dietary intakes of ascorbic acid in physically active persons
Báo cáo Y học: Role of tyrosine 238 in the active site of Rhodotorula gracilis D-amino acid oxidase A site-directed mutagenesis study docx
Ngày tải lên :
17/03/2014, 17:20
... for Y223 in binding and xation was suggested [4] This proposal was changed recently following the investigation of the effect of pH on benzoate binding in RgDAAO [12] and the resolution of the ... (retaining their FAD prosthetic group) The mutants, in their oxidized state, show the typical spectrum of the FADcontaining avoproteins (line in Fig 2), an extinction coefcient at 455 nm of % ... band at % 600 nm following the binding of anthranilate (Fig 3, inset) and the shoulder at % 500 nm following the binding of benzoate (De497nm of 7500ặM)1ặcm)1 vs a gure of 2000 4000ặM)1ặcm)1 observed...
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báo cáo hóa học:" High dose concentration administration of ascorbic acid inhibits tumor growth in BALB/C mice implanted with sarcoma 180 cancer cells via the restriction of angiogenesis" potx
Ngày tải lên :
18/06/2014, 15:20
... concentration of ascorbic acid In our recently published works, intraperitoneal administration of a high dose concentration of ascorbic acid quantitatively up-regulated Raf kinase inhibitory protein (RKIP) ... fat-soluble active oxygen by reducing vitamin E In addition, ascorbic acid prevents the formation of carcinogenic nitrosamines by reducing nitrates through the NAD (nicotinamide adenine dinucleotide)-dependent ... recovered in NIH3T3 cell at 12, 24, 36 hrs by cell migration even in ascorbic acid in 2.5 mM and ascorbic acid in 10 mM (Figure 6) Therefore, migration was inhibited according to ascorbic acid concentration...
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Báo cáo khoa học: " Influence of ascorbic acid on BUN, creatinine, resistive index in canine renal ischemia-reperfusion injury" pps
Ngày tải lên :
07/08/2014, 18:21
... hguohtla ,yduts ruo nI ]8[ slevel NUB dna rC eht ni esaercni tnacifingis a yb detacidni si hcihw noitartlif raluremolg eht ni esaerced eht rof sisab eht eb ot deredisnoc si hcihw elubut eht fo nemul ... esaercni tpurba detartsnomed nim 09 rof aimehcsi gniwollof noisufreper laner ,yduts suoiverp a nI puorg lortnoc ni detartsnomed erew noisufreper retfa syad 41 dna erofeb yletaidemmi seulav erapmoc ... tnereffid tnacifingis ton erew ,noitcnuf yendik fo xedni na sa derusaem ,slevel rC mureS stnemirepxe eht gnirud aimeru fo sngis lacinilc on dah spuorg htob fo sgod llA stluseR tnacifingis yllacitsitats...
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Báo cáo khoa học: "Attenuation of ischemia-reperfusion injury by ascorbic acid in the canine renal transplantation" pps
Ngày tải lên :
07/08/2014, 18:21
... a rof nekat erew yendik tfel eht morf selpmas eussit ehT ld/gm 8.1< ot dezilamron dah seulav eninitaerc mures eht fi keew tnalpsnart-tsop driht eht retfa seninac gnivivrus eht gnizinahtue rof ... syendik ehT seimotcerhpen eht erofeb nim 02 )aeroK ,mrahP naH iaD ;VI ,gk/g 1( lotinnam deretsinimda erew sgod ehT )VI ,h/gk/lm 01( noitulos etylortcele decnalab a deretsinimda erew sgod eht llA erudecorp ... ,snouH ;CS ,gk/gm 40.0( etaflus eniporta htiw detacidemerp era slamina eht ,tsaf thginrevo na retfA la te noitatnalpsnarT noitatnalpsnartotua yb dewollof puorg tnemtaert eht ni desufrep erew )aeroK...
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Tài liệu Reducing Stress Fracture in Physically Active Military Women doc
Ngày tải lên :
14/02/2014, 04:20
... training; AIT, advanced individual training; OSUT, one-station unit training; RTC: recruit training command; MCRD, Marine Corps recruit depot; BMT, basic military training; FTU, fitness training ... load-bearing conditioning hikes; and modification of the scheduling of different physical training events to maximize training benefit and minimize the risks of overtraining and overuse injuries ... fitness, a training program must include a history of sufficient loading and remodeling within bone if stress injuries and fractures are to be prevented during periods of intense training Proper...
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Báo cáo khóa học: Mutational and computational analysis of the role of conserved residues in the active site of a family 18 chitinase docx
Ngày tải lên :
07/03/2014, 14:20
... formation of the oxazolinium ion intermediate; (C) Hydrolysis of the oxazolinium ion intermediate Copyright National Academy of Sciences, USA questioned on the basis of studies of chitinase A from ... of the )1 sugar ring into a 4-sofa conformation is an inherent part of the catalytic mechanism (Fig [17,19,21,22]) Structural studies show that Asp142, Tyr214 and Asp215 are involved in binding ... most active The basic arm of the pH-activity profile must be determined by the loss of one or both of these protons Comparison of rows 1, and with rows and in Table shows that substrate-binding...
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Báo cáo khoa học: Kinetic and crystallographic analyses of the catalytic domain of chitinase from Pyrococcus furiosus – the role of conserved residues in the active site pdf
Ngày tải lên :
15/03/2014, 11:20
... bioconversion of chitin into valuable oligosaccharide derivatives for various industrial applications Pf-ChiA has a unique multidomain structure containing two chitin-binding domains (ChBD1 and ... number of amino acid residues contribute to the binding of the substrate by hydrogen bonding and ⁄ or hydrophobic interactions Using the ligplot program [31], we investigated the specific interactions ... degree of sequence similarity The catalytic domain of family 19 chitinases comprises two lobes, each of which is rich in a-helical structure [16,17] In contrast, family 18 includes chitinases...
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báo cáo hóa học:" Anti-angiogenic effect of high doses of ascorbic acid" pptx
Ngày tải lên :
18/06/2014, 15:20
... time of exposure were established The infusion of 15 g of ascorbic acid in 45 raised the plasma level of AA to 120 mg/dl with a decrease to half intensity after hours A 30 g infusion Page of 10 ... different concentrations of AA during 3–6 hrs Number of intact loops in wells treated by ascorbic acid was normalized on the number of intact loops in control wells Page of 10 (page number not ... acid increase the availability of ascorbic acid radicals, resulting in reaction of ascorbic radical with NO In addition, oxidation of tetrahydrobiopterin, which is a cofactor for endothelial NOS,...
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a large scale, multicentre, double-blind trial of ursodeoxycholic acid in pts with chronic hepatitis c 2007
Ngày tải lên :
13/08/2014, 09:44
... prevalence of hepatitis C virus (HCV) infection increased recently in several countries1 and has now resulted in a growing incidence of HCV-related hepatocellular carcinomas.2 Following the discovery of ... ethics committee of each institution participating in the study Patients were informed of the details of the clinical study and agreed to participate We conducted this clinical study in accordance ... subgroup of baseline GGT>80 IU/l showed a significantly lower level of GGT with 900 mg/day administration (p = 0.004) Bile acid in serum Total bile acid concentration in serum increased in a dosedependent...
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Pharmacokinetics and pharmacogenetics of mycophenolic acid in asian renal transplant patients in singapore
Ngày tải lên :
12/09/2015, 08:18
... protein binding of MPA .76 3.3.3.2 Human plasma protein binding of MPAG 76 3.3.3.3 Effect of MPAG on human plasma protein binding of MPA77 3.3.3.4 Effect of MPA on human plasma protein binding ... dose reduction or elimination of corticosteroid, (ii) dose minimization or withdrawal of calcineurin inhibitor, or (iii) substitution of calcineurin inhibitor with SRL in patients who are particularly ... Prednisone Inhibit expression of cytokines, namely interleukin-1, -2, -3, -6, tumor necrosis factor- and interferon- , resulting in the inhibition of all stages of T-cell activation Maintenance...
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A study into the different mechanisms of anti cancer effect of docosahexanoic acid in colon cancer cells
Ngày tải lên :
26/09/2015, 09:57
... Modifying Factors in Asian Indian and Chinese Males Nutrition In press • Manav, HM Shen and CN Ong Involvement of c-Jun N-terminal kinase activation in Docosahexanoic acid- induced apoptosis in colon ... signaling pathways in DHA-induced apoptosis in colon cancer (4) To study the role of oxidative stress in activation of MAPKs and induction of apoptosis by DHA (5) To examine the role of PPARγ in ... Administration of low doses of DHA to ACI/T rats transplanted with Morris 13 hepatocarcinoma 3924A resulted in doubling of the number of cells undergoing apoptosis, whereas administration of...
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Pharmacokinetic and pharmacodynamic studies of mycophenolic acid in renal transplant recipients
Ngày tải lên :
28/11/2015, 13:44
... objective of identifying the pharmacokinetic profile of total and free mycophenolic acid (MPA), and mycophenolic acid glucuronide (MPAG) and pharmacodynamic profile of MPA in mycophenolate mofetil ... Pharmacokinetic parameters of mycophenolic acid in different transplant groups of multiple doing reported in literatures 20 Pharmacokinetic parameters of MPAG in different transplant groups of multiple ... concentration-time profile of total MPA in patients for conventional study following chronic oral dosing of MMF after fitting in two compartment model 117 Plasma concentration-time profile of free MPA in patients...
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Báo cáo khoa học: Polysaccharide binding sites in hyaluronate lyase – crystal structures of native phage–encoded hyaluronate lyase and its complexes with ascorbic acid and lactose docx
Ngày tải lên :
23/03/2014, 04:21
... nature of the binding of ascorbic acid to proteins Although ascorbic acid is a small molecule, it blocks the most attractive binding subsites in the protein, leading to the inhibition of the enzyme ... Ascorbic acid binding Ascorbic acid (Fig 1A) inhibits the activity of HylP2 The structure of the complex of HylP2 with ascorbic acid shows that three molecules of ascorbic acid bind to HylP2 trimer ... observed in the side chains of Glu167 and Lys179 upon binding to ascorbic acid are shown by superimposing their binding regions of native structure (cyan) and that of complexed structure with ascorbic...
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The situation of increasing serum uric acid, related factors and efficacy of dietary intake in over 30 year of age subjects in rural area of thai binh province
Ngày tải lên :
21/10/2014, 20:53
... consumption of soft drinks which contain fructose would increase the level of serum uric acid, but in our study we did not find the impact of soft drink use to condition of serum uric acid levels Reducing ... rate of increase in serum uric acid was 9.2% (95% CI: 7.9 to 10.5%), in which increasing in serum uric acid was 6.5% in female and 12.0% in male - Serum uric acid levels increased with age in both ... 21.8% in female Author Miao performed study on 5,003 adult subjects in coastal areas of Shandong Province in China, the rate of increasing uric acid was 13.19%, in which the incidence in males...
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Characterization of the Carbon Stable Isotope Ratio and Fatty Acid Structure of Zostera japonica in Coastal Areas
Ngày tải lên :
05/09/2013, 10:17
... structure in Z japonica We found about 30 kinds of fatty acids in the leaves and stems and about 36 kinds of fatty acids in the roots and rhizomes of Z japonica We focused on the fatty acid content of ... Acid Methyl Esters Mix (47080-U, SUPELCO, USA); and kinds of long-chain fatty acids (LCFAs) These standards were used to obtain 56 kinds of fatty acids Therefore, the contents of each fatty acid ... KG Fig - Sampling sites for seagrasses Table Sampling conditions and cooperating institutions during sampling Table - Sampling conditions and cooperating institutions during sampling Site Z japonica...
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Tài liệu Báo cáo khoa học: Interruption of triacylglycerol synthesis in the endoplasmic reticulum is the initiating event for saturated fatty acid-induced lipotoxicity in liver cells pdf
Ngày tải lên :
14/02/2014, 22:20
... factor (ATF4) and of CCAAT ⁄ enhancer-binding protein homologous protein (CHOP) proteins downstream of eIF2a were observed (Fig 4A), indicating the initiation of ER stress-induced apoptosis Oleate ... cytokines, inhibition of insulin signaling, induction of endoplasmic reticulum (ER) stress, and promotion of cell death, mainly by apoptosis [6–12] On the other hand, unsaturated fatty acids ... forms of fatty acids exert remarkably different effects Exposure of a variety of cell types, including hepatocytes, to long-chain saturated fatty acids (SFAs) led to increased expression of proinflammatory...
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Tài liệu THE ROLES OF AMINO ACID CHELATES IN ANIMAL NUTRITION pdf
Ngày tải lên :
15/02/2014, 16:20
... Adenylate kinase Creatin kinase Arginine kinase 1,3-Diphosphoglycerate -> ADP-Transphosphatase Pyruvate kinase Hexokinase 6-Phosphofructokinase Galactokinase Phosphoglucokinase Gluconokinase Ribokinase ... nutrient including certain vitamins, amino acids and fats, any of which could decrease absorption; (c) any condition which increases the rate of passage of the minerals through the intestine, such ... result of increased bioavailability of these chelated forms v VI Introduction Of novel interest are the reports showing a protein sparing as a result of amino acid chelate supp1ementat ion In the...
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Tài liệu Báo cáo khoa học: Activation loop 3 and the 170 loop interact in the active conformation of coagulation factor VIIa pdf
Ngày tải lên :
18/02/2014, 08:20
... identied in an alanine scanning mutagenesis study of FVIIa, shedding light on the amino acid residues that are important for TF binding and or the cofactor effect [13] In terms of intramolecular ... as interesting as those involved in the TF-induced allostery Amino acid residues in FVIIa that are involved in the conformational balance that governs the equilibrium between zymogen-like and active ... strongly in favour of the former, can be identied by gain-ofactivity mutations Site-directed mutagenesis at certain positions in FVIIa has indeed resulted in molecules with increased intrinsic activity,...
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Tài liệu Báo cáo khoa học: Association of feather colour with constitutively active melanocortin 1 receptors in chicken docx
Ngày tải lên :
21/02/2014, 00:20
... into its active form, not by disrupting the internal constraint as proposed by the early rhodopsin studies and the ternary allosteric model, but by indirectly mimicking ligand-binding The amino ... is mainly expressed in the central regions of the brain, including the hypothalamus where it is an important regulator of food intake The MC4 receptor shares 60% of the amino acids with the MC1 ... [3H]cAMP and bovine adrenal binding protein and incubation for h at °C Standards containing nonlabeled cAMP were assayed in the same manner The incubates were then harvested by adding activated...
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Trends in dietary habits of the elderly: The Indonesian case pptx
Ngày tải lên :
05/03/2014, 21:20
... vitamin A and C were consumed in abundant amounts He found cases of anaemia in 39.1% of men and 35.3% of women.13 Conclusion and recommendation (1) The Indonesian elderly people are growing in ... circumstances in spite of wide variations in the way that care is provided in different societies Families play a critical role especially in developing countries, where the elderly population is increasing ... rapidly But in all societies families are typically generous in providing care In Indonesia the extended family system is still practised and the families regard the placing of the elderly in an ‘old...
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