calcium distribution in human body

Tài liệu Color Atlas of Pharmacology (Part 3): Distribution in the Body docx

Tài liệu Color Atlas of Pharmacology (Part 3): Distribution in the Body docx

... Plasma Proteins Having entered the blood, drugs may bind to the protein molecules that are present in abundance, resulting in the formation of drug-protein complexes. Protein binding involves primarily ... al- bumin and, to a lesser extent, !-globu- lins and acidic glycoproteins. Other plasma proteins (e.g., transcortin, trans- ferrin, thyroxin-binding globulin) serve specialized functions in connection with ... resupplied from binding sites on plasma proteins. Binding to plasma pro- tein is equivalent to a depot in prolong- ing the duration of the effect by retard- ing elimination, whereas the intensity of...

Ngày tải lên: 22/01/2014, 00:20

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Báo cáo Y học: Role of three isoforms of phospholipase A2 in capacitative calcium influx in human T-cells pot

Báo cáo Y học: Role of three isoforms of phospholipase A2 in capacitative calcium influx in human T-cells pot

... Capacitative calcium in ux in human T-cells (Eur. J. Biochem. 269) 5559 was added during the spike of ionomycin. In order to probe the role of different calcium channels, implicated in AA- induced calcium ... 1.04 n M ). AA-induced calcium in ux is contributed by opening the calcium channels We were tempted to assess whether AA-induced calcium in ux is contributed by the opening of calcium channels. ... extracellular calcium intrusion [28]. Figure 5 shows that addition of AA, during the ionomy- cin-induced spike, evoked an additive sustained response in [Ca 2+ ] i in Jurkat T-cells. Hence, ionomycin-induced...

Ngày tải lên: 08/03/2014, 09:20

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Báo cáo Y học: Irregular spiking in free calcium concentration in single, human platelets Regulation by modulation of the inositol trisphosphate receptors ppt

Báo cáo Y học: Irregular spiking in free calcium concentration in single, human platelets Regulation by modulation of the inositol trisphosphate receptors ppt

... results indicate that both InsP 3 -generating (thrombin) and non- InsP 3 -generating (sulfhydryl reagents) agents cause irregular [Ca 2+ ] i spiking in platelets. The thrombin-induced spiking and ... Ca 2+ responses in platelets, but in this case in the absence of InsP 3 generation. Throm- bin-induced spiking was acutely abolished by inhibiting phospholipase C or elevating intracellular cAMP ... used by InsP 3 , in a way insensitive to heparin and cAMP. Puff-like characteristics of [Ca 2+ ] i spiking in single platelets To determine the involvement of different Ca 2+ stores in the [Ca 2+ ] i spiking...

Ngày tải lên: 17/03/2014, 17:20

10 533 0
Cambridge.University.Press.Who.Believes.in.Human.Rights.Reflections.on.the.European.Convention.Oct.2006.pdf

Cambridge.University.Press.Who.Believes.in.Human.Rights.Reflections.on.the.European.Convention.Oct.2006.pdf

... and Legal Theory Twining: Rethinking Evidence Twining & Miers: How to Do Things with Rules Ward: A Critical Introduction to European Law Ward: Shakespeare and Legal Imagination Zander: Cases ... Convention GiventhatthecasesIdiscussinthebookaremerelyillustrative,thereisastrong elementoffortuityinthewaythefive‘criticallight’chaptersareassembled.The imageofthekaleidoscopecomestomindinthatitpointstoaninfinitenumberof combinationsofeithertheoreticalorempiricalelements,orboth.Ineachchapter itisasifIhadcollectedpiecesofcaselaw,shakenthem,andobservedthe resultingcombination–ifnotexactlysymmetry–inthemirror(orlight)of aparticulartheory.Icouldhaverepeatedtheexerciseoverandoveragain, adinfinitum,eitherwiththesameorwithslightlydifferentmaterial(caselaw) ormirrors(critiques). 30 Eachtimetheresultwouldhavebeendifferentbut, Iwouldargue,nolesscompelling. Theimageofthekaleidoscopedrawsattentiontothewayoursensesconstruct patternswhichdonot‘really’existexceptthroughtheartificeofreflection (theory).ItcouldbesaidthatIofferakaleidoscopicreadingoftheConvention, i.e.onegeneratingarrangementswhichare,ifnotaestheticallypleasing,atleast deceptivelyattractiveintheirsimplicityand(imposed)regularity.Afriendwho readChapter3wasnotdeceived.Sheremarked,disapprovingly,thatitwasas though ... Who Believes in Human Rights? The Law in Context Series Editors: William Twining (University College London) and Christopher McCrudden (Lincoln College, Oxford) Since 1970 the Law in Context series...

Ngày tải lên: 21/09/2012, 11:02

340 742 3
Kogan.Page.Managing.Projects.in.Human.Resources.Training.and.Developement.Apr.2006.eBook-DDU.pdf

Kogan.Page.Managing.Projects.in.Human.Resources.Training.and.Developement.Apr.2006.eBook-DDU.pdf

... quite structured in helping everyone to identify options before rushing into decisions about potential solutions. 26 Managing projects in human resources could be made by improving information about ... project. The monitoring information can be reviewed against the plan to show whether everything is proceeding according to the plan. If not, the project 4 Managing projects in human resources Figures ... perspectives in complex settings. Moreover, everyone in the setting who should normally be included in shaping and focusing the project is likely to be very busy and concerned with meeting immediate...

Ngày tải lên: 21/09/2012, 17:33

225 1,2K 6
Báo cáo y học: "Functional genomics analysis of low concentration of ethanol in human hepatocellular carcinoma (HepG2) cells. Role of genes involved in transcriptional and translational processes"

Báo cáo y học: "Functional genomics analysis of low concentration of ethanol in human hepatocellular carcinoma (HepG2) cells. Role of genes involved in transcriptional and translational processes"

... . Interestingly, HMGN3 has been found to be associated with resistance against anticancer drugs including vinblastine, topotecan, paclitaxel and doxorubincin in human hepatocellular carcinoma ... ethanol-induced mucosal injury in the upper gastrointestinal tract leading to increase in the permeability of the gut mucosa to endotoxins [43, 44]. These factors are involved in ethanol-induced ... signaling. This finding corroborates the interaction observed between various intracellular signaling pathways and apoptosis induced by 1mM concentration of ethanol in HepG2 cells [19]. Int....

Ngày tải lên: 31/10/2012, 15:28

8 704 0
SCARAB BEETLES IN HUMAN CULTURE

SCARAB BEETLES IN HUMAN CULTURE

... Raha in the Solomon Islands. The Kiriwinians, a Melanesian people inhabiting the Trobriand Islands, ate a variety of insects, including the larvae of the rhinoceros beetle, Scapanes sp. (Dynastinae) (Meyer-Rochow ... people who live in the Central Highlands of New Guinea, eagerly sought out all animals for food, including the wood boring and root feeding larvae of scarabs. The Onabasulu, inhabiting an area north ... consumption of insects is being reinforced by the increasing scarcity of larger game rather than disappearing under the impact of acculturation. Non-food uses of scarabs in Latin America are...

Ngày tải lên: 24/04/2013, 10:07

18 358 0
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