... and uptake of ions, enzymatic and nonenzymatic antioxidant response, maintenance of redox and energetic status, salt inclusion/excretion and genetic control (Flowers and Colmer 2008) Understanding ... upregulation of the antioxidant enzymes and an even higher relative contribution of GR1 and of Cu/Zn-SOD The authors explain these results with less ROS generation and a better maintenance of redox ... stresses and extend genetic resource and manipulate stress tolerance mechanisms Halophytes are also an important plant species with potential for the purposes of desalination and restoration of saline...
Ngày tải lên: 14/03/2014, 10:20
... figures were performed with the aid of software (Origin Version 7.5 and SPSS Version 13.0) Results Expression of b1- and b2-adrenergic receptors in SGC7901 and BGC-823 cells Because propranolol ... antagonist, the expression of b1- and b2-ARs was determined at both the mRNA and protein level in SGC-7901 and BGC-823 cells by RT-PCR and western blot Our results showed that b1- and b2-adrenergic receptors ... http://www.ro-journal.com/content/5/1/98 Page of Figure Expression of b-ARs in human gastric cell lines SGC-7901 and BGC-823 by RT-PCR and western blotting (A) Expression of bARs in human gastric cell lines SGC-7901 and BGC-823...
Ngày tải lên: 09/08/2014, 09:20
Báo cáo y học: "A general framework for quantifying the effects of DNA repair inhibitors on radiation sensitivity as a function of dose" pptx
... the presence and absence of chemical inhibitors of PARP activity The variable nature and magnitude of the effects of PARP inhibition on clonogenic survival among these cell lines offered a useful ... comparison of the parameters in the treated and untreated experiments As a consequence, quantitative assessment of the effect of modifiers of DNA repair upon four distinct components of the radiation ... populations of T98G By contrast, analysis of figures 2b, 3a and 3b indicated that PJ34 did not affect low-dose radiation sensitivity of confluent populations of T98G glioma cells, or of U373MG...
Ngày tải lên: 13/08/2014, 16:21
báo cáo khoa học: " UV-B-induced signaling events leading to enhanced-production of catharanthine in Catharanthus roseus cell suspension cultures" pps
... alkalinization of the culture medium, generation of hydrogen peroxide, activation of CDPK and MBPK as well as accumulation of catharanthine and stimulation of transcription of Tdc and Str genes ... UV-B-induced stimulation of MBPK and CDPK activities and the UV-Binduced accumulation of Tdc and Str mRNAs, and catharanthine Because EGTA and verapamil are unlikely to enter cells, and verapamil blocks ... phosphorylation of H IIIS (a) and MBP (b) under standard conditions as described in materials and methods A second set of cells was similarly treated and the total RNA was isolated at the indicated times and...
Ngày tải lên: 12/08/2014, 05:20
DETOXIFICATION OF TRICHLOROETHYLENE (TCE) USING SOLAR LIGHT/TiO2 IN A UV CONCENTRATING RADIATION SYSTEM
... were confirmed by comparison of mass spectra and retention time with the library standards The production of methyl esters form DCAA, and TCAA looks to be from the use of methanol solvent for dissolving ... Turchi C and Link H (1993) Operation of a solar photocatalytic water: Treatment system at a superfund site Photocatalytic Purification and Treatment of Water and Air, Edited by D F Otlis and H Al-Ekabi, ... 10:00(a.m) to 4:00(p.m) Figure The effect of control conditions (solar light only and TiO2 only), and photocatalytic condition on the degradation of TCE and chloride production (as HCl) (Experimental...
Ngày tải lên: 05/09/2013, 08:40
Tài liệu Báo cáo Y học: The effects of ring-size analogs of the antimicrobial peptide gramicidin S on phospholipid bilayer model membranes and on the growth of Acholeplasma laidlawii B ppt
... excitation and emission of nm and quartz cells of 1-cm path length; the excitation and emission were recorded at wavelengths of 496 and 516 nm, respectively The A laidlawii B cells were grown and cell ... temperatures and in the presence of agents which often alter protein conformation There is good evidence from studies of the interaction of GS and its analogs with bacterial cells that the destruction of ... analogs of GS, their relative potencies at perturbing the organization and increasing the permeability of phospholipid bilayer model membranes, and of causing the lysis of A laidlawii B and human...
Ngày tải lên: 21/02/2014, 01:21
Báo cáo khoa học: Mutual effects of proton and sodium chloride on oxygenation of liganded human hemoglobin Oxygen affinities of the a and b subunits potx
... association rate constant of O2 rebinding and the 6110 quantum yield of BR for the a and b subunits within the liganded dimer and tetramer of hemoglobin were determined Second, pH and NaCl effects on ... concentrations of 0.1, 0.5, 1.0 and 2.0 m The rate constant of BR and the quantum yield of BR, in the presence of NaCl, gave a direct evidence of significant functional heterogeneity for the a and b subunits ... shown by Imai and Yonetani [23] by determination of the hemoglobin affinity for the fourth ligand molecule The purpose of this study was twofold First, the mutual effects of pH and NaCl on the...
Ngày tải lên: 16/03/2014, 14:20
Báo cáo khoa học: Prohibitin is expressed in pancreatic b-cells and protects against oxidative and proapoptotic effects of ethanol pdf
... proof of apoptosis, cleaved caspase-3 was determined in cell extracts by western blot (G) Representative blot of n = experiments showing 17 and 19 kDa caspase-3 cleavage bands and the levels of ... production of reactive oxygen species (ROS) and mitochondrial dysfunction [9,10] Increased ROS production is one of the earliest events in glucose intolerance and it may be a mechanism of pancreatic ... metabolism and ATP production, and increased ROS production and UCP2 levels These alterations occurred at a physiologically relevant ethanol level of 80 mm (368 mgÆdL)1) found in the blood of clinically...
Ngày tải lên: 29/03/2014, 08:20
báo cáo hóa học: " Pro-inflammatory gene expression and neurotoxic effects of activated microglia are attenuated by absence of CCAAT/enhancer binding protein b" potx
... treatment, and in nuclear levels of both activating (Full/LAP) and inhibitory (LIP) C/EBPb isoforms 24 h after treatment The increases in C/EBPb mRNA and protein induced by LPS and LPS+IFNg were of similar ... Croniger and Valeria Poli for the generous gift of C/EBPb knockout mice, Teresa Domingo and colleagues at animal facilities of the School of Pharmacy (University of Barcelona) for the professional ... Ascherio A: Use of ibuprofen and risk of Parkinson disease Neurology 2011, 76:863-869 59 in’t Veld BA, Ruitenberg A, Hofman A, Stricker BH, Breteler MM: Antihypertensive drugs and incidence of dementia:...
Ngày tải lên: 19/06/2014, 22:20
báo cáo hóa học:" Effects of alpha-calcitonin gene-related peptide on osteoprotegerin and receptor activator of nuclear factor-B ligand expression in MG-63 osteoblastlike cells exposed to polyethylene particles" doc
... osteoblasts and osteoclasts [12,13] RANKL and OPG are members of a ligand-receptor system that directly regulates osteoclast differentiation and bone resorption, and both are produced and secreted ... quantification of the gene of interest, which was expressed as the ratio of ‘concentration of the target’ to ‘concentration of b-actin’ Western Blot MG-63 cells were stimulated with and without ... in untreated group and the alpha-CGRP-incubated groups Densitometric quantification of RANKL in (B) a cell-particle ratio of 1:100 and (C) a cellparticle ratio of 1:500 with and without alpha-CGRP-incubation...
Ngày tải lên: 20/06/2014, 04:20
báo cáo hóa học:" Effects of alpha-calcitonin gene-related peptide on osteoprotegerin and receptor activator of nuclear factor-B ligand expression in MG-63 osteoblastlike cells exposed to polyethylene particles" pot
... osteoblasts and osteoclasts [12,13] RANKL and OPG are members of a ligand-receptor system that directly regulates osteoclast differentiation and bone resorption, and both are produced and secreted ... quantification of the gene of interest, which was expressed as the ratio of ‘concentration of the target’ to ‘concentration of b-actin’ Western Blot MG-63 cells were stimulated with and without ... in untreated group and the alpha-CGRP-incubated groups Densitometric quantification of RANKL in (B) a cell-particle ratio of 1:100 and (C) a cellparticle ratio of 1:500 with and without alpha-CGRP-incubation...
Ngày tải lên: 20/06/2014, 07:20
Báo cáo hóa học: "Effects of Pin-up Oxygen on [60]Fullerene for Enhanced Antioxidant Activity" pptx
... antioxidant activities %AOA [19] (= 100 {kobs of control - kobs of fullerene}/kobs of control) of PVP/C60 and C60O were 50% and 68% in 10 lM for antioxidant, and 73% and 81% in 30 lM, respectively Here, ... dependency of the pseudo-first-order rate constants, kobs, for the discoloration of b-carotene on the antioxidant concentration of PVP and CD complexes of C60 and oxidized C60O Here, the rate (Rf) of ... structure of major isomers of C60O2(cis-1 and e) Synthesis of PVP/C60 and its Oxidized Derivatives A toluene solution (10 mL) of fullerene C60 (8 mg) was added to an ethanol solution (5 mL) of PVP...
Ngày tải lên: 22/06/2014, 01:20
Báo cáo khoa học: "Influence of gestational age at exposure on the prenatal effects of gamma-radiation" pps
... of thoracic vertebrae Absence of ribs Fusion of ribs Bifurcation of ribs Shortening of ribs Displasia of sternebrae Missing of sternebrae Hypoplasia of sternebrae Curvature of tibia Absence of ... dilation of renal pelvis Fig Malformed head section of mouse fetus: dilation of lateral ventricles Fig Malformed digits of mouse fetus: ectrodactyly tion of the cerebral ventricle (Fig 2), and dilatation ... [11] and Rugh and Wohlfromm [28], and supports the earlier conclusions of Russell [29] and others [25, 33, 37] that the period of organogenesis is less sensitive to the lethal effects of radiation...
Ngày tải lên: 07/08/2014, 14:23
Báo cáo khoa học: " Dose-Incidence Relationships on the Prenatal Effects of Gamma-Radiation in Mice" pdf
... Fusion of thoracic vertebrae Absence of ribs Fusion of ribs Wavy ribs Hypoplasia of ribs Displasia of sternebrae Missing of sternebrae Hypoplasia of sternebrae Curvature of tibia Absence of metatarsal ... after exposure to different doses of gamma-ray on 11.5 day of gestation Dose (Gy) Observations No of mother No of implants No of embryonic death No of fetal death No of resorption Prenatal mortality ... dilatation of cerebral ventricle, dilatation of renal pelvis and abnormalities of the extremities and tail With increasing radiation dose, cleft palate, dilatation of cerebral ventricle and abnormalities...
Ngày tải lên: 07/08/2014, 15:20
Báo cáo khoa học: " Modulatory effects of chitosan adipate on the T and B lymphocyte subsets in mice" pps
... ralucillof nairavo htiw desongaid swoC gnilluc dna ecnamrofrep evitcudorper fo noitaulavE ytirap a htiw swoc ni naht )10.0 < ( deyaled ylsuounitnoc erom saw rehgih ro fo seitirap htiw swoc rof seirevocer ... gnilluc rof snosaeR N ellieraB ,C nohciruoF ,F uaeduaeB ,H sregeeS 43 9991 ,yraC ,tsnI SAS ,1.8 esaeleR ,metsyS SAS SAS 33 492-972 ,14 ,9991 deM teV verP swoc erihsryA hsinniF ni gnilluc no ecnamrofrep ... sesac dedulcni sitirtemodne ,eroferehT sngis lacinilc rehto tuohtiw ro htiw noitanimaxe latcer yb devresbo suretu degralne na dna egrahcsid yduolc ;sngis lacinilc gniwollof eht fo ecneserp eht yb...
Ngày tải lên: 07/08/2014, 18:21
Báo cáo khoa học: "The Akt-inhibitor Erufosine induces apoptotic cell death in prostate cancer cells and increases the short term effects of ionizing radiation" pot
... to the design of the study VJ performed conception and design of the study and substantially contributed to interpretation of data, drafting and critical revision of the manuscript and final approval ... membrane lipid composition and the formation of lipid second messengers, thereby affecting the growth, cell cycle progression, and survival of tumor cells without any direct Page of 12 effects on the ... apoptosis in tumor cells and their ability to increase cytotoxic efficacy of chemotherapy and radiotherapy in preclinical investigations [10-12] Induction of apoptosis by ErPC3 and related drugs occurs...
Ngày tải lên: 09/08/2014, 09:20
Báo cáo khoa học: "Effects of radiation therapy on tissue and serum concentrations of tumour associated trypsin inhibitor and their prognostic significance in rectal cancer patients" doc
... http://www.ro-journal.com/content/6/1/100 Page of 10 Figure Prognostic value of TATI concentrations in tumour tissue and serum ROC curves showing estimations of the prognostic value of t-TATI in surgically obtained tissue (A) and s-TATI ... collection of tissue samples and data AB participated in the conception of the study, BN assisted with the TMA construction and revision of the manuscript, UHS participated in revision of the manuscript, ... in the conception and design of the study, LBJ participated in the collection of tissue samples, data and revised the manuscript, KJ participated in the conception and design of the study, statistical...
Ngày tải lên: 09/08/2014, 09:21
Báo cáo y học: "Short- and long-term effects of anti-CD20 treatment on B cell ontogeny in bone marrow of patients with rheumatoid arthritis" ppsx
... (Three Star Inc., Ashland, OR, USA) Collection of blood and BM samples Heparinized blood and BM aspirates of a volume of 10 ml each were obtained at baseline (n = 37) Blood and BM sampling was ... lack of CD20 and this may be a reason for their survival in bone marrow [52-54] In our group of patients, we used a combination of CD38 and IgD, as a complement to the analysis of CD27 and IgD, ... Accumulation of immature subset of B cells in BM long after rituximab treatment We found a proportional increase of immature and transitional (CD38++IgD-, P = 0.002) and a reduction of Bm5 cells...
Ngày tải lên: 09/08/2014, 14:22
Báo cáo y học: "Anti-inflammatory and arthritic effects of thiacremonone, a novel sulfurcompound isolated from garlic via inhibition of NF-κB" pptx
... supershift of the DNA-binding activities of NF-κB upon addition of anti-p50 antibody, and the suppressive effect of DTT and glutathione on thiacremononeinduced inhibition of DNA-binding activity of NF-κB ... modulation of cysteine residues of the p50 subunit of NF-κB Discussion The activation of iNOS catalyzes the formation of a large amount of NO, which plays a key role in the pathogenesis of a variety of ... expression of iNOS and COX-2 (Figure 4c) It also suppressed the activation of NF-κB DNA-binding activity (Figure 4d) as well as the nuclear translocation of p50 and p65 and phosphorylation of IκBα...
Ngày tải lên: 09/08/2014, 14:22
Báo cáo y học: "Chemokine receptor expression and functional effects of chemokines on B cells: implication in the pathogenesis of rheumatoid arthritis" ppt
... grants-in-aid from the Ministry of Health, Labor and Welfare, and the Ministry of Education, Science, Sports and Culture, Japan, and the Japanese Ministry of Education, Global Center of Excellence (GCOE) ... peripheral B cells of both normals and subjects with RA, and CXCL12 enhanced the expression of ICOSL on both normal and RA B cells In contrast, the effect of CCL20, CCL19 and CCL21 was not significant ... cellular proliferation and expression of cytokines and activation markers by peripheral blood T cells [36,37], and that CCL2, CCL5 and CXCL12 upregulated the expression of cytokines and chemokines by...
Ngày tải lên: 09/08/2014, 14:22