... after incubation of cells with TUDCA. In contrast, DCA and TDCA induced apoptosis but did not significantly change cyclin D1 and E-cadherin proteins, or cyclin D1 transcriptional activation. In conclusion, ... the media; but because that is the way science can ensure a balanced public debate where the public have access to accu- rate, good, evidence-based science and the scienti c approach to new developments. ... Genentech Inc., South San Francisco, CA, USA, 3 Department of Bioinformatics, Genentech Inc., South San Francisco, CA, USA, 4 Department of Molecular Biology, Genentech Inc., South San Francisco, CA, USA, 5 Department...
Ngày tải lên: 23/03/2014, 15:20
... Education, Culture, Sports, Science and Technology; the Japan Society for the Promotion of Science; and the Japan Science and Technology Agency. References 1 Pawson T & Nash P (2000) Protein protein ... FEBS Interaction between very-KIND Ras guanine exchange factor and microtubule-associated protein 2, and its role in dendrite growth – structure and function of the second kinase noncatalytic C- lobe ... GST CD2-1 CD2-2 CD2-3 CD2 PD 250 150 Input GST CD2-1-6-1 CD2-1-6-2 CD2-1-6-3 CD2-1 PD IB: -v-KIND 250 150 Input GST CD2-1-5 CD2-1-6 CD2-1-7 CD2-1-8 CD2-1 PD 250 Input GST CD2-1-1 CD2-1-2 CD2-1-3 CD2-1-4 CD2-1 PD 250 150 MAP2 MBD RII CD1 CD2 CD3 1–147 148–599 600–1099 1100–1518 1519–1829 767 934 CD2-1 CD2-2 CD2-3 600 CD2 1099 Inter- action 600...
Ngày tải lên: 14/02/2014, 19:20
Báo cáo khoa học: NMR solution structure and function of the C-terminal domain of eukaryotic class 1 polypeptide chain release factor pdf
... the final 48 calculated structures. Twenty-four structures of the closed protein conformer are shown in red, and 24 structures of the open conformer are shown in cyan. The N-termini and C- termini are ... pelleted with ice-cold 5% trichloroacetic acid, supplemented with 0.75% casamino acids, and centrifuged at 4 C and 14 000 g. The amount of released [ 35 S]Met-containing tetra- peptide, which indicated ... HN and the Ca signals, correlating the amide HN and the Ca signal of the preceding amino acid, correlating the amide NH with the Ca and Cb signals, correlating the amide NH with the Ca and Cb...
Ngày tải lên: 06/03/2014, 11:20
Báo cáo khoa học: Evolutionary changes to transthyretin: structure and function of a transthyretin-like ancestral protein doc
... (E .C. 3.5.2). Other cyclic amidohydrolases include hydantoinase, allantoinase and dihydrooratase [32]. Cyclic amidohydrolases share a number of physicochemical characteristics. These characteristics ... tetrameric structure. Acta Biochim Pol 44, 505–517. 36 Sunde M, Richardson SJ, Chang L, Pettersson TM, Schreiber G & Blake CC (1996) The crystal structure of transthyretin from chicken. Eur J Biochem ... remark- able conservation of the prealbumin-like fold (as described by SCOP, http://scop.mrc-lmb.cam.ac.uk), which consists of an eight-stranded b-sandwich (strands A-H) with each sheet adopting...
Ngày tải lên: 07/03/2014, 00:20
Role of C-Reactive Protein and Procalcitonin in Differentiation of Tuberculosis from Bacterial Community Acquired Pneumonia potx
... percentages. Figure 2. C- reactive protein (CRP) and procalcitonin (PCT) concentration according to the pneumonia severity index in bacterial community-acquired pneumonia. Patients in risk classes ... significant positive correlation was detected between the CRP and PCT concentrations ( r=0.648, p=0.01). Diagnostic accuracy for discriminating TB from bacterial CAP In the ROC curve analysis, the CRP ... CRP concentration had a Kang YA, et al. C- reactive protein and procalcitonin for the diagnosis of tuberculosis 339 Table 1. Clinical and laboratory characteristics of the participants Bacterial...
Ngày tải lên: 22/03/2014, 18:20
Statin Therapy, LDL Cholesterol, C-Reactive Protein, and Coronary Artery Disease pot
... Clinical application of C- reactive protein for cardiovascular disease detection and prevention. Circulation 2003; 107:363-9. 9. Ridker PM, Hennekens CH, Buring JE, Rifai N. C- reactive protein and ... Stryer DB, Clancy CM. Practical clinical trials: increasing the value of clinical research for decision making in clinical and health policy. JAMA 2003;290:1624-32. Copyright © 2007 Massachusetts ... endothelial cells through shedding of L-selectin by C- reactive protein and pep- tides derived from C- reactive protein. J Clin Invest 1997;100:522-9. 25. Torzewski M, Rist C, Mortensen RF, et al. C- reactive...
Ngày tải lên: 27/06/2014, 00:20
Báo cáo y học: "Plasmatic B-Type Natriuretic Peptide and C-Reactive Protein in Hyperacute Stroke as Markers of Ct-Evidence of Brain Edema." pptx
... E, DeMaat MP. C- reactive protein in atherosclerosis: A causal factor? Cardiovasc Res. 2006; 71: 30-39. 24. Yip HK, Sun CK, Chang LT, Chen MC, Liou CW. Time course and prognostic value of plasma ... 12. Among ischemic strokes 6 were cardioembolic, 7 were lacunar, and the remainder (16) were ischemic non-cardioembolic (11 atherosclerotic and 5 of undetermined cause). The location of stroke ... ischemic stroke. J Neurol Sci. 2005; 236: 65-71. 19. Masotti L, Ceccarelli E, Forconi S, Cappelli R. Prognostic role of C- reactive protein in very old patients with acute ischemic stroke. J Intern...
Ngày tải lên: 08/08/2014, 16:23
Báo cáo y học: " Significant association between Helicobacter pylori infection and serum C-reactive protein" docx
... the bacterium. C- reactive protein (CRP) is an acute-phase reac- tant that originates from the liver. CRP has many clinical and biological effects and can be used for the diagnosis and follow-up ... inflammatory and immune responses with release of various bacterial and host-dependent cytotoxic substances [2], resulting in chronic gastritis, peptic ulcer, and gastric cancer [3]. Epidemiological ... inflammation can have sys- temic effects; (ii) H. pylori gastric infection is a chronic process that lasts for decades; and (iii) persistent in- fection induces chronic inflammatory and immune...
Ngày tải lên: 08/08/2014, 17:20
báo cáo khoa học: "Clinical significance of preoperative serum interleukin-6 and C-reactive protein level in breast cancer patients" pot
... a prognosis factor in metastatic renal cell carcinoma. Cancer Res 1992, 52:3317-3322. 5. Scambia G, Testa U, Benedetti Panici P, Foti E, Martucci R, Gadducci A, Perillo A, Facchini V, Peschle C, Mancuso ... prognostic factor in advanced non- small cell lung cancer. Oncol Rep 1998, 5:649-652. 7. Erlinger TP, Platz EA, Rifai N, Helzlsouer KJ: C- reactive protein and the risk of incident colorectal cancer. ... Stenkvist B: Breast cancer: prognostic significance of c- erb-B2 and int-2 amplification compared with DNA ploidy, S-phase fraction, and conventional clinicopathological features. Breast Cancer Res Treat...
Ngày tải lên: 09/08/2014, 01:24
Báo cáo y học: " C-reactive protein does not opsonize early apoptotic human neutrophils, but binds only membrane-permeable late apoptotic cells and has no effect on their phagocytosis by macrophages" pot
... i.dransfield@ed.ac.uk * Corresponding author Abstract Background: It has been reported that C- reactive protein (CRP) binds both leukocyte FcγRIIA (CD32) and the plasma membrane of apoptotic cells. Since FcγRIIA ... Hirschfield GM: C- reactive protein: a critical update. J Clin Invest 2003, 111:1805-1812. 9. Gershov D, Kim S, Brot N, Elkon KB: C- Reactive protein binds to apoptotic cells, protects the cells ... for providing the FcγRIIA-transfected Jurkat cells, and to Linda Wilson for operating the confocal microscope. This work was funded by a Medical Research Council Clinician Scientist Fel- lowship...
Ngày tải lên: 11/08/2014, 08:21
Báo cáo y học: "Serum levels of autoantibodies against C-reactive protein correlate with renal disease activity and response to therapy in lupus nephritis" pps
... against C- reactive protein and other acute phase proteins. Clin Chim Acta 2007, 378:13-23. 13. Marnell L, Mold C, Du Clos TW: C- reactive protein: ligands, receptors and role in inflammation. Clin ... inflammation, CRP dissoci- ates to mCRP, which may enhance binding of circulating soluble immune complexes to phagocytic Fcγ receptors [12,43] and constitute a vicious circle. Conclusions We have ... microscopy, immunofluorescence and elec- tron microscopy. The biopsies were graded according to a standardized semiquantitative histological scoring protocol for activity and chronicity indices...
Ngày tải lên: 12/08/2014, 11:22
Báo cáo khoa học: "Procalcitonin and C-reactive protein during systemic inflammatory response syndrome, sepsis and organ dysfunctio" pdf
Ngày tải lên: 12/08/2014, 20:20
Bạn có muốn tìm thêm với từ khóa: