... In order to truly rescue brain tissue and function, one may have to rescue all the complex signals and interactions between a network of multiple cell types, including neurons, astrocytes and ... astrocytes and endothelium alters tight junction homeostasis and leads to BBB disruption Perturbations in neuronal– glial signaling lead to loss of proper neurotransmitter dynamics And loss of ... angiogenesis may improve cerebral perfusion and function as part of a network repair The spatial and temporal dynamics of post-stroke angiogenesis are complex and remain incompletely characterized...
Ngày tải lên: 18/02/2014, 11:20
... disorders back in and developed for the treatment of shoulder, elbow and ankle disorders in the s, has made direct visualization of joint movement and intra-articular structures possible, and ... ndings, both basic and applied, in order to provide the best possible recommendations and treatments for patients and for the population in general There is a tradition in Scandinavia for an interaction ... few randomized studies in sports medicine and especially within traumatology This is often due to a high demand for treatment to ensure fast recovery and return to sports participation, and it...
Ngày tải lên: 15/03/2014, 09:20
Novel Insights on Chronic Kidney Disease, Acute Kidney Injury and Polycystic Kidney Disease Edited by Soundarapandian Vijayakumar pdf
... its myriad causes and manifestations, outline current standards of diagnosis and care, and discuss experimental animal models with relevance in unraveling clinical conundrums and molecular mechanisms ... sponsorships and speakers’ honoraria from Amgen, Roche and Janssen-Cilag He is a recipient of consultancy fees from Sandoz and is a co-investigator on industry-sponsored research by Amgen, Roche and Janssen-Cilag ... of the abdomen and pelvis (D) are grouped into perfusion, parenchymal, and excretion phases Ten milligrams of furosemide were administered 20 minutes after tracer injection With injection of the...
Ngày tải lên: 23/03/2014, 17:20
Sport, Professionalism and Pain: Ethnographies of injury and risk doc
... body and social theory 53 Pain and the body 65 Summary 69 vi PART II Pain, injury and the culture of risk 70 71 The concept of pain 72 Medical practice and the nature of pain 77 Positive pain and ... Sport in the School of Sport and Leisure at the University of Gloucestershire Sport, Professionalism and Pain Ethnographies of injury and risk P.David Howe LONDON AND NEW YORK First published ... Sport, Professionalism and Pain: Ethnographies of injury and risk Sport, Professionalism and Pain considers these and other pertinent concerns as it questions whether,...
Ngày tải lên: 30/03/2014, 02:20
báo cáo hóa học: " The Dutch version of the knee injury and osteoarthritis outcome score: A validation study" pdf
... questionnaire, SF-36 and VAS for pain The correlation between KOOS Pain and SF-36 BP, between KOOS Pain and SF-36 PF, KOOS (all subscales) and VAS for Pain and KOOS ADL and SF-36 PF should be ... MMF, CBT and MR designed the study IBG wrote the manuscript and guided data collection, analyses and interpretation MMF assisted with writing the manuscript, data collection, analyses and interpretation ... Bierma, L Blokker and G Hagevi for translating and re-translating the Dutch KOOS questionnaire and, of course, all the patients who participated in this study References VanderZee KI, Sanderman R,...
Ngày tải lên: 18/06/2014, 22:20
báo cáo hóa học: " Interleukin-1alpha expression precedes IL-1beta after ischemic brain injury and is localised to areas of focal neuronal loss and penumbral tissues" pdf
... immune studies and analysis KJK contributed to the design and execution of the surgical studies GLC contributed experimentally DB contributed to design and analysis of the study and wrote the ... design and analysis of the study and wrote the manuscript All authors read and approved the final manuscript Acknowledgements This work was funded by the Wellcome Trust (DB, NML, GLC), and by ... IL-1α and IL-1β, are considered the major effectors of injury, and inhibiting their signalling with the IL-1 receptor antagonist (IL-1Ra) is protective in experimental models of stroke [1], and...
Ngày tải lên: 19/06/2014, 22:20
Health and Quality of Life Outcomes BioMed Central Research Open Access Knee injury and pptx
... in total hip replacement [31] ER and STL designed the study and coordinated the data collection ER analyzed the data and drafted the manuscript Both authors read and approved the final manuscript ... HP, Ekdahl C and Lohmander LS Knee injury and Osteoarthritis Outcome Score (KOOS) – validation of a Swedish version Scand J Med Sci Sports 1998, 8:439-48 Roos EM, Klassbo M and Lohmander LS WOMAC ... Orthop 1985, 43-9 Ware JE Jr and Sherbourne CD The MOS 36-item short-form health survey (SF-36) I Conceptual framework and item selection Med Care 1992, 30:473-83 Bland JM and Altman DG Statistical...
Ngày tải lên: 20/06/2014, 15:20
báo cáo hóa học: " A cohort study of short-term functional outcomes following injury: the role of pre-injury sociodemographic and health characteristics, injury and injury-related healthcare" pot
... associations between lower extremity and spine and back injuries and mobility problems, and injuries to the head and neck and cognitive Langley et al Health and Quality of Life Outcomes 2011, 9:68 ... Zealand - Auckland, Manukau City, Gisborne, Otago, and Southland Each month, potential participants were selected from new ACC claimants ACC then sent, on our behalf, a letter of invitation and ... potential pre-injury and injury-related explanatory variables [2] We grouped our explanatory variables into: preinjury socio-demographic, pre-injury health and disability, and injury and post-injury...
Ngày tải lên: 20/06/2014, 15:20
INJURY AND SKELETAL BIOMECHANICS docx
... focus on biped and quadruped walking as motion patterns and report the suitable motion selection between biped and quadruped walk considering the walking stability and efficiency Motion and recognition ... platform Kistler and the interaction forces between feet and ground were analysed in three directions (vertical, lateral, and anteroposterioric) The data of the groups were compared and results were ... IA’ and the defender IB’ For this purpose, their central moments of inertia ICA and ICB, as well as the distances dA and dB from their centres of mass mA and mB (Fig 2), must be 40 Injury and...
Ngày tải lên: 28/06/2014, 10:20
Báo cáo lâm nghiệp: " The role of glutamine synthetase, glutamate synthase and glutamate dehydrogenase in ammonia assimilation by the mycorrhizal fungus Pisolithus tinctorius" ppt
... glutamate and glutamine were 0.38 pmol/g and 0.19 !mol/g fresh weight, respectively, in the N-starved mycelia Rapid ammonia assimilation was shown in the controls by marked increase in the and glutamine ... nitrogenous metabolites Discussion and Conclusions Enzyme assays showed that the ECM fungus P tinctorius was capable of ammonia assimilation by both GS and GDH activities, and that both pathways were ... glutamine by the activity of GS, and transferred to glutamate-amino by glutamate synthase activity Inhibition of GS and glutamate synthase blocked the synthesis of glutamine and glutamate, respectively...
Ngày tải lên: 09/08/2014, 04:20
Traumatic brain injury and the effects of diazepam, diltiazem, and MK-801 on GABA-A receptor subunit expression in rat hippocampus ppt
... Institutional Animal Care and Use Committee at Creighton University, where the primary and secondary authors were both affiliated at the time of data collection Surgical Preparation and Injury Animals ... supported Both α1 and γ2 subunit expression increased acutely after injury, but were significantly decreased by 24 h, while α3 and β3 showed time-specific transient changes and α2 and α5 subunits ... TBI, while diltiazem and DZ treatments had nearly identical effects, normalizing γ2 and altering α1 and α3 expression DZ also significantly increased α2 expression in both sham and injured animals...
Ngày tải lên: 10/08/2014, 05:21
Báo cáo y học: "Traumatic vertebral artery dissection in an adult with brachial plexus injury and cervical spinal fracture" pptx
... Elizabeth C, Ouellette Eileen M, Buonanno Ferdinando: Vertebral Artery Dissection: Issues in Diagnosis and Management Pediatric Neurology 1996, 14(3):255-258 Mandila Christina G, Koukoulitsios Georgios ... Karampelas Ioannis, Karydas Georgios, Karabinis Andreas: Unilateral and bilateral vertebral artery dissection following motor vehicle injury – two cases and a mini-review International Journal of ... radiographs of the neck (Antero-posterior, lateral, and open-mouth) showed loss of cervical lordosis, fracture of the right transverse process of C6 and increased pre-vertebral soft tissue shadow...
Ngày tải lên: 10/08/2014, 10:20
Báo cáo y học: "Cholestatic jaundice, acute kidney injury and acute pancreatitis secondary to the recreational use of methandrostenolone: a case report" potx
... injury and pancreatitis Conclusion AAS use and misuse is being seen in an expanding population of patients because they are readily available and often perceived as safe The side effects and risks ... Authors’ contributions GR and AC were major contributors in writing the manuscript EY and PK analyzed and interpreted the patient data regarding the patient’s presentation and provided the clinical ... had intermittent and occasionally heavy alcohol consumption on weekends He had also been taking methandrostenolone: 10 mg orally twice a day, five days a week for three weeks and then three times...
Ngày tải lên: 11/08/2014, 00:23
báo cáo khoa học: " The evolution of the Global Burden of Disease framework for disease, injury and risk factor quantification: developing the evidence base for national, regional and global public health action" pps
... registration and certification of all deaths is less common, due to the cost of establishing and maintaining such a system, and often the mortality data collected are incomplete and of poor quality ... measures of population health, the development of methods and approaches to estimate missing data and to assess the reliability of data, and the use of a common metric to summarise disease burden ... including China and much of Latin America, and "high mortality developing" including Sub-Saharan Africa, and many countries in Western and Southern Asia, including India, Bangladesh and Myanmar As...
Ngày tải lên: 11/08/2014, 18:20
Báo cáo y học: " The first description of severe anemia associated with acute kidney injury and adult minimal change disease: a case report" ppsx
... clinical information and critically reviewed the content of the paper EF interpreted patient data and the literature and critically reviewed the content of the paper All authors read and approved the ... changes in hematocrit (A) and creatinine levels (B) of the patient Therapy scheme and resultant changes in hematocrit (A) and creatinine levels (B) of the patient Hemodialysis and erythropoietin treatments ... of corticosteroid therapy and months following presentation there was no sign of recurrence Thus, this case is unusual in both its clinical and pathologic features and, to our knowledge, is the...
Ngày tải lên: 11/08/2014, 19:21
báo cáo khoa học: " Differential patterns of reactive oxygen species and antioxidative mechanisms during atrazine injury and sucrose-induced tolerance in Arabidopsis thaliana plantlets" ppsx
... CS, MB, IC and GG conceived the study and designed experiments FR, MB and GG performed the experiments FR, CS, MB, IC and GG carried out analysis and interpretation of experimental data including ... measured at 663 nm, 646 nm and 470 nm Levels of chlorophyll and total carotenoids (xanthophylls and carotenes) were determined from the equations given by Lichtenthaler and Wellburn [72] Measurements ... hours to the different control and treatment media described above (M, S, MA and SA) Plantlets, prior to the transfer and at the end of the treatment, were immersed and infiltrated in the dark under...
Ngày tải lên: 12/08/2014, 03:20
Báo cáo y học: " The role of γδ T cells in airway epithelial injury and bronchial responsiveness after chlorine gas exposure in mice" pps
... also at 1, 3, and days after exposure There were no baseline differences in Rrs and Ers between wild type and knockout mice and between sham-exposed and Cl2 exposed groups (Figure 4A and 4B) Wild ... based on the standard curves established for each growth factor and a housekeeping gene Briefly, PCR products were extracted from agarose gel and purified with GFX PCR DNA and Gel Band Purification ... composition of bronchoalveolar lavage Data for control and chlorine exposed animals that were sacrificed 1, and days after chlorine are shown Both γδ T cell deficient mice and wild type animals are demonstrated...
Ngày tải lên: 12/08/2014, 15:20
Báo cáo y học: "Effects of short-term glucocorticoid treatment on changes in cartilage matrix degradation and chondrocyte gene expression induced by mechanical injury and inflammatory cytokines" doc
... analyzed the data, conceived of and designed the studies, confirmed data analysis and wrote the manuscript CE and AJG conceived of and designed the studies, confirmed data analysis and wrote the ... oxide synthase (iNOS) mRNA and protein levels, and the role of glucocorticoid receptors A disintegrin and metalloproteinase with thrombospondin motifs-4,-5 (ADAMTS-4 and -5) are the primary aggrecanases ... transcription, effects of DEX on iNOS mRNA and protein levels, and inhibition of glucocorticoid receptors and proprotein convertases Bovine cartilage harvest and culture Cartilage disks were harvested...
Ngày tải lên: 12/08/2014, 18:20