crunching sound on chest examination is found with which condition
Báo cáo y học: "The protective effect of licofelone on experimental osteoarthritis is correlated with the downregulation of gene expression and protein synthesis of several major cartilage catabolic factors: MMP-13, cathepsin K and aggrecanase" docx
Ngày tải lên :
09/08/2014, 06:23
... that demonstrated great variability in the response of chondrocytes to the synthesis of ADAMTS-5 upon stimulation by cytokines and growth factors under actual conditions [15] A regulation of the ... exact mechanism(s) by which licofelone reduces the mRNA expression level of cathepsin K is not fully understood; it is under exploration Because the synthesis of cathepsin K has been demonstrated ... resorption in the early phase of experimental dog osteoarthritis by licofelone is associated with a reduction in the synthesis of MMP-13 and cathepsin K Bone 2004, 34:527-538 19 Fernandes JC, Caron...
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Báo cáo khoa học: A distinct sequence in the adenine nucleotide translocase from Artemia franciscana embryos is associated with insensitivity to bongkrekate and atypical effects of adenine nucleotides on Ca2+ uptake and sequestration pdf
Ngày tải lên :
29/03/2014, 00:20
... we concluded that the ANT of our mitochondrial preparations of A franciscana embryos is fully functional ANT of A franciscana is refractory to inhibition by BKA As mentioned above, BKA was without ... operation In contrast, addition of BKA (50 lm, trace d) failed to inhibit ANT operation as compared with the control (5 mm NH4OH, which is the vehicle of BKA, trace c) With the same BKA stocks, this ... is different from Artemia ANT is colored yellow, and the corresponding part of Artemia ANT is colored 830 magenta In region a, this corresponds to His209– Gln218 in bovine ANT, which corresponds...
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Báo cáo y học: "Chronic development of collagen-induced arthritis is associated with arthritogenic antibodies against specific epitopes on type II collagen" ppt
Ngày tải lên :
09/08/2014, 07:20
... response shifting along the chronic disease course in each individual mouse is not only genetically controlled but also a stochastic process An explanation could be that the selection of which ... Gustav V 80 years foundation, the Kock and Österlund foundations, the Swedish Association against Rheumatism, the Swedish Science Research Council and the Strategic Science Foundation References ... directed against distinct epitopes on the triple-helical part of CII correlate with chronic arthritis and induce arthritis relapses Arthritis epitopesdevelopment in arthritis and responses to CII/CII-specific...
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Báo cáo y học: " Sitagliptin is effective and safe as add-on to insulin in patients with absolute insulin deficiency: a case series" potx
Ngày tải lên :
11/08/2014, 00:23
... to suppression of glucagon levels The mechanism by which GLP-1 suppresses glucagon secretion is far from being elucidated, and furthermore it is unclear whether endogenous insulin is a required ... for this effect On the basis of the data from the present case report and others [8,9], one might be able to envisage that the effect of GLP-1 on glucagon secretion would not be dependent on endogenous ... function was observed in association with this drug Although the limit of detection of C-peptide in the assay used in this report was 0.1 ng/ml (measured at Mitsubishi Kagaku, Tokyo, Japan), one...
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Báo cáo y học: "Development of bone marrow lesions is associated with adverse effects on knee cartilage while resolution is associated with improvement - a potential target for prevention of knee osteoarthritis: a longitudinal study" pdf
Ngày tải lên :
12/08/2014, 11:22
... of bone marrow lesions is associated with adverse effects on knee cartilage while resolution is associated with improvement - a potential target for prevention of knee osteoarthritis: a longitudinal ... 2000, 215:835-840 Felson DT, Chaisson CE, Hill CL, Totterman SMS, Gale E, Skinner KM, Kazis L, Gale DR: The association of bone marrow lesions with pain in knee osteoarthritis Ann Intern Med 2001, ... patients with osteoarthritis: associations with clinical features Eur Radiol 2007, 17:3073-3078 11 Boegard T, Rudling O, Petersson IF, Jonnson K: Magnetic resonance imaging of the knee in chronic...
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Báo cáo y học: "Arthritis is associated with T-cell-induced upregulation of Toll-like receptor 3 on synovial fibroblasts" docx
Ngày tải lên :
12/08/2014, 17:22
... the T-cell conditioned medium instead of T cells to be incubated with the FLSs and found that FLSs with pristane-primed T-cell conditioned medium showed strong induction of TLR3 expression and increased ... pristane-primed, T-cell-conditioned medium Rat FLSs were incubated with pristane-primed T-cell- or control T-cell-conditioned medium for 24 hours, and (A) TLR3 and (B) functional gene expression in FLSs were ... treated with poly(I:C) compared with rats treated with poly(I:C) alone exhibited more persistent inflammation and joint destruction, which might be due to the upregulation of TLR3 expression in...
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Báo cáo y học: "Triggering receptor expressed on myeloid cells-1 expression on monocytes is associated with inflammation but not with infection in acute pancreatitis" pdf
Ngày tải lên :
13/08/2014, 16:20
... are at high risk of infection Ho and colleagues found that HLA-DR expression on less than 52.3% of monocytes on the 10th day after admission correlated with late mortality in patients with severe ... infection Key messages • Increased TREM-1 expression on blood monocytes is an indicator of inflammation but not of infection in patients with AP • Low HLA-DR expression and high IL-6 concentration ... et al Conclusions Increased TREM-1 expression was associated with the presence of inflammation but not infection in AP In patients with AP, low HLA-DR expression and high IL-6 concentration could...
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Báo cáo y học: " Is there a protective effect of normal to high intellectual function on mental health in children with chronic illness" docx
Ngày tải lên :
13/08/2014, 18:21
... children with CI The estimated risk of psychiatric disorder in this case-control sample of children with CI is in accordance with the twofold increased risk of mental health problems in children with ... as four factor scores [16] WISC-III is a widely used test of intellectual function, with strong criterion validity [24] In the present study, the WISC-III was administered and scored by well-trained ... functioning Scores above 70 indicate normal function The CGAS is considered a valid and reliable tool for rating a child’s general level of functioning on a health-illness continuum, and is recommended...
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Mild cognitive impairment is associated with falls among older adults findings from the irish longitudinal study on ageing (TILDA)
Ngày tải lên :
25/08/2016, 22:05
... State MA Examination (MMSE) score≥14; and no limitations in activities of daily living (ADL) Multivariable poisson and logistic regression analyses were conducted to D assess the association between ... (including myocardial infarction and coronary thrombosis), stroke (cerebral vascular disease), or Parkinson's disease Heart disease referred to having at least one of: angina, congestive heart failure, ... categorical and continuous variables SC R respectively Poisson and logistic regression analyses were done with number of falls and presence of non-accidental falls in the past 12 months as the outcome...
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Báo cáo y học: "Genetic polymorphism of p53, but not GSTP1, is association with susceptibility to esophageal cancer risk – A Meta-Analysis"
Ngày tải lên :
25/10/2012, 11:40
... indicated association For each study, the OR is plotted on a logarithmic scale against the precision (the reciprocal of the SE) Discussion The GSTP1 gene, which encodes the GST π isoenzyme, is the most ... selected study characteristics are listed in Table and Table All studies indicated that the distributions of two polymorphism’s genotypes in the controls were both consistent with Hardy-Weinberg ... substrates.[37-39] However, our analysis results showed there was no significant relations between GSTP1 Ile105Val polymorphism and esophageal cancer, but this conclusion was consistent with Hiyama T et al’ s...
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Báo cáo y học: " A Novel Variable Number of Tandem Repeat of the Natriuretic Peptide Precursor B gene’s 5’-Flanking Region is Associated with Essential Hypertension among Japanese Females"
Ngày tải lên :
26/10/2012, 10:04
... a two-sided Fisher’s exact test Multiple logistic regression analyses were done to assess the contribution of confounders (gender, BMI) [17] A value of P < 0.05 was considered statistically significant ... transcriptional initiation site) (GenBank accession number AB265677) This VNTR polymorphism is a tandem repeat of the 4-nucleotide sequence TTTC (Fig 1A) There were alleles of this VNTR polymorphism, ... with a deletion of this gene develop disorders that resemble the symptoms of subjects with a deleted allele in the 5’-untranslated region of NPRA We previously isolated a missense mutation of the...
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Tài liệu Sound On-Board làm việc như thế nào? – Phần 1 ppt
Ngày tải lên :
23/01/2014, 06:20
... ba: với kết nối digital, bạn cần dùng sợi cáp kết nối từ máy tính tới Home Theater Loa Digital Trong với kết nối Analog bạn cần cáp cho cặp loa (trên hệ thống Loa 5.1, bạn cần ba loại cáp) Hạn ... 5.1 đồng nghĩa 6, 7.1 có nghĩa Cũng có cách khác đề cập tới vấn đề Với âm kênh (có nghĩa 7.1) Trong này, bạn thấy có lỗ cắm hình thứ thể theo màu sắc sau : • • • • • • Màu hồng: Micro vô Xanh ... bạn thấy có lỗ cắm màu Hồng, Xanh lam Xanh Các mainboard có kênh âm thanh, lỗ màu Đen màu Cam Trong trường hợp lỗ màu Xanh lam dùng cho “Line In” “Loa phía sau”, lỗ màu Hồng dùng cho “Mic In”...
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Tài liệu Báo cáo khoa học: The splicing factor ASF/SF2 is associated with TIA-1-related/ TIA-1-containing ribonucleoproteic complexes and contributes to post-transcriptional repression of gene expression doc
Ngày tải lên :
16/02/2014, 15:20
... existence of ASF ⁄ SF2-TIA complexes is conditioned by the tissue distribution of TIA protein [46], which is clearly more restricted compared to ASF ⁄ SF2 [48] ASF ⁄ SF2 migration into SGs strongly ... normal conditions However, upon oxidative stress, only ASF ⁄ SF2 protein migrated in TIARpositive cytoplasmic foci (Fig 2B) ASF/SF2 is associated with TIAR and TIA-1 protein complexes and is a bona ... nuclear fraction of ASF ⁄ SF2 is phosphorylated [31,32] and ASF ⁄ SF2 nuclear export is conditioned by a dephosphorylation process [33,34], we analyzed the sub-cellular distribution of a phosphomimetic...
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Tài liệu Báo cáo khoa học: Phosphorylation of cyclin dependent kinase 4 on tyrosine 17 is mediated by Src family kinases pptx
Ngày tải lên :
18/02/2014, 18:20
... kinases is completely novel and it is interesting to note how this fits in with the previously published data CDK4 phosphorylation on Y17 is considered to restrain cell cycle progression in UV ... nuclear fractionation; however, the potential existence of nuclear C-YES warrants further investigation The study then demonstrated that C-YES phosphorylates CDK4 on Y17 when expressed along with CDK4 ... kinase LYN is already known to phosphorylate CDK1 [30,31] and CDK2 [32] on Y15 in response to DNA damage, and it is plausible that LYN may also phosphorylate CDK4 on Y17 in this context It is clear,...
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Tài liệu Báo cáo khoa học: Cell surface nucleolin on developing muscle is a potential ligand for the axonal receptor protein tyrosine phosphatase-r ppt
Ngày tải lên :
19/02/2014, 05:20
... and incubated with varying concentrations of conditioned media containing FN3d–AP The data revealed significant binding of PTPr to nucleolin above that of the BSA control (Fig 3), demonstrating that ... secretion signal and it is therefore not known how it reaches the cell surface The clustering of nucleolin on cell surfaces is nonetheless dependent on an intact actin cytoskeleton, to which it ... Harrington RJ, Hudson ML, Williams L, Kenyon CJ, Chisholm AD & Jin Y (2005) The two isoforms of the Caenorhabditis elegans leukocyte-common antigen related receptor tyrosine phosphatase PTP-3 function...
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Tài liệu Báo cáo khoa học: Down-regulation of heme oxygenase-2 is associated with the increased expression of heme oxygenase-1 in human cell lines docx
Ngày tải lên :
19/02/2014, 05:20
... causes late-onset induction of HO-1 mRNA In this context, we have reported that maximum induction of HO-1 mRNA expression was detected within h by treatment with cadmium in HeLa cells, which is due ... Development for Common Diseases’ from the Ministry of Education, Science, Sports, and Culture of Japan References Taketani S (2005) Aquisition, mobilization and utilization of cellular iron and heme: ... did not change the concentrations of GAPDH mRNA and b-actin (Fig 4C,D) Consistent with HO-1 mRNA expression, expression of HO-1 protein was also induced by the treatment with HO-2 siRNA in HepG2...
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Tài liệu Báo cáo khoa học: Stimulation of poly(A) synthesis by Escherichia coli poly(A)polymerase I is correlated with Hfq binding to poly(A) tails ppt
Ngày tải lên :
19/02/2014, 16:20
... These data are consistent with the idea that Hfq forms a complex with RNA which, in this case, has an inhibitory effect on binding of poly(A) by PNPase In contrast, an interaction between Hfq ... Hfq–poly(A) complex, which facilitates elongation of the RNA by PAP I, prevents its recognition by PNPase which inhibits both degradation and elongation of the RNA by this latter enzyme These ... affect synthesis of poly(C) tails by PAP I Hfq (160 nm) does not inhibit poly(C) synthesis but at this Hfq concentration and at higher concentrations (data not shown) degradation of the RNA substrate...
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Báo cáo khoa học: Muramyl-dipeptide-induced mitochondrial proton leak in macrophages is associated with upregulation of uncoupling protein 2 and the production of reactive oxygen and reactive nitrogen species docx
Ngày tải lên :
05/03/2014, 23:20
... oxygen consumption rates after addition of various substrates and inhibitors The mitochondrial respiratory function is conventionally separated into different states State is the oxygen consumption ... support is the function of UCP2 to attenuate mitochondrial production of free radicals and to protect against oxidative damage [10,11] This is mainly based on the activation of mitochondrial proton ... oxidation State is defined as the phosphorylation state and is dependent on the oxygen consumption in the presence of ADP, thus reflecting the mitochondrial respiration coupled to ATP production State...
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Báo cáo khoa học: Cellular refractoriness to the heat-stable enterotoxin peptide is associated with alterations in levels of the differentially glycosylated forms of guanylyl cyclase C pdf
Ngày tải lên :
08/03/2014, 08:20
... phosphorylation in the receptor on serine residues, there is no alteration in the phosphorylation status on ligand addition (unpublished observations) Given the contrasting rates of desensitization observed ... three times with immunoprecipitation buffer containing Triton X-100 and twice with immunoprecipitation buffer without Triton X-100 and proteins were resolved on 7.5% SDS, transferred onto poly(vinylidene ... occur on long-term treatment of cells with ST As the 130 kDa form of GC-C is still on the surface after prolonged ST treatment, it is not clear at this time whether the 130 kDa form alone is recycled,...
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