... conformations: one pointing towards the phosphate group ofthe ligand andthe other pointingout into solution. Inthe TcRpiB-wt (i.e. ligand-free)structure, Arg113 is only inthe latter conformation(Fig. ... four major stages inthe bio-logical cycle ofthe parasite (i.e. the epimastigote and the metacyclic trypomastigote inthe insect vector, and the intracellular amastigote andthe bloodstream trypo-mastigote ... of Gly70. O1 of 4PEH interacts with the backbone nitrogen of Ser71 as seen for the O2interaction in R5P. As for O1 of R5P, the terminalgroup ofthe inhibitor has hydrogen bonds to Asn103¢and...
... discovery of a brain-specific MT isoform, GIF, in 1991, sparked considerable interest in understanding the role of all MTs inthe brain, and particularlywithin the injured or diseased brain. Inthe ... suggesting that this MT isoform has different and distinct functions within the brain. Furthermore, the discovery and continued investigation of this brain-spe-cific MT isoform has led to intense interest ... the brain. Further studies are required todetermine the function of GIF within the normal,injured and neurodegenerative brain, and to establish the therapeutic potential ofthe protein.AcknowledgementsThis...
... buying inflows to reduce the NOFP. Nonetheless, in certain cases involving large one-off inflows of FDI, the SARB may have sufficient prior information to make an assessment as to whether the ... done either by forcing a step exchange rate depreciation (and thereby generating the expectation of a strengthening ofthe rand) or by raising interest rates. Under either of these options, it ... much, and what type ofcapital inflow to buy. Specifically, how can the central bank make use of prior knowledge relating to the volatility and persistence of capital flows? And how would the interaction...
... (2000) apply the model of Ho and Saunders(1981) to analyze the determinants of interest margins in six countries ofthe European Union andthe US during the period 1988–95. They find that macroeconomic ... margins and profits compared to domestic banks in developing countries, while the opposite holds in developed countries. Gelos (2006) studies thedeterminantsof bank interest margins in Latin ... Journal of Banking and Finance 16, 1173-1178. Saunders, A. and L. Schumacher (2000). TheDeterminantsof Bank Interest Rate Margins: An International Study,” Journal of International Money and...
... regarding the demand for informationMeeting information demand has become easier on one hand, but has also become more complicated and difficult on the other. Because ofthe emergence of information ... for the dynamic nature ofthe Internet andthe information that can be found on it;3. The search for information is often limited to a few Internet services, such as the WWW. Finding information ... can offer.4.3.1 Middle layer (agent) functions" ;The fall inthe cost of gathering and transmitting information will boost productivity inthe economy as a whole, pushing wages up and...
... against Cirrhosis), is a multicenter study ofthe potential benefit of prolonged peginterferon therapy in mitigating the progression of fibrotic liver disease. [8] In this study, 391 of the ... dose discontinuation in 3/20 (15%). Forns and colleagues used relatively high-dose interferon/ribavirin therapy in their cohort of 30 patients awaiting transplantation in Spain in an effort ... factors, specifically G-CSF and erythropoietin, has allowed more aggressive dosing of interferon and ribavirin. [13, 14] Finally, growing experience with antiviral therapy in this high-risk group...
... rather prefer to use the image of dragon inthe writing: He called Đồng Văn and Mèo Vạc the head ofthe dragon”; Cà Mau the tail ofthe Vietnamese dragon”; Thăng Long the “soaring dragon” and ... non-lexicalization ofthe concepts, the lack of super ordinates of hyponyms etc. The main contribution of this paper is to draw out the main ways of dealing with the hurdles by investigating how an ... but the nominal sense ofthe words is noting to the end of the book.Stepping into the land of one to part of one equivalence, which happens when a English expression could only covers part of...
... point of view, character and setting. Technique has to do with the structuring ofthe story into the plot so that the writer can convey the theme andthe manipulating ofthe language in order ... Throughout the story, we do not see any of her involvements into any conversations with the grandmother. Regarding the children, they disapproved ofthe decision of their grandmother but, as the youngest ... improve their critical thinking of their own ways of life, their belief, their religion, which means their culture andthe world in which ” they live in, which is the society . Inthe same...
... for use in training and testing the neural network. A large training data reduces the risk of under-sampling the nonlinear function, but increases the training time. To improve training, preprocessing ... reliance ofthe ANN631between the predicted value andthe measured value. The properties ofthe soil used for training ofthe MANN models are shown in Table 1. Table 1. Properties ofthe ... generated and, the effect on the determination of Coefficient of consolidation will be pronounced. On the other hand, if pore pressures become excessive, assumptions made in deriving the theory...
... 64Intelligent Software Agents on the Internet 2Preamble5. Search engines are domain-independent in the way they treat gathered information andinthe way they enable users to search in ... accounted for inthe future, that arenot using the WWW andthe Internetright now:"Many information-intensive consumers in the US population are in the other-half populationrather than the upstreampopulation. ... agent, called the Info Agent,is used as the interface between the system andthe user. The Info Agent, in its turn, uses a so called Interface Agentfor handling the communication with the user....
... FrameworkConclusions, including the results of the November 2001 Workshop Management Framework - Introduced Marine PestsManagement capabilities and approaches APEC andthe MRCWG have a role in liaising ... PestsBackgroundWithin APEC little is known on the introduction of marine pestsLittle practical information on measures to prevent introductionsLack of knowledge in what individual countries are doingNeed ... NACA to enhance the effectiveness of existing instruments within APEC Institutional arrangements for managing the marine environment is fragmented in most economies Baseline surveys to...