chitosan delivery systems for colon targeting

... Gene delivery systems 14 Viral gene delivery systems .14 Non-viral gene delivery systems 14 Naked (unformulated) nucleic acids .15 Barriers to non-viral gene delivery ... delivery systems for gene therapy of genetic or acquired human diseases has motivated the search for, and utilisation of, safer carrier molecules Non-viral delivery systems such as naked or formulated ... has been made, resulting in chitosan now being placed among the most effective non-viral gene delivery systems for mucosal application As for chitosan- mediated protein delivery, the most promising...

Ngày tải lên: 23/08/2015, 17:29

... Table 3.4 This information is similar to the information presented for a food ingredient/nutraceutical petition for FDA self-afÞrmed Generally Recognized as Safe (GRAS) status or for a health claim ... consume caffeine for performance Although sport beverages were originally designed for very competitive amateur and professional athletes, they are widely accepted as energy boosters for the average ... common tag line for these products is “Stimulation for Body and Mind.” The term stimulator beverage was chosen for this review rather than the more common terms of energy drink or performance enhancer...

Ngày tải lên: 25/10/2013, 21:20

... Laser II Viral and non-viral delivery systems (Non-physical delivery methods) including: Biological gene delivery systems (viral vectors) Non-biological gene delivery systems (non-viral vectors) ... from the environment prior to delivery and aid in targeting to a specific cell type for efficient delivery [1] Liposomes and polymers have also been utilized for the delivery of plasmid DNA, although ... Page of 20 Figure Live/non-live delivery systems Live or biological gene delivery systems include viral and/or bacterial vectors Non-live or nonbiological delivery systems mainly include cationic...

Ngày tải lên: 06/03/2014, 02:21

... suitable candidates for a nanoparticle-based drug delivery system to improve their pharmacological performance For this purpose, a “longboat delivery system” has been prepared for the platinum warhead ... photoluminescence, afford additional advantages for tracking and real-time monitoring of drug delivery efficacy in vivo Intracellular drug delivery To study the cellular drug delivery, in vitro ... used in drug delivery systems These functionalization methods provided candidate techniques, and there are great possibilities for them to be used in the construction of drug delivery systems in...

Ngày tải lên: 20/06/2014, 22:20

... light delivery systems In this thesis a new light delivery system consisting of the nano-aperture vertical-cavity surface emitting laser (VCSEL) as a potential candidate for an alternative light delivery ... Wakil Shehzad for their guidance, help and encouragement A special thanks to my i best friend Ms Nurjiha, for always being with me during all the ups and downs I owe these people a lot for everything ... power) in the far-field [53] Therefore it cannot be used for high power applications; a 50-nm circular aperture has a transmission efficiency less than 10-5 for visible light [54] Betzig et al...

Ngày tải lên: 09/09/2015, 08:17

... BACTERIAL VECTORS FOR ANTIGEN DELIVERY 22 1.5.1 Rationale for using a live bacterial vector 22 1.5.2 Attenuated pathogens 24 1.5.2.1 B pertussis as a live vector for nasal delivery of heterologous ... BORDETELLA PERTUSSIS AS A LIVE VECTOR FOR THE PRODUCTION AND MUCOSAL DELIVERY OF DENV2 EDIII 4.3 147 LACTOCOCCUS LACTIS AS A LIVE VECTOR FOR THE PRODUCTION AND MUCOSAL DELIVERY OF DENV2 EDIII 153 CHAPTER ... therefore indicated that BPZE1 was not ideal for the presenting EDIII to the respiratory mucosal immune system As an alternative approach, we chose the lactic acid bacterium L lactis for EDIII delivery...

Ngày tải lên: 09/09/2015, 08:18

... nanoparticle for targeted chemotherapeutic delivery of paclitaxel (Submitted for review) Wang Z., Liew G F., Ho PC Double targeting cRGD-HA-DSPE self-assembled PLGA core-shell nanoparticle for the delivery ... integrin targeting ligands for antitumor and antiangiogenesis activity (79-81) 1.3.2 Vascular targeted nanoparticle drug delivery Nanoparticulate delivery system surface modified with integrin targeting ... are generally two classes of targeting: active targeting and passive targeting Active targeting is programmed by engineering nanoparticle with cellular specific targeting moieties, whilst it...

Ngày tải lên: 11/09/2015, 09:58

... scaffolds as drug delivery systems for rhBMP-2 Biomaterials 2005; 26(17): 3739-3748 B Rai, S.H Teoh and K.H Ho An in vitro evaluation of PCL-TCP composites as delivery systems for platelet-rich ... PCL-TCP scaffolds 164 9.1.3 PCL-TCP scaffolds as delivery systems for a single growth factor 166 9.1.4 PCL-TCP scaffolds as delivery systems for multiple growth factors 167 9.1.5 Rat femoral ... protein delivery systems for the repair 28 of bone tissue The merit of the work was that the PCL-based scaffolds could serve not only as a template for bone growth but also as a delivery vehicle for...

Ngày tải lên: 15/09/2015, 17:10

... and information systems Other answers could come from comparing performance improvement for the eight topic areas created by QUERI with others not so targeted but still part of the VHA performance ... effort in progress, its delineation of strategies for different target audiences may be useful for others Berwick has described this scale-up/spread problem, identifying seven recommendations for ... 2009, 4:9 their use of a variety of performance measures to compare 12 community samples with 12 VA systems [2] Patients from the VHA scored significantly higher for adjusted overall quality (67%...

Ngày tải lên: 11/08/2014, 05:21

... 500 μl of chloroform were added to the suspension The mixture was maintained under agitation for 60 The sample was centrifuged at 14,000 rpm for and the supernatant was separated for analysis The ... Biodegradable polymers as drug delivery systems Edited by: Chasin M, Langer R New York, N.Y: Marcel Dekker; 1990:1-43 Barman SP, Lunsford L, Chambers P, Hedley ML: Two methods for quantifying DNA extracted ... Chemicals, Wankee, WI, USA) as surfactant, to form a stable water-in-oil in-water emulsion The mixture was stirred for h with a RW20 IKA homogenizer for solvent evaporation Microspheres were collected...

Ngày tải lên: 14/08/2014, 19:22

... vectors for cancer therapy, the mechanisms involved, and the foreseeable promises and problems when compared with existing viral vector systems The development and use of viral vector systems for ... progress [10] The intrinsic property of tumour-targeted colonisation of clostridia enables them to serve as "Trojan horses" for the delivery of genes for cancer therapy Indeed, clostridial spores that ... (DCs); Colony forming unit (CFU); Plaque forming unit (PFU); Epidermal growth factor receptor (EGFR); Herpes simplex thymidine kinase (HSV TK); Interleukin-2 (IL-2); Granule macrophage colony...

Ngày tải lên: 14/08/2014, 19:22

... successful formulation of a stable and effective dosage form therefore depends on the careful selection of excipients The use of polymers in the formulation of controlled drug delivery systems has ... opportunities and new challenges For commercial use, microspheres are formulated into pharmaceutically acceptable oral delivery systems, such as tablets, capsules and dry powder for reconstitution into ... compliance Such delivery systems are preferable for drugs which have high systemic toxicity and high administration frequency Typical examples include drugs for chemotherapy and proteins for certain...

Ngày tải lên: 13/09/2015, 20:39

... Physico-chemical properties 1 1.2 Colon- specific delivery systems 1.2.1 Rationale for colon targeting 1.2.2 Strategies for colon targeting 1.2.3 Pectin 1.2.4 Use of pectin for colon targeting 1.2.5 Single ... greatest potential for future clinical use Nevertheless, few colon- specific drug delivery systems have been commercialised To achieve colonspecific drug delivery, current approaches use systems that ... obtained from the perspective of colonic drug delivery Additional interest in colon- targeted drug delivery system has generated from the potential of the colonic site for the entry of some drugs into...

Ngày tải lên: 14/09/2015, 08:48

... suitable for this paper is the distinguishing between formal and informal institutions The examples of formal institutions are written laws and governmental regulations while examples of informal ... This makes Thailand a good location for utilizing PV systems The affordability challenge is more complex Historically prices for producing electricity with PV systems have not been competitive ... components The relevant type of linkage for this paper is interaction linkage between different actors [17] We separate it to formal and informal linkages By saying formal, we mean that it is an established...

Ngày tải lên: 05/09/2013, 16:10

... enforcing the lock at write time, for all writers, can be done using a trigger: CREATE TRIGGER tg_EnforceCustomerLocks ON Customers 249 CHAPTER DESIGNING SYSTEMS FOR APPLICATION CONCURRENCY FOR ... amount of profile form duplication as well as the fact that many of the forms are filed in the wrong order It would be a huge waste of time for the data input operators if, for instance, one ... DESIGNING SYSTEMS FOR APPLICATION CONCURRENCY Unfortunately, this approach is fraught with issues The first and most serious problem is that between the query in the IF condition that tests for the...

Ngày tải lên: 05/10/2013, 08:48

... s Don’t Forget the Central Office Today’s FTTP networks will also have implications for the central office environment For instance, where to place the WDM? There are advantages OLT for placing ... Performance Components – Rain or Shine They Always Work Picking Up the Slack in Cable Management The high-performance components used in ADC’s FTTP solution offer a wealth of robust features for ... connection for day-to-day business operations Times have changed Today, fiber is being deployed much deeper into the network, both for business and residential consumers The demand for high-speed...

Ngày tải lên: 18/10/2013, 14:15

... Need for Drug Delivery Systems Drug delivery systems modify the kinetics or the location of the escape of the drug from the medicine Tables 15.1 and 15.2 provide generic reasons for using drug delivery ... using drug delivery systems For drug delivery systems containing biodegradable polymers, the major motivations for clinical use have been to deliver drugs that are required for long periods, are ... been employed for over a decade in the treatment of glioblastoma multiforme, an aggressive tumor within the brain [5–7] In common with Zoladex, the systems used glioblastoma multiforme need to...

Ngày tải lên: 25/10/2013, 08:20

... Building Training Systems for the Global Workplace For over four decades, Lab-Volt has provided state-ofthe-art systems for technician training in the basic and most ... responsible for typographical errors TELECOMMUNICATIONS Technical Training Systems Known for Excellence in Technical Training Introducing Lab-Volt’s Award-Winning Training Systems for Analog & Digital ... in modern communications systems The Reconfigurable Training Module, Model 9431-1, used in the 8087 System is the same platform used for many other Lab-Volt Training Systems, such as the 8086...

Ngày tải lên: 06/11/2013, 11:15

... modules for four protected or four unprotected DS1s • Houses the alarm processor unit (APU) and craft performance monitoring module (CPM) for remote access and performance monitoring • Ideal for ... Processor Unit (MPU) •Common control unit for Loop Extender and Broadband systems •Provides extensive performance monitoring and status/alarm reporting for centralized system control •TBOS, TL1, ... density platform - distributes 28 DS1 circuits per chassis Uniquely designed for network growth Soneplex Features and Benefits Features • Unique platform which provides T1 service delivery over...

Ngày tải lên: 10/12/2013, 16:15