current treatment of pah prostanoids phosphodiesterase 5 inhibitors and stimulators of soluble guanylate cyclase
Báo cáo y học: "Phosphodiesterase 5 inhibitors lower both portal and pulmonary pressure in portopulmonary hypertension: a case repor" pot
Ngày tải lên :
11/08/2014, 10:22
... 89 75 3.02 6.8 45 459 159 86 87 3 .51 7.9 39 344 147 97 93 1 45 100 69 3.33 7 .5 42 352 140 90 75 3 .56 8.0 42 360 10 10 70 .5 41.3 52 2 2020 120 37.0 35. 2 78.2 38.4 2240 130 33 .5 33.2 71.4 35. 3 51 4 ... distance was 52 2 m Arterial blood gas analysis before and after six-minute walking test showed normal paO2 (74 and 75 mmHg) and paCO2 ( 35 and 32 mmHg) After exclusion of other causes of pulmonary ... Journal of Medical Case Reports 2007, 1:46 Beta-blockers – the standard medical treatment of portal hypertension – worsen the prognosis of patients with PPHTN [3] Endothelin receptor blockers and...
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current treatment of hepatitis b 2008
Ngày tải lên :
13/08/2014, 09:44
... with hepatitis B: greater clinical and antiviral Gut 2008 ;57 :1 05 124 doi:10.1136/gut.20 05. 077891 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 efficacy for telbivudine ... 2008 ;57 :1 05 124 doi:10.1136/gut.20 05. 077891 140 141 142 143 144 1 45 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 Van Bommel F, Zollner B, Sarrazin C, et al Tenofovir ... 0 .5 mg Lamivudine 100 mg Telbivudine 600 mg 272 38% 25. 8 40% (5% ){ 39% (41%){ 20% (19%){ 27% 48 214 34% 24 .5 25% (14%){ 62% (28%){ 27% (32%){ 4% 355 62% 25. 4 38% 60% 18% 18% 83 463 56 % 25. 5 40%...
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Báo cáo khoa học: An internal ribosome entry site mediates the initiation of soluble guanylyl cyclase b2 mRNA translation potx
Ngày tải lên :
23/03/2014, 07:20
... Relative luciferase activity Folds of control (pGL3-Basic) 52 5 bp * 55 45 35 25 15 pGL3-basic β2 Aβ2 pSL3 pFLuc β2 A-β2 EIII-β2 C Ladder Plus (bp) 1000 850 650 50 0 pSL-3 pSL3-β2 pSL3-Aβ2 +RT pSL3-Aβ2 ... b2 5 -UTR contains an IRES A pCMV RLuc FLuc β2 5 UTR pSL3-β2 I II III PCR #1 729 bp PCR #2 52 5 bp IV A-β2 5 UTR II IV I pSL3-A-β2 52 5 bp 57 6 bp pSL3-EIII-β2 III pSL-3 B 60 50 40 30 422 bp 65 Relative ... of an IRES being identified in one of the sGC genes Results Cloning of the sGC b2 5 -UTRs The 5 -UTR of sGC b2 was isolated from human kidney RNA by RT-PCR Two cDNA fragments of 298 bp and 195...
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Thuốc chống viêm ức chế lipooxygenase và cyclooxygenase dùng dự phòng và điều trị ung th- (LOX an COX - inhibitors as adjunctive therapies in the prevention and treatment of cancer) ppt
Ngày tải lên :
20/03/2014, 03:20
... TCNCYH 25 (5) 2003 (+) Gluco corticoid Lipomodulin (-) phospholipase phospholipid Acid arachidonic (AA) A2 (-) AA cyclooxygenasse NSAID lipooxygenase 5- HPETE PG endoperoxyd H2 ... 1; số 1; 3/2002; trang - 37; SAGE Publications La Presse médicale; 17/3/2001/30/ số 10; trang 50 5 - 51 7 Drugs Quarterly; tập 4, số (Summer), 2000 Dầu olive 99 ... thấy curcumin có tác dụng chống tạo mạch Trên động vật, curcumin làm tăng thời gian 97 TCNCYH 25 (5) 2003 sống động vật gặm nhấm mà có ghép mảnh u ác, ức chế phát triển khối u, ngăn cản di Bớc...
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Báo cáo hóa học: " Current methods of diagnosis and treatment of scaphoid fractures" ppt
Ngày tải lên :
21/06/2014, 06:20
... consist of direct functional treatment, cast immobilisation of the fracture and joints, and operative treatment Direct functional treatment Figure Magnetic resonance imaging (patient D) of a waist ... 19 05 Gelberman RH, Menon J: The vascularity of the scaphoid bone J Hand Surg Am 1980, 5( 5) :50 8-13 Weber ER, Chao EY: An experimental approach to the mechanism of scaphoid waist fractures J Hand ... Page of Figure Treatment of scaphoid fractures Figure X-ray after percutaneous screw fixation of the scaphoid (patient F) Pseudo-arthrosis in case of an operative treatment depends on the type of...
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Báo cáo khoa học: "Curative treatment of oesophageal carcinoma: current options and future developments" pptx
Ngày tải lên :
09/08/2014, 09:20
... pattern of lymphatic spread and prognostic factors for long-term survival after surgical resection Ann Surg 20 05, 242(4) :56 6 -57 3, discussion 57 3 -56 5 Chang DTCC, Shen J, Su Z, Koong AC: Treatment of ... understanding of tumour response by research on molecular profiles to predict pCR and finally clinical Wolf et al Radiation Oncology 2011, 6 :55 http://www.ro-journal.com/content/6/1 /55 evaluation of ... sensitivity and specificity of 71% ( 95% CI, 62%-79%) and 93% ( 95% CI, 89%-97%) [51 ,52 ], which is crucial for the differentiation between locoregional and systemic disease In adenocarcinomas of the...
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Báo cáo y học: "Current approaches in the treatment of arthritic pain" pps
Ngày tải lên :
09/08/2014, 10:20
... Designing and evaluating complex interventions to improve health care BMJ 2007, 334: 455 - 459 49 Dieppe PA, Lohmander LS: Pathogenesis and management of pain in osteoarthritis Lancet 20 05, 3 65: 9 65- 973 50 ... spinaltropisetron-sensitive, non -5- HT3 receptor-mediated effect Mol Pharmacol 2004, 66:728-734 Graham GG, Scott KF: Mechanism of action of paracetamol Am J Ther 20 05, 12:46 -55 Brandt KD: The role of analgesics ... for the management of both OA and RA include the prevention or amelioration of joint damage, the prevention of loss of function, and the reduction of pain [8,9] In the absence of complete remission,...
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Báo cáo khoa học: " Integration of chemotherapy into current treatment strategies for brain metastases from solid tumors" potx
Ngày tải lên :
09/08/2014, 10:21
... [6] 25/ 25 49/49 236/311 73/136 106/ 157 62/118a 43/117b 137/208 164/269c 2 05/ 4-18 lesions eachd Surgery Surgery 20; 10–30 17 .5; 6 50 20; 12– 25 18; 15 22 17 .5; 15 22 16; 12– 25 Not given; 15 24 ... combinations of the keywords "radiotherapy or chemotherapy" and "brain metastases or cerebral metastases" In addition, the reference lists of all articles and the abstracts of the annual meeting 20 05 of ... transient and often limited to 3–6 months Median survival was 3–10 months The choice of chemotherapy regimen is often complicated by previous systemic treatment and takes into account the activity of...
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báo cáo khoa học: "R-CHOP versus R-CVP in the treatment of follicular lymphoma: a meta-analysis and critical appraisal of current literature" ppt
Ngày tải lên :
10/08/2014, 22:20
... with odds ratios of 5. 45 ( 95% CI: 2 .51 – 11.83) and 5. 54 ( 95% CI: 2.69 – 11.40), for the first and second analyses, respectively Discussion Data from all four trials were collected and the response ... 74; 45. 7% 41; 25. 3% 4;2 .5% 65; 40.1% 103; 63.6% 21; 13.0% I/II: 2; 1.2% III/IV: 160; 98.8% 39; 24.1% M: 176; 45. 7% F: 209; 54 .3% 123; 31.9% 20; 5. 2% 1 45; 37.7% 239; 62.1% 63; 16.4% I/II: 2; 0 .5% ... older, and were women On the con- R-CVP (N = 162) vs CVP (N = 159 ) PR (n; %) 22; 55 % 16; 40% OR (n; %) Criteria 38; 95% Table 44; 20% 170; 77% 214; 96% IWG[13] 35; 17% 150 ; 73% 1 85; 90% 12; 75% 2;...
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báo cáo khoa học: "Angiogenesis inhibitors in the treatment of prostate cancer" pdf
Ngày tải lên :
10/08/2014, 22:21
... II 15 mCRPC of 15 had PSA decline < 50 % No PSA decline > 50 % No objective responses Bevacizumab 15 mg/kg d2 Docetaxel 70 mg/m2 q3wk Estramustine 280 mg TID d1 -5 PhII 79 mCRPC PSA response > 50 % ... docetaxel-naïve PSA response > 50 % in 53 % of thalidomide group vs PSA response > 50 % in 37% of control group (p = 0.32) OS of 25. 9 mo in thalidomide group vs OS of 14.7 mo in control group (p ... for his comments and review of the manuscript Page 10 of 12 10 11 12 13 14 15 16 17 18 Author details Department of Internal Medicine, Henry Ford Hospital, CFP 55 9, 2799 West Grand Blvd, Detroit,...
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TREATMENT OF BIPOLAR DISORDER IN CHILDREN AND ADOLESCENTS - PART 5 ppsx
Ngày tải lên :
11/08/2014, 04:20
... only and child only and child only and child 10 11 12 13 Parent Parent Parent Parent Parent Parent only and child only and child only and child 14 Parent only 15 Parent and child 16 Parent and ... Archives of General Psychiatry, 58 , 51 0– 51 2 Biederman, J., Mick, E., Faraone, S V., Spencer, T., Wilens, T E., & Wozniak, J (2003) Current concepts in the validity, diagnosis and treatment of paediatric ... comparison of adolescent suicide victims with suicidal inpatients Archives of General Psychiatry, 45, 58 1 58 8 180 DIAGNOSIS AND TREATMENTS Butzlaff, R L., & Hooley, J M (1998) Expressed emotion and...
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Báo cáo y học: "P38 MAP kinase inhibitors as potential therapeutics for the treatment of joint degeneration and pain associated with osteoarthritis" ppsx
Ngày tải lên :
11/08/2014, 08:22
... CochranMantel-Haenszel test Results SB-20 358 0 and VX -7 45 are potent inhibitors of p38, TNFα and IL-1β in vitro The in vitro potencies of SB-20 358 0 and VX-7 45 for p38 and cytokine inhibition were evaluated ... iodoacetate model of cartilage degeneration Both SB-20 358 0 and VX-7 45 were potent inhibitors of p38 with IC50s of 136 ± 64 nM (mean ± S.D., n = 3) and 35 ± 14 nM (mean ± S.D., n = 8), at 50 μM ATP concentrations ... with IC50s 16 ± nM and 14 ± nM, (mean ± S.D., n = 3) for SB-20 358 0 and VX-7 45 and IL-1 was inhibited with IC50s of 20 ± nM and 15 ± nM (mean ± S.D., n = 3), respectively (Table 1) P38 inhibitors...
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SURGICAL OPTIONS FOR THE TREATMENT OF HEART FAILURE - PART 5 pot
Ngày tải lên :
11/08/2014, 15:20
... Cardiol 1997:30:7 25 Selection and Management of Potential Candidate for Cardiac Transplantation 89 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 Waagstein F, ... 1988;7: 258 90 55 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 Lynne Warner Stevenson Grattan MT, Moreno-Cabral CE, Stames VA, et al Eight year results of ... with 50 40 S I I 5 30 20 10 >1 1 -5 6-10 11^1? 18-34 35- 49 50 -64 > 65 Age Figure Age distribution of heart transplant recipients Registrv uf In! Soc for Heart & Lung Tmnsphtntation: 15" ' Official...
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Báo cáo y học: " Maintenance of response with atypical antipsychotics in the treatment of schizophrenia: a post-hoc analysis of 5 double-blind, randomized clinical trials" ppsx
Ngày tải lên :
11/08/2014, 16:23
... Olanzapine Quetiapine 171 15. 6 (4.3) 24 1 75 455 .8 ( 156 .3) Schz, Schzaff Outpatients Age 18 to 65 Score ≥ on at least 3, or ≥ on at least of the negative symptom items of the PANSS, and ≥ 60 (moderate ... sadness) of the MADRS 28 Schz Initial PANSS Total score of ≥ 75, a minimum score of ≥ on one of the PANSS positive, and a minimum score of on the CGI-S at both visits (screening) and (randomization), ... Loss of Response in 10% and 25% of Patients (days) 10% 25 % Treatment Used N Censored n (%) Olanzapine 166 138 (83) 56 Ziprasidone 123 87 (71) 35 96 P Value 008 Figure1–7 Total score of PANSS8...
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Current Issues of Water Management Part 5 doc
Ngày tải lên :
12/08/2014, 05:20
... 2,233,967. 75 3,689 ,54 9.00 -1, 455 ,58 1. 25 7 ,51 9,608.13 8 ,56 5,189.38 -1,0 45, 581. 25 16 ,52 4, 756 .81 18,420,338.06 -1,8 95, 581. 25 2 ,55 9 ,50 0.39 7,009 ,56 9.14 -4, 450 ,068. 75 Iwsc 1. 65 1.14 1.11 2.74 Table Values of ... [%] 750 ) 221940 81 .5 16.6 1.9 Total 1290232 78.3 13.1 8.6 Method of irrigation Flood ... levels of government at the national, provincial and local levels Integration of land and water management in the context of a developing country In terms of applying the concepts of IRM, INRM and...
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Báo cáo khoa học: "Efficacy of Targeted 5-day Combined Parenteral and Intramammary Treatment of Clinical Mastitis Caused by Penicillin-Susceptible or PenicillinResistant Staphylococcus aureus" pdf
Ngày tải lên :
12/08/2014, 15:20
... 41 86 39 15 24 91 23 68 13 71.7a 56 .1c 79.1d 33.3b 33.3 33.3 Total 166 104 62.7 Total5 controls3 % 75. 6 29.2 % n % 80 23 57 13 63.0e 56 .1 66.3 33.3f 53 .3g 20.8h 71 20 51 55 .9i 48.8 59 .3 17.9j ... parenteral and intramammary administration; duration of all treatments was days The efficacy of the treatment was assessed and weeks post -treatment for those treated with combined treatment and weeks ... parenterally at a dose of 7.0 mg amoxycillin and 1. 75 mg clavulanic acid per kg once a day for days combined with intramammaries containing 200 mg amoxycillin, 50 mg clavulanic 55 acid and 10 mg prednisolone...
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![Báo cáo khoa học: "Efficiency of 7.2% hypertonic saline hydroxyethyl starch 200/0.5 versus mannitol 15% in the treatment of increased intracranial pressure in neurosurgical patients – a randomized clinical trial [ISRCTN62699180]" pptx](https://media.store123doc.com/images/document/2014_08/14/medium_kZKnW9NZqy.jpg)
Báo cáo khoa học: "Efficiency of 7.2% hypertonic saline hydroxyethyl starch 200/0.5 versus mannitol 15% in the treatment of increased intracranial pressure in neurosurgical patients – a randomized clinical trial [ISRCTN62699180]" pptx
Ngày tải lên :
12/08/2014, 22:22
... Mannitol 15% 78 [58 – 95] 80 [58 –96] 80 [60– 95] 81 [58 –93] 79 [56 –96] 7.2% NaCl/HES 200/0 .5 84 [64–98] 84* [68–96] 84* [67–97] 85* [74–100] 84 [63–94] Mannitol 15% 84 [68–92] 85 [ 65 98] 83 [69–1 05] 81 ... episodes of increased ICP exceeding 20 mmHg requiring infusion of study medication (3 .5 treatments/patient) For 49 of these episodes (92 .5% ), infusion of mannitol was effective and reduced ICP to < 15 ... applications of mannitol, but a further application of hypertonic saline lead to a further ICP reduction [55 ,56 ] However, a direct vasodilatation of pial vessels [57 -59 ], the reduction of blood viscosity...
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Báo cáo khoa học: "Metabolic effects of phosphodiesterase III inhibitors: another reason to promote their use" pptx
Ngày tải lên :
13/08/2014, 03:21
... shock Crit Care Med 2001, 29: 151 9- 152 5 Parsonage WA, Hetmanski D, Cowley AJ: Beneficial haemodynamic effects of insulin in chronic heart failure Heart 2001, 85: 508 -51 3 Trof RJ, Di Maggio F, Leemreis ... severe sepsis and cardiogenic shock Crit Care Med 20 05, 33:22 352 240 Okuda M: A multidisciplinary overview of cardiogenic shock Shock 2006, 25: 557 -57 0 Orime Y, Shiono M, Hata H, Yagi S, Tsukamoto ... Maggio F, Leemreis J, Groeneveld AB: Biomarkers of acute renal injury and renal failure Shock 2006, 26:2 45- 253 Chiu YJ, Hu SH, Reid IA: Inhibition of phosphodiesterase III with milrinone increases...
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