card15 nod2 atg16l1 and il23r genes in polish crohn s disease cd patients are they related to the localization of the disease and extra intestinal symptoms
Infliximab therapy in pediatric Crohn’s disease: a review docx
Ngày tải lên :
22/03/2014, 10:20
... Dovepress Parashette et al to frequent relapses and less than favorable maintenance of clinical remission Since CD may progress from intestinal inflammation to strictures and penetrating disease, including ... pathophysiology of gastrointestinal disease; Investigation and treatment of gastointestinal disease; Pharmacology of drugs used in the alimentary tract; Immunology/genetics/genomics related to gastrointestinal ... coworkers showed that once patients achieved disease remission on mesalamine, less than 50% of patients were able to sustain disease remission after one year of maintenance therapy.9 Although studies...
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Tài liệu Báo cáo khoa học: Emerging pathways in genetic Parkinson’s disease: Autosomal-recessive genes in Parkinson’s disease – a common pathway? docx
Ngày tải lên :
18/02/2014, 14:20
... essential role for Parkin in oxidative stress [77] and Drosophila Parkin mutants show increased sensitivity to oxidative stress [78] Implication of PINK1 in oxidative stress processes has also ... membranes in human brain tissue Although a cytoplasmic pool of PINK1 has been described [16,17] PINK1 is of great interest to research into mitochondrial dysfunction in PD PINK1 Autosomal recessive genes ... Fitzgerald and H Plun-Favreau Autosomal-recessive Parkinson s disease genes and proteins Parkin (PARK2) Mutations in PARK2 were first reported in patients with autosomal-recessive juvenile-onset PD...
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báo cáo sinh học:" Non-European Union doctors in the National Health Service: why, when and how do they come to the United Kingdom of Great Britain and Northern Ireland?" pdf
Ngày tải lên :
18/06/2014, 17:20
... training also responded to the study We used these responses in the analysis, but this negligible group of responses does not affect the overall statistics in any meaningful manner All respondents ... trainees, Senior House Officers or House Officers), 17.8% in middle-grade training posts (Specialist Registrar, Locum Appointment for Training) and 11.9% in non-consultant, non-training posts (Staff ... Doctors) had to be increased several times to cope with the demand, with the GMC finally opting to set up a custom built examination centre to hold these tests on a daily basis Also, some NHS...
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báo cáo hóa học:" Respiratory symptoms in adults are related to impaired quality of life, regardless of asthma and COPD: results from the European community respiratory health survey" docx
Ngày tải lên :
20/06/2014, 16:20
... compared to subjects without these diseases Additional analyses assessing the respiratory symptoms- HRQoL relationship in those with asthma and in those with COPD separately showed that these relationships ... Breathlessness at rest was the symptom related to the lowest score, both for PCS and MCS The least impairment in the scores was observed in subjects with cough in the night A similar pattern of score ... summarized in a factor This yields an estimate of the association between having one of the symptoms in the factor, regardless of which, and HRQoL The factors substituted the observed symptom variables...
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Báo cáo khoa học: "Genetic determination of vessel area in oak (Quercus robur L and Q petraea Liebl): a characteristic related to the occurrence of stem shakes" docx
Ngày tải lên :
08/08/2014, 19:21
... during early thinning operations Some of these aspects have been discussed further by Savill and Mather (1990) shake, Tree mean vessel areas, expressed in μm , determined from radial measurements ... area is under strong additive genetic to et al (1991) Relationship between and vessel sizes flushing dates showed clearly that earlytrees tend to have vessels of Results flushing smaller cross-sectional ... Lower Saxony, Germany The experiment, established in 1950, consisted of 32 half-sib families of Q robur planted in an unreplicated design Investigations into the association between the progress of...
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Báo cáo khoa học: " Chemotherapy followed by low dose radiotherapy in childhood Hodgkin''''s disease: retrospective analysis of results and prognostic factors" ppt
Ngày tải lên :
09/08/2014, 10:21
... patients' symptoms Study end points This study retrospectively analysed 15 years of experience in the treatment of Hodgkin 's disease in childhood The primary end point was to evaluate prognosis ... III in 55 patients (33.1%), and IV in 32 patients (19.1%) B symptoms were present in 112 patients (67.5%) The median symptoms time until diagnosis was months, the most common manifestation was ... CCG-5942 study, the combination of B symptoms and bulky disease was associated with an inferior outcome [28,31,33,34] In our analysis radiotherapy administration, early clinical stage, no B symptoms, ...
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báo cáo khoa học: " The YlmG protein has a conserved function related to the distribution of nucleoids in chloroplasts and cyanobacteria" pdf
Ngày tải lên :
12/08/2014, 03:21
... activity of the photosystems [29,30,32] However, in Synechocystis sp PCC6803, which has two YlmG -related genes, disruption of ssl0353 reduced the activity of the photosystems, while disruption of ssr2142 ... http://www.biomedcentral.com/1471-2229/10/57 Then the morphology of chloroplasts in the AtYLMG11 antisense line was observed under microscopy (Figure 3D) In contrast to the overexpresser, the shape and size of chloroplasts in expanding ... the localization of FtsZ in the antisense line and the wild type (Figure 3E) In the antisense line, FtsZ localization was observed at the chloroplast division site, as in the wild type These results...
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An analysis of errors related to the uses of english prepositions at, on, in produced by elementary level students at foreign languages & informatics center vinh city
Ngày tải lên :
18/12/2013, 10:04
... in using the prepositions “AT, ON, IN ? What are the possible causes of the errors? What are the possible solutions to students’ errors related to the use of “AT, ON, IN as prepositions of place ... This task required students to build the sentences using suggested words and phrases We focused on checking the use of prepositions, so that any errors in tenses and mistakes in spelling are ... diagnosis tests of English prepositions are conducted to test the subjects’ proficiency in using prepositions AT, ON, IN of time and place The test (for prepositions of place) consists of exercises...
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Tài liệu Báo cáo khoa học: Emerging pathways in genetic Parkinson’s disease: Potential role of ceramide metabolism in Lewy body disease pptx
Ngày tải lên :
18/02/2014, 14:20
... DES, desaturase; GALC, galactosylceramidase; GBA, glucosylceramidase; GCS, glucosylceramide synthase; SMS, sphingomyelin synthase; SMse, sphingomyelinase; SPT, serine palmitoyl transferase Yellow ... key role in our understanding of the mechanisms of the disease We propose that pathology data will, in most cases, be more insightful than clinical data in defining the disease This is based on ... transport of cholesterol to post-lysosomal destinations Cells from NPC subjects show a decrease in acid sphingomyelinase activity, leading to the accumulation of sphingomyelin [27] Because one of...
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Is Lactobacillus GG Helpful in Children With Crohn’s Disease? Results of a Preliminary, Open-Label Study docx
Ngày tải lên :
05/03/2014, 12:20
... perpetuation of the disease( 13,14) It has been hypothesized that the intestinal inflammatory response is the result of an exaggerated intestinal host immune response to commensal enteric bacteria or their ... Crohn s disease and their healthy relatives, which supports the role of mucosal barrier defect in initiation of Crohn s disease (15) The normal intestinal microflora may offer resistance to colonization ... effective in treatment of Crohn s disease by several potential mechanisms such as altering the intestinal mucins, promoting local immune response, and stabilizing the gut mucosal barrier Lactobacillus...
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Báo cáo khoa học: Expression and characterization of the protein Rv1399c from Mycobacterium tuberculosis A novel carboxyl esterase structurally related to the HSL family docx
Ngày tải lên :
07/03/2014, 16:20
... consistent with our biochemical data As expected, Rv1399c consists of three domains The largest domain encompasses strands b1 to b6 and strand b7 to the C-terminus The central b sheet is composed ... bacterial strains, different temperatures, media and fusion protein constructs were unsuccessful In all cases, the recombinant protein was expressed as inclusion bodies with the highest expression level ... attack of the substrate ester bond by the serine alcoholate The shape of the titration curve of the catalytic histidine shows an apparent pKa value of the essential histidine estimated to 4.1...
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Báo cáo khoa học: Amyloid-b protofibril levels correlate with spatial learning in Arctic Alzheimer’s disease transgenic mice docx
Ngày tải lên :
23/03/2014, 06:20
... when symptoms begin to appear, but disease severity does not relate to the density of Ab deposits By contrast, in transgenic mice, functional deficits and loss of synapses are, at least in some ... and leads to AD [17,18], suggesting that these, and possibly also other soluble Ab aggregates, are causes of AD pathogenesis In an effort to examine the pathogenic role of Ab protofibrils in vivo, ... USA) Custom-made macros were used to measure the stained area of interest as percentage of total tissue area Biochemical Ab analysis Cortical and cerebellar brain tissues from perfused animals were...
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Báo cáo Y học: Structural study on lipid A and the O-specific polysaccharide of the lipopolysaccharide from a clinical isolate of Bacteroides vulgatus from a patient with Crohn’s disease ppt
Ngày tải lên :
31/03/2014, 23:20
... was established by NMR and MS The 1H NMR signals of the isolated lipid A were assigned using DQF-COSY and TOCSY, and the data are summarized in Table Two sets of sugar signals were observed The ... signals were mainly observed, and the corresponding sugars were designated as a and b in order of 1H chemical shift The 1H signals were assigned using DQF-COSY, TOCSY and ROESY spectra, and the ... was used as a matrix The sample was ionized with KeV Xe atoms, and the ions were accelerated through 10 KeV Argon was used as the collision gas RESULTS AND DISCUSSION Analysis of LPS As shown in...
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Báo cáo hóa học: " Robot-aided therapy for upper limbs in patients with stroke-related lesions. Brief report of a clinical experience" ppt
Ngày tải lên :
19/06/2014, 08:20
... perform specific exercises over time The system is capable of measuring and displaying the patient s progress The screen displays the activities of the patient on the machine, according to exercise ... treatment The increase in the motor FIM™ and the decrease on the VAS for the pain might be due to different strategies developed by the patients for compensating their motor deficits This data is in ... possible result of the process of adaptation In addition, it was also possible to observe a motor learning and generalization process, confirmed by the baseline improvements observed at T1 and...
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báo cáo hóa học:" Subacromial impingement in patients with whiplash injury to the cervical spine" docx
Ngày tải lên :
20/06/2014, 01:20
... impingement syndrome This involved a full examination of the neck and shoulder and assessing for evidence of subacromial impingement The diagnosis was made on the basis of the following clinical ... medicolegal assessment) was not, however, routinely obtained A total of 56/220 patients (26%) had shoulder pain following the injury, of these 11/220 (5%) had signs and symptoms consistent with subacromial ... alone [7] If the injury was sustained in a Motor Vehicle Accident (MVA) the position of the patient in the car, site of impact and the use of headrests and seatbelts were documented In this paper...
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báo cáo hóa học:" Serous papillary adenocarcinoma possibly related to the presence of primitive oocyte-like cells in the adult ovarian surface epithelium: a case report" docx
Ngày tải lên :
20/06/2014, 08:20
... diameters of up to μm (Figures 4A, B and 5B, F) resembling VSELs and bigger ones with diameters of around 10 μm (Figures 4, 5) VASA staining also confirmed the presence of rare positively stained ... for the presence of putative stem cells The analysis confirmed the presence of round, SSEA-4 and SOX-2-positive primitive oocyte-like cells in the ovarian surface epithelium These cells resembled ... epithelium of fetal ovaries, and might have been involved in the manifestation of serous papillary adenocarcinoma in this patient They expressed the analyzed markers of pluripotency SSEA-4 and SOX-2...
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ON THE ALGEBRAIC DIFFERENCE EQUATIONS un+2 un = ψ(un+1 ) IN R+ , RELATED TO A FAMILY ∗ OF pdf
Ngày tải lên :
23/06/2014, 00:20
... gives again, in a simpler way, results of [5], and improvements of them In Section 5, we study the case a = 0, where the quartic passes through the point (0,0) This case is easy, because a simple ... whose solutions are studied in [4] Then the results in Theorem 5.1 are nothing but [4, Proposition 11 and Theorem 6] The case of 5-periodicity in [4] corresponds to the values α = and β = (see ... zero Then E(K) splits into a conic and the line at in nity, that is Γ(K) splits into its asymptote U = −1/ p(K) and a conic (besides one see easily that the left hand of (6.17) has the factor...
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Báo cáo toán học: "COMPOSITION SUM IDENTITIES RELATED TO THE DISTRIBUTION OF COORDINATE VALUES IN A DISCRETE SIMPLEX" pptx
Ngày tải lên :
07/08/2014, 06:20
... and n − 1, there are more l-element subsets A of S (n) such that πy (A) is sparse, than there are l-element subsets A such that πx (A) is sparse Indeed, the number of l-element subsets A of S ... need to define two notions of sparseness for subsets of S (n) Let us call a multiset M of integers sparse if M does not contain duplicates, and if |a − b| ≥ for all distinct a, b ∈ M Let us also say ... there are more l-element subsets A of S (n) such that π3 (A) is sparse, than there are l-element subsets A such that π1 (A) is 2-sparse Proof Let us note that the number of points in S (n) such...
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Báo cáo sinh học: "Mycobacterium avium subsp. paratuberculosis linked to Crohn''''s Disease and Paratuberculosis" pot
Ngày tải lên :
08/08/2014, 19:20
... regimens against MAP In conclusion, these results might represent a good starting point to consider different drugs for treatment of the disease forms where involvement of MAP is suspected, in particular ... avium subspecies paratuberculosis from intestinal mucosal biopsies of patients with and without Crohn' s disease in Sardinia Am J Gastroenterol 2005, 100:1537-1538 Bull TJ, McMinn EJ, Sidi-Boumedine ... 16 STR: Streptomycin, CPX: Ciprofloxacin, EMB: Ethambutol, DPS: Dapsone, RIF: Rifampin, RIB: Rifabutin, CLA: Clarithromycin Source of isolation of strains is also indicated Numbers represent the...
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