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Báo cáo khoa học: Apoptosis and autophagy: BIM as a mediator of tumour cell death in response to oncogene-targeted therapeutics pptx

Báo cáo khoa học: Apoptosis and autophagy: BIM as a mediator of tumour cell death in response to oncogene-targeted therapeutics pptx

Ngày tải lên : 16/03/2014, 00:20
... extracellular signal-regulated kinase kinase ⁄ mitogen-activated protein kinase inhibi- tors interact synergistically with STI571 to induce apoptosis in Bcr ⁄ Abl-expressing human leukaemia cells. Cancer ... several signalling pathways, includ- ing the ERK1 ⁄ 2 pathway, the PKB pathway and the Janus kinase ⁄ signal transducer and activator of tran- scription (JAK-STAT) pathway, to promote prolifera- tion, ... 912–919. 66 Kuroda J, Kimura S, Strasser A, Andreef A, O’Reilly LA, Ashihara E, Kamitsuji Y, Yokota A, Kawata E, Takeuchi M et al. (2007) Apoptosis-based dual mole- cular targeting by INNO-406, a second-generation Bcr...
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Ruta 6 selectively induces cell death in brain cancer cells but proliferation in normal peripheral blood lymphocytes: A novel treatment for human brain cancer doc

Ruta 6 selectively induces cell death in brain cancer cells but proliferation in normal peripheral blood lymphocytes: A novel treatment for human brain cancer doc

Ngày tải lên : 22/03/2014, 17:20
... fragmentation of DNA, leading to cell death; h) FACS analysis indicates that Ruta induces cell death in a dose- and duration-dependent manner in human MGR1 brain cancer cells, followed by saturation effects. ... intracranial brain cancers. The 15 patients (9 male, 6 female) with intracranial brain cancers who were treated with Ruta 6 + Ca 3 (PO 4 ) 2 at the PBH Research Foundation, Kolkata, India, had ... (P.B. and P.B.) have used Ruta 6 and Ca 3 (PO 4 ) 2 combination therapy to treat 15 patients diagnosed with advanced intracranial malignant brain cancer at the PBH Research Foundation, Kolkata, India....
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Báo cáo khoa học: RIP1 comes back to life as a cell death regulator in TNFR1 signaling docx

Báo cáo khoa học: RIP1 comes back to life as a cell death regulator in TNFR1 signaling docx

Ngày tải lên : 28/03/2014, 23:20
... 1477–1485. 62 Sasazuki T, Okazaki T, Tada K, Sakon-Komazawa S, Katano M, Tanaka M, Yagita H, Okumura K, Tominaga N, Hayashizaki Y et al. (2004) Genome wide analysis of TNF-inducible genes reveals that antioxidant enzymes ... 8, 592–600. 73 Ashida H, Kim M, Schmidt-Supprian M, Ma A, Ogawa M & Sasakawa C (2010) A bacterial E3 ubiqu- itin ligase IpaH9.8 targets NEMO ⁄ IKKgamma to dam- pen the host NF-kappaB-mediated in ammatory response. ... NF-kappaB activation [corrected]. Nat Cell Biol 8, 398–406. 18 Tokunaga F, Sakata S, Saeki Y, Satomi Y, Kirisako T, Kamei K, Nakagawa T, Kato M, Murata S, Yamaoka S et al. (2009) Involvement of linear...
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Báo cáo khoa học: Intermittent hypoxia is a key regulator of cancer cell and endothelial cell interplay in tumours pot

Báo cáo khoa học: Intermittent hypoxia is a key regulator of cancer cell and endothelial cell interplay in tumours pot

Ngày tải lên : 30/03/2014, 04:20
... 728–733. 72 Hayakawa M, Miyashita H, Sakamoto I, Kitagawa M, Tanaka H, Yasuda H, Karin M & Kikugawa K (2003) Evidence that reactive oxygen species do not mediate NF-kappaB activation. EMBO ... extracellular matrix degra- dation (matrix metalloproteases) [75–78]. In addition, NF-jB activation was reported as an early event in malignant transformation in vitro [79], and continuous activation ... FEBS transient hypoxia, extracellular signal-related kinase 1 ⁄ 2 mitogen-activated protein kinases and phos- phoinositide-3-kinase are not required for HIF-1 sta- bilization and transcriptional activity...
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financial simulation modeling in excel [electronic resource] a step-by-step guide

financial simulation modeling in excel [electronic resource] a step-by-step guide

Ngày tải lên : 31/05/2014, 00:26
... claimed as trademarks. In all instances where John Wiley & Sons, Inc. is aware of a claim, the product names appear in initial capital or all capital letters. Readers, however, should contact ... Come Preface ix It’s my belief that the combination of our skills and experience has been conveyed in an approachable, unintimidating, and clear manner. I hope that the pedagogical approach allows readers ... required. In our military simulation example, we would have a training area where the soldiers arrive with all of the training and gear one would expect, and then have an area with buildings and enemies...
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Báo cáo hóa học: "Regulatory T cell frequency in patients with melanoma with different disease stage and course, and modulating effects of high-dose interferon-a 2b treatment" pptx

Báo cáo hóa học: "Regulatory T cell frequency in patients with melanoma with different disease stage and course, and modulating effects of high-dose interferon-a 2b treatment" pptx

Ngày tải lên : 18/06/2014, 16:20
... behalf of International Malignant Melanoma Collaborative G: Interferon -a as adjuvant therapy for melanoma: an individual patient data meta-analysis of randomised trials. J Clin Oncol (Meeting Abstracts) ... 10 9 /L); adequate renal function (serum creatinine ≤ 1 × upper limit of nor- mal range [ULN]) and adequate liver function (serum bilirubin < 1.5 × ULN and aspartate transaminase/alanine transaminase ... and adequate cardiac func- tion. Exclusion criteria were: brain metastas es (including excised) and disseminated metastatic disease; a history of cardiac disease (e.g., angina, arrhythmia, cardiomi...
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Báo cáo hóa học: "IL-2 as a therapeutic target for the restoration of Foxp3+ regulatory T cell function in organ-specific autoimmunity: implications in pathophysiology and translation to human disease" doc

Báo cáo hóa học: "IL-2 as a therapeutic target for the restoration of Foxp3+ regulatory T cell function in organ-specific autoimmunity: implications in pathophysiology and translation to human disease" doc

Ngày tải lên : 18/06/2014, 16:20
... 62:101-107. 36. Kawasaki E, Awata T, Ikegami H, Kobayashi T, Maruyama T, Nakanishi K, Shimada A, Uga M, Kurihara S, Kawabata Y, et al: Genetic association between the interleukin-2 receptor-alpha gene and ... Cobbold S, Alyanakian MA, Gouarin C, Barriot S, Garcia C, Waldmann H, Bach JF, Chatenoud L: Autoimmune diabetes onset results from qualitative rather than quantitative age-dependent changes in pathogenic ... Passerini L, Allan SE, Battaglia M, Di Nunzio S, Alstad AN, Levings MK, Roncarolo MG, Bacchetta R: STAT5-signaling cytokines regulate the expression of FOXP3 in CD4+CD25+ regulatory T cells and...
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Báo cáo sinh học: "Shipping blood to a central laboratory in multicenter clinical trials: effect of ambient temperature on specimen temperature, and effects of temperature on mononuclear cell yield, viability and immunologic function" potx

Báo cáo sinh học: "Shipping blood to a central laboratory in multicenter clinical trials: effect of ambient temperature on specimen temperature, and effects of temperature on mononuclear cell yield, viability and immunologic function" potx

Ngày tải lên : 18/06/2014, 19:20
... Virginia. Data were analyzed with FlowJo software (Treestar, Ashland OR). Testing of Blood Shipping Packages The standard shipping container used in our clinical trials was obtained from Safeguard ... of the manuscript and editing. EF assisted in the gathering and organization of shipping data. RJF was instrumental in concept of study. ARC assisted in the in vitro stud ies and data analysis. ... were thawed and rested overnight at 37°C before staining with CD4, CD8, Annexin V and 7-AAD. The viable populations were defined as Annexin V negative and 7AAD negative and are expressed as a percentage of...
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Báo cáo sinh học: "A predicted protein, KIAA0247, is a cell cycle modulator in colorectal cancer cells under 5-FU treatment" ppt

Báo cáo sinh học: "A predicted protein, KIAA0247, is a cell cycle modulator in colorectal cancer cells under 5-FU treatment" ppt

Ngày tải lên : 18/06/2014, 19:20
... 82 R: CTCATGCTTCTTTCAACAGTGG Cyclin A2 NM001237 F: CCATACCTCAAGTATTTGCCATC 67 (CCNA2) R: TCCAGTCTTTCGTATTAATGATTCAG Cyclin B1 NM031966 F: CATGGTGCACTTTCCTCCTT 18 (CCNB1) R: AGGTAATGTTGTAGAGTTGGTGTCC Cyclin ... Yan-Chu Chen 2 , Chia-Long Lee 7 , Hao-Han Wu 4 and Chun-Chao Chang 8* Abstract Background: Colorectal cancer (CRC) is the predominant gastrointestinal malignancy and the leading cause of cancer ... Mountain View, CA). Total RNA extraction and reverse transcription reaction Total RNA from these cultured cells was extracted using the Easy Pure Total RNA Mini Kit (Bioman, Taipei, Tai- wan) according...
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