cognitive science and the future of psychology— challenges and opportunities

... Echinocandins The echinocandins are one of the newest classes of antifungal agents that act by inhibiting cell wall synthesis They are semisynthetic lipopeptides that inhibit the synthesis of 1,3-b-d-glucan, ... with other drugs for treatment of chromoblastomycosis 1.2.4 Spectrum of Activity The spectrum of activity of 5-FC includes most species of Candida (except for C krusei) and C neoformans and Saccharomyces ... arrythmias There is little use of miconazole outside of treatment of dermatophyte infections, cutaneous Candida infections, and tinea versicolor With the advent of new azoles and echinocandins that offer...

Ngày tải lên: 29/05/2014, 16:51

... interpretation of the data, and wrote the first draft of the article BP, collaborated in the in the acquisition, analysis and interpretation of the data, and in the revision of the article SC, ... cancer in the Portuguese population, during the period 1980–2010, and to quantify the contribution of the variation in the population’s size and age structure, and ageindependent “risk” of death ... collaborated in the interpretation of the data and reviewed the article critically for important intellectual content KB, collaborated in the interpretation of the data and reviewed the article critically...

Ngày tải lên: 15/02/2014, 04:20

... bottom of the page These are then followed by the panel at the top of the page The next level of abstraction would be the middle panel on the right Finally, the panel to the left depicts the crowd ... concern over the nation’s future and a sense of crisis regarding print culture—they’re like the two sides of the coin.”6 In spite of these concerns, the official response by the government to the perceived ... recognizes the manga rendition as the urtext, and the caricaturization of the actor highlights the fact that she is not the same as the character In figure 2.6, the photo of the actor is shown with the...

Ngày tải lên: 27/03/2014, 12:25

... cells (one band) and the presence of a high level of NADP-GDH activity in the fungus (one major band and one minor band) Both GDHs were detected in spruce ectomycorrhizas (Fig A) In the Beech-H ... Dissection of the mycorrhizal tissues in spruce confirmed these results: the vascular cylinder free of fungus and the cortical region including host cells and fungal hyphae revealed identical isoforms, ... beech!ctomycorrhizas These results suggest that the repression may come from the host plant, since the same fungus gives rise to two kinds of responses depending upon the plants However, to date, the mechanism of...

Ngày tải lên: 09/08/2014, 04:20

... Members of the Notch family of cell surface receptors and their ligands also warrant attention based on their role in vasculogenesis and their potential to act as oncogenes in the pathogenesis of ... The authors contributed to this study as follows: CS, ZC and HL conceived of the study; CS, YS, YL, YL and BZ performed experiments; ZC and LC analyzed data and prepared the figures; CS, ZC and ... grade) of tumor cells in ESCC Lymphangiogenetic characteristics and their associations with NF-B and Notch1 signaling were also measured to determine Page of the contribution of NF-B and Notch...

Ngày tải lên: 10/08/2014, 10:21

... close linkage of 25S and 5S observed, and then only involving a minor 5S band Because Barbata is the most derived section in the genus (Figure 1), either its species have lost 25S and 5S rDNA loci, ... possess the same number of loci, it can be logically assumed that the difference in sequence polymorphism between the two groups is caused by the different locations of the 5S loci The fact that the ... tropical and subtropical Southeast Asia, is among the most widely grown and hybridized of all orchids Species of Paphiopedilum are also ecologically important narrow endemics in various mainland and...

Ngày tải lên: 11/08/2014, 11:21

... synthesized in the grape seed [11] The endo- and mesocarp of the berry contain large quantities of acids, primarily malic and tartaric acids, during the first growth phase, and sugars during the ... MYBPA1 and MYBPA2) are associated with the regulation of the structural genes in the flavonoid pathway MYBA1 and MYBA2 play roles in the biosynthesis of anthocyanins by activating the promoter of ... flavonoids in the berry skin, and the expression and regulation of the underlying genes are well understood in V vinifera Little is known, however, about the regulation of the biosynthesis of flavonoid...

Ngày tải lên: 11/08/2014, 11:21

... lower than the WT and TG9 that were close to each other, while the conjugated Spm level of TG9 was significantly higher than that of WT and TG4 Xac challenge of the transgenic plants and the WT Figure ... XZF drafted the manuscript, and JHL revised critically the manuscript and finalized it TM provided the MdSPDS1 and helped to analyze the data All of the authors have read and approved the final ... correlation exists between the transcription level of a biosynthetic gene and the product of the protein activity [37,44] In previous studies overexpression of the polyamine biosynthetic genes like SAMDC...

Ngày tải lên: 11/08/2014, 11:21

... of the sample, the sample size, the authors, and the study design in the first column, the age group of the sample in the second column, the timeframe of interviews in the third column, and the ... Prevalence of panic disorder and other subtypes of anxiety disorder and their background Japanese journal of psychiatry and neurology 1987, 41(1):9-18 Brugha TS: The effects of life events and social ... endorsed symptoms of depressed mood, loss of interest and/ or pleasure, and increased appetite and weight gain, and five additional subtypes varying according to their patterns and degree of classical...

Ngày tải lên: 11/08/2014, 17:20

... that they had reduced the number of pills they were taking on each occasion in an attempt to reduce the negative effects of the products Drug form and route of administration The main route of ... they often split this amount, and spread it over the course of the BZPparty pill-taking occasion Data from the pre-group/interview questionnaire showed that the median time before the first and ... [3]] By the time I get to the weekend I am pretty tired and I've got to make the most of the time that I have with my friends a lot of the time I make the most of going out and dancing so I don't...

Ngày tải lên: 11/08/2014, 18:20

... stress and TCRζ expression in RA T cells the possible role of NO Reduced GSH levels may contribute to the hyporesponsiveness of T cells from synovial fluid of RA patients [59,60] The expression of the ... [13] A central event in the antigen-specific interaction of T  cells with antigen-presenting cells is the formation of the immunological synapse, in which the TCR complex and the adhesion receptor ... Overexpression of eNOS was associated with increased phosphorylation of the CD3ζ chain, ZAP-70, and extracellular signal-regulated kinases, and increased IFN-γ synthesis, but reduced production of IL-2 These...

Ngày tải lên: 12/08/2014, 14:22

... sputum (IS) of COPD patients [20], we have assessed an expression of MMP-12 in IS and BAL cells from these COPD and healthy subjects groups Furthermore, we analysed if the decline of pulmonary ... groups According to Lofdahl et al [29] suggestions, the extent of emphysema (measured as an emphysema index and the One of the most interesting our findings was an increased number of MMP-12+-macrophages ... study design and in the sequence alignment RS participated in the study design and in the sequence alignment Also, a higher number of MMP-12+-macrophages in IS and BAL from COPD smokers and COPD...

Ngày tải lên: 12/08/2014, 15:21

... have intermediate proportions of CEs and RIs The difference in the proportions of RIs and CEs between the group of animals and the group consisting of all fungi and protists is highly statistically ... not only the splicing of the intron adjacent to the mutation, but also the intron on the other side of the exon adjacent to the mutation This causes cassette exons to be skipped [19,20] Therefore, ... them, and one made up of shorter exons recognized by ED and the surrounding longer introns When we examine the lengths of CEs, we sample from only one of these two distributions: the subset of...

Ngày tải lên: 14/08/2014, 08:20

... the slopes of Ni (the nucleotide content in the untranslated regions) and N3 (the nucleotide content at the third codon position) with the levels of gene expression as the descriptive index of ... codons) in the same species Although the biological bases of the variations of optimal codons remain an issue for further investigation, we hypothesize that one of the aspects of these pressures ... very limited Therefore, further study of the function of orthologous developmental-pivotal and developmental-specific genes will deepen our understanding of the higher Ks and Ka/Ks in these genes...

Ngày tải lên: 14/08/2014, 20:22

... variables The market depth is the sum of the dollar amounts of the buy and sell orders submitted at the best bid and offer prices The cumulative depth is the sum of the dollar amounts of orders at the ... properties The dummy variables, dmktval, dweek, and dtime denote the firm size, day of the week, and time of the day, respectively The dummy variables take the value of one if the observation of the ... low at the beginning and the end of the week This is consistent with the finding that on the NYSE liquidity is lowest on Mondays and Fridays and highest during the middle of the week The regression...

Ngày tải lên: 31/10/2014, 10:17

... INTRODUCTION TO THE THESIS 1.1 Introduction This chapter aims to provide an introduction to the area of the research and an outline of the thesis structure The focus of the thesis is to identify the patterns ... R&D managers and industrial designers, and other relevant documents The findings and discussion of case studies will be presented in Chapter and Chapter 1.3 Focus of the thesis The thesis focuses ... is the conception of the idea, whereas innovation is the subsequent translation of the invention into the economy” Based on the definitions, we can see the concepts of the term “invention” and...

Ngày tải lên: 28/11/2015, 13:33

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Ngày tải lên: 07/08/2014, 18:21

... are often multidrug-resistant and are resistant to antibiotics such as the macrolides and aminoglycosides, even though the mechanisms of action of these antibiotics are different than that of the ... Switzerland, the Netherlands (the SENTRY participants group, 2001)[43] and Australia (14.9%)[44] on the other hand, it is low In developing countries, it has always been contended that the inappropriate ... Specifically, they bind to the D-alanyl-D-alanine terminus of the N-acetylmuramyl pentapeptide subunit of the nascent cell wall On the basis of these and other observations, Sieradzki et al (1999)[8], proposed...

Ngày tải lên: 08/08/2014, 19:20

... whether IL-1α, TNF-α, IFN-γ and IL-4 could be detected in the T cell membranes of the clones used This was indeed the case IFN-γ was present in the membranes of all Th1 and in none but one of the ... on the capacity of T cells to elicit the production of chemokines by dermal fibroblasts and, in particular, the capacity of polarized T cells (Th1 and Th2) to modulate fibroblast production of ... human disease that is presumably of autoimmune origin and is characterized by vasculopathy and fibrosis of the skin and internal organs In the early stage of the disease, inflammatory infiltrates...

Ngày tải lên: 09/08/2014, 07:20