... restricted for the first three days of therapy by NARP, the consumption of these quinolones was unsurprisingly high. Besides that the use of oral quinolones for maintenance may contribute to the significant ... the NARP, the resistance rates of E.coli and Klebsiella spp. against piperacil- lin-tazobactam did not increase significantly (rho:0.626, p=0.096 and rho:0.357, p=0.385, respec- tively). The ... we evaluated the effect of NARP on antibiotic consumption, antimicrobial resistance, and cost. Materials and Methods: The data obtained from all of the four university hospitals, and one referral...
Ngày tải lên: 25/10/2012, 11:00
... contributed to the design of the project and data analysis, and was primarily responsible for writing the manuscript. KVA contributed to the de- sign of the project, patient recruitment and manage- ment, ... subjects in the treatment groups. Taken together, these observations further demonstrate that 5-Lox i n đ and Aflapin đ are potentially safe in the treatment of OA in humans and more specifically ... cells helps in the diapedesis of these cells. Therefore, in order to determine whether 5-L oxin đ and Aflapin đ treatments can ameliorate the ICAM-1 expression, we evaluated the ICAM levels...
Ngày tải lên: 25/10/2012, 11:40
Báo cáo y học: " Polysaccharides from the root of Angelica sinensis protect bone marrow and gastrointestinal tissues against the cytotoxicity of cyclophosphamide in mice
... with the cytotoxic agent in cancer therapeutic regimen. In the present study, we investigated whether AP could protect the bone marrow and the gastrointestinal tissues from the cytotoxicity ... receiving chemotherapy, so as to allow their immune systems to restore function [2]. On the other hand, the death of GI cells breaks down the physical defence of GI system in the host who will ... down-regulated the protein levels of VEGF, c- Myc and ODC in the gastric mucosa (Fig. 4A, 4B and 4C respectively). There was a 73% decrease in the VEGF protein level and a 22% decrease in the c-Myc...
Ngày tải lên: 02/11/2012, 10:19
Tài liệu The King''''s Post Being a volume of historical facts relating to the Posts, Mail Coaches, Coach Roads, and Railway Mail Services of and connected with the Ancient City of Bristol from 1580 to the present time pdf
... noon on the eventful day, the Bath postmen's band, Mr. Kerans, the postmaster, and his lieutenants, the staff of postmen and messengers, marched on to the space between the Abbey and the Guildhall ... Richard Bright and Thomas Daniel and then Co-partners trading under the Firm of the Bristol Copper Company but then the property of the said James Ford on[Pg 13] the South part and extending ... lying and being behind and adjoining to the said last named messuage or Warehouse and then and for some time past in the occupation of Messrs. John Freeman and Copper Company and used by them...
Ngày tải lên: 17/02/2014, 02:20
Tài liệu Báo cáo khoa học: Ionic strength and magnesium affect the specificity of Escherichia coli and human 8-oxoguanine-DNA glycosylases pdf
... as Mg 2+ , the nature of the buffer- ing agents, the presence of competing polyamines and other small molecules, and crowding by other macro- molecules. Their effects on the speci city of 8-oxoG excision ... determination The reaction mixtures were as in the standard assay, except that the components specified in the Results were added, and the concentrations of the substrate and enzyme varied as required for the ... the omission of KP i had a rather minor effect on the speci city of both enzymes. Even less important for the activity and opposite-base speci city of Fpg and OGG1 were polyamines (spermine and...
Ngày tải lên: 18/02/2014, 18:20
Tài liệu Báo cáo khóa học: Active-site residues and amino acid specificity of the bacterial 4¢-phosphopantothenoylcysteine synthetase CoaB pptx
... synthesized in five steps from D -pantothenate. The Dfp flavoprotein catalyzes the synthe- sis of the coenzyme A precursor 4Â-phosphopantetheine from 4Â-phosphopantothenate and cysteine using the ... monomers with the monomer fold having features in common with a group of NAD-dependent enzymes on one hand and with the ribokinase fold on the other hand. The structure of the human PPC synthetase ... 4Â-phosphopantetheine and coenzyme A biosynthesis. With the used assay, it is difficult to evaluate the PPC synthetase activity at different temperatures, because the enzymatic activity of the present pantothenate kinase...
Ngày tải lên: 19/02/2014, 12:20
Tài liệu Cities for All Proposals and Experiences towards the Right to the City docx
... reinvent the city and reinvent itself within the city. 18 Cities for All The section on public policy and planning demonstrates how these tools can be counteractive to the right of the city and ... Countering the Right to the Accessible City: The Perversity of a Consensual Demand Yves Jouffe The right to the city constitutes a fundamentally anti-neoliberal concept: put the city to work for the ... unconventional alliances. From the Right to the City to the Right to Access Through the right to the city, inhabitants can exercise their rights to produce, transform, and to use the city. An initial simplification...
Ngày tải lên: 25/02/2014, 01:20
Báo cáo khoa họcRe-engineering the discrimination between the oxidized coenzymes NAD+ and NADP+ in clostridial glutamate dehydrogenase and a thorough reappraisal of the coenzyme specificity of the wild-type enzyme docx
... dehydro- genase and its speci city, but also has wider significance for the study of coenzyme speci city in other enzymes. Results and Discussion Initial kinetic analysis The coenzyme speci city of the mutant ... before the steady state is reached: the presence or absence of a burst provides information on the position of the rate- limiting step along the reaction pathway, and the amplitude of the burst ... resulting from splitting off the nicotinamide ring, suggesting that the covalent bond between the nicotinamide and the ribose of the coenzyme is particularly labile. The signal of the parental molecule...
Ngày tải lên: 06/03/2014, 00:20
Báo cáo khoa học: Functional analysis of a murine monoclonal antibody against the repetitive region of the fibronectin-binding adhesins fibronectin-binding protein A and fibronectin-binding protein B from Staphylococcus aureus pot
... binding of the ligand to the other repeats that share a common epi- tope. Other inhibition mechanisms cannot be excluded; among these, there is the possibility that, through the effect of the proximities ... 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide (0.2 m) and sulfo-NHS (0.05 m), and then injecting the ligand (30 lgặmL )1 in sodium acetate, pH 5.0 for the antibodies and pH 4.0 for Fn), at a ow rate of 30 lLặmin )1 . The remaining ... chemistry, and this was followed by the injec- tion of soluble repeats 9 or 10 of both FnBPA and FnBPB across the sensor chip surface. Table 2 reports the kinetic constants of the binding and the calculated K D values....
Ngày tải lên: 06/03/2014, 22:21
A Concise History and Directory of the City of Norwich for 1811 pptx
... Blomfield mentions several of these one in the time of Alfred the Great, about the year 872; another in the early part of the reign of Athelstan about the year 925, and several others; besides three coins ... improved many parts, and will when finished, add greatly to the beauty of the city, and to the convenience and comfort of the inhabitants and occasional visitors. The act for paving the streets, &c. ... coats and red caps, and altogether educated and maintained upon the foundation; and one for 24 girls, who where clothed in blue gowns, and educated and maintained upon the foundation. The original...
Ngày tải lên: 08/03/2014, 00:20
Báo cáo khoa học: Relation between domain evolution, specificity, and taxonomy of the a-amylase family members containing a C-terminal starch-binding domain pot
... 3B). Thus for the SBD tree there is not an obvious border between the hydrolases and transglycosi- dases, but rather there may be one between the compact cluster of Bacillus and Thermoanaerobacter ... 251 CGTase with the SBDs from the CGTases from Thermococcus sp. B1001, Bacillus ohbensis,andThermoanaerobacter thermosulfurogenes are 37.3%, 63.8% and 74.0%, respectively. Even for the acarviose ... supports the idea that there has been a separate evolution of this domain [30]. This together with the findings of the present study indicates a separate evolution of the domains C and E compared to the...
Ngày tải lên: 08/03/2014, 08:20
Begun and held at the City of Washington on Wednesday, the twenty-third day of January, two thousand and two potx
... consideration the size and nature of the business of the accounting firms they supervise and the size and nature of the business of the clients of those firms. The standards applied by the Board under ... Act and the rules of the Board and the Commission issued under this Act, in the same manner and to the same extent as a public accounting firm that is organized and operates under the laws of the ... reports and the obligations and liabilities of accountants with respect thereto, by registered public accounting firms and associated persons thereof; and (7) set the budget and manage the operations...
Ngày tải lên: 15/03/2014, 22:20
Banking Crisis: reforming corporate governance and pay in the City docx
... quality of the business, the risk management in the business; the second, it is the quantum of bonus that is paid and making sure that is in line with the relative success of the business and the ... corporate governance and pay in the City 7 banks and Banking Crisis: dealing with the failure of UK banks. We shall consider the public regulatory framework and the role of the tripartite authorities ... governance and pay in the City 2 Remuneration in the banking sector Introduction 6. The banking crisis has propelled the issue of remuneration practices in the banks to the top of the public...
Ngày tải lên: 19/03/2014, 11:20
ENVIRONMENT AND CRIME IN THE INNER CITY pptx
... about the incident describing the specific crime or crimes, the date, the address where the crime(s) occurred, and other pertinent information. Details from this report are then summarized in the ... of high-maintenance gardening. And in another study, Stamen (1993) surveyed landscaped and nonlandscaped areas in a community and found that the incidence of vandalism or graffiti in sites without ... is the average number of units rented in a partic - ular building during the 2 years of the study; the mean was 7.8, and the range was from 0.5 to 15. We were able to obtain data on 84 of the...
Ngày tải lên: 19/03/2014, 11:20
Fat City: Questioning the Relationship Between Urban Sprawl and Obesity doc
... controls. The third column (ols3) of tables 1 and 2 reports these results. Before considering the impact on the coefficients of the two landscape variables we briefly comment on the effect of each of the individual ... impact on the point estimates of the landscape variables for women. In the specifications that we report in the text, these correlations are not quite significant at the 10% level. In other specifications, ... residential-sprawl and high mixed-use) these differences in average bmi work against the correlation with the landscape variables. The dif- ferences in average weight are even more marked for black and Hispanic...
Ngày tải lên: 19/03/2014, 11:20
Begun and held at the City of Washington on Tuesday, the sixth day of January, two thousand and nine docx
Ngày tải lên: 23/03/2014, 10:20
Begun and held at the City of Washington on Tuesday, the sixth day of January, two thousand and nine potx
Ngày tải lên: 29/03/2014, 06:21
Hitting America’s Soft Underbelly -The Potential Threat of Deliberate Biological Attacks Against the U.S. Agricultural and Food Industry pot
Ngày tải lên: 29/03/2014, 16:20