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iOS 5 Programming Cookbook phần 8 ppt
... presses the Home button and your application gets sent to the background The user then rotates the device from portrait, to landscape right, to portrait, and then to landscape left When the user ... lastName, and the age attributes of the Person entity and in the Data Model Inspector, make sure the firstName and the lastName attributes are not optional by unticking the Optional check box and make ... executingInBackground; @end And then let's synthesize our properties and write the getter method of the executin gInBackground property, called isExecutingInBackground: #import "Handling_Location_Changes_in_the_BackgroundAppDelegate.h"...
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iOS 5 Programming Cookbook phần 9 pdf
... [self.eventStore predicateForEventsWithStartDate:startDate endDate:endDate calendars: self.eventStore .calendars] ; NSArray *events = [self.eventStore eventsMatchingPredicate:predicate]; if ( [events ... [self.eventStore predicateForEventsWithStartDate:startDate endDate:endDate calendars: self.eventStore .calendars] ; NSArray *events = [self.eventStore eventsMatchingPredicate:predicate]; if ( [events ... [self.eventStore predicateForEventsWithStartDate:startDate endDate:endDate calendars: self.eventStore .calendars] ; NSArray *events = [self.eventStore eventsMatchingPredicate:predicate]; if ([events...
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Tài liệu Báo cáo Y học: Targeting of malate synthase 1 to the peroxisomes of Saccharomyces cerevisiae cells depends on growth on oleic acid medium pptx
... oligonucleotides H623 and H625 and Pfu high®delity polymerase (Stratagene, La Jolla, CA, USA) The single ampli®cation product obtained was digested with SphI and BglII, and ligated to an SphI- and BamHI-digested ... plasmid ampli®cations and isolations Construction of strains JD1, JR85, and JR86 has been described [5] To remove the three codons for SKL from the MLS1 gene, single-strand mutagenesis was performed ... respective strains KM10 and KM11 Correct integration of these plasmid fragments was veri®ed by polymerase chain reaction using oligonucleotide pairs H338 and H162, or H339 and H161, respectively...
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Báo cáo khoa học: Death inducer obliterator protein 1 in the context of DNA regulation Sequence analyses of distant homologues point to a novel functional role docx
... cultures from targeted (PHD and dPHD regions) and wild-type mice were fixed with methanol and acetic acid, mounted in Vectashield containing DAPI, and studied by standard fluorescence microscopy ... QLGI-CT-2001-01536, MEC and GenFun LSHG-CT-2004-503567 The Department of Immunology and Oncology was founded and is supported by the Spanish Council for Scientific Research (CSIC) and by Pfizer References ... DIDO1 and CGBP proteins (Fig 2) SPP1 also contains a PHD domain followed immediately by dPHD (Figs and 3) The domain architectures concur with the phylogenetic distribution of PHD (Fig 1) and the...
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Báo cáo khoa học: End-damage-specific proteins facilitate recruitment or stability of X-ray cross-complementing protein 1 at the sites of DNA single-strand break repair docx
... further recruits Pol b and XRCC1–DNA ligase IIIa to accomplish repair Among the known DSPs are APE1 and PNK which recognize and process 3¢ ends containing phosphoglycolate and phosphate groups, ... manufacturer Mammalian DNA single-strand break repair EDTA, 17% glycerol and mm dithiothreitol Extracts were divided into aliquots and stored at )80 °C Immunodepletion of WCEs and western blots Immunodepletion ... strand breaks and specific end-groups in DNA of irradiated thymocytes Int J Radiat Biol Relat Stud Phys Chem Med 27, 577–587 Coquerelle T, Bopp A, Kessler B & Hagen U (1973) Strand breaks and...
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Báo cáo khoa học: Solution structure of long neurotoxin NTX-1 from the venom of Naja naja oxiana by 2D-NMR spectroscopy pot
... [19,20]/TOCSY [19–21] and DQF-COSY [19,20,22] spectra, respectively NOESY and TOCSY spectra were acquired at 50, 100, 150 and 200 ms mixing times with 56 scans per each t1 increment, and 50, 75 and 150 ms ... Cys47-Cys58 and Cys59-Cy64, and are involved in a double- and a triple-stranded b-sheet, i.e the main regular secondary structures of NTX-1 Loop I (residues 1–15) constitutes a double-stranded antiparallel ... Fig The concave (left) and convex face (right) of NTX-1 The distribution of positive, negative and hydrophobic residues are shown in blue, red and white, respectively and 59% identity, respectively...
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Báo cáo hóa học: "Programmed cell death-1 (PD-1) at the heart of heterologous prime-boost vaccines and regulation of CD8+ T cell immunity" doc
... vaccination against HIV has expanded and resulted in hundreds of preclinical and clinical studies Interestingly, the most promising clinical regimens to date include: i) the RV144 landmark HIV ‘Thai trial’ ... nonreplicating vectors and biological response modifiers by direct intra-nodal administration of plasmid and peptide [19,41] We showed that the sequence and the route of administration of plasmid and peptide ... key feature and its underlying mechanism, with emphasis on DNA vaccines as priming agents and CD8+ T cell immunity as the desired outcome, as it pertains to the control of cancer and chronic...
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Chapter 1: Define the Art of Communication potx
... skills will be the ability to win friends and influence people at a personal level, the ability to structure partnerships, and the ability to negotiate and to find compromises Business will be ... Business will be much more about finding the right people in the right places and negotiating the right deals.” Charles Handy 2002 Negotiation Defined Process involving interested parties who • ... Mindfulness – alert to subtle changes or differences Active and effective listener Keen observer Always prepared Versatile and flexible in their communication style Overview of Text ...
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Báo cáo y học: " Egr-1 inhibits the expression of extracellular matrix genes in chondrocytes by TNF-induced MEK/ERK signalling" ppsx
... Agc1, Hapln1, and Col2a1, proteases Mmp-9 and Mmp-12, as well as the inflammatory cytokine macrophage Csf-1 (Figure 3) TNF decreased Agc1 and Hapln1 (Figure 3a, b) and increased Mmp-9 and Mmp-12 ... Figure Proximal promoters and overlapping binding regions for and and Egr-1 Proximal promoters of rat type II collagen and aggrecan, but not of link Proximal promoters and overlapping binding regions ... double-stranded ODN transfection conditions, chondrocytes were transfected cells with increasing concentrations of double-stranded, fluorescein-tagged and phosphorothiol-modified ODNs, and the...
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Báo cáo y học: "The role of interleukin-1 in the pathogenesis of human Intervertebral disc degeneration" pdf
... IL-1β, IL-1Ra, and IL-1RI), matrix-degrading enzymes (MMP-3, MMP-13, ADAMTS-4, and ADAMTS-5), matrix proteins (aggrecan and collagen types I and II), and two SOX genes (6 and 9) Primers and Probes ... work and analysis, and drafted the manuscript AJF conceived the study and participated in its design and coordination JAH conceived the study, participated in its design and coordination, and ... NP and IAF No significant difference was observed between the proportions of cells in the NP and IAF reacting for IL-1α, IL-1Ra, and ICE (P = 1.525, 0.870, and 0.639, respectively) IL-1β and...
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Báo cáo y học: "Catabolic stress induces expression of hypoxia-inducible factor (HIF)-1α in articular chondrocytes: involvement of HIF-1α in the pathogenesis of osteoarthritis" ppt
... sequence alignment, and drafted the manuscript HN, K H-M, TK, and KN conceived the study, participated in its design and coordination, and helped to draft the manuscript All authors read and approved ... detection system) using specific primers and probes (Table 2) The reaction was conducted as follows: 95°C for min, and 40 cycles of 15s at 95°C and at 60°C (21) To standardize mRNA levels, we amplified ... differentiation, and growth arrest in growth-plate chondrocytes [26] More recently, Coimbra and colleagues also showed that HIF1α is expressed in cultured cartilage and chondrocytes under both normoxic and...
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Báo cáo y học: " Tumour necrosis factor-α stimulates dehydroepiandrosterone metabolism in human fibroblast-like synoviocytes: a role for nuclear factor-κB and activator protein-1 in the regulation of expression of cytochrome p450 enzyme 7b" doc
... Netherlands), dissolved in dimethylsulfoxide or methanol and used as controls The proteasome inhibitor PSI and the JNK inhibitor SP600125 were purchased at Omnilabo (Breda, The Netherlands) and ... used between passages and 17 in the experiments Antibodies and reagents The anti-NF-κB-p65 was from Signal Transductions (Becton & Dickinson, Woerden, The Netherlands), and the biotinylated anti-mouse ... inhibitor of JNK – on Cyp7b mRNA expression and activity was assessed [16] The proteasome inhibitor PSI prevents degradation of IκB and thereby indirectly prevents NF-κB nuclear translocation [18]...
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Báo cáo y học: "The role of high-mobility group box-1 (HMGB-1) in the management of suspected acute appendicitis: useful diagnostic biomarker or just another blind alley?" docx
... Brugger LE, Candinas D: Negative appendicectomy and perforation rates in patients undergoing laparoscopic surgery for suspected appendicitis Br J Surg 2011 Sadr Azodi O, Andren-Sandberg A, Larsson ... A, Larsson H: Genetic and environmental influences on the risk of acute appendicitis in twins Br J Surg 2009, 96(11):1336-1340 Andren-Sandberg A, Korner H: Quantitative and qualitative aspects ... aetiology and pathogenesis which may eventually help us understand this disease better Finally, a drive towards nonoperative management of “non-complicated” appendicitis has been advocated through randomised...
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homomorphisms of the fundamental group of a surface into psu(1,1), and the action of the mapping class group
... Eleni, Alexandros and Pavlos Michaelidou; Antonio Colangelo and Mariagrazia Mecoli I thank them for being on my side all these years, for believing in me and for making my life in Tucson fun and enjoyable ... Georgia Papageorgiou and Anna Sidera for their continual support and the great summers I spent with them I thank my grandparents Panagiota and Charalambos Konstantinou, Maria Zeniou and my spiritual ... guidance, and advice, his continual encouragement and incredible patience, and for caring, during the years of my doctoral work I want to thank him especially, for being such an inspiration to me, and...
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Role of poly (ADP ribose) polymerase 1 and copper homeostasis factor, antioxidant protein 1 in the maintenance of genomic integrity
... single-stranded 3’ overhang of the G-rich strand (A) Specific protein complexes bind to the double- and single-stranded telomeric DNA (B) The single-stranded overhang can invade the double-stranded ... contains a leading and a lagging strand Lagging strand synthesis cannot be completed because the removal of primers thus causing net loss of DNA base pairs from the lagging strand (Hug and Lingner, ... cancer and aging Singapore • Balakrishnan L, Gurung RL, Hande MP (2007) Effect of Combined inhibition of PARP-1 and telomerase 5th Anniversary Congress of International Drug Discovery Science and...
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THE ROLE OF ANNEXIN 1 IN THE REGULATION OF INFLAMMATORY STRESS RESPONSE IN MACROPHAGES
... from the wells and washed times with wash buffer Standards and samples were then added to the wells with appropriate dilutions and incubated at room temperature for hours Standards and samples were ... JNK (Cargnello and Roux, 2011) JNK and of 46 and 52 kDa respectively exhibit vast tissue distribution while JNK 3, is localized to neural tissues, testis and cardiac myocytes (Bode and Dong, 2007) ... allowed me to learn from my mistakes and to better understand the subject matter Thank you also for always listening and being supportive of our dreams and endeavors and also wanting the best for us...
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Sphingosine kinase 1 regulates the expression of proinflammatory cytokines and nitric oxide in activated microglia
... tissue, and remove degenerating and dysfunctional cells (Harry and Kraft, 2008) The activated microglia in response to CNS inflammation secrete proinflammatory cytokines such as TNF-α and IL-1β and ... Carson and Sutcliffe, 1999, Frei and Fontana, 1997, Hickey and Kimura, 1988) Increases in TNF-α and IL-1β have been observed prior to neuronal death (Harry, et al., 2008, Lefebvre d'Hellencourt and ... important for growth and survival, whereas sphingosine and ceramide are associated with cell growth arrest and apoptosis (Ogretmen and Hannun, 2004) Therefore the balance between ceramide and sphingosine...
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Task 1 Explain the purpose of the following project document.
... the project as it currently stands and its future direction They also put the project’s progress into the context of where it stands compared to its original scope and objective because they holistically ... • Decisions reached and make by the project team • Activities and tasks accomplished • Milestones reached • Work still to be done • Any issues or problems that have arisen and need to be addressed ... materials, hire of equipment and administrative support) This will help in the management of spending & saving money D) Progress report: Regular progress reports should be prepared and should outline:...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha phần 3 giới thiệu nguyên liệu chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25