... hydrolysis kcat ⁄ Km Number CG Substrates Derived from SERPINB1 S1¢ specificity ABZ-GIATFCMLMPEQ-EDDnp ABZ-GIATFDMLMPEQ-EDDnp ABZ-GIATFRMLMPEQ-EDDnp ABZ-GIATFSMLMPEQ-EDDnp ABZ-GIATFWMLMPEQ-EDDnp S2¢ ... library (Fig 1) [33–35] Thus, CG and chymase could accommodate a negative P2¢ residue, although via a different mechanism that involves Arg41 and Lys192 in CG and Arg143 and Lys192 in chymase We ... respectively Igepal CA-630 was obtained from Sigma (St Louis, MO, USA) Z-GLF-CMK was obtained from Enzyme System Products (Livermore, CA, USA) N,N-dimethylformamide and acetonitrile were obtained from Merck...
Ngày tải lên: 28/03/2014, 22:20
... following day, cells were stimulated with either aCD3 mAb (UCHT1 clone; 50-500 ng/ml, BD Biosciences, San Diego, CA) or Thymoglobulin® (50-500 ng/ml, Genzyme Corp., Cambridge, MA) and recombinant human ... immune suppressive drugs cyclosporine A and FK506 [5] Conversely, the anti-tumour activity of CIK cells mainly relies on the engagement of NK Group 2, member D (NKG2D) by NKG2D ligands on tumour ... relapsing after allogeneic stem cell transplantation: a phase I study Haematologica 2007, 92:952-959 Schmidt-Wolf IG, Negrin RS, Kiem HP, Blume KG, Weissman IL: Use of a SCID mouse/human lymphoma model...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo toán học: "Finitely connected domains G, representations of $H^infty(G)$, and invariant subspaces " docx
Ngày tải lên: 05/08/2014, 10:20
Báo cáo toán học: "On the function “sandwiched” between α(G) and χ(G) V. Y" ppt
... combinatorics (1997), #R19 Theorem For all graphs G α (G) = min{ rank(B) |B ∈ B (G) } implies α (G) = χ (G) Proof Let S = {v1 , v2 , , vα (G) } be the stable set of G, S = V (G) \ S and B ∈ B (G) ... the Petersen graph G We have α (G) = ϑ (G) = 4, χ (G) = Hence, min{ rank(B) |B ∈ B (G) } = There is a graph G such that α (G) < min{ rank(B) |B ∈ B (G) } < χ (G) Let V (G) = 2{1,2,3,4,5,6} and u − v iff ... (1979), 1–7 Martin Gr¨tschel, L´szl´ Lov´sz, and Alexander Schrijver, Geometric Algorithms and Combinao a o a torial Optimization (Springer-Verlag, 1988) Donald E.Knuth, “The Sandwich Theorem”, Electronic...
Ngày tải lên: 07/08/2014, 06:20
Báo cáo y học: "CTLA-4 +49A/G and CT60 gene polymorphisms in primary Sjögren syndrome" docx
... isolation of genomic DNA from peripheral blood mononuclear cells, CTLA-4 CT60 and +49A /G polymorphisms were genotyped by restriction fragment length polymorphism with the use of BbvI (+49A /G) and NlaIII ... PL and DC supervised genotyping and contributed to DNA samples collection MA and CC performed genotyping NC performed PHASE analyses EH, XP, and JS contributed to DNA samples collection XM and ... investigated CTLA-4 +49A /G polymorphism genotypic distribution among males and females in the control group and found that it was not statistically different (p = 0.1), thus excluding any possible gender...
Ngày tải lên: 09/08/2014, 10:20
HLA g and KIR2DL4 alleles haplotypes and risk of pre eclampsia in a malay population
... CCG GAG GAG GCA TTC ACA TTC ACA TTC GCA GAG GAG CCG KIR2DL4 *00501 TGT GCA GAG GAG CCG TTC KIR2DL4 *00502 TGT GCA GAG GAG CCG TTC GAT CTG GCA GAG GAG CCG CTG GCA GAG GAG CCG GCA GAG GAG CCG * KIR2DL4 ... GCC CTG GAG TAC CAC CAC GCA ACG CCG GGC GGT AGA AGG TCC ACG CGG GCG CAG CCG GCC CAC GGA CTC CCA CAT CCA GGT GCT GGT CAT CCA CCA 926 AGG CAT GGT GAA GCG GCT CCA CCA CCA CGA CAT CAT CAT CAT CGG ... KIR2DL4 *0080101 GCA GAG GAG CCG * KIR2DL4 *0080102 GCA GAG GAG CCG * KIR2DL4 *0080103 GCA GAG GAG CCG * KIR2DL4 *0080104 GCA GAG GAG CCG * KIR2DL4 *0080201 GCA GAG CCG * GAG CCG GAG CCG CGC KIR2DL4...
Ngày tải lên: 22/10/2015, 21:08
A facile construction of the tricyclic 5 7 6 scaffold of fungi derived diterpenoids the rst total synthesisof (±) heptemerone g and a new approach to danishefsky s intermediate for a guanacastepene
... Naganawa, Y.; Maruoka, K J Am Chem Soc 2009, 131, 6614–6617; (c) Malik, C K.; Ghosh, S Org Lett 2007, 9, 2537–2540; (d) McGowan, C A.; Schmieder, A K.; Roberts, L.; Greaney, M F Org Biomol Chem 2007, ... J Org Chem 2003, 68, 1030–1042 Mehta, G. ; Pallavi, K.; Umarye, J D Chem Commun 2005, 4456–4458 Iimura, S.; Overman, L E.; Paulini, R.; Zakarian, A J Am Chem Soc 2006, 128, 13095–13101 10 Miller, ... triethylamine to give acetate 26 Finally, removal of the ketal protecting group afforded heptemerone G (2) The HRMS, 1H NMR (500 MHz, CDCl3), IR and UV spectra confirmed the structure The 1H NMR spectrum...
Ngày tải lên: 26/01/2016, 09:27
Azar 3e und g and using engr chb
... lighted/lit lost made meant met mislaid mistaken paid put quit read rid ridden rung *In British English: get-got-got In American English: get-got-gotunlgot ** Hang is a regular verb when it means ... reference grammar for students of English as a second or foreign language tilfith a minimum of terminology and a broad table of contents, it seeksto make essentialgrammar understandableand easily ... structure usagebetweenAmerican and British English are noted throughout the text The differences are few and relatively insignificant Tlre Tbacher\Guide for Understandingand Using English Grammar contains...
Ngày tải lên: 24/04/2016, 00:12
Azar 3e und g and using engr SB
... In memoriam To my wonderful parents, Frunces Nies Schrampfer and WiUiam H Schrampfer, who set me on my path PREFACE TO THE THlRD EDITION ... PROGRESSIVE 47 Chapter FUTURE TIME 4-1 4-2 4-3 4-4 4-5 4-6 4-7 SIMPLE FUTURE: WILL AND BE GOING TO 51 WILL vs BE GOING T ... 2-4 AMIISIARE BEING + ADJECTIVE 17 2-5 REGULAR AND IRREGULAR VERBS 19 2-6 REGULARVERBS: PRONUNCIATION O F -ED ENDINGS...
Ngày tải lên: 24/04/2016, 00:12
Báo cáo y học: "Subcutaneous Immunoglobulin-G Replacement Therapy with Preparations Currently Available in the United States for Intravenous or Intramuscular Use: Reasons and Regimens" docx
... allows convenient administration of larger doses of IgG Subcutaneous Immunoglobulin- G Replacement Therapy — Chouksey et al IGIV SCIG Figure Trough serum immunoglobulin G (IgG) concentrations in ... Smith CIE Home treatment of hypogammaglobulinemia with subcutaneous gammaglobulin by rapid infusion Lancet 1991;338:162–6 Berger M Subcutaneous immunoglobulin replacement in primary immunodeficiencies ... participating study site) Information on age, weight, gender, immunologic diagnosis, previous treatment regimen, and complications of previous treatment regimens were recorded In addition, serum IgG levels...
Ngày tải lên: 08/08/2014, 20:23
Báo cáo y học: " Immunoglobulin G galactosylation and sialylation are associated with pregnancy-induced improvement of rheumatoid arthritis and the postpartum flare: results from a large prospective cohort study" pot
... van de Geijn et al Figure Mean galactosylation of IgG1 and IgG2 in cases and controls during pregnancy and postpartum IgG1 (a) and IgG2 (b) galactosylation levels (in postpartum percentages) increase ... bisecting GlcNAc was not influenced by pregnancy or postpartum and was similar in cases (range min-max IgG1 13.7 to 14.7%, range min-max IgG2 13.2 to 14.3%) and controls (range min-max IgG1 13.7 ... Glycosylation profiling of immunoglobulin G (IgG) subclasses from human serum Proteomics 2007, 7:4070-4081 Nimmerjahn F, Ravetch JV: Divergent immunoglobulin g subclass activity through selective Fc...
Ngày tải lên: 12/08/2014, 11:22
Báo cáo khoa học: Binding of hemolin to bacterial lipopolysaccharide and lipoteichoic acid An immunoglobulin superfamily member from insects as a pattern-recognition receptor doc
... 25 mM Tris/ HCl, 137 mM NaCl and mM KCl, pH 7.0) and used for the agglutination assay Hemolin at 0.5 mgÆmL)1 or BSA at 1.0 mgÆmL)1 (as a control) was used in agglutination of micro-organisms ... hemolin-binding site Aggregation of micro-organisms by hemolin and the ability of hemolin to bind to hemocytes may promote phagocytosis and the formation of hemocyte nodules to clear micro-organisms ... P4 (Hemolin) from Manduca sexta: a member of the immunoglobulin superfamily which can inhibit hemocyte aggregation Arch Insect Biochem Physiol 18, 285–300 Su, X.-D., Gastinel, L.N., Vaughn, D.E.,...
Ngày tải lên: 31/03/2014, 09:20
Báo cáo khoa học: " Effective methods for the production of immunoglobulin Y using immunogens of Bordetella bronchiseptica , Pasteurella multocida and Actinobacillus pleuropneumoniae" docx
... extracted from the eggs as described by previous studies (24, 26) Briefly, egg yolk was separated from the egg white and homogenized after mixing with an equal volume of PBS The homogenized egg yolk ... inoculation Immunological assay Antibody titers in egg yolks and sera were measured by ELISA OMPs and DNT from B bronchiseptica and P multocida D:4, OMPs from A pleuropneumoniae serotypes and and IROMPs ... (Fig and 4) Immune responses to P multocida A:3 Immune response profiles against P multocida A:3 in egg yolks and the sera of hens immunized with P multocida A:3 alone and P multocida A:3 combined...
Ngày tải lên: 07/08/2014, 15:20
Báo cáo khoa học: "Effects of Combination Dietary Conjugated Linoleic Acid with Vitamin A (Retinol) and Selenium on the Response of the Immunoglobulin Productivity in Mice" pdf
... [11] Serum immunoglobulin E is an immunoglobulin of major importance in mechanisms against parasites and in the immunopathogenesis of allergic disease In this experiment the levels of immunoglobulin ... supplemented with 0.5% CLA and vitamins A: 300 IU/kg/ day, D: 100 IU/kg/day, E: mg/kg/day CVA2: groups fed diet supplemented with 1.5% CLA and vitamins A: 300 IU/kg/ day, D: 100 IU/kg/day, E: mg/kg/day ... supplemented with 0.5% CLA and vitamins A: 300 IU/kg/ day, D: 100 IU/kg/day, E: mg/kg/day CVA2: groups fed diet supplemented with 1.5% CLA and vitamins A: 300 IU/kg/ day, D: 100 IU/kg/day, E: mg/kg/day...
Ngày tải lên: 07/08/2014, 17:22
Báo cáo khoa học: "Differences in the serum immunoglobulin concentrations between dairy and beef calves from birth to 14 days of age" pdf
... radial immunodiffusion (SRID) test (VMRDTM Inc., Pullman, USA) [1] Data analysis The serum IgG, IgM and IgA concentrations at each sampling time for both dairy and beef calves were compared using Student’s ... colostral immunoglobulins to the newborn calf Immunology 1969, 16, 293-299 11 Logan E F and Gibson T Serum immunoglobulin levels in suckled beef calves Vet Rec 1975, 97, 229-230 12 Logan E F., McBeath ... Quigley J D., Martin K R., Bemis D A., Potgieter L N D., Reinemeyer C R., Rohrbach B W., Dowlen H H and Lamar K C Effects of housing and colostrum feeding on serum immunoglobulins, growth, and fecal...
Ngày tải lên: 07/08/2014, 17:22
Báo cáo y học: "Abnormalities of B cell phenotype, immunoglobulin gene expression and the emergence of autoimmunity in Sjögren’s syndrome" pdf
... Skovgaard GL, Bohr VA, Gearhart PJ: Third complementarity-determining region of mutated VH immunoglobulin genes contains shorter V, D, J, P, and N components than non-mutated genes Immunology ... Human immunoglobulin (Ig )M+ IgD+ peripheral blood B cells expressing the CD27 cell surface antigen carry somatically mutated variable region genes: CD27 as a general marker for somatically mutated ... and chemokines in pSS In patients with pSS the salivary and lacrimal glands are the main target organs for the immune system and, at least in part, subsequent autoimmune-mediated tissue damage...
Ngày tải lên: 09/08/2014, 01:21
Báo cáo y học: "Intravenous immunoglobulin treatment of four patients with juvenile polyarticular arthritis associated with persistent parvovirus B19 infection and antiphospholipid antibodies" pptx
... containing free and immunocomplexed B19 particles, remains unclear IVIG treatment might be associated with an enhanced formation of immunoglobulin complexes, resulting in the induction of complement and ... Laboratory and clinical parameters of the patients during IVIG therapy ESR WBC/ RBC/ Hb CRP Patient Sample (mm/h) ml ml (g/ dl) (mg/dl) Total CK Arthritis IgG (U/l) (joints) (mg/dl) B19 DNA Serum SF IgG ... according to the American Rheumatism Association criteria Detection of B19-specific antibodies, immunocomplexes, genomes and anti-PL IgG Patient samples were analysed for IgG and IgM against the...
Ngày tải lên: 09/08/2014, 01:23
Báo cáo y học: "Analysis of immunoglobulin light chain rearrangements in the salivary gland and blood of a patient with Sjögren’s syndrome" pptx
... hydroxychloroquine and mg prednisone daily at the time of analysis After developing parotid gland enlargement, lymphoma of the parotid gland was excluded by partial parotidectomy and histological examination ... hypermutation in Salivary gland mucosa-associated lymphoid tissue-type lymphomas Blood 1997, 89:3335-3344 22 Amft N, Bowman SJ: Chemokines and cell trafficking in Sjogren’s syndrome Scand J Immunol ... 161:2895-2905 Markusse HM, Otten HG, Vroom TM, Smeets TJ, Fokkens N, Breedveld FC: Rheumatoid factor isotypes in serum and salivary fluid of patients with primary Sjögren’s syndrome Clin Immunol Immunpathol...
Ngày tải lên: 09/08/2014, 03:24
Báo cáo y học: "Therapeutic effects of antibodies to tumor necrosis factor-α, interleukin-6 and cytotoxic T-lymphocyte antigen 4 immunoglobulin in mice with glucose-6-phosphate isomerase induced arthritis" docx
... T-lymphocyte antigen immunoglobulin (CTLA-4Ig; g/ ml), anti-inducible co-stimulator (ICOS) mAb (0.5 g/ ml), and anti-CD40L mAb (1 g/ ml) were also used to block co-stimulatory pathways, and the ... splenocytes and cytometric bead array Spleens were dissected from immunized DBA/1 or B6 mice (on day after immunization) and immediately immersed in phosphate-buffered saline (PBS; Gibco, Grand Island, ... centrifuged again, and resuspended in RPMI (Gibco, Grand Island, NY, USA) For culture, we used RPMI supplemented with 100 g/ ml streptomycin, 100 U/ml penicillin, 10% fetal bovine serum, and 50 μM...
Ngày tải lên: 09/08/2014, 10:23