diagnostic and prognostic value of procalcitonin in communityacquired pneumonia

... Systematic analysis of? ?the expression and? ?prognostic value of? ?ITPR1 and? ?correlation with tumor infiltrating immune cells in? ?breast cancer Bing Han1, Fang Zhen1, Xiu‑Shuang Zheng2, Jing Hu1*? ?and Xue‑Song Chen1*  ... of gene expression profiling data, a public database for cancer and normal gene expression profiling, filling the gap in cancer genomics big data information Including 9736 tumors from TCGA and ... dissociated, and then Beclin1 formed a complex with ITPR1 activating and promoting the production of autophagy [18–20] ITPR1 participated in autophagy induced by NK cells and reduced the killing effect of

Ngày tải lên: 04/03/2023, 09:33

... distributed in the chest, abdomen, and back These findings are in line with those reported in the literature, and suggest that the staging of lung cancer should include a thorough examination of soft ... assessed the incidence and imaging characteristics of STM from lung cancer using 18 F-FDG PET/CT, which will help clinical and nuclear medicine doctors deepen their understanding of the disease and guide ... ARTICLE Open Access Imaging features and prognostic value of 18 F-FDG PET/CT detection of soft-tissue metastasis from lung cancer: a retrospective study Tingting Xu1,2†, Xinyi Zhang1,2†, Shumao

Ngày tải lên: 03/07/2020, 02:55

... evaluated the diagnostic value of PCT and CRP in a group of 59 patients undergoing CPB. At a cut- off level of 4 ng/ml, PCT had a sensitivity of 86% and a specif- icity of 98% in predicting infection, ... procedures, and to investi- gate the value of PCT levels in terms of diagnosing infection or predicting outcome in these patients. Materials and methods We performed a search on MEDLINE using the ... characterising the role of PCT as a tool in discriminating infection, identifying the relation between PCT, organ failure, and severity of sepsis syndromes, and assessing the possible role of PCT in

Ngày tải lên: 13/08/2014, 03:20

... These findings were corroborated by two independent studies [19,31] (Table 1) We recently confirmed the prognostic value of brainstem lesions in the upper pons and lower midbrain in a study of 73 ... have potential in terms of predicting outcome Following a brief description of the sequences used, this review focuses on the prognostic value of MRI in patients with traumatic brain injury, anoxic/hypoxic ... spectroscopy profile of the pons after traumatic brain injury (a) Normal profile The peak of N-acetyl-aspartate (NAA) is higher than the peaks of choline (Cho) and creatine (Cr) (b) Neuronal loss profile

Ngày tải lên: 13/08/2014, 08:20

... this study investigated the role of UA in TBI in both clinical patients and experimental animals Methods: In TBI patients, serum UA concentrations were measured within days after injury Clinical ... leading cause of gout; however, recent studies have validated its neuroprotective role in ischemic stroke Because the potential protective effects of UA in traumatic brain injury (TBI) remain ... Rui Xu, Weina Chai, Gang Huo, Xiaochuan Sun and Chongjie Cheng Department of Neurosurgery, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China  Corresponding author:

Ngày tải lên: 14/01/2020, 21:22

... of CKs and SALL4 as prognostic factors in HCC and ICC To evaluate the prognostic value of CKs and SALL4 in HCC and ICC, we examined the correlation between the expression of CK7/19, CK8/18, and ... Value of Cytokeratin and Sal-Like Protein Expression in Hepatocellular Carcinoma and Intra-Hepatic Cholangiocarcinoma in Taiwan Yih-Shyong Lai 1, Chiung-Chi Cheng 1,2, Ming-Tsung Lee 3, Wei-Ting ... plectin, a versatile cytoskeleton cross-linking protein in a variety of tissues and cells, was deficient in human HCC [7] We recently reported that by affecting the expression and organization of

Ngày tải lên: 15/01/2020, 02:18

... work Department of Clinical Laboratory Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing 210002, China Department of Clinical Laboratory Medicine, Nanjing Drum Tower Hospital, ... studies included in meta-analysis regarding OS (c) and TTP (d) The 95% confidence intervals of the regression line’s y intercept include zero, P values were 0.59 and 0.89, respectively, indicating ... (81601765, 81572074) and Jiangsu Province Postdoctoral Science Foundation (1601155B), including the design of the study and collection, analysis, and interpretation of data and in writing the manuscript

Ngày tải lên: 30/05/2020, 21:52

... University, Changsha, Hunan, China Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Key Laboratory of Carcinogenesis, Ministry of Health, Cancer Research Institute, Xiangya Hospital, ... breast cancer in developing countries has been increasing in recent years In China, breast cancer has become the most common cancer in females and the leading cause of cancer-related death in younger ... these upregulated proteins were involved in binding activities, such as RNA binding and ion binding (Additional file 1: Figure S1C) The 240 proteins that were downregulated in lymph node metastases

Ngày tải lên: 17/06/2020, 17:25

... (IHC) staining of HER2 and HER3 expression in gastric cancer HER2 negative staining (a), HER2 weak staining (b), HER2 moderate staining (c) and HER2 strong staining (d) HER3 negative staining (e), ... results of IHC was performed in Fig and Fig Evaluation of immunohistochemistry HER2 and HER3 levels were scored as follows: 0, no staining or in 10% of tumor cells Moderate staining (2+) and strong ... grading system based on both the proportion of stained cells and staining intensity [18] Staining intensity was scored as (negative), (weak), (moderate), or (strong), and the percentage of positive

Ngày tải lên: 06/08/2020, 03:41

... adenocarcinoma and other cancers Serum ALT and AST are the circulating transaminases in the body, and are specific markers of liver dysfunction, which can generate products in gluconeogenesis and amino ... Our purpose was to investigate the prognostic value of the preoperative alanine aminotransferase/aspartate aminotransferase (ALT/AST) ratio and gamma glutamyltransferase (GGT) in ESCC patients ... levels of LSR and decreased levels of GGT might predict shorter overall survival in ESCC patients Our findings suggest that serum LSR and GGT levels could be used as a key predictor of survival in

Ngày tải lên: 06/08/2020, 06:42

... Access Prognostic value of S1PR1 and its correlation with immune infiltrates in breast and lung cancers Limei Zhong1, Linling Xie2, Zhiyong Yang1, Lijuan Li1, Shaohua Song1, Donglin Cao1* and Yufeng ... angiogenesis and tumor growth [13] Studies have shown that S1PR1 inhibits VEGF signaling by promoting the interaction between VE-cadherin and VEGFR2, thereby inhibiting VEGF-induced vascular sprouting ... an important role in recruiting and governing immune infiltration in BRCA, LUAD and LUSC To further elucidate the molecular mechanisms underlying the role of S1PR1 in breast and lung cancers,

Ngày tải lên: 19/09/2020, 22:14

... study, we investigated relationship between elevated levels of three biomarkers of CEA, CYFRA21-1 and NSE (individually and in combination) and metastasis, survival status and prognosis in lung ... combination of three biomarkers The cutoff values of three biomarkers for groupings were developed on the training group (N = 432) and verified in a validation group (N = 436) Clinical and laboratory ... selected training group (N = 432), reserving the left 436 cases for validation The cutoff values of three biomarkers for groupings were developed on the training group and tested in a validation

Ngày tải lên: 20/09/2020, 01:15

... carcinoma of urinary bladder The staining patterns and prevalence rate of Her2/neu protein profile and amplification status of Her2/neu gene respectively, are illustrated in Fig The expression of ... consisting of baking for 30 min, deparaffinization with EZ Prep (Ventana) at 75 °C, cell conditioning (CC2; Ventana) using “Mild CC2 cycle min, standard CC2 cycle 12 min, extended cycle min” followed ... staining with fast red and naphthol phosphate for Finally, the slides were counterstained with Hematoxylin II for and with Bluing Reagent for At the completion of the run, stained slides having

Ngày tải lên: 20/09/2020, 17:45

... studies, our findings suggest that the patterns of expression of PN in both compartments can allow for the development of IHC “signatures” that maintain a strong independent predictive value of both ... expression and clinicalpathological features, tumour phenotype and the risk of mortality following surgery were analysed Appropriate statistics, including the Fine and Gray competing risk proportional ... time of surgery and cryopreserved up to processing We aimed to evaluate the prognostic value of serum levels of PN as well The results of this second part of the project form the object of a

Ngày tải lên: 21/09/2020, 11:39

... cut-off value is from ROC curve analysis The determination of ROC cut-off value is always complied with the principle of maximization in the sensitivity plus (1-specificity) or the maximization of ... (LFFR) and disease-free survival (DFS) was outweighed by the volume of under-dosing due to neighboring neurological structures In their analysis of 444 patients in whom dose tolerances were maintained ... ARTICLE Open Access Prognostic value of the distance between the primary tumor and brainstem in the patients with locally advanced nasopharyngeal carcinoma Yuxiang He1, Ying Wang1, Lin Shen1, Yajie

Ngày tải lên: 21/09/2020, 11:42

... positive BX staining was most often found for maspin and PTEN, in with approximately two thirds of the samples were positively stained Staining of P53 and BMI1 was less common, with 19 % and 26 % positive ... % of the tumor cells were stained with high intensity In addition, changes of biomarkers following chemotherapy were investigated by comparing the immunohistochemical grades of BXs and RXs of ... death by chemotherapeutic drugs through induction of maspin [29] and, on the other hand, studies demonstrated increased expression of maspin to be an indicator of poor survival [46] or poor chemotherapy

Ngày tải lên: 30/09/2020, 10:54

... roles in the proper control of Smad access to activating receptors involved in regulation of TGF-β signaling [17-19] Interestingly, ELF is a key suppressor of tumorigenesis [20,21] Disruption of ... result in miscolocalization of Smad3 and Smad4, and disruption of TGF-β signaling [22] About half of mice with heterozygous deletion of ELF developed hepatocellular carcinoma, and 90% of ELF+/−/Smad4+/− ... profound tumor suppressor by prohibiting cell cycle progression and arresting cells in early G1 phase However, misregulation of TGF-β signaling promotes tumor growth and invasion, evasion of

Ngày tải lên: 30/09/2020, 13:01

... unclear [24] The aim of the present study was to examine the prognostic value of different assessments of LVI and BVI in patients with early, and in particular node-negative and triple-negative ... Examples of LVI and BVI in invasive breast cancer sections stained with H&E, D2-40 and Factor VIII A: H&E conspicuous carcinoma emboli in large and small vascular spaces (single arrows) accompanying ... sections stained with H&E (I) showing tumour cells inside endothelial lining space, however, D2-40 (J) and Factor VIII (K) are both negative suggesting stromal artifact (note positive staining of blood

Ngày tải lên: 14/10/2020, 15:42

... capital profitability is declining. The internalization of information within the same institution may thus enhance intra-circuit and inter-circuit stability by reducing the incentive to overfinancing. The ... placing money with investment financial institutions in the capital market, and hold the remaining share in non- interest bearing, short-term bank deposits (eq. 7). The share of savings going ... leading to overfinancing of capital good production. Figure 1 shows financial investors rationing investing companies at the point of maximum risk-adjusted gross rate of return, * − L r , and...

Ngày tải lên: 24/10/2012, 09:33