... conformations: one pointing towards the phosphate group of the ligand and the other pointing out into solution. In the TcRpiB-wt (i.e. ligand-free) structure, Arg113 is only in the latter conformation (Fig. ... four major stages in the bio- logical cycle of the parasite (i.e. the epimastigote and the metacyclic trypomastigote in the insect vector, and the intracellular amastigote and the bloodstream trypo- mastigote ... of Gly70. O1 of 4PEH interacts with the backbone nitrogen of Ser71 as seen for the O2 interaction in R5P. As for O1 of R5P, the terminal group of the inhibitor has hydrogen bonds to Asn103¢ and...
Ngày tải lên: 15/03/2014, 00:20
... discovery of a brain-specific MT isoform, GIF, in 1991, sparked considerable interest in understanding the role of all MTs in the brain, and particularly within the injured or diseased brain. In the ... suggesting that this MT isoform has different and distinct functions within the brain. Furthermore, the discovery and continued investigation of this brain-spe- cific MT isoform has led to intense interest ... the brain. Further studies are required to determine the function of GIF within the normal, injured and neurodegenerative brain, and to establish the therapeutic potential of the protein. Acknowledgements This...
Ngày tải lên: 16/02/2014, 15:20
báo cáo hóa học:" Review of the temporal and geographical distribution of measles virus genotypes in the prevaccine and postvaccine eras" potx
Ngày tải lên: 20/06/2014, 04:20
The Volatility of Capital Flows in South Africa: Some Empirical Observations
... buying inflows to reduce the NOFP. Nonetheless, in certain cases involving large one-off inflows of FDI, the SARB may have sufficient prior information to make an assessment as to whether the ... done either by forcing a step exchange rate depreciation (and thereby generating the expectation of a strengthening of the rand) or by raising interest rates. Under either of these options, it ... much, and what type of capital inflow to buy. Specifically, how can the central bank make use of prior knowledge relating to the volatility and persistence of capital flows? And how would the interaction...
Ngày tải lên: 24/10/2012, 09:11
The Determinants of Commercial Bank Profitability in Sub-Saharan Africa potx
... (2000) apply the model of Ho and Saunders(1981) to analyze the determinants of interest margins in six countries of the European Union and the US during the period 1988–95. They find that macroeconomic ... margins and profits compared to domestic banks in developing countries, while the opposite holds in developed countries. Gelos (2006) studies the determinants of bank interest margins in Latin ... Journal of Banking and Finance 16, 1173-1178. Saunders, A. and L. Schumacher (2000). The Determinants of Bank Interest Rate Margins: An International Study,” Journal of International Money and...
Ngày tải lên: 06/03/2014, 14:20
Working Paper Series no 1096 / September 2009: The determinants of Bank capital structure potx
Ngày tải lên: 15/03/2014, 10:20
Báo cáo khoa học: Structural determinants of protein stabilization by solutes The importance of the hairpin loop in rubredoxins pdf
Ngày tải lên: 30/03/2014, 15:20
báo cáo sinh học:" Managerial competencies of hospital managers in South Africa: a survey of managers in the public and private sectors" docx
Ngày tải lên: 18/06/2014, 17:20
Intelligent Software Agents on the Internet: an inventory of currently offered functionality in the information society & a prediction of (near-)future developments
... regarding the demand for information Meeting information demand has become easier on one hand, but has also become more complicated and difficult on the other. Because of the emergence of information ... for the dynamic nature of the Internet and the information that can be found on it; 3 . The search for information is often limited to a few Internet services, such as the WWW. Finding information ... can offer. 4.3.1 Middle layer (agent) functions " ;The fall in the cost of gathering and transmitting information will boost productivity in the economy as a whole, pushing wages up and...
Ngày tải lên: 08/10/2012, 15:22
Báo cáo y học: "Antiviral therapy of HCV in the cirrhotic and transplant candidate"
... against Cirrhosis), is a multicenter study of the potential benefit of prolonged peginterferon therapy in mitigating the progression of fibrotic liver disease. [8] In this study, 391 of the ... dose discontinuation in 3/20 (15%). Forns and colleagues used relatively high-dose interferon/ribavirin therapy in their cohort of 30 patients awaiting transplantation in Spain in an effort ... factors, specifically G-CSF and erythropoietin, has allowed more aggressive dosing of interferon and ribavirin. [13, 14] Finally, growing experience with antiviral therapy in this high-risk group...
Ngày tải lên: 31/10/2012, 17:11
Equivalence in the translation of vietnamese cultural words in the book “wandering through vietnamese culture” by huu ngoc
... rather prefer to use the image of dragon in the writing: He called Đồng Văn and Mèo Vạc the head of the dragon”; Cà Mau the tail of the Vietnamese dragon”; Thăng Long the “soaring dragon” and ... non-lexicalization of the concepts, the lack of super ordinates of hyponyms etc. The main contribution of this paper is to draw out the main ways of dealing with the hurdles by investigating how an ... but the nominal sense of the words is noting to the end of the book. Stepping into the land of one to part of one equivalence, which happens when a English expression could only covers part of...
Ngày tải lên: 07/11/2012, 14:31
Some aspects of American culture and society in the twentieth and twenty-first centuries through a number of selected short literary works
... point of view, character and setting. Technique has to do with the structuring of the story into the plot so that the writer can convey the theme and the manipulating of the language in order ... Throughout the story, we do not see any of her involvements into any conversations with the grandmother. Regarding the children, they disapproved of the decision of their grandmother but, as the youngest ... improve their critical thinking of their own ways of life, their belief, their religion, which means their culture and the world in which ” they live in, which is the society . In the same...
Ngày tải lên: 07/11/2012, 15:01
Estimation of Proper Strain Rate in the CRSC Test Using a Artificial Neural Networks
... for use in training and testing the neural network. A large training data reduces the risk of under-sampling the nonlinear function, but increases the training time. To improve training, preprocessing ... reliance of the ANN 631 between the predicted value and the measured value. The properties of the soil used for training of the MANN models are shown in Table 1. Table 1. Properties of the ... generated and, the effect on the determination of Coefficient of consolidation will be pronounced. On the other hand, if pore pressures become excessive, assumptions made in deriving the theory...
Ngày tải lên: 22/03/2013, 15:01
A study of kinematic vertical motions in the troposphere in Iraq
Ngày tải lên: 05/09/2013, 17:03
A study on oral presentation difficulties of second year english majors of phuong dong university in the speaking lessons and solutions
Ngày tải lên: 07/09/2013, 13:02
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