describe the 3 methods of heat transfer u2013 convection conduction and radiation
Báo cáo y học: "Gene Therapy: The Potential Applicability of Gene Transfer Technology to the Human Germline"
... 66(1):167-167. 38 . Smith KR. The role of sperm-mediated gene transfer in genome mutation and evolution. Med Hypotheses 2002; 59(4): 433 - 437 . 39 . Zani M, Lavitrano M, French D, Lulli V. The mechanism of ... contributed to the embryo, the resultant offspring will be chimeric (up to ca. 50% of animals). The ESC contribution to a mouse can high (up to ca. 80% of the cells), and will often include the germline ... prospects for gene therapy. Gene Ther. 2002; 9(11):7 13- 718. 85. Lipps HJ, Jenke ACW, Nehlsen K, et al. Chromosome-based vectors for gene therapy. Gene Ther. 20 03; 30 4: 23- 33. 86. Abbondanzo...
Ngày tải lên: 03/11/2012, 10:01
An experimental investigation of heat transfer and fluid flow in a rectangular duct with inclined discrete ribs
... Saini J.S. and Solanki S.C. Heat transfer and friction in solar air heater duct with V-shaped rib roughness on absorber plate. Int. Journal of Heat and Mass Transfer 2002; 45: 33 83- 33 96. [19] ... S.J. The effect of gap position in discrete ribs on local heat/ mass transfer in a square duct Journal of Enhanced heat transfer 20 03; 10 (3) : 287 -30 0. [ 13] Gupta D. Solanki S.C and Saini J.S. Thermo-hydraulic ... value of turbulent intensity is observed at the relative gap width of 1.0 which is in the line of heat transfer measurements. These results of PIV showed good agreement between the heat transfer...
Ngày tải lên: 05/09/2013, 16:10
Tài liệu Báo cáo khoa học: Nucleolin/C23 mediates the antiapoptotic effect of heat shock protein 70 during oxidative stress pptx
... increase) Caspase -3 activity (fold increase) 50 30 20 10 0 3 4 2.5 3. 5 3. 5 3 2.5 2 1.5 1 0.5 0 0.5 mmol·L –1 H 2 O 2 2 1.5 1 0.5 0 Ctrl Ctrl pcDNA3.1 pcDNA3.1-C 23 pcDNA3.1-Hsp70 pcDNA3.1-C 23 + pcDNA3.1-Hsp70 pcDNA3.1 ... lost. Taken together, our results demonstrate an impor- tant relationship among the regulation of nucleo- lin ⁄ C 23, the activation of caspase -3 and the induction of apoptosis under the setting of oxidative ... minimize the number of animals used and their suffering. H 2 O 2 pcDNA3.1 100 10 0 0.5 Time (h) 1 23 Bcl-2 mRNA/GAPDH mRNA (%) pcDNA3.1 pcDNA3.1-C 23 Bcl-2 GAPDH A B Fig. 5. Effect of nucleolin ⁄ C23...
Ngày tải lên: 16/02/2014, 09:20
Tài liệu Báo cáo khoa học: Template requirements and binding of hepatitis C virus NS5B polymerase during in vitro RNA synthesis from the 3¢-end of virus minus-strand RNA docx
... new mutants of the 3 -end of minus-strand RNA. Results Effect of mutations in the 3 - or the 5Â-end of the ()IRES HCV RNA template on RNA synthesis The secondary structure of the 3 -terminal ... structure of the SL-A1 and of the SL-B1 hairpin and the 4 nt at the 3 -end remained free as in the wild-type ()IRES. RNA synthesis obtained with the (–)IRES 104 RNA was only 24% of that of the wild-type ... RNA synthesis by recombinant HCV NS5B using deletion mutants of the 3 terminus of the minus-strand RNA but deletions were made on the basis of the structure of the 5ÂUTR of the plus-RNA, the structure...
Ngày tải lên: 20/02/2014, 01:20
Báo cáo khoa học: The propeptide in the precursor form of carboxypeptidase Y ensures cooperative unfolding and the carbohydrate moiety exerts a protective effect against heat and pressure pot
... transition for heating and high pressure. Fig. 3. Pressure-induced changes of the centre of the spectral mass of (A) proCPY (d)andDgly proCPY (s)at25°C(B)CPY(d )and Dgly CPY (s)at25°C, and (C) CPY ... that the cleft of the active site will be located in the interface between the two structural domains of CPY and would be filled by the propeptide, thus uniting the two domains in a body, as if the ... that the thermal unfolding process of the precursor form follows a two-state transition. The ratio of the unfolding enthalpy (DH cal )tothe van’t Hoff enthalpy (DH v ) was 1.05 (DH cal and DH v values were...
Ngày tải lên: 07/03/2014, 21:20
Báo cáo khoa học: The 3¢-UTR of the mRNA coding for the major protein kinase C substrate MARCKS contains a novel CU-rich element interacting with the mRNA stabilizing factors HuD and HuR ppt
... detection of proteins crosslinked Fig. 2. Formation of two major complexes between Swiss 3T3 proteins and the 3 -UTR of the MARCKS mRNA. (A) The MARCKS 3 -UTR, the stop codon UAA of the coding ... (CDS) and MARCKS 3 -UTR were driven by a CMV-promoter and used for transfection of Swiss 3T3 bro- blasts. Length of the MARCKS 3 -UTR sequences [38 ] of pDK1: 131 02597 bp (complete 3 -UTR of MARCKS); ... 2002) Eur. J. Biochem. 270, 35 0 36 5 (20 03) Ó FEBS 20 03 doi:10.1046/j.1 432 -1 033 .20 03. 033 96.x NP-40, 10 m M NaCl, 3 m M MgCl 2 and 10 m M Tris/HCl pH 7.4) prior resuspending the nuclear pellet in glycerol storage...
Ngày tải lên: 08/03/2014, 08:20
Báo cáo khoa học: The 3-ureidopropionase of Caenorhabditis elegans, an enzyme involved in pyrimidine degradation pptx
... Homology model of the subunit of 3- ureido- propionase, based upon the crystal structure of the D. melanogaster 3- ureidopropionase (Protein Data Bank code: 2VHH). Fig. S3. To determine whether 3- ureidopropionase deficiency ... dithiothreitol at )80 °C. The purity of the recombinat protein was ‡ 85% as judged by SDS ⁄ PAGE. Molecular size of the 3- ureidopropionase The molecular size and oligomeric state of the 3- ureidopro- pionase ... fusion protein under the control of the 3- ureidopropionase promoter. Results and Discussion Cloning and expression of recombinant 3- ureidopropionase The sole homolog of 3- ureidopropionase in...
Ngày tải lên: 23/03/2014, 03:20
molecular dynamics simulation of heat transfer and phase change during
Ngày tải lên: 06/05/2014, 08:55
molecular dynamics simulation of heat transfer and phase change during
Ngày tải lên: 06/05/2014, 08:57
molecular dynamics simulation of heat transfer and phase change during
Ngày tải lên: 06/05/2014, 08:59
Tài liệu Báo cáo khoa học: Roles of heat shock factors in gametogenesis and development pptx
... increased production of reactive oxygen species [27 ,34 ]. In line with findings in the heart and kidney [35 ,36 ], and together with the down-regulation of many HSPs in oocytes [33 ], the deficiency in ... associated with reduced methylation of the histone H3K9, irre- spective of the relative location of the HSF4-binding regions and of the transcriptional status of genes located around the HSF4-binding regions. ... Nature 30 5, 33 1 33 3. 40 Christians E, Campion E, Thompson EM & Renard JP (1995) Expression of the HSP 70.1 gene, a landmark of early zygotic activity in the mouse embryo, is restricted to the...
Ngày tải lên: 18/02/2014, 04:20
Tài liệu Báo cáo khoa học: "The Effect of Corpus Size in Combining Supervised and Unsupervised Training for Disambiguation" pdf
... 73. 4% 73. 0% 51.4% 50% 119 53 82.8% 73. 6% 73. 6% 73. 2% 51.7% 25% 11950 81.5% 73. 6% 73. 7% 73. 3% 51.7% 5% 11 737 77.4% 74.1% 74.2% 73. 7% 52 .3% 1% 118 03 72.9% 73. 6% 73. 6% 73. 2% 51.6% 0.05% 8486 58.0% 73. 9% ... agreement between the verb and only one of the NPs, attach to this NP. 3. If one of the NPs is in a list of person entities, attach to the other NP. 4 4. If possible, use LBD. 5. If none of the above ... with a number of values (2, 3, and 4) on the development set. Accuracy of the algo- rithm was best for a value of 3. The results presented here differ slightly from those in (Atterer and Schăutze, 2006)...
Ngày tải lên: 20/02/2014, 12:20
Tài liệu From Burden to “Best Buys”: Reducing the Economic Impact of Non-Communicable Diseases in Low- and Middle-Income Countries pdf
... the growing burden of NCDs: ã A global analysis of the economic impact of NCDs by the World Economic Forum and the Harvard School of Public Health ã An analysis of the costs of scaling up a core ... result of its use. The designations employed and the presentation of the material in this overview do not imply the expression of any opinion whatsoever on the part of the World Health Organization ... reports, one led by the World Economic Forum and the Harvard School of Public Health, and the other developed by the World Health Organization: The Global Economic Burden of Non-communicable...
Ngày tải lên: 20/02/2014, 19:20
Occupational therapy interventions and physical activity interventions to promote the mental wellbeing of older people in primary care and residential care pdf
... knowledge of (and application of) the principles and methods of occupational therapy and health and wellbeing promotion − effective communication skills to engage with older people and their ... participants and use it to inform the content of the sessions and to gauge levels of motivation. 7 Appendix B Summary of the methods used to develop this guidance Introduction The report of the ... does the effectiveness of interventions depend on the characteristics of those delivering the intervention, the involvement of older people in their design and delivery or the involvement of...
Ngày tải lên: 05/03/2014, 18:20
Báo cáo khoa học: The influence of cold shock proteins on transcription and translation studied in cell-free model systems pdf
... mm tyrosine, 0 .3 mm of each of the other 19 amino acids, 33 lgặmL )1 of the respective plasmid DNA, 140 lgặmL )1 T7 RNA polym- erase, 35 .1% (v ⁄ v) S30 extract in volume of 26 lL and 4 lL water ... maritima 35 3 139 .5 230 0.59 0.02 e 8.0 f B. caldolyticus 33 3 215.0 420 2 .33 – g – g B. subtilis 30 8 451.8 800 4.51 0 .37 h – g a In vitro transcription-translation assay was performed at 31 0 K. b Optimal ... (Table 1). Note that the values obtained do not critically depend on the other free parameters of the model, a property of the used function. On the other hand, this means that the other parameters...
Ngày tải lên: 07/03/2014, 21:20
Báo cáo khoa học: Homoadenosylcobalamins as probes for exploring the active sites of coenzyme B12-dependent diol dehydratase and ethanolamine ammonia-lyase docx
... Research from the Ministry of Education, Culture, Sports, Science and Technology, Japan, and from the Japan Society for Promotion of Science ( 131 25205 and 134 80195 to TT) and by the Austrian Science ... upon binding to the enzyme in the pres- ence of ethanolamine, although they showed red or blue shift of the a-band by less than 6 nm (Fig. 3J–L). The steady-state concentrations of cob(II)alamin ... between the enzyme and coenzyme at both the cobalamin moiety and the adenine ring of the adenosyl group seem to produce angular strains and tensile force that likely contribute to labilization of the...
Ngày tải lên: 07/03/2014, 21:20
Báo cáo khoa học: Structure of the substrate complex of thymidine kinase from Ureaplasma urealyticum and investigations of possible drug targets for the enzyme pdf
... Synthesis of 5-(carbo- ranylalkylmercapto)-2Â-deoxyuridines and 3- (carbo- ranylalkyl) thymidines and their evaluation as substrates for human thymidine kinases 1 and 2. J Med Chem 42, 33 78 33 89. 23 ... method at 14 °C. The protein solution consisted of 10 mgặmL )1 Uu-TK, 5 mm Thd and 3 mm AMP-PCP, whereas the reservoir solution consisted of 15% poly(ethylene glycol) 33 50 and 0 .3 m ammonium for- mate. ... Here the structure with the substrate deoxythymidine is presented. The substrate binds similarly to the deoxythymidine part of the feedback inhibitor, and the lasso-like loop binds the base and...
Ngày tải lên: 30/03/2014, 11:20