comparison of the face map sizes

... underscoring the importance of the interactions between the Tyr OH and the side chains of Asn174 and Asp148 in TEV protease (Fig 4A) The importance of these interactions is further supported by the results ... effects of the mutations Hence, the results are consistent with the predicted role for these residues (based on crystal structure) in the interaction with substrate The loss of activity of the mutants ... Mutational analysis of TEV protease cleavage sites established that the specificity of the enzyme is restricted to the P6–P1¢ positions of the substrate [7,13] The crystal structure of catalytically...

Ngày tải lên: 19/02/2014, 16:20

... hand, and on the other by the attitude of the speaker towards the message and the addressee "Thus into the domain of the organization of utterance pertains all that is connected with the processual ... basic hypotheses, the second of which can conveniently be elaborated in terms of Ong's list of the characteristics of an orally-based language The two hypotheses and their respective sub-hypotheses ... aspect of utterance (in contrast to the abstract and static character of the other two levels), that is to say, the dynamism of the relations between the meanings of individual lexical items in the...

Ngày tải lên: 24/02/2014, 18:20

... Senior Lecturer of Anesthesia and Director of the Obstetric Anesthesia Unit at Shaarei Zedek Medical Center He is the current Chair of the Israel Association of Obstetric Anesthesia His main ... experience of personnel Accordingly, the OAAI is not a measure of the total activity of the obstetric anesthesia services Based on these limitations, it is important to appreciate that although the ... for the data presented in this study and will attempt to identify an ideal obstetric anesthesia staffing number based on the OAAI In summary, the use of the OAAI may facilitate a comparison of the...

Ngày tải lên: 05/03/2014, 15:20

... measure of the rate of oxidation of oxyHb RESULTS The effect of pH on the auto-oxidation of cross-linked Hb was studied The rate of decrease of the concentration of oxyHb increased as the pH was ... in the absence and presence of EDTA, on the oxidation of Hb A0 The mean ± SD of three independent experiments is shown Other conditions as in Fig Our studies of the effect of the structure of the ... the LPS of rough E coli (Fig 1) The effect of the LPSs of smooth and rough S minnesota on the oxidation rate of Hb A0 was compared (Fig 5) In Fig Comparison of the effects of the LPSs of rough...

Ngày tải lên: 08/03/2014, 10:20

Ngày tải lên: 16/03/2014, 03:20

... due to the proximity of the negative charge of the side chain of Glu706 from the neighboring subunit The mutation of these residues might interfere with the oligomerization required for the proteolytic ... Successful determination of the crystal structure of the proteolytic domain of E coli Lon [30] allowed us to explain the loss of proteolytic activity of the mutants at these sites [25] These three residues ... analysis of the amino acid sequences of the majority of the currently known Lon proteases The results of site-directed mutagenesis of E coli Lon protease and insights from the crystal structure of...

Ngày tải lên: 16/03/2014, 18:20

Ngày tải lên: 18/03/2014, 15:22

... above the capitals At the uppermost section of the entablature there is another cornice that outlines the roof of the entire building (picture 16) The main component of the façade is flanked by the ... the end of the exhibition, find himself on the ground floor, near the exit By doing this, the viewer is made to experience the entire building, from the top ramp, to the bottom and perceive the ... staircase is a set of parallel columns (picture 21) Just above the start of the staircase is a grand statue of Perseus with the Head of Medusa Unlike the Guggenheim museum, the Met offers a more conventional...

Ngày tải lên: 21/03/2014, 22:00

... into the active site of the human DPP-IV; 3, docked into the active site of the crystalline structure of PepX from L lactis; and 4, docked into the active site of the modeled structure of PepX ... group of the ligand and the NH2 of Asn470 (equivalent to Asn710 in DPP-IV) Another potential bond can be proposed between the OH atom of Tyr380 and the carbonyl group of the ligand Finally, the ... us to model the docking of the inhibitor into the PepX active site using the Lamarckian genetic algorithm of autodock 3.0 [26] We started from the reference of the crystal structure of DPP-IV complexed...

Ngày tải lên: 23/03/2014, 13:20

... expenditures would have the effect of breaching the 60% rule and would have to be financed either on the revenue or the expenditure side of the budget Since the bulk of the increase in government ... in the share of the over 65s in the populations of the EU15, US and Japan will inevitably occur due to the fact that the post-war baby-boom generations in the latter areas will be reaching the ... on the basis of an examination of the consequences of World War I and the subsequent low birth rates of the 1920s, that the French population would only be 35 million in 1980 when in fact the...

Ngày tải lên: 23/03/2014, 21:20

... Overview 1.2 Statement of the results 1.2.1 Almost-harmonic map results 1.2.2 Heat flow results 1.3 Heuristics of the proof of Theorem 1.2 Almost-harmonic maps — the proof of Theorem 1.2 2.1 Basic ... Control of e∂ ¯ 2.5.2 Analysis of neighbourhoods of antiholomorphic bubbles 2.5.3 Neck surgery and energy quantization 2.5.4 Assembly of the proof of Theorem 1.2 Heat flow — the proof of Theorem ... smooth maps S → S of degree k onto the space of rational maps of degree k, which is known to be impossible Indeed, we can think of the bubbling of the flow as measuring the discrepancy between the...

Ngày tải lên: 28/03/2014, 22:20

... color, the more exposed the residue) of the disks drawn behind some of the residues to denote the difference in their solvent exposure as a result of the presence of the ligand; the ligand solvent ... molecule B The receptor exposure is shown by the size and intensity (the darker the color, the more exposed the residue) of the disks drawn behind some of the residues to denote the difference in their ... Closer view (from the bottom) of the protein–ligand interactions and the surface of the binding site in the upper binding site The Gaussian contact surface is presented with the following color...

Ngày tải lên: 29/03/2014, 22:21

... pre-MBA income will be one of the determinants of his/her incremental income The other, the post-MBA income, is a function of the school, the candidate, and the state of the economy (GDP growth ... rate of return by comparing the costs of the degree (the initial investment) with the subsequent income (cash-flows) over the individual’s work life (the life of the project) Literature Review The ... degree is the additional salary that results from the degree, while the cost of the investment is the foregone income and associated tuition and fees The internal rate of return (IRR) on the MBA...

Ngày tải lên: 31/03/2014, 01:20

... increases the slope in the transition region of the unfolding curve for apo¯avodoxin but it has no effect on the slope of the curve for ¯avodoxin Furthermore, the slope of the curve for the holoprotein ... plots of the logarithm of the equilibrium constant (Kapp) for the unfolding of apo¯avodoxin calculated at 2.94 M (j) and 3.43 M (d) urea vs the logarithm of the mean activity of NaCl (ln a‹) the ... on the ionic composition of the solution The change in protein ¯uorescence as a function of the concentration of urea is consistent with a two-state model of unfolding, as are the kinetics of the...

Ngày tải lên: 31/03/2014, 15:20

... the back of the animals The split human keratome biopsies were then grafted onto the back of the animals The grafts were protected by a bandage during the following two weeks All the transplantation ... day 22 and the biomarkers were therefore only scored at the end of the study Considering the marked vehicle effect of the ointment vehicle observed on clinical score, it is likely that the biomarkers ... [15-17] However, these studies compared the biomarker profiles before and after treatment with the calcipotriol ointment and they did not assess the effects of the vehicle on the biomarker responses...

Ngày tải lên: 18/06/2014, 15:20

... information about wider effects of oral health on daily living The main advantage of generic measures is that they allow comparison of various domains of quality of life for the condition being studied, ... treatment These findings differed according to the indicator used to assess the impacts of oral conditions on participants' quality of life (the overall score or the prevalence of oral impacts) or the ... adolescent reported an impact on any of the performances, the frequency of the impact (scale from to 3) and the severity of its effect on daily life (scale from Page of (page number not for citation...

Ngày tải lên: 18/06/2014, 19:20

... asked whether they had experienced any of them within the last months Then, the single interviewer asked about difficulties in daily life caused by the problems that they marked on the list The impacts ... than the current face- to -face interview and would further facilitate the applicability of the instrument in both clinical practice and population epidemiological survey settings Therefore, the ... reliability of each mode of administration, inter-item correlations among the performances scores were calculated as correlation matrices Then, the comparison of the 28 inter-item correlations between the...

Ngày tải lên: 18/06/2014, 22:20

... acute version of the SF-36) for the SF-6D The third difference is that the scoring range of the EQ-5D is twice that of the SF-6D The location of the baseline median scores in the scoring range ... Figure Comparison of maximal theoretical contribution to the utility score Comparison of maxim al theoretical contribution to the utility score Domains measuring the same area of health have similar ... between the median values and the limits of agreement in the BlandAltman plot exceed the minimal clinically important difference of both SF-6D and EQ-5D [20,21] The lack of agreement is further...

Ngày tải lên: 20/06/2014, 15:20

... 1: The percentage of UK and US respondents endorsing some impact of their muscle disease on each of the life domains Figure The percentage of the UK and the US samples endorsing the direction of ... (extent of impact, importance of impact and overall impact) for each of the life domains and the results of the significance tests between the UK and US samples The overall importance score of all the ... weakness of the skeletal muscle such as to cause varying degrees of disability The individual muscle diseases differ in their age of onset, their rate of progression and their pattern of weakness...

Ngày tải lên: 20/06/2014, 15:20

... that is, the study of derivatives of the perturbation function On the other hand, by stability we mean the qualitative analysis, that is, the study of various continuity properties of the perturbation ... as the feasible set map In the vector optimization problem corresponding to each parameter valued x, our aim is to find the set of C-minimal point of the feasible set map G x The set-valued map ... results concerning the behavior of the perturbation map, and Shi studied some quantitative results concerning the behavior of the perturbation map Li 10 discussed the continuity of contingent derivatives...

Ngày tải lên: 21/06/2014, 05:20