cxcr4 cxcl12 in nonsmallcell lung cancer metastasis to the brain

Ngày tải lên: 13/08/2014, 14:20

... and to the pattern of relapse occurrence (inside the first postoperative year or later). Chi-square test.was used to assess the influence of the per- centage of N2 lesions to the length of the interval ... occurred in 26%, 70% and 4% patients respectively. Postoperative cancer relapse occurred in 27/35(77.1%) pts. in the stage IIIA and in 21/40(52.55) pts in the stage IIB. In none of four pts. in the ... occurred in 26%, 70% and 4% patients respectively. Postoperative cancer relapse occurred in 27/35(77.1%) pts. in the stage IIIA and in 21/40(52.5) pts in the stage IIB. In none of four pts. in the...

Ngày tải lên: 09/08/2014, 04:21

... take the tumour motion into account. However, similar to the reasoning given for the ITV to PTV margin, a minimum margin of 3 mm should be used for the incorporation of the other uncertainties. Organs ... for purposes of contouring will begin at the level of the inferior aspect of the aortic arch (aorto-pulmonary window) and extend inferiorly to the apex of the heart. The defined ipsilateral brachial ... proto- cols [17,18]. In order to facilitate the clinical use of these recommenda- tions, we divided the process of implementing high-dose radiotherapy into the following headings: CT scanning and...

Ngày tải lên: 09/08/2014, 09:22

... Serwatowski P, et al.: Phase III Study of Erlotinib in Combination With Cisplatin and Gemcitabine in Advanced Non-Small-Cell Lung Cancer: The Tarceva Lung Cancer Investigation Trial. J Clin ... erlotinib in advanced non-small cell lung cancer (NSCLC) patients (p) with mutations in the tyrosine kinase (TK) domain of the epidermal growth factor receptor (EGFR). J Clin Oncol (Meeting ... of any cumulative toxicity in the subgroup analy- sis. The rates of grade 3 and 4 toxicities in the pemetrexed arm were low. Taking that into consideration, the differ- ence in the deterioration...

Ngày tải lên: 10/08/2014, 22:21

... finding at the time of pancreaticoduodenectomy in pancreatic carcinoma of the head and uncinate process is the invasion of the superior mesenteric ve in (SMV) or superior mesenteric portal vein ... Christoph Seidlmayer 3 Abstract Introduction: Tumors of the pancreatic head can infiltrate the superior mesenteric vein. In such cases, the deep veins of the lower limbs can serve as suitable autologous ... leading to functional venous reflux, thus underscoring the clinical utility of compres- sion stockings. These pathophysiologic features could explain why SFV harvest is so well to lerated in contrast to...

Ngày tải lên: 10/08/2014, 23:20

Ngày tải lên: 13/08/2014, 11:22

Ngày tải lên: 14/08/2014, 19:22

Ngày tải lên: 07/09/2013, 13:06

... disap- pointing since 80% of the current sales are to the urban middle class rather than to the rural poor, the primary target of the original project. The size of the BOP market, like any other ... considering the BOP opportunity in India, Essilor first went to Indian opticians and tried to get them engaged in the project. However, most of them rejected the idea, arguing that it was too costly, ... operations. Examining these three cases in- depth yields several interesting insights on the key success factors for BOP initiatives. The BOP literature is full of exhorta- tions calling for a “revolution” in...

Ngày tải lên: 19/02/2014, 03:20

... subcloned into the pCR II TA cloning vector (Invitrogen, San Diego, CA, USA) and sequenced. The nt sequences were determined by the dideoxy chain-termination method using a Dye Terminator Cycle ... relative to the enzyme [38], were also found in all the snake enzymes. The unique cysteine-rich-terminus and inserted Ser in the Ca 2+ -binding site of amphibian DNases I [14], were not observed in the snake ... corres- ponding to the nt sequences of the cDNA from positions 28–48 and 867–885, respectively. The amplified fragment was ligated into the pcDNA3.1 (+) vector (Invitrogen) to construct the expression...

Ngày tải lên: 20/02/2014, 23:20

... CLAP with a phosphoprotein stain did not reveal phosphate additions to these proteins. Only lanes in the gel containing the known phosphoproteins ovalbumin, b-casein and pepsin gave a reaction. Thus, ... of the fasciclin I domains in CLAP with selected proteins in the protein database. The Conserved Domain Database of NCBI was screened with the protein coding sequence of clone 1 of CLAP and the ... the Fas I domains in the protein compared with 10 other fasciclin I-containing proteins. The most highly conserved sequences (containing more than four amino acids) are boxed, and the number below...

Ngày tải lên: 07/03/2014, 16:20

... page 80, showing the problems of theme selection (including kinds of predicator theme, adjunct theme, subject theme, non - wh theme, wh. theme, etc); theme more clearly expressed in the use of ... speakers of all the language communities) to understand the environment, to act on the others in it, and also to interpret the relevance of the first two purposes interims of the topics under ... behind rather greatly from the counter-part trainings in the region and the world over, it has gradually made good of these shortcomings and has in fact filled the gap mentioned above in...

Ngày tải lên: 28/03/2014, 11:20

... impingement (despite their negative MRI) or they were merely complaining of generalised shoulder pain following their neck injury. Pain radiating from the neck to the shoulder after whip- lash injuries ... pain following their neck injury as well as having four positive clinical tests as described above. If the injury was sustained in a Motor Vehicle Accident (MVA) the position of the patient in ... considered when the individual was complaining of pain and aching to the neck in the presence or absence of restriction of neck movements secondary to a hyper flexion/extension injury caused by their recent...

Ngày tải lên: 20/06/2014, 01:20

... F2L-gfp. The F2L gene in VV strain WR (shaded arrow in the top line) was replaced with the gfp gene driven by the synthetic E/L promoter (black arrow in the bottom line). The resulting virus was des- ignated ... deamina- tion of cytosine and can result in A:T transition mutations in one of the nascent strands [1]. Minimizing the incorpo- ration of these bases and excising those that arise prevents the ... of these viruses, or are related to differences in the animal models including route of infec- tion. In HSV, direct intracranial inoculation resulted in a 10-fold reduction in virulence of the...

Ngày tải lên: 20/06/2014, 01:20

... OF FACTORING METHODS OF FACTORING Factoring for each limit Factoring for each time Co-factoring 2 1. Motivation of the Study Credit activity of the banks in general and of the join stock ... co-guarantee, the other guarantee types. The types of credit cards included domestic and international cards. The type of factoring included having recourse right or not. The factoring method included ... and that the State can intervene in the economy through the state management tools and create an enabling environment to promote and ensure the market factor of stability, to maintain order...

Ngày tải lên: 16/07/2014, 15:29

... metastasis to the rectum. Findings in the patient reported here emphasize the importance of the relationship between urinary and gastrointestinal symptoms in detecting prostatic neoplasms in older ... [7]. Conclusion Findings in the patient reported here emphasize the importance of the relationship between urinary an d gas- trointestinal symptoms in detecting prostatic neoplasms in older male ... was referred to our urology facility after experiencing severe weight loss (30 kg in 3 months) and bleeding from the rectum, together with upper a bdominal pain and vomiting. Over the previous year,...

Ngày tải lên: 09/08/2014, 01:24

... metastases involving unusual sites many years after resection of the primary tumor. Proton therapy was found to be effective in treating RCC metastasis to the ciliary body in settings in which other treatment ... temsirolimus and interleukin-2 and intravitreal injections of bevacizumab) shows that the red mass had grown. (d) SLE photograph delineates the mass-lens adhesions prior to proton beam radiotherapy. (e) ... that involved the ciliary body, brain, lungs, liver, and pancreas. The ciliary body mass continued to grow despite sys- temic treatment with temsirolimus (mammalian target of rapamycin inhibitor)...

Ngày tải lên: 10/08/2014, 23:22

... Thin (3 mm) axial images were imported into the ADAC Pinnacle planning system (ADAC Labora- tories, Milpitas, CA, USA). In this case, IMRT was designed using an inverse-planning algorithm. The ... Photomicrograph of left parotid mass showing tumor cells of similar cytology to the original temporal mass infiltrating the parotid gland. Ductal structures characteristic of eccrine porocarcinoma ... about the role of adjuvant therapy in managing eccrine porocarcinomas. Radiation therapy should be considered within a multidisciplinary approach in patients with primary or recurrent eccrine...

Ngày tải lên: 11/08/2014, 12:20

Ngày tải lên: 11/08/2014, 14:21