cell cycle dna replication transcription and translation worksheet
Báo cáo khoa học: Chromatin dynamics at DNA replication, transcription and repair pdf
... during DNA replication and the passage of DNA polymerases and helicases. In light of this, it is interesting to note that the FACT components Spt16 and Pob3 are found associated with DNA polymerase ... as well as through endogenous by-products of the cell s own metabolism. DNA lesions can cause physical obstacles to replication and transcription and they, as well as inherently occurring mismatches, ... the genome and binds to the lesion. Alternatively, stalled DNA processing complexes, such as the transcription or replication machineries, can send out signals that activate a cell cycle checkpoint,...
Ngày tải lên: 16/03/2014, 16:20
Báo cáo khoa học: The influence of cold shock proteins on transcription and translation studied in cell-free model systems pdf
... single-stranded DNA We suggest that the effects shown above are based on the binding of the CSPs to DNA and RNA. However, other possible mechanisms are the inhibition of transcription and ⁄ or translation ... m )1 ặcm )1 [35]. Template DNA for combined transcription/ trans- lation and in vitro transcription As template DNA the plasmid pK7CAT [36], pET14b CAT, pKRAS and pET14bRas and pET14bRas c were used. ... on the transcriptional or on the translational level, the system of combined transcription ⁄ translation was decoupled. The influence on the transcriptional level was investigated by in vitro transcription...
Ngày tải lên: 07/03/2014, 21:20
Tài liệu Báo cáo khoa học: The central role of CDE/CHR promoter elements in the regulation of cell cycle-dependent gene transcription pdf
... p53. Cell cycle arrest can be medi- ated by p53 downregulating the transcription of central cell cycle regulators such as cyclin B, Cks1, Cdc2 and Cdc25C. CDE CHR-dependent cell cycle- gene transcription ... be established which proteins contact DNA at which sites during late phases of the cell cycle. CDE ⁄ CHR-dependent cell cycle- gene transcription G. A. Mu ă ller and K. Engeland 884 FEBS Journal 277 (2010) ... encoded by cyclin B1 and cyclin B2 genes is Keywords cell cycle; cell cycle genes homology region (CHR); cell cycle- dependent element (CDE); DREAM complex; E2F Correspondence K. Engeland, Molecular...
Ngày tải lên: 16/02/2014, 09:20
Báo cáo y học: " Coordinate enhancement of transgene transcription and translation in a lentiviral vector" pps
Ngày tải lên: 13/08/2014, 09:21
Báo cáo y học: "Genomic context analysis in Archaea suggests previously unrecognized links between DNA replication and translation" potx
Ngày tải lên: 14/08/2014, 08:21
Modeling Cell Cycle Control and Cancer with pRB Tumor Suppressor
... Orc1 and Mcm2–7) and DNA replication (e.g. Dhfr, Rnr, TK, TS and Polα). Many E2F target genes encode products in- volved in cell cycle progression (e.g. cyclins A and E, pRB, p107, E2F1–3) and apoptosis ... mechanisms for controlling cell cycle progression (Morgan 1997; Zachariae and Nasmyth 1999). These studies and others demonstrated the universality of the cell Modeling Cell Cycle Control and Cancer with ... Nature 343:665–669 Modeling Cell Cycle Control and Cancer with pRB Tumor Suppressor 231 cycle, and strongly suggested that deregulation of the mechanisms controlling cell cycle progression could...
Ngày tải lên: 25/10/2013, 21:20
Senescence and Cell Cycle Control
... RA (1995) The role of Rb in cell cycle control. Prog Cell Cycle Res 1:9–19 Senescence and Cell Cycle Control 259 eliminates telomere-mediated signaling, allowing cells to undergo transform- ation ... loss of G1 control and immortalization. Genes Dev 14:3037–3050 Senescence and Cell Cycle Control 267 Campisi J (2001) Cellular senescence as a tumor-suppressor mechanism. Trends Cell Biol 11:S27–S31 Carnero ... mouse cells. p19 ARF is predominantly upregulated during senescence by oncogene activation and/ or oxidative stress Senescence and Cell Cycle Control 263 induction by controlling p16 INK4a (and...
Ngày tải lên: 25/10/2013, 21:20
The Retinoblastoma Gene Family in Cell Cycle Regulation and Suppression of Tumorigenesis
... most cell cycle responses. While each single pocket protein can mediate cell cycle arrest upon cell- cell contact, pRb is the critical mediator of cell cycle arrest upon growth factor deprivation and ... controlling cell cycle exit upon growth-inhibiting signals. Only ablation of all pocket proteins fully alleviated a cell cycle arrest upon serum withdrawal, cell- cell contact inhi- bition, DNA damage, ... consisting of Smad3 and specifically p107 and E2F4/5can translocate to the nucleus. These complexes subsequently bind to Smad4 and repress Myc transcription, thereby blocking cell cycle progression...
Ngày tải lên: 25/10/2013, 21:20
Tài liệu Báo cáo khoa học: Identification and characterization of the transcription factors involved in T-cell development, t-bet, stat6 and foxp3, within the zebrafish, Danio rerio docx
... effector cell populations exist, Th1, Th2 and Th17, characterized by their cytokine repertoire and how they regulate B -cell and T -cell Keywords adaptive immunity; fish immunology; T-cells; transcription ... shown that various unstimulated murine and human T-cells, B-cells, myeloid cells, monocytic cells and fibroblasts, but not neuronal cells or embryonic stem cells, express STAT6, indicating that ... of antibodies by B-cells, and for the elimination of extracellular pathogens, such as helminths and other extracellular parasites [2]. Th17 is the most recently identified Th cell subset and secretes...
Ngày tải lên: 16/02/2014, 09:20
Tài liệu Báo cáo khoa học: Protein kinase CK2 activates the atypical Rio1p kinase and promotes its cell-cycle phase-dependent degradation in yeast pdf
... phase of the cell- division cycle. Therefore, we tested, using light microscopy and after DAPI staining, whether the slow growth yields a cell- cycle phenotype. Cells of the logarithmically ... distribution of G 2 ⁄ M cells: the number of metaphase cells with a single DNA mass at the bud neck and the number of anaphase cells were increased slightly in the mutant (metaphase cells: 30.2% in the ... which is stable throughout the cell cycle and highly resistant to proteolytic degradation [40]. Miscellaneous procedures Yeast were grown on standard media [41] and transformed as described by...
Ngày tải lên: 18/02/2014, 16:20
Tài liệu Báo cáo khoa học: Human enhancer of rudimentary is a molecular partner of PDIP46/SKAR, a protein interacting with DNA polymerase d and S6K1 and regulating cell growth docx
... the ER and POLDIP3 genes. Array of 76 polyA + RNA samples isolated from various human adult and fetal tissues and cancer cell lines was hybridized with the radiolabeled ER cDNA probe (A) and after stripping ... pyrimidines. Experimental procedures cDNA cloning and DNA constructs cDNAs of the human genes, ER and POLDIP3 (both iso- forms) corresponding to their coding sequences (including the first ATG and stop codons) were ... proteome for Fig. 4. Comparison of the intracellular local- ization of ER and PDIP46 ⁄ SKAR fused to EGFP in the mammalian cells. NIH ⁄ 3T3 cells (upper) and HeLa cells (lower) were transi- ently transfected...
Ngày tải lên: 19/02/2014, 05:20
Báo cáo khoa học: 3 Cdt1 and geminin are down-regulated upon cell cycle exit and are over-expressed in cancer-derived cell lines potx
... licensing DNA for a further round of DNA replication. When G1 cells exit the cell cycle and enter quiescence, licensing is gradually lost. W e show her e that Cdt1 is down-regulated when cells are ... during the cell cycle [13], upon exit and entry to the cell cycle both genes are controlled, at least in part, transcriptionally. Cdt1 and geminin are highly expressed in proliferating cells in ... upon cell cycle exit. To this effect, HFF cells were deprived of serum f or 48 h to induce cell cycle exit. Serum was th en r e-added a nd samples taken as cells progressed into the cell cycle. ...
Ngày tải lên: 07/03/2014, 16:20
DNA Replication and Related Cellular Processes Edited by Jelena Kušić - Tišma pdf
... correlates with the cell cycle phase: cells in G1 have a ploidy of 2n; S phase cells between 2n and 4n; and cells in the G2 and M phases 4n. To measure the DNA content, animals are fixed and stained ... conclusion, DNA replication and cohesion establishment are intimately coordinated (Sherwood et al., 2010): replication forks, travelling along the DNA, modify cohesin's DNA Replication and ... and specific cell types. Several techniques used for analysis of DNA replication in C. elegans are summarized in BOX 1. 3. The factors that regulate DNA replication The regulation of DNA replication...
Ngày tải lên: 08/03/2014, 19:20
Báo cáo khoa học: Injection of poly(b-L-malate) into the plasmodium of Physarum polycephalum shortens the cell cycle and increases the growth rate pot
... in growth and cell cycle duration. However, we do not know how great an effect should be expected. If we assume that certain PMLA–protein complexes are involved in growth and cell cycle timing, ... the periodic activation of DNA polymerases in the cell cycle [11]. The degree of competition depends on the concentration of free PMLA, DNA, and the binding affinity and follows saturation functions. ... proteins, enzymes, and regulatory proteins. A recent analysis of DNA synthetic activities in extracts of plasmodia revealed a cell cycle dependent inhibition and activation of DNA poly- merases....
Ngày tải lên: 16/03/2014, 18:20
Báo cáo khoa học: "Braille Transcription and Mechanical Translation" pptx
... r"occupies three cells. In the second case the translation occupies three cells since "er" is a single -cell contraction. By rule 35 "o n er" is the correct translation of ... of the whole program and, in particular, of the dictionary. [ Mechanical Translation , vol.2, no.3, December 1955; pp.50-53] Braille Transcription and Mechanical Translation John P. ... the dictionary and precedes "one". "Oner" may be contracted in two ways - "one r" and "o n er. "In the first case "one" is a two -cell contraction...
Ngày tải lên: 16/03/2014, 19:20