cac ung dung cua vi he thong ade 775x
Báo cáo y học: "Receptor for advanced glycation end products Glycine 82 Serine polymorphism and risk of cardiovascular events in rheumatoid arthritis" potx
... deemed hemorrhagic, the history was not included The body-mass index (BMI) was calculated as weight in kilograms divided by the square of the height in meters Blood pressure was measured at the time ... JF, Cooper NS, Healey LA, Kaplan SR, Liang MH, Luthra HS, et al.: The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis Arthritis Rheum 1988, 31:315-324 ... patients with rheumatoid arthritis with an onset in the 1980's and 1990's Ann Rheum Dis 2005, 64:1595-1601 28 Wang L, Feng G: Rheumatoid arthritis increases the risk of coronary heart disease via vascular...
- 8
- 330
- 0
Báo cáo y học: "levels of soluble receptor for advanced glycation end products in patients with rheumatoid arthritis indicating deficient inflammatory control" docx
... against Rheumatism, the Göteborg Association against Rheumatism, the King Gustaf V foundation, the Swedish Medical Research Council, the Nanna Svartz Foundation, Stiftelsen Goljes Minne, the Lundberg ... JF, Cooper NS, Healey LA, Kaplan SR, Liang MH, Luthra HS, et al.: The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis Arthritis Rheum 1988, 31:315-324 ... showing the median and the mean ± standard error of the mean Patients' age and disease duration are reported as the mean ± standard deviation P < 0.05 is considered significant Results The levels...
- 8
- 443
- 0
Báo cáo y học: "erum levels of soluble receptor for advanced glycation end products and of S100 proteins are associated with inflammatory, autoantibody, and classical risk markers of joint and vascular damage in rheumatoid arthritis" doc
... their risk factors Materials and methods Subjects The cohort of RA patients met the American College of Rheumatology (ACR) 1987 revised criteria for the classification of RA, and has been previously ... levels were found at the time of the evaluation The percentage risk of coronary heart disease over the next 10 years was estimated using the 'CVD Risk Calculator' based on the Framingham Study ... a stroke was deemed hemorrhagic Body mass index (BMI) was calculated as weight in kilograms divided by the square of the height in meters Blood pressure was measured at the time of evaluation...
- 11
- 420
- 0
Báo cáo y học: ":The expression of the receptor for advanced glycation end-products (RAGE) in RA-FLS is induced by IL-17 via Act-1" ppsx
... purchased from Calbiochem (Schwalbach, Germany) Immunohistochemistry of RA synovium and FLS Immunohistochemical staining was performed on sections of synovium Briefly, the synovial samples were obtained ... in OA synovial tissues (Figure 1a) Strong RAGE expression was detected in the synovial lining and sublining layers and the perivascular area in RA synovial tissues The severity of synovial inflammation ... the stimulatory effect of IL-17 on RAGE expression, in rheumatoid synovium, the expression of RAGE was increased as the final outcome as we observed in immunohistochemical staining of RA synovial...
- 12
- 343
- 0
Báo cáo khoa học: Analysis and biological relevance of advanced glycation end-products of DNA in eukaryotic cells ppt
... transfected HEK 293 T cells To ensure that the observed reduction of the luciferase activity was not a result of cytotoxic activity of the CEdG-modified plasmid DNA, the viability of transfected HEK 293 ... each sample to the mean ratio of the unmodified pGL3 Control vector The results of the luciferase reporter gene assay with the CEdG-modified vector showed that the plasmid with the highest CEdG level ... sufficient sensitivity of the mass analysis, the analytes should elute with a maximal proportion of organic solvent into the ion source On the other hand, the LC should lead to the separation of...
- 12
- 381
- 0
Báo cáo y học: " Soluble receptor for advanced glycation end products in COPD: relationship with emphysema and chronic cor pulmonale: a case-control study" potx
... chest radiographs were obtained in all the subjects at the time of enrollment in the study, and were examined by two chest physicians for the presence of heart and pulmonary abnormalities The ... and testing the null hypothesis that the intercept is equal to zero and the slope is equal to one, jointly We utilized the data from the 200 COPD patients and the 201 age and sex-matched controls ... (table 3) With regard to lung function, there was a significant relationship between sRAGE and the degree of airflow obstruction, the lower the level of sRAGE the greater the airflow obstruction...
- 9
- 417
- 0
Báo cáo y học: "Mechanical ventilation during experimental sepsis increases deposition of advanced glycation end products and myocardial inflammation" pdf
... of the paper JWK performed the animal experiments and contributed to the writing of the paper CDS supervised the animal experiments and contributed to the writing of the paper AS supervised the ... 1:500) Thereafter, the slides were again washed in PBS, followed by 30 minute incubation with anti-rabbit and anti-mouse EnVision-HRP (DakoCytomation, Heverlee, Belgium) The slides were then washed ... multiplied by the number of vessels positive for this score The multiplication scores were then added and the sum was divided by the area of the slide, resulting in a immunohistochemical score...
- 7
- 237
- 0
Báo cáo khoa học: Advanced glycation end products and lipopolysaccharide synergistically stimulate proinflammatory cytokine⁄chemokine production in endothelial cells via activation of both mitogen-activated protein kinases and nuclear factor-jB pdf
... cytokines ⁄ chemokines [11–13] Previous studies have revealed that endothelial cells are also a major target for LPS; with the help of soluble CD14 in the circulation, LPS directly activates endothelial ... permeability of endothelium, thus exaggerating the inflammatory response [20]; the chemoattractants IL-8 and MCP-1 induce leukocyte–endothelial cell adhesion and promote the migration and infiltration ... to the inflammatory loci, which is a key step in inflammation [21,22] Therefore, the cooperation of AGE-HSA and LPS on the induction of cytokines ⁄ chemokines in endothelial cells observed in the...
- 9
- 409
- 0
Báo cáo y học: "Advanced glycation end products induce cell cycle arrest and proinflammatory changes in osteoarthritic fibroblast-like synovial cells" doc
... hours The conditioned media were harvested and stored at -80°C until the measurements were performed Then, cells were detached and counted The results were corrected by the numbers of FLS in the ... in rheumatoid arthritis Rheumatology 2001, 40:302-309 Müller-Ladner U, Ospelt C, Gay S, Distler O, Pap T: Cells of the synovium in rheumatoid arthritis Synovial fibroblasts Arthritis Res Ther ... For preparation of the Master Mix, the FastStart DNA Masterplus SYBR Green I-Kit was used Together with the specific primers, the Master Mix was added to cDNA solutions The cDNA samples were...
- 19
- 395
- 0
Báo cáo y học: " Blockade of advanced glycation end product formation attenuates bleomycin-induced pulmonary fibrosis in rats" pot
... Briefly, the grade of lung fibrosis was scored on a scale of to using the following criteria: grade 0, normal lung; grade to 2, minimal fibrous thickening of alveolar or bronchiolar wall; grade to ... dose-dependent manner To confirm the effect of AG on the histopathological change of bleomycininduced pulmonary fibrosis, the overall grades of the fibrotic changes of the lungs were performed by Ashcroft ... the first time that AGEs may participate in the process of BLM-induced pulmonary fibrosis, at least partly implicated in TGFb/Smads-HSP47 pathway The further study should focus on whether the...
- 8
- 174
- 0
báo cáo hóa học: " Imaging the effect of receptor for advanced glycation endproducts on angiogenic response to hindlimb ischemia in diabetes" docx
... prepared the tracers, performed the experiments, and revised the manuscript JL helped in the acquisition of data DW provided the highresolution gamma imaging device AMS and SFY developed the RAGE-/animal ... significantly higher than the WT diabetic group (P < 0.001) Figure 2B shows values as %ID/g for the four groups for the left and right hindlimbs The counts in the left (ischemic) hindlimbs showed the same ... incision was made on the upper thigh of both the left and right legs of each mouse The inguinal ligament and the upper half of the femoral artery were exposed On the left side, the vascular bundle...
- 9
- 398
- 0
Báo cáo y học: "Green tea polyphenol epigallocatechin-3-gallate inhibits advanced glycation end product-induced expression of tumor necrosis factor-α and matrix metalloproteinase-13 in human chondrocyte" ppsx
... maintain their chondrogenic phenotype We determined whether primary human OA chondrocytes and chondrocytes passaged once used in these studies maintained their phenotype – by analyzing the expression ... that still-healthy cartilage of patients with a focal degenerative cartilage lesion elsewhere in the joint has higher AGE levels than healthy cartilage from control individuals in which there are ... proteins, while many others present protein–protein crosslinks Once AGEs are formed, they cannot be removed from the protein; they only leave a tissue when the protein involved is degraded Articular...
- 13
- 400
- 0
báo cáo hóa học:" RAGE (Receptor for Advanced Glycation Endproducts), RAGE Ligands, and their role in Cancer and Inflammation" pptx
... Response: Winding the Way to the Pathogenesis of Endothelial Dysfunction and Atherosclerosis Ann NY Acad Sci 2008, 1126:7-13 189 Chen Y, Akirav EM, Chen W, Henegariu O, Moser B, Desai D, Shen JM, Webster ... bind other substrates [67,69] It remains to be determined if the action of the A-box is the result of competitive inhibition by binding to other substrates or interfering with the ability of the ... dose-dependent manner when both are added Is HMGB1 the lone RAGE activator of the HMG family? For all the reasons noted above, HMGB1 is the sole known HMG-box ligand of RAGE None of the other nuclear HMG...
- 21
- 626
- 0
Báo cáo y học: "Advanced glycation end-product (AGE)-damaged IgG and IgM autoantibodies to IgG-AGE in patients with early synovitis." ppt
... 3, the IgG-AGE levels were higher in the RA patient group at the initial visit as compared with the other groups studied, whereas the levels were similar in all groups at the year follow-up visit ... pathogenic process or whether they are merely the consequence of damage in the past The amount of AGEdamaged proteins present in an individual reflects not only the synthesis of the AGE, which can ... RF, rheumatoid factor follow up, whereas those positive for anti-IgG-AGE antibodies in the other groups had lower frequencies of such antibodies at the year follow up When the change in the anti-IgG-AGE...
- 9
- 262
- 0
Báo cáo y học: "No evidence of major effects in several Toll-like receptor gene polymorphisms in rheumatoid arthritis" pdf
... (-13.8%) induce a T-helper type isotypic switch in B lymphocytes, which may be involved in the pathogenesis of RA Further evidence of the role for TLR9 comes from the efficacy in RA of chloroquine ... media campaign followed by selection of individuals who fulfilled the 1987 American College of Rheumatology revised criteria for RA A rheumatologist reviewed all clinical data In each of 100 French ... association analysis The Hardy–Weinberg equilibrium was checked in control individuals, using a chi-square test with one degree of freedom The linkage analysis relied on the TDT, in which the observed...
- 10
- 338
- 0
Báo cáo y học: "Vitamin D receptor gene polymorphisms and susceptibility of hand osteoarthritis in Finnish wome" pdf
... To our knowledge, the association between the VDR gene polymorphisms and OA has not been studied in the Finnish population The aim of the present study was to examine whether the VDR polymorphisms, ... examine the association between the VDR genotypes and hand OA To evaluate whether the association between the genotypes and OA is modified by daily calcium intake, the odds ratio (OR) of having OA ... odds and those with the AATT genotype the highest odds of hand osteophytes as compared with the AAtt genotype The direction of these associations contrast the findings in the studies of osteophytes...
- 9
- 613
- 0
Báo cáo y học: "No evidence of major effects in several Toll-like receptor gene polymorphisms in rheumatoid arthritis" ppt
... (-13.8%) induce a T-helper type isotypic switch in B lymphocytes, which may be involved in the pathogenesis of RA Further evidence of the role for TLR9 comes from the efficacy in RA of chloroquine ... media campaign followed by selection of individuals who fulfilled the 1987 American College of Rheumatology revised criteria for RA A rheumatologist reviewed all clinical data In each of 100 French ... association analysis The Hardy–Weinberg equilibrium was checked in control individuals, using a chi-square test with one degree of freedom The linkage analysis relied on the TDT, in which the observed...
- 10
- 339
- 0
Báo cáo y học: " Glucocorticoid receptor gene polymorphisms associated with progression of lung disease in young patients with cystic fibrosis" doc
... carrying the BclI GG genotype These observations are consistent with the effect of GR polymorphism on gene products and the role of GR in the control of the inflammatory response of the lung in ... of the studied polymorphisms with nutritional status and glucose metabolism Several reasons can be put forward to explain these results They include the types and the sensitivity of the phenotypic ... In the present study, we did not find association of the other studied GR polymorphisms with lung disease progression evaluated from the slopes of decline in lung function parameters Neither...
- 9
- 419
- 0
Tài liệu Báo cáo khoa học: Complex transcriptional and translational regulation of iPLA2c resulting in multiple gene products containing dual competing sites for mitochondrial or peroxisomal localization docx
... which regulates the flow of the Gibbs free energy inherent in C–C bonds in fatty acids into the production of either chemical energy or heat by directing the flow of iPLA2c into either the peroxisomal ... indicated on the left AUG most proximal to the polyhedrin baculoviral promoter [38,39] Accordingly, the virtual absence of the 88 kDa protein product was unanticipated To begin identifying the reasons ... scale (kb) The 13 exons of the iPLA2c gene are indicated as boxes Spaces between the exons represent the relative sizes of the 12 introns contained within the iPLA2c gene Regions of the gene that...
- 16
- 438
- 0
Toll-like receptor 2 gene polymorphisms, pulmonary tuberculosis, and natural killer cell counts pot
... analyzed the data, and critically revised and approved the manuscript CJC elaborated the design of the study HE performed the flowcytometric analysis CHC, SL, CW, TC, YW, and CT recruited the study ... method, which searches for a “spine” of strong LD running from one marker to another along the legs of the triangle in the LD chart, and the haplotype frequencies were estimated using the expectation-maximization ... [20,21] The difference in the genotypic distribution between the TB phenotypes was evaluated in a dominant model by a c test in which the wild-type and heterozygote variant were compared with the homozygote...
- 10
- 371
- 0
Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo gắn với các giáo trình cụ thể điều tra đối với đối tượng giảng viên và đối tượng quản lí nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25