of curcumin The results from phase I/II clinical trials including the dose-escalation studies with pure curcumin ... [212] In addition, this difluorinated curcumin analog or CDF was more effective than curcumin at inhibiting the sphereforming ability and increasing pancreatosphere disintegration of parental and...
Ngày tải lên: 13/08/2014, 14:20
Báo cáo sinh học: "Genetic interaction between sire and population of mates in Drosophila melanogaster" pps
... which the interaction may be in one case, as a change in the ranking of sires, or in another, as a difference in variance between the purebred and crossbred progeny Should a large genetic interaction ... reduce selection intensity and increase generation interval In this study, progeny variances were analysed to estimate genetic parameters including the genetic correlations between pure and crossbred ... strain and the tester stock a white-eyed mutant strain Both stocks were maintained as separate random mating populations At intervals of less than 12 h newly emerged flies were separated into...
Ngày tải lên: 14/08/2014, 19:22
The difference between saigon and hanoi
... level Fifth level In winter months cold and dry usually cloudy and foggy and less rain IN SUMMER HOT , HUMID AND RAINY 1,680 millimetres of rainfall SAI GON THE RAINY THE DRY the rainy season Click ... ,iced tea and lemon tea Sitting and drinking between cool air and tranquil views of a coner in ancient Ha Noi On sunny or rainy day , in summer or winter Many people think lemon tea is just suitable ... biggest city in VietNam, is famous for a big buildings and giant malls - Traffic in Ho chi minh’s order than in Hanoi Even during rush hour, or normal, cars and motorcycles are still going on right...
Ngày tải lên: 28/11/2014, 11:37
Social Media and Internet-Based Data in Global Systems for Public Health Surveillance A Systematic Review
... systems InSTEDD and GPHIN incorporate human input and review, allowing users to add comments, tags, and ranks during the data-processing phases and confirmation and feedback during the dissemination ... 11 TABLE Indicator -Based and Event -Based Surveillance Systems Indicator -Based Event -Based Timeliness of Data Input Information is input as soon as it is made available Timing is set immediate/ ... lag between the occurrence of an event and the indicator -based surveillance That is, data input and retrieval for indicator -based surveillance often rely on specific case definitions and reporting...
Ngày tải lên: 08/04/2015, 17:20