data interpretation the holy grail of immunotoxicology

... 74% of the cases; residue 186 an Asn in 87% of the cases; and residue 334 a His in 80% of the cases [3] In addition, residue 54 is a Pro in 89% of the cases The importance of the identity of the ... we reach the conclusion that the substitutions in the shutter region affect the rate of latency transition by affecting the rate of passage of the RCL through the gate region Based on the aminoacid ... wild-type, and the use of this pH therefore allowed optimization of the difference in the effect of vitronectin on wild-type and the unstable variants The presence of vitronectin during the incubations...

Ngày tải lên: 22/02/2014, 07:20

... in-frame cloning of the genes While the BamHI sites introduced in the 3¢-UTR of the genes did not affect the resulting amino acid sequences, the introduction of NheI or NcoI sites next to the start ... during the purification of the recombinant protein The molecular mass data immediately suggested a phosphorylation of HpdC, which could affect the oligomeric structure and complex stability of the ... are shaded grey The amino acid sequence of HpdC is shown in bold letters together with the C-terminal end of HpdB and the N-terminal of HpdA sequences of the resulting proteins (MSQS to MASS in...

Ngày tải lên: 07/03/2014, 15:20

... boldine and laurolitsine [10] In the course of the systematic study of Litsea in Indochina, monoterpenes, sesquiterpenes and other components of the leaf oil of Litsea glutinosa from Ha Tinh ... lines in vitro Chemical examination of the BuOH extract of the leaves and twigs of Litsea glutinosa collected from Xishuangbanna resulted in the isolation of two new aporphine alkaloids, namely ... Journal of Science, Natural Sciences and Technology 26 (2010) 161-164 negative bacteria The results justify the reported uses in diarrhea and dysentery [9] The BuOH extract of the leaves and twigs of...

Ngày tải lên: 22/03/2014, 09:20

... expressed as a percentage of the total radioactivity in the cells at the end of the loading period (time 0) and are the mean of three separate experiments Error bars show the SEM The efflux curves were ... about the effects of CMR on NF-jB activity in macrophages The composition of the diet is known to be important in the development of atherosclerosis [24–26], and a major dietary determinant is the ... and no significant changes were observed with any of the four types of CRLPs at the other time points tested (data not shown) The total IjBa content of THP-1 macrophages after treatment with palm,...

Ngày tải lên: 23/03/2014, 04:20

... stages varied with the histologic type of the tumor The largest proportion of testis tumors diagnosed in Stage I were seminomas (85.8%) Choriocarcinomas had the smallest proportion of Stage I tumors ... remains one of the most highly curable malignant neoplasms Additional research is needed to understand the reasons for the differences in the stage distribution of tumors according to race and the poorer ... staged within the SEER data using the categories in situ, localized, regional, distant, and unstaged Staging information on the cancer is also contained within the 10-digit Extent of Disease (EOD)...

Ngày tải lên: 29/03/2014, 01:20

... have completed the proof of Theorem 3.1 Using the proof method for Theorem 3.1 and Lemma 2.8, we get the following theorem 1, 2, , n, be a smooth differential form satisfying the ATheorem 3.2 ... constants, the fixed cube Q0 ⊂ Ω, the cubes Qi ⊂ Ω, the constant N > appeared in Lemma 2.3, and xQi is the center of Qi Proof First, we use Lemma 2.3 for the bounded and convex δ-John domain Ω There ... keep working on the same topic and derive global estimates for the singular integrals of these composite operators in δ-John domains The purpose of this paper is to estimate the Poincar´ type...

Ngày tải lên: 21/06/2014, 18:20

... profile, i.e Of+ Oh horizons, is 72 mm) The organic profile is highly acidic with pH values of 3.0 and 2.6 (in KCl) and Ca2+/H+ quotients of 0.2 in the equilibrium soil solution of the upper (Of) ... of the studied branch roots to obtain a crude estimate of the water potential at the root surface (Ψsurface) The tensiometer data were taken every 15 and averaged over the three instruments The ... tips [4, 5], or other factors have inhibited further growth of the root apex resulting in a comparably high age of the rootlets close to the tip In the peridermal cell walls of spruce roots,...

Ngày tải lên: 08/08/2014, 01:21

... on the eleventh dorsal vertebra A percutaneous biopsy showed involvement of mesothelioma, but the histologic pattern of the lesion was undifferentiated Radiotherapy on the lumbar area was then ... dissection There was no peritoneal involvement The histologic aspect was epithelioid mesothelioma with necrosis and invasion of both the capsule and small vessels A recurrence of the nephrotic ... on the following elements [8] First, symptomatic treatment of the nephrotic syndrome with sodium and water restriction and diuretic therapy is justified In the majority of patients, the use of...

Ngày tải lên: 11/08/2014, 17:21

... representation of the PCA analysis of DNR The X-axis is the first principal component (PC1) and Y-axis is the second principal component (PC2) The diameters of the circles indicate DNRs The plots ... Outline of the experimental field and the water treatment apparatus - 422 - Journal of Water and Environment Technology, Vol 8, No.4, 2010 Paddy field The characteristics of the paddy field and the ... important indicator of the stabilization of denitrification activity in the water treatment apparatus and will help with the water treatment apparatus improvement Furthermore, the types of quinone related...

Ngày tải lên: 05/09/2013, 10:15

... gene including the 161 bp of promoter region joined with the first 12 bp of the ORF region was amplified from the DNA of the cosmid clone #9 using the same direct primer as for the CK2btes–b-galactosidase ... make the CK2btes–b-galactosidase fusion construct, a 934-bp fragment of the CK2btes gene including the 161 bp of promoter region linked to the whole ORF was PCRamplified from the DNA of the cosmid ... [22] To generate the CK2btes ÔantisenseÕ construct, the XhoI fragment of the CK2btes cDNA #421 corresponding to the 12–700 bp region of the sequence of cDNA #911 (one XhoI site in the cDNA #421...

Ngày tải lên: 21/02/2014, 15:20

... which anchor the protein in the membrane The position and function of the long C-terminal tail on the other hand remains a matter of controversy [10,11,13–15] According to one hypothesis, the hydrophilic ... because the demand of the chloroplast is ‘sensed’ inside the organelle, the IEM is closest to the origin of the signal, and thus regulation at the Tic complex could be one of the fastest ways to ... is the recruitment of FNR from the stroma or even thylakoids to the Tic complex in order to become part of the hypothetical electron transfer chain mentioned above However, the involvement of the...

Ngày tải lên: 07/03/2014, 03:20

Ngày tải lên: 09/03/2014, 14:20

... localization of the endogenous GLUT8 in testis, the nature of its sorting, and the interaction of its Nterminal dileucine motif with the various AP subunits The [DE]XXXL[LI] signal of GLUT8 has ... resolve some of these discrepancies in order to (a) identify the subcellular localization of GLUT8 in testis, (b) elucidate the role of APs in GLUT8 sorting, and (c) understand the role of the EXXXLL ... contrast, translocation of GLUT8 to the plasma membrane in response to insulin or other stimuli was not observed in several other in vitro studies [4–7] With the exception of the myo-inositol transporter...

Ngày tải lên: 16/03/2014, 02:20

... papers as a result of this correspondence The protocol proposed the use of 13 databases for the search Upon closer inspection it was decided that the content of 10 of the databases were not directly ... nutrient content may then be further increased during the storage, transportation and preparation of the foodstuffs prior to reaching the plate of the consumer An understanding of the various factors ... provided the following: - a clear definition, in the Introduction or Methods section of the paper, of the organic production methods of the crop or livestock product analysed (including the name of...

Ngày tải lên: 28/03/2014, 19:20

... (designated R4) in the construct F2 resulted in the abolishment of 80% of the relative luciferase activity, despite the presence of exon and the upstream sequence (Fig 3A) A further deletion in ... from the F1 fragment that contained the upstream regulation region, exon and kb of the Rnf33 intron; the sequences were cloned in front of the promoter-less luciferase gene of pGL-Basic In the ... construct F3 confirmed the importance of R4, albeit with possible further contribution outside the R4 sequence When one to three copies of the 305-bp R4 sequence were cloned in either the forward or...

Ngày tải lên: 29/03/2014, 00:20

... there are no reports about the chemical content and biological effect of the essential oils of L resedifolia There no reports on the essential oils of the species of the genus launaea except that ... order of their elution on the HP-5MS non-polar column (Table 1) A total of 19 compounds were identified, representing 86.68% of the total oil The esters made up the largest component of the oil ... noteworthy that the results of this study may be considered as the first report on the composition of the essential oils of this endemic species 2.6 Antimicrobial activity The quantification of antibacterial...

Ngày tải lên: 20/06/2014, 20:20

... there are no reports about the chemical content and biological effect of the essential oils of L resedifolia There no reports on the essential oils of the species of the genus launaea except that ... order of their elution on the HP-5MS non-polar column (Table 1) A total of 19 compounds were identified, representing 86.68% of the total oil The esters made up the largest component of the oil ... noteworthy that the results of this study may be considered as the first report on the composition of the essential oils of this endemic species 2.6 Antimicrobial activity The quantification of antibacterial...

Ngày tải lên: 21/06/2014, 17:20

... reported in the literature [12] and stored on the MS library (NIST database) The concentration of the identified compounds was computed from the GC peak total area without any correction factor The compounds ... noteworthy that the results of this study may be considered as the first report on the composition of the essential oils of this endemic species Chahma A voucher specimen was deposited at the herbarium ... Esters Aldehydes Page of demonstrated by the size of the microorganism growth inhibition zone around the filter paper disk, which is typically expressed as the diameter of the inhibition zone in...

Ngày tải lên: 21/06/2014, 19:20

... the proof below Furthermore, neither this result nor its proof has appeared previously in any literature that is known to the authors, though it seems to be part of the folklore The proof of this ... Lemma 3.3 The second statement in Theorem 3.5 follows Proof of Theorem 2.1 In the proof of Theorem 2.1, part (B), we will use part of the following lemma, which is obtained by straightforward ... from which the statement of Theorem 2.1, part (B), follows By restricting the values of u, one obtains various necessary conditions for boundedness of Cφ from part (B) of Theorem 2.1 Two of such...

Ngày tải lên: 22/06/2014, 22:20